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The map label for this gene is ugcG

Identifier: 159184927

GI number: 159184927

Start: 1790521

End: 1791663

Strand: Direct

Name: ugcG

Synonym: Atu1808

Alternate gene names: NA

Gene position: 1790521-1791663 (Clockwise)

Preceding gene: 15889110

Following gene: 15889112

Centisome position: 63.01

GC content: 63.6

Gene sequence:

>1143_bases
ATGGAAACCGTCTTTGCCCTTTGCGCAATTATGCTCCTCGCCTTCAATCTTCTCGGCATTGTTCTCGCCGGCTGGCGACT
GACGAGACGGGACGCGGAAAACGATCTTGTCCGGCAAAAGCCGCCGGTCTCGCTGGTGGTGCCGCTACGCGGCGTCGAAA
ACTTCACGCCGCTGACGCTCTCGCGTGCCTTCGGGCTCGACTGGCCGGATTACGAGTTGCTGTTCTGCGTCGCGGACGAA
TTCGATCCCGTGATCGCGGAAGTCCGCAAAGCCGCCGCCGCATTTCCCTCGGTCTCCATGCAATTGCTGATCGGTGACGA
CCGCGTCAGCGCCAATCCGAAGCTGAACAATTGCGTCAAGGGCTGGCGCGCCGCCAAATATGAATGGGTGATTCTCGCCG
ATTCAAACGTGCTGATGCCGAAATCCTATATAGCCACCATGATGTCGGCCTGGCGGCCGGATAGCGGGCTGGTCTGCTCT
CCGCCGCTCGGTTCCCGCCCTGTGGGATTCTGGGCCAATGTGGAATGCGCCTTCCTCAATGGCTCGCAGGGCCGCTGGCA
ATATGCAGCGGAAGCGATCGGCATCGGTTTCGCACAGGGCAAATCGATGTTGTGGAACAAGCCGTTCCTGGAGGACCGTG
GCGGCATTCGCGCACTCGCCGCCGAAATCGCCGAGGACGCCGCCTCGACGAAGCTGGTGCGGAGCGCCGGCCGCAAGGTG
CATCTGGTCTCCGCCCCGTTCGAGCAACCGCTCGGCCAGCGCCATGCCGGCGAAATCTGGTCACGCCAAACCCGCTGGGC
GCGGCTGAGACGCGTGACCTTTCCGCAATATTTCGCACCGGAAATCCTGACCGGCGCGCTGCCGCCGCTTCTTTTCGCGC
TTGCCGCCACCGCCATGATGGATGTGAACCTCGCCGCGACCGCCTCTGTCGTCCTAGCCCTCATGTTCGGCCCGGAACTG
GCGCTCGCTGCCCTCAATGGCTGGCCAGTGTCGCTCTATACGCTGCCGGCCATGATCGCCCGCGACCTGATCATGCCCGT
CGTCTGGGCGCGCAGCTGGATCGGCAGCGCGGTGGCCTGGCGCGGCAATGTCATGACGATCGGGACGGCGGAGAGTACTC
TGGCGGGTCCGCCTGCGGAATAA

Upstream 100 bases:

>100_bases
ACATGTAACTGTCACGCAAACGTTATAATCGGCAGAGACGAATTCCATGGAATCGATTGGCGGGTGAACCGCCGAAAGCT
TGGGAGTGGAACTGGCCAGC

Downstream 100 bases:

>100_bases
TTGAGAATATTTCCTGGGAGTTACGCCGGAAAGCTGATGTTCAGCTTTAAAATGGTCGGAGTGGAGAGATTCGAACTCCC
GACCCTCTGGTCCCAAACCA

Product: UDP-glucose:ceramide glycosyltransferase

Products: UDP; D-glucosyl-N-acylsphingosine

Alternate protein names: Glycosyltransferase; Glycosyl Transferase Family Protein; Cell Wall Biosynthesis Glycosyltransferase-Like Protein; Glycosyl Transferase Group 2 Family; Glycosyl Transferase; Cell Wall Biosynthesis Glycosyltransferase; UDP-GlucoseCeramide Glycosyltransferase; Glycosyl Tranferase Homolog; Glycosyl Transferase Group 2 Family Protein; Glucosyltransferase

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
METVFALCAIMLLAFNLLGIVLAGWRLTRRDAENDLVRQKPPVSLVVPLRGVENFTPLTLSRAFGLDWPDYELLFCVADE
FDPVIAEVRKAAAAFPSVSMQLLIGDDRVSANPKLNNCVKGWRAAKYEWVILADSNVLMPKSYIATMMSAWRPDSGLVCS
PPLGSRPVGFWANVECAFLNGSQGRWQYAAEAIGIGFAQGKSMLWNKPFLEDRGGIRALAAEIAEDAASTKLVRSAGRKV
HLVSAPFEQPLGQRHAGEIWSRQTRWARLRRVTFPQYFAPEILTGALPPLLFALAATAMMDVNLAATASVVLALMFGPEL
ALAALNGWPVSLYTLPAMIARDLIMPVVWARSWIGSAVAWRGNVMTIGTAESTLAGPPAE

Sequences:

>Translated_380_residues
METVFALCAIMLLAFNLLGIVLAGWRLTRRDAENDLVRQKPPVSLVVPLRGVENFTPLTLSRAFGLDWPDYELLFCVADE
FDPVIAEVRKAAAAFPSVSMQLLIGDDRVSANPKLNNCVKGWRAAKYEWVILADSNVLMPKSYIATMMSAWRPDSGLVCS
PPLGSRPVGFWANVECAFLNGSQGRWQYAAEAIGIGFAQGKSMLWNKPFLEDRGGIRALAAEIAEDAASTKLVRSAGRKV
HLVSAPFEQPLGQRHAGEIWSRQTRWARLRRVTFPQYFAPEILTGALPPLLFALAATAMMDVNLAATASVVLALMFGPEL
ALAALNGWPVSLYTLPAMIARDLIMPVVWARSWIGSAVAWRGNVMTIGTAESTLAGPPAE
>Mature_380_residues
METVFALCAIMLLAFNLLGIVLAGWRLTRRDAENDLVRQKPPVSLVVPLRGVENFTPLTLSRAFGLDWPDYELLFCVADE
FDPVIAEVRKAAAAFPSVSMQLLIGDDRVSANPKLNNCVKGWRAAKYEWVILADSNVLMPKSYIATMMSAWRPDSGLVCS
PPLGSRPVGFWANVECAFLNGSQGRWQYAAEAIGIGFAQGKSMLWNKPFLEDRGGIRALAAEIAEDAASTKLVRSAGRKV
HLVSAPFEQPLGQRHAGEIWSRQTRWARLRRVTFPQYFAPEILTGALPPLLFALAATAMMDVNLAATASVVLALMFGPEL
ALAALNGWPVSLYTLPAMIARDLIMPVVWARSWIGSAVAWRGNVMTIGTAESTLAGPPAE

Specific function: Unknown

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4507811, Length=273, Percent_Identity=30.03663003663, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25147526, Length=380, Percent_Identity=25, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI25149577, Length=373, Percent_Identity=24.9329758713137, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32564728, Length=373, Percent_Identity=24.6648793565684, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25149574, Length=373, Percent_Identity=24.9329758713137, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25149580, Length=293, Percent_Identity=26.2798634812287, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32566973, Length=334, Percent_Identity=24.8502994011976, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24657569, Length=282, Percent_Identity=32.2695035460993, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.1.80

Molecular weight: Translated: 41440; Mature: 41440

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVFALCAIMLLAFNLLGIVLAGWRLTRRDAENDLVRQKPPVSLVVPLRGVENFTPLTL
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCEEEEECCCCCCCCCCEE
SRAFGLDWPDYELLFCVADEFDPVIAEVRKAAAAFPSVSMQLLIGDDRVSANPKLNNCVK
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHH
GWRAAKYEWVILADSNVLMPKSYIATMMSAWRPDSGLVCSPPLGSRPVGFWANVECAFLN
HHHCCCEEEEEEECCCEECCHHHHHHHHHHCCCCCCCEECCCCCCCCCCEEECEEEEEEE
GSQGRWQYAAEAIGIGFAQGKSMLWNKPFLEDRGGIRALAAEIAEDAASTKLVRSAGRKV
CCCCCHHHHHHHHHCCHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
HLVSAPFEQPLGQRHAGEIWSRQTRWARLRRVTFPQYFAPEILTGALPPLLFALAATAMM
EEEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DVNLAATASVVLALMFGPELALAALNGWPVSLYTLPAMIARDLIMPVVWARSWIGSAVAW
HCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
RGNVMTIGTAESTLAGPPAE
CCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
METVFALCAIMLLAFNLLGIVLAGWRLTRRDAENDLVRQKPPVSLVVPLRGVENFTPLTL
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCEEEEECCCCCCCCCCEE
SRAFGLDWPDYELLFCVADEFDPVIAEVRKAAAAFPSVSMQLLIGDDRVSANPKLNNCVK
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHH
GWRAAKYEWVILADSNVLMPKSYIATMMSAWRPDSGLVCSPPLGSRPVGFWANVECAFLN
HHHCCCEEEEEEECCCEECCHHHHHHHHHHCCCCCCCEECCCCCCCCCCEEECEEEEEEE
GSQGRWQYAAEAIGIGFAQGKSMLWNKPFLEDRGGIRALAAEIAEDAASTKLVRSAGRKV
CCCCCHHHHHHHHHCCHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
HLVSAPFEQPLGQRHAGEIWSRQTRWARLRRVTFPQYFAPEILTGALPPLLFALAATAMM
EEEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DVNLAATASVVLALMFGPELALAALNGWPVSLYTLPAMIARDLIMPVVWARSWIGSAVAW
HCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
RGNVMTIGTAESTLAGPPAE
CCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-glucose; N-acylsphingosine

Specific reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA