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The map label for this gene is mcpA [H]

Identifier: 159184404

GI number: 159184404

Start: 634672

End: 636495

Strand: Reverse

Name: mcpA [H]

Synonym: Atu0646

Alternate gene names: 159184404

Gene position: 636495-634672 (Counterclockwise)

Preceding gene: 159185417

Following gene: 159184398

Centisome position: 22.4

GC content: 62.06

Gene sequence:

>1824_bases
ATGAAGAACCTTTCCATTTCCCGTCAACTGATCGTTCTCGTGGTGGCCCTGATGGCCGCCTTCGGCGCGGCGACCTTCTA
CCAGCTGAAATCCGCCACCGATGCGATCTATGAGGAACGCTACGGCATGCTGCGGACGCAGGTGCAATCCGCAATCTCCA
TCCTGCAATCCTTCCATGACAAGGAAAAGGCCGGGACGCTTTCGCGCGACGAGGCCATGAAACAGGCTTACGCGACCGTC
AGCGCCATGCGCTTCACTCCCGATGGCTATCTTTTCGGTTACGACTACGACGTGACGATGAAATTCCATCCCGATACAAA
ACGGGTCGGGGAAAACTACAAGGGTAAGCCCGACAGCAAGGGCTTTGCCTATCGTGACGAACTGGTGCGGCTTGGTCGCA
ATGGCGGCGGGCAGACGGATTTCTACGGTCCGAAGCCTGGCATGGAAGGCAATGATTACGCCAAGAGCTCCTACGCGCTG
GCCTTCGAGCCCTGGCAGGTGGTGGTCGTGACCGGCGTTTACATCGACGATCTGAATGCGCAGGTTCGTGGTGAGGTGAT
GAAAGCGCTGTCCATTGGCGCGCTCATCTTCGTGCTGGCGCTTGCCGCCGCCTTCTACGTCATCCGCGGCATTTCGAAAC
CGCTCGGCGACATTCACCGCGCGCTCGGCGAAGTGGCCAATGAGAACGTTTCGCTCGCCATTCCCCACACCGGCCTGACC
AACGAAGTGGGCATGATGGCCAAGGCCACCGCCTCGCTGCAGGACAAGGTGCGCGAGCGCCATGCCATGCAGCGCCGTGA
GGAAGAGCAGCAGCAGCAGCTCGATGCCGAGCGCCAGAACAATCTCGACATGCAGCGCGACGAGGCCGCATTGCAGGCGC
GGGTCGTCGCCACGATCGGCGAAGCGCTGGAGAAGCTGGCCGGTGGTGATCTGACCGTGCGCTGCGGCGATCTCGGCAAC
CGTTATGCGGCGCTGCGCGACAATTTCAACGAGGCTCTGACGCATCTCGATGCCGCCATGGCCAAGGTGAACACCAAGAG
CATCGATATTGGCGGCTCGAAGGACGAAATCCGCAAGGCTTCGAACGAGCTTTCGCAGCGCACCGAACGGCAGGCCGCAA
ATCTGGAGGAAACCTCCGCGGCTCTCGATGAACTGACGGTTGCGGTGCGCCAGACGGCGGAAGGTGCAGCTGACGCCGCC
AAGCGCGTCACCACCGTCAGCTCGGAAGCGACGCGCAGCGACCGGGTGGTGGAAGAGGCGATCACGGCGATGAGCGGTAT
CGAACAATCCTCCGACCAGATTTCCAACATTATCGGCGTGATCGACGTCATCGCCTTCCAGACCAACCTTCTGGCGCTGA
ATGCCGGCGTGGAAGCAGCCCGTGCGGGCGAAGCCGGCAAGGGTTTTGCCGTGGTGGCGCAGGAAGTGCGCGAACTGGCG
CAGAAATCCGCCGCCGCCGCCAAGGAGATCAAGGACCAGATCGCCCGCTCTTCGGCCCAGGTGGAAAACGGCGTGCGCCT
TGTCGGCGAGGCTGGCGACGCGCTGAAACGCATCTCGGACCAGATCAAATCCGCCAACGAGATCGTCAGCAAGATCGCCC
ATTCGGCCGCCGAACAGGATACGACCCTGCGTTCGATCTCCACGTCGCTGAACCAACTCGATGTCGCCACCCAGCACAAT
GCGGCGATGGCGGAAGAGACCACGGCTTCGGCGGAAGCGCTGGCGGTGGATACTGAAGAGCTGCTGAACCTCATCCGCGG
CTTCCGCGTCTCCTCCGGCCATCAGCTGCACGGCATGGCGCGCGAGATGCGCATGGCGGGGTGA

Upstream 100 bases:

>100_bases
TTCGGCCCTTTCATCGCGCATCATGCGCCTCTCCCCTCTCCGAAACATCGGTACCGCGCGGCGTTTTTACGACGCGCGAT
CCCAAACCTTGCGAGCGCCC

Downstream 100 bases:

>100_bases
TACGCTCCGAGGCTATCAACAACGGCGCCGGGGGAAACTCCGGCGCTTTTGTTTCAACTGGTTAGCGCATCGAGCCGATC
GATATCGGCCGGGGAAAAGA

Product: methyl-accepting chemotaxis protein A

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MKNLSISRQLIVLVVALMAAFGAATFYQLKSATDAIYEERYGMLRTQVQSAISILQSFHDKEKAGTLSRDEAMKQAYATV
SAMRFTPDGYLFGYDYDVTMKFHPDTKRVGENYKGKPDSKGFAYRDELVRLGRNGGGQTDFYGPKPGMEGNDYAKSSYAL
AFEPWQVVVVTGVYIDDLNAQVRGEVMKALSIGALIFVLALAAAFYVIRGISKPLGDIHRALGEVANENVSLAIPHTGLT
NEVGMMAKATASLQDKVRERHAMQRREEEQQQQLDAERQNNLDMQRDEAALQARVVATIGEALEKLAGGDLTVRCGDLGN
RYAALRDNFNEALTHLDAAMAKVNTKSIDIGGSKDEIRKASNELSQRTERQAANLEETSAALDELTVAVRQTAEGAADAA
KRVTTVSSEATRSDRVVEEAITAMSGIEQSSDQISNIIGVIDVIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELA
QKSAAAAKEIKDQIARSSAQVENGVRLVGEAGDALKRISDQIKSANEIVSKIAHSAAEQDTTLRSISTSLNQLDVATQHN
AAMAEETTASAEALAVDTEELLNLIRGFRVSSGHQLHGMAREMRMAG

Sequences:

>Translated_607_residues
MKNLSISRQLIVLVVALMAAFGAATFYQLKSATDAIYEERYGMLRTQVQSAISILQSFHDKEKAGTLSRDEAMKQAYATV
SAMRFTPDGYLFGYDYDVTMKFHPDTKRVGENYKGKPDSKGFAYRDELVRLGRNGGGQTDFYGPKPGMEGNDYAKSSYAL
AFEPWQVVVVTGVYIDDLNAQVRGEVMKALSIGALIFVLALAAAFYVIRGISKPLGDIHRALGEVANENVSLAIPHTGLT
NEVGMMAKATASLQDKVRERHAMQRREEEQQQQLDAERQNNLDMQRDEAALQARVVATIGEALEKLAGGDLTVRCGDLGN
RYAALRDNFNEALTHLDAAMAKVNTKSIDIGGSKDEIRKASNELSQRTERQAANLEETSAALDELTVAVRQTAEGAADAA
KRVTTVSSEATRSDRVVEEAITAMSGIEQSSDQISNIIGVIDVIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELA
QKSAAAAKEIKDQIARSSAQVENGVRLVGEAGDALKRISDQIKSANEIVSKIAHSAAEQDTTLRSISTSLNQLDVATQHN
AAMAEETTASAEALAVDTEELLNLIRGFRVSSGHQLHGMAREMRMAG
>Mature_607_residues
MKNLSISRQLIVLVVALMAAFGAATFYQLKSATDAIYEERYGMLRTQVQSAISILQSFHDKEKAGTLSRDEAMKQAYATV
SAMRFTPDGYLFGYDYDVTMKFHPDTKRVGENYKGKPDSKGFAYRDELVRLGRNGGGQTDFYGPKPGMEGNDYAKSSYAL
AFEPWQVVVVTGVYIDDLNAQVRGEVMKALSIGALIFVLALAAAFYVIRGISKPLGDIHRALGEVANENVSLAIPHTGLT
NEVGMMAKATASLQDKVRERHAMQRREEEQQQQLDAERQNNLDMQRDEAALQARVVATIGEALEKLAGGDLTVRCGDLGN
RYAALRDNFNEALTHLDAAMAKVNTKSIDIGGSKDEIRKASNELSQRTERQAANLEETSAALDELTVAVRQTAEGAADAA
KRVTTVSSEATRSDRVVEEAITAMSGIEQSSDQISNIIGVIDVIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELA
QKSAAAAKEIKDQIARSSAQVENGVRLVGEAGDALKRISDQIKSANEIVSKIAHSAAEQDTTLRSISTSLNQLDVATQHN
AAMAEETTASAEALAVDTEELLNLIRGFRVSSGHQLHGMAREMRMAG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=306, Percent_Identity=38.562091503268, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1788195, Length=308, Percent_Identity=38.3116883116883, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI2367378, Length=274, Percent_Identity=40.1459854014599, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI1788194, Length=287, Percent_Identity=38.3275261324042, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789453, Length=225, Percent_Identity=37.3333333333333, Blast_Score=147, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 65600; Mature: 65600

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLSISRQLIVLVVALMAAFGAATFYQLKSATDAIYEERYGMLRTQVQSAISILQSFHD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEKAGTLSRDEAMKQAYATVSAMRFTPDGYLFGYDYDVTMKFHPDTKRVGENYKGKPDSK
HHHCCCCHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEEEEECCCHHHHCCCCCCCCCCC
GFAYRDELVRLGRNGGGQTDFYGPKPGMEGNDYAKSSYALAFEPWQVVVVTGVYIDDLNA
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEEEEECCCH
QVRGEVMKALSIGALIFVLALAAAFYVIRGISKPLGDIHRALGEVANENVSLAIPHTGLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCC
NEVGMMAKATASLQDKVRERHAMQRREEEQQQQLDAERQNNLDMQRDEAALQARVVATIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EALEKLAGGDLTVRCGDLGNRYAALRDNFNEALTHLDAAMAKVNTKSIDIGGSKDEIRKA
HHHHHHCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
SNELSQRTERQAANLEETSAALDELTVAVRQTAEGAADAAKRVTTVSSEATRSDRVVEEA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITAMSGIEQSSDQISNIIGVIDVIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHH
QKSAAAAKEIKDQIARSSAQVENGVRLVGEAGDALKRISDQIKSANEIVSKIAHSAAEQD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTLRSISTSLNQLDVATQHNAAMAEETTASAEALAVDTEELLNLIRGFRVSSGHQLHGMA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCCCCHHHHHH
REMRMAG
HHHHCCC
>Mature Secondary Structure
MKNLSISRQLIVLVVALMAAFGAATFYQLKSATDAIYEERYGMLRTQVQSAISILQSFHD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEKAGTLSRDEAMKQAYATVSAMRFTPDGYLFGYDYDVTMKFHPDTKRVGENYKGKPDSK
HHHCCCCHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEEEEECCCHHHHCCCCCCCCCCC
GFAYRDELVRLGRNGGGQTDFYGPKPGMEGNDYAKSSYALAFEPWQVVVVTGVYIDDLNA
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEEEEECCCH
QVRGEVMKALSIGALIFVLALAAAFYVIRGISKPLGDIHRALGEVANENVSLAIPHTGLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCC
NEVGMMAKATASLQDKVRERHAMQRREEEQQQQLDAERQNNLDMQRDEAALQARVVATIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EALEKLAGGDLTVRCGDLGNRYAALRDNFNEALTHLDAAMAKVNTKSIDIGGSKDEIRKA
HHHHHHCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
SNELSQRTERQAANLEETSAALDELTVAVRQTAEGAADAAKRVTTVSSEATRSDRVVEEA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITAMSGIEQSSDQISNIIGVIDVIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHH
QKSAAAAKEIKDQIARSSAQVENGVRLVGEAGDALKRISDQIKSANEIVSKIAHSAAEQD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTLRSISTSLNQLDVATQHNAAMAEETTASAEALAVDTEELLNLIRGFRVSSGHQLHGMA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCCCCHHHHHH
REMRMAG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]