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The map label for this gene is nuoG [H]

Identifier: 159184690

GI number: 159184690

Start: 1262252

End: 1264333

Strand: Direct

Name: nuoG [H]

Synonym: Atu1276

Alternate gene names: 159184690

Gene position: 1262252-1264333 (Clockwise)

Preceding gene: 15888604

Following gene: 15888606

Centisome position: 44.42

GC content: 61.38

Gene sequence:

>2082_bases
ATGGCAAAGCTCAAGGTTGACGGTAAAGAGATCGAGGTTCCGGATCATTTCACGCTGTTGCAGGCGTGCGAGGAGGCTGG
TGCCGAAGTTCCGCGCTTTTGTTTTCATGAGCGCTTGTCGGTCGCGGGTAACTGCCGCATGTGTCTCATCGAGGTGAAGG
GCGGACCACCGAAGCCGGCCGCCTCCTGCGCCATGGGCGTGCGCGATGTTCGCGGCGGCCCGAATGGCGAATTGCCTGAG
GTTTTCACCAACACACCGATGGTCAAAAAGGCCCGCGAAGGTGTGATGGAGTTCCTGCTCATCAACCACCCGCTCGATTG
CCCGATCTGCGACCAGGGCGGCGAATGCGACCTGCAGGACCAGGCCATGGCCTTCGGTATCGCCGGTTCGCGTTACGCGG
AAAACAAGCGCGCGGTTGAAGACAAATATATCGGCCCGCTCGTCAAGACGGTCATGAACCGCTGCATTCACTGCACGCGC
TGCGTCCGTTTCACCACGGAAGTGGCCGGCATTGCCGAACTCGGCCTCATCGGCCGCGGCGAAGATGCCGAAATCACCAC
CTATCTCGAACAGGCCATGACGTCTGAGCTTCAGGGCAACGTCGTCGACCTTTGCCCGGTTGGTGCGCTCACTTCCAAGC
CATTCGCTTTCACCGCCCGTCCGTGGGAACTGAACAAGACCGAAACCATCGACGTGATGGACGCGCTCGGTTCGGCCATC
CGCGTCGATACCCGTGGCCGCGAAGTCATGCGCGTCATGCCGCGTGTCAACGAGGCGATCAACGAAGAGTGGATTTCCGA
CAAGAGCCGCTTCATCTGGGACGGCCTGAAGACGCAGCGCCTCGACCGGCCTTACGTCCGCAAGGATGGCCGGCTGCAGC
CCGCCACTTGGGGCGAAGCCTTTGGCGCCATCAAGCAGGCTGTAGCCGCAACGTCGGGTTCGAAAATTGGCGCAATCGCC
GGCGATCTGTCCTCCGTCGAAGAGATGTTCGCGCTGAAGTCGCTGCTCGCTTCGCTCGGCTCGGCCAATGTCGATTGCCG
TCAGGATGGCGCAGCGCTTGATCCGTCTTTGGGTCGTGCCAGCTATATCTTCAATTCCACTATTGAAGGCATCGAACACG
CCGACGCTCTGCTGATCGTTGGTTCCAACCCGCGCTTCGAAGCGGCCGTGCTCAACGCCCGCATCCGCAAGCGCTGGCGT
CGCGGCGGTTTCCCGATCGGTGTGATCGGTGAGGCCGGTGAGCTGCGCTACAATTACGAATATCTCGGCTCGGGCGCGGA
AACGCTTTCCGATCTCGCCAATGGCTCGCACAGCTTCATCGACAAGCTGAAATCCGCCAAGAACCCACTGATCATCATCG
GTCAGGGCGCTCTGGCACGTGCCGATGGTGCTGCCGTTCTCGCGGCTGCTGCAAAACTTGCCGTTTCGGTTGGCGCTGTC
ACCGAAGAGTGGAATGGCTTCTCGGTGTTGCACACTGCGGCTGCCCGCGTCGGCGGTCTCGATATCGGCTTCGTGCCGGG
CGAGGGCGCTGTTGCTGCCGCCGAGATGGTGACGTCCATGGACGTCCTGTTCCTACTCGGCGCCGATGAAATTGACCTGT
CCAACAAGGGCGCCAAGTTCACCGTCTATATCGGCAGCCACGGCGATCAGGGCGCGATGAACGCCGACGTCATCCTTCCG
GGTGCGGCCTATACCGAAAAATCCGGTATCTGGGTCAACACCGAAGGCCGTGTTCAGGTGGGCAACCGCGCCGGTTTCGC
GCCGGGCGAAGCCCGTGAAGACTGGGCGATCCTGCGCGCGCTGTCCGACGTGCTCGGCAAAAAGCTGCCGTTCGATTCGC
TGTCTGCCCTGCGCGGCCAGCTTTATGTCGCGCATCCGCATCTGGCGGAAACCGACGAGATCGTTGCCGGCAAGGCCACG
GATATCGAGGCGCTGGCTGGTAAAACCGGCTCGCTCACGAAGTCGGCGTTTGCCTCGCCGGTAAAAGACTTTTATTTGAC
GAACCCGATTGCGCGCGCCTCAGCTGTGATGGCCGAGTGCTCCGCATTGGCCCGCAACAATTTCCAGGCTGCGGCAGAGT
AA

Upstream 100 bases:

>100_bases
TGAAGCGCCTGGCGAAACTCTGGATGCCTGGCGTGATTAAGGATTTGTTGCGGACCGTGTGAGACATGGGACGAACAGGC
AACAGGACGTAAGTAGAACC

Downstream 100 bases:

>100_bases
GGGTAGGGGATTTATGGAACAGTTTTTCTGGAGCTACGTCTGGCCCGCGCTGATCATGGTCGGCCAGTCCCTGCTGCTTC
TCGTTTGCCTTCTGGTGGCC

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 3; NDH-1, chain 3 [H]

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MAKLKVDGKEIEVPDHFTLLQACEEAGAEVPRFCFHERLSVAGNCRMCLIEVKGGPPKPAASCAMGVRDVRGGPNGELPE
VFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAFGIAGSRYAENKRAVEDKYIGPLVKTVMNRCIHCTR
CVRFTTEVAGIAELGLIGRGEDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTETIDVMDALGSAI
RVDTRGREVMRVMPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRKDGRLQPATWGEAFGAIKQAVAATSGSKIGAIA
GDLSSVEEMFALKSLLASLGSANVDCRQDGAALDPSLGRASYIFNSTIEGIEHADALLIVGSNPRFEAAVLNARIRKRWR
RGGFPIGVIGEAGELRYNYEYLGSGAETLSDLANGSHSFIDKLKSAKNPLIIIGQGALARADGAAVLAAAAKLAVSVGAV
TEEWNGFSVLHTAAARVGGLDIGFVPGEGAVAAAEMVTSMDVLFLLGADEIDLSNKGAKFTVYIGSHGDQGAMNADVILP
GAAYTEKSGIWVNTEGRVQVGNRAGFAPGEAREDWAILRALSDVLGKKLPFDSLSALRGQLYVAHPHLAETDEIVAGKAT
DIEALAGKTGSLTKSAFASPVKDFYLTNPIARASAVMAECSALARNNFQAAAE

Sequences:

>Translated_693_residues
MAKLKVDGKEIEVPDHFTLLQACEEAGAEVPRFCFHERLSVAGNCRMCLIEVKGGPPKPAASCAMGVRDVRGGPNGELPE
VFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAFGIAGSRYAENKRAVEDKYIGPLVKTVMNRCIHCTR
CVRFTTEVAGIAELGLIGRGEDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTETIDVMDALGSAI
RVDTRGREVMRVMPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRKDGRLQPATWGEAFGAIKQAVAATSGSKIGAIA
GDLSSVEEMFALKSLLASLGSANVDCRQDGAALDPSLGRASYIFNSTIEGIEHADALLIVGSNPRFEAAVLNARIRKRWR
RGGFPIGVIGEAGELRYNYEYLGSGAETLSDLANGSHSFIDKLKSAKNPLIIIGQGALARADGAAVLAAAAKLAVSVGAV
TEEWNGFSVLHTAAARVGGLDIGFVPGEGAVAAAEMVTSMDVLFLLGADEIDLSNKGAKFTVYIGSHGDQGAMNADVILP
GAAYTEKSGIWVNTEGRVQVGNRAGFAPGEAREDWAILRALSDVLGKKLPFDSLSALRGQLYVAHPHLAETDEIVAGKAT
DIEALAGKTGSLTKSAFASPVKDFYLTNPIARASAVMAECSALARNNFQAAAE
>Mature_692_residues
AKLKVDGKEIEVPDHFTLLQACEEAGAEVPRFCFHERLSVAGNCRMCLIEVKGGPPKPAASCAMGVRDVRGGPNGELPEV
FTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAFGIAGSRYAENKRAVEDKYIGPLVKTVMNRCIHCTRC
VRFTTEVAGIAELGLIGRGEDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTETIDVMDALGSAIR
VDTRGREVMRVMPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRKDGRLQPATWGEAFGAIKQAVAATSGSKIGAIAG
DLSSVEEMFALKSLLASLGSANVDCRQDGAALDPSLGRASYIFNSTIEGIEHADALLIVGSNPRFEAAVLNARIRKRWRR
GGFPIGVIGEAGELRYNYEYLGSGAETLSDLANGSHSFIDKLKSAKNPLIIIGQGALARADGAAVLAAAAKLAVSVGAVT
EEWNGFSVLHTAAARVGGLDIGFVPGEGAVAAAEMVTSMDVLFLLGADEIDLSNKGAKFTVYIGSHGDQGAMNADVILPG
AAYTEKSGIWVNTEGRVQVGNRAGFAPGEAREDWAILRALSDVLGKKLPFDSLSALRGQLYVAHPHLAETDEIVAGKATD
IEALAGKTGSLTKSAFASPVKDFYLTNPIARASAVMAECSALARNNFQAAAE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=707, Percent_Identity=49.6463932107496, Blast_Score=677, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=387, Percent_Identity=29.9741602067183, Blast_Score=180, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17565758, Length=700, Percent_Identity=48.8571428571429, Blast_Score=622, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI32566231, Length=587, Percent_Identity=51.1073253833049, Blast_Score=566, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI193209088, Length=258, Percent_Identity=59.6899224806201, Blast_Score=319, Evalue=4e-87,
Organism=Drosophila melanogaster, GI24640559, Length=690, Percent_Identity=50.2898550724638, Blast_Score=643, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=690, Percent_Identity=50.2898550724638, Blast_Score=643, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 73881; Mature: 73750

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLKVDGKEIEVPDHFTLLQACEEAGAEVPRFCFHERLSVAGNCRMCLIEVKGGPPKPA
CCEEECCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCH
ASCAMGVRDVRGGPNGELPEVFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQD
HHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QAMAFGIAGSRYAENKRAVEDKYIGPLVKTVMNRCIHCTRCVRFTTEVAGIAELGLIGRG
CHHEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTETIDVMDALGSAI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHCCCCE
RVDTRGREVMRVMPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRKDGRLQPATWGEA
EECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHH
FGAIKQAVAATSGSKIGAIAGDLSSVEEMFALKSLLASLGSANVDCRQDGAALDPSLGRA
HHHHHHHHHHCCCCCCEEHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
SYIFNSTIEGIEHADALLIVGSNPRFEAAVLNARIRKRWRRGGFPIGVIGEAGELRYNYE
HHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECHH
YLGSGAETLSDLANGSHSFIDKLKSAKNPLIIIGQGALARADGAAVLAAAAKLAVSVGAV
HHCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCH
TEEWNGFSVLHTAAARVGGLDIGFVPGEGAVAAAEMVTSMDVLFLLGADEIDLSNKGAKF
HHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCEE
TVYIGSHGDQGAMNADVILPGAAYTEKSGIWVNTEGRVQVGNRAGFAPGEAREDWAILRA
EEEEECCCCCCCCCCCEEECCCCEECCCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHH
LSDVLGKKLPFDSLSALRGQLYVAHPHLAETDEIVAGKATDIEALAGKTGSLTKSAFASP
HHHHHCCCCCHHHHHHHCCEEEEECCCCCCCCCEECCCCCCHHHHCCCCCCCCHHHHHHH
VKDFYLTNPIARASAVMAECSALARNNFQAAAE
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKLKVDGKEIEVPDHFTLLQACEEAGAEVPRFCFHERLSVAGNCRMCLIEVKGGPPKPA
CEEECCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCH
ASCAMGVRDVRGGPNGELPEVFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQD
HHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QAMAFGIAGSRYAENKRAVEDKYIGPLVKTVMNRCIHCTRCVRFTTEVAGIAELGLIGRG
CHHEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTETIDVMDALGSAI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHCCCCE
RVDTRGREVMRVMPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRKDGRLQPATWGEA
EECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHH
FGAIKQAVAATSGSKIGAIAGDLSSVEEMFALKSLLASLGSANVDCRQDGAALDPSLGRA
HHHHHHHHHHCCCCCCEEHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
SYIFNSTIEGIEHADALLIVGSNPRFEAAVLNARIRKRWRRGGFPIGVIGEAGELRYNYE
HHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECHH
YLGSGAETLSDLANGSHSFIDKLKSAKNPLIIIGQGALARADGAAVLAAAAKLAVSVGAV
HHCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCH
TEEWNGFSVLHTAAARVGGLDIGFVPGEGAVAAAEMVTSMDVLFLLGADEIDLSNKGAKF
HHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCEE
TVYIGSHGDQGAMNADVILPGAAYTEKSGIWVNTEGRVQVGNRAGFAPGEAREDWAILRA
EEEEECCCCCCCCCCCEEECCCCEECCCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHH
LSDVLGKKLPFDSLSALRGQLYVAHPHLAETDEIVAGKATDIEALAGKTGSLTKSAFASP
HHHHHCCCCCHHHHHHHCCEEEEECCCCCCCCCEECCCCCCHHHHCCCCCCCCHHHHHHH
VKDFYLTNPIARASAVMAECSALARNNFQAAAE
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1605643; 8422400 [H]