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The map label for this gene is lnt

Identifier: 15887711

GI number: 15887711

Start: 354024

End: 355613

Strand: Direct

Name: lnt

Synonym: Atu0360

Alternate gene names: 15887711

Gene position: 354024-355613 (Clockwise)

Preceding gene: 159184275

Following gene: 159184276

Centisome position: 12.46

GC content: 59.81

Gene sequence:

>1590_bases
ATGGAGCGTCTTGCAGGCAGGGTAATGCTGGCCGGCGGCATGAGCCGCGCAGTGATGGCGATTGCTGCGGGTGCTGTCGG
GGCGCTCGCTTTGCCTCCATTCGGCTTTTTCGCAGCGCTTTTTTTCTCTTTCACCTTGCTTGTCTGGCTCGTGGACGGCT
GCACCGGCAAGCCGGGTGGTGGTCTCTTCAGCCGCATTCTGCCGGCTTTCGGCATCGGCTGGTGTTTCGGGTTTGGTTAT
TTCGTGGCAGGCCTGTGGTGGCTGGGCAATGCTCTTCTACTGGAAGCGGATGAATTCGCCTGGGCCTTGCCGCTCGCCAT
CCTCGGTCTGCCGGCACTGCTGGCGCTGTTTTACGGTTTTGCCGTCGCGGCCGCCAATCTCCTCTGGTCGGACGGCCTTG
GTCGCATTGCGGCGCTTGCCGCCGCCTTCGGCGTTTCGGAATGGTTGCGCAGTTTCCTCGCGACCGGCTTTCCCTGGAAC
GCCATCGGCTATGGCATCATGCCCATCCCGATCATGATGCAGTCTGCGCACTTGCTCGGTCTTCTCAGCATCACGACGCT
GGCGGTTTTCATTTTCGCTTCACCAGCGCTGATCGGTACGAAAAAAGGCATGGGACCAGGACTGGCGCTGGCAGGCCTAT
TGCTTGCGGCCCACTTCGGTTATGGCTTTTACCGCCTGCAGACACCAGCGGAGACGCCGGCAGACGCCCTGACCGTCCGC
ATCGTGCAGCCGGCCATCGATCAATCCCGCAAGATGCTGAATACTGACCGTGCCGAGATTTTCGCAGAGCACCTGCGGTT
GTCGGCCCTGCCGCCGGGCGAAGGGAAAAAACGCCCCGACATCATCGTCTGGCCGGAAACCTCCGTGCCGTTCATCCTGA
CGCAAAATCCGGATGCGCTCGCGGAAATCGCCAGTACGCTCGAGGATGGCCAGGTGCTGTTCACCGGCGCCGTCAGGATG
GAAGATCAGGGAGCCGGCCGGCCGCCCCGTTATTACAATTCGGTCTATGCGATCGACAGCCAGGGCGAGATCATCGGCGC
GACCGACAAGGTGCATCTGACGCCCTTTGGCGAATACGTTCCCTTTGAAGGCATCCTGCGGGAATTCGGCATCGACAATG
TCATTGCCCTGCCGGGTGGCTTTTCCGCCGCCTCGTCGCGCACGCCGCTCACGCTCCCTTCAGGCAAGACTTTCTATCCC
CTGATCTGTTACGAGATCATTTTCCCGGGTGAGATGACGCCGGGCCTTCAGGGGGCGGCGGCGATCCTAAATGTGACGAA
TGACGGCTGGTTTGGTGATACACCCGGTCCCTACCAGCATTTTCTGCAGGCACGGGTACGCGCCGTTGAGACGGGCGTGC
CGGTGATTCGCGGCGCCAATACCGGAATTTCCGCCGTCATAGACCCCTATGGCCGCATTATTGCCGGGCTGGACTATGGT
CGGGTGGGAATTCTTGACGCCACTTTGAGTGGTGGGTCTAATGACGCATTTACTTACGACACACATCGGACGTATTTCTG
GTTGATTTTTTCAATCTTGATGATCGTTGCGGTATTTCCCGCCTTGAGTTTTGCTCGGCGCCAGAATTGA

Upstream 100 bases:

>100_bases
ACTGCGAATCTTTTTTCCTTTACGCCGGGTTTGAGGGGAAATTCCGTGGCGCGGCCTTGCCGGGAGCGGGCTTTTCCAGA
CGCGCATAAACGGAGATGGC

Downstream 100 bases:

>100_bases
CCGGGAACCCCTGTAATTGCATAGTGAATACGTCAGTCGTAAAACAAGTTTAGACGCTGTCGAATTGCCGACTCATTTCT
TCGAATAGTAGTGAAACGAG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MERLAGRVMLAGGMSRAVMAIAAGAVGALALPPFGFFAALFFSFTLLVWLVDGCTGKPGGGLFSRILPAFGIGWCFGFGY
FVAGLWWLGNALLLEADEFAWALPLAILGLPALLALFYGFAVAAANLLWSDGLGRIAALAAAFGVSEWLRSFLATGFPWN
AIGYGIMPIPIMMQSAHLLGLLSITTLAVFIFASPALIGTKKGMGPGLALAGLLLAAHFGYGFYRLQTPAETPADALTVR
IVQPAIDQSRKMLNTDRAEIFAEHLRLSALPPGEGKKRPDIIVWPETSVPFILTQNPDALAEIASTLEDGQVLFTGAVRM
EDQGAGRPPRYYNSVYAIDSQGEIIGATDKVHLTPFGEYVPFEGILREFGIDNVIALPGGFSAASSRTPLTLPSGKTFYP
LICYEIIFPGEMTPGLQGAAAILNVTNDGWFGDTPGPYQHFLQARVRAVETGVPVIRGANTGISAVIDPYGRIIAGLDYG
RVGILDATLSGGSNDAFTYDTHRTYFWLIFSILMIVAVFPALSFARRQN

Sequences:

>Translated_529_residues
MERLAGRVMLAGGMSRAVMAIAAGAVGALALPPFGFFAALFFSFTLLVWLVDGCTGKPGGGLFSRILPAFGIGWCFGFGY
FVAGLWWLGNALLLEADEFAWALPLAILGLPALLALFYGFAVAAANLLWSDGLGRIAALAAAFGVSEWLRSFLATGFPWN
AIGYGIMPIPIMMQSAHLLGLLSITTLAVFIFASPALIGTKKGMGPGLALAGLLLAAHFGYGFYRLQTPAETPADALTVR
IVQPAIDQSRKMLNTDRAEIFAEHLRLSALPPGEGKKRPDIIVWPETSVPFILTQNPDALAEIASTLEDGQVLFTGAVRM
EDQGAGRPPRYYNSVYAIDSQGEIIGATDKVHLTPFGEYVPFEGILREFGIDNVIALPGGFSAASSRTPLTLPSGKTFYP
LICYEIIFPGEMTPGLQGAAAILNVTNDGWFGDTPGPYQHFLQARVRAVETGVPVIRGANTGISAVIDPYGRIIAGLDYG
RVGILDATLSGGSNDAFTYDTHRTYFWLIFSILMIVAVFPALSFARRQN
>Mature_529_residues
MERLAGRVMLAGGMSRAVMAIAAGAVGALALPPFGFFAALFFSFTLLVWLVDGCTGKPGGGLFSRILPAFGIGWCFGFGY
FVAGLWWLGNALLLEADEFAWALPLAILGLPALLALFYGFAVAAANLLWSDGLGRIAALAAAFGVSEWLRSFLATGFPWN
AIGYGIMPIPIMMQSAHLLGLLSITTLAVFIFASPALIGTKKGMGPGLALAGLLLAAHFGYGFYRLQTPAETPADALTVR
IVQPAIDQSRKMLNTDRAEIFAEHLRLSALPPGEGKKRPDIIVWPETSVPFILTQNPDALAEIASTLEDGQVLFTGAVRM
EDQGAGRPPRYYNSVYAIDSQGEIIGATDKVHLTPFGEYVPFEGILREFGIDNVIALPGGFSAASSRTPLTLPSGKTFYP
LICYEIIFPGEMTPGLQGAAAILNVTNDGWFGDTPGPYQHFLQARVRAVETGVPVIRGANTGISAVIDPYGRIIAGLDYG
RVGILDATLSGGSNDAFTYDTHRTYFWLIFSILMIVAVFPALSFARRQN

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=524, Percent_Identity=28.6259541984733, Blast_Score=155, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_AGRT5 (Q8UID7)

Other databases:

- EMBL:   AE007869
- PIR:   AH2620
- PIR:   H97402
- RefSeq:   NP_353392.1
- ProteinModelPortal:   Q8UID7
- STRING:   Q8UID7
- GeneID:   1132398
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0360
- eggNOG:   COG0815
- HOGENOM:   HBG616234
- OMA:   MPPGRRI
- PhylomeDB:   Q8UID7
- ProtClustDB:   PRK00302
- BioCyc:   ATUM176299-1:ATU0360-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 56501; Mature: 56501

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcdc5e38)-; HASH(0xc48ce90)-; HASH(0x404e4ca4)-; HASH(0x4051480c)-; HASH(0xb2e8ffc)-; HASH(0xc787f5c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLAGRVMLAGGMSRAVMAIAAGAVGALALPPFGFFAALFFSFTLLVWLVDGCTGKPGG
CCCHHCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GLFSRILPAFGIGWCFGFGYFVAGLWWLGNALLLEADEFAWALPLAILGLPALLALFYGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
AVAAANLLWSDGLGRIAALAAAFGVSEWLRSFLATGFPWNAIGYGIMPIPIMMQSAHLLG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHH
LLSITTLAVFIFASPALIGTKKGMGPGLALAGLLLAAHFGYGFYRLQTPAETPADALTVR
HHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHEEEE
IVQPAIDQSRKMLNTDRAEIFAEHLRLSALPPGEGKKRPDIIVWPETSVPFILTQNPDAL
EEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCEEEECCCHHH
AEIASTLEDGQVLFTGAVRMEDQGAGRPPRYYNSVYAIDSQGEIIGATDKVHLTPFGEYV
HHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCEEECCCEEEECCCCCCC
PFEGILREFGIDNVIALPGGFSAASSRTPLTLPSGKTFYPLICYEIIFPGEMTPGLQGAA
CHHHHHHHCCCCCEEECCCCCCCCCCCCCEECCCCCCCHHEEEEEEEECCCCCCCCCCCE
AILNVTNDGWFGDTPGPYQHFLQARVRAVETGVPVIRGANTGISAVIDPYGRIIAGLDYG
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHCCHHHHHCCCCCC
RVGILDATLSGGSNDAFTYDTHRTYFWLIFSILMIVAVFPALSFARRQN
CEEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MERLAGRVMLAGGMSRAVMAIAAGAVGALALPPFGFFAALFFSFTLLVWLVDGCTGKPGG
CCCHHCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GLFSRILPAFGIGWCFGFGYFVAGLWWLGNALLLEADEFAWALPLAILGLPALLALFYGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
AVAAANLLWSDGLGRIAALAAAFGVSEWLRSFLATGFPWNAIGYGIMPIPIMMQSAHLLG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHH
LLSITTLAVFIFASPALIGTKKGMGPGLALAGLLLAAHFGYGFYRLQTPAETPADALTVR
HHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHEEEE
IVQPAIDQSRKMLNTDRAEIFAEHLRLSALPPGEGKKRPDIIVWPETSVPFILTQNPDAL
EEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCEEEECCCHHH
AEIASTLEDGQVLFTGAVRMEDQGAGRPPRYYNSVYAIDSQGEIIGATDKVHLTPFGEYV
HHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCEEECCCEEEECCCCCCC
PFEGILREFGIDNVIALPGGFSAASSRTPLTLPSGKTFYPLICYEIIFPGEMTPGLQGAA
CHHHHHHHCCCCCEEECCCCCCCCCCCCCEECCCCCCCHHEEEEEEEECCCCCCCCCCCE
AILNVTNDGWFGDTPGPYQHFLQARVRAVETGVPVIRGANTGISAVIDPYGRIIAGLDYG
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHCCHHHHHCCCCCC
RVGILDATLSGGSNDAFTYDTHRTYFWLIFSILMIVAVFPALSFARRQN
CEEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194