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The map label for this gene is tlyC [H]

Identifier: 159184275

GI number: 159184275

Start: 352675

End: 353817

Strand: Direct

Name: tlyC [H]

Synonym: Atu0359

Alternate gene names: 159184275

Gene position: 352675-353817 (Clockwise)

Preceding gene: 159184274

Following gene: 15887711

Centisome position: 12.41

GC content: 60.28

Gene sequence:

>1143_bases
ATGAACGAACATTCTGCACGACCTGCCAATGAGGGCAGAGAAAACGGCGAGCAGTCCTCTTCGGAGGAGGGCAGTAGTCA
CTTACGGAACGACTCTCATGCAAAGCCGAGATCGACGATCTGGTCGCGCATAGGGCGGTTGCTGAAACCGTCACAGGGCG
AGCGCCTGCGTGAGGATCTGACCGACGCGCTGATGGCTGACACCGAAATCGGTGCCGCCTTTTCGCCTGAAGAGCGGGCG
ATGCTCAACAATATCCTGCGTTTCCGGGAAGTTCGGGTCGAAGATATCATGATCCCACGGGTCGATATCGACGGTCTCGA
CCAGAACATGACGATCGGCGAAGCGCTGATCCTGTTTGAAGAAACCGGGCGCTCCCGCATGCCTGTTTACGATGAGACGC
TGGATAATCCCAAGGGCATGATCCATATCCGCGATCTGCTGGCCTATGTCGCCAAGCAGGCCCGTAACAAACGCCGCGCG
GGTTCGCGCAGCGTCGCTTATGGCGAGGTGAAGGCAACAACGCGCTCACCACGTCCGAATTTCGATCTGGCGCGGGTCGA
TCTCGAGCAGACGGTCGCCGATGCCGGCCTCGTGCGCAAAATTCTCTTCGCACCACCCTCGATGCTTGCCTCCGACCTCT
TGAAGACGATGCAGGCACAGAGAACGCAGCTGGCCCTGGTCATCGACGAATATGGCGGCACGGACGGTCTCGTCAGCCAC
GAGGATATCGTCGAGATGGTCGTGGGCGATATCGATGACGAGCACGACAAGGACGAGGCGATGTTTTCGCGTCTCTCCGC
CGATGTGCTTGTCGCGGATGCCCGCGCGGAACTCACCGAACTTGCCGAGGTGATCGGGCCCGAATTCGACGTGCGCGAAC
ATCTGGAAGAAATCGATACGCTCGGCGGCCTCATCTTTTTCGCGCTCGGCCGCATTCCGGCCAAGGGCGAGGTGGTCAGG
GCTGTGCCCGGTTTCGAGTTTCAGATTCTCGACGCGGATAGCCGGCGTATCAAGGGCGTCCGTATCGTTCGTGATCATGG
CTCGGAAGGGCAGGACGACCAGGCTCCCGGCGAAGCCGACGGGGTTATCGCACTGCCCGCGCCCGATGTTCGCCTGATCA
CGCACCAGCAGAACGCCGACTAG

Upstream 100 bases:

>100_bases
AGCGGAAGAAATGGAGTCGCTTGAGACTCGCATTTTGGCGGTGCTTGGCCTATCTGATCCCTACGCGGGTCAGGAGCCGC
TTTAAATATTGTCTGGAGCC

Downstream 100 bases:

>100_bases
AAAAGGTGACAGGGGAGCCCCCGTCACCTTTATCTCAAGACGGAGATTCGGCAGGTTGGAACGACCAAAAGGCCGCAGGA
GACCGCCGCCGCGATCCCAC

Product: hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNEHSARPANEGRENGEQSSSEEGSSHLRNDSHAKPRSTIWSRIGRLLKPSQGERLREDLTDALMADTEIGAAFSPEERA
MLNNILRFREVRVEDIMIPRVDIDGLDQNMTIGEALILFEETGRSRMPVYDETLDNPKGMIHIRDLLAYVAKQARNKRRA
GSRSVAYGEVKATTRSPRPNFDLARVDLEQTVADAGLVRKILFAPPSMLASDLLKTMQAQRTQLALVIDEYGGTDGLVSH
EDIVEMVVGDIDDEHDKDEAMFSRLSADVLVADARAELTELAEVIGPEFDVREHLEEIDTLGGLIFFALGRIPAKGEVVR
AVPGFEFQILDADSRRIKGVRIVRDHGSEGQDDQAPGEADGVIALPAPDVRLITHQQNAD

Sequences:

>Translated_380_residues
MNEHSARPANEGRENGEQSSSEEGSSHLRNDSHAKPRSTIWSRIGRLLKPSQGERLREDLTDALMADTEIGAAFSPEERA
MLNNILRFREVRVEDIMIPRVDIDGLDQNMTIGEALILFEETGRSRMPVYDETLDNPKGMIHIRDLLAYVAKQARNKRRA
GSRSVAYGEVKATTRSPRPNFDLARVDLEQTVADAGLVRKILFAPPSMLASDLLKTMQAQRTQLALVIDEYGGTDGLVSH
EDIVEMVVGDIDDEHDKDEAMFSRLSADVLVADARAELTELAEVIGPEFDVREHLEEIDTLGGLIFFALGRIPAKGEVVR
AVPGFEFQILDADSRRIKGVRIVRDHGSEGQDDQAPGEADGVIALPAPDVRLITHQQNAD
>Mature_380_residues
MNEHSARPANEGRENGEQSSSEEGSSHLRNDSHAKPRSTIWSRIGRLLKPSQGERLREDLTDALMADTEIGAAFSPEERA
MLNNILRFREVRVEDIMIPRVDIDGLDQNMTIGEALILFEETGRSRMPVYDETLDNPKGMIHIRDLLAYVAKQARNKRRA
GSRSVAYGEVKATTRSPRPNFDLARVDLEQTVADAGLVRKILFAPPSMLASDLLKTMQAQRTQLALVIDEYGGTDGLVSH
EDIVEMVVGDIDDEHDKDEAMFSRLSADVLVADARAELTELAEVIGPEFDVREHLEEIDTLGGLIFFALGRIPAKGEVVR
AVPGFEFQILDADSRRIKGVRIVRDHGSEGQDDQAPGEADGVIALPAPDVRLITHQQNAD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=257, Percent_Identity=26.8482490272374, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786879, Length=292, Percent_Identity=31.5068493150685, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 42063; Mature: 42063

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEHSARPANEGRENGEQSSSEEGSSHLRNDSHAKPRSTIWSRIGRLLKPSQGERLREDL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
TDALMADTEIGAAFSPEERAMLNNILRFREVRVEDIMIPRVDIDGLDQNMTIGEALILFE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHEEEEEE
ETGRSRMPVYDETLDNPKGMIHIRDLLAYVAKQARNKRRAGSRSVAYGEVKATTRSPRPN
CCCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEECEEEECCCCCCCC
FDLARVDLEQTVADAGLVRKILFAPPSMLASDLLKTMQAQRTQLALVIDEYGGTDGLVSH
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCH
EDIVEMVVGDIDDEHDKDEAMFSRLSADVLVADARAELTELAEVIGPEFDVREHLEEIDT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEECHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGGLIFFALGRIPAKGEVVRAVPGFEFQILDADSRRIKGVRIVRDHGSEGQDDQAPGEAD
HHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCC
GVIALPAPDVRLITHQQNAD
CEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MNEHSARPANEGRENGEQSSSEEGSSHLRNDSHAKPRSTIWSRIGRLLKPSQGERLREDL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
TDALMADTEIGAAFSPEERAMLNNILRFREVRVEDIMIPRVDIDGLDQNMTIGEALILFE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHEEEEEE
ETGRSRMPVYDETLDNPKGMIHIRDLLAYVAKQARNKRRAGSRSVAYGEVKATTRSPRPN
CCCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEECEEEECCCCCCCC
FDLARVDLEQTVADAGLVRKILFAPPSMLASDLLKTMQAQRTQLALVIDEYGGTDGLVSH
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCH
EDIVEMVVGDIDDEHDKDEAMFSRLSADVLVADARAELTELAEVIGPEFDVREHLEEIDT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEECHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGGLIFFALGRIPAKGEVVRAVPGFEFQILDADSRRIKGVRIVRDHGSEGQDDQAPGEAD
HHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCC
GVIALPAPDVRLITHQQNAD
CEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA