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The map label for this gene is coaD

Identifier: 15888987

GI number: 15888987

Start: 1668170

End: 1668664

Strand: Reverse

Name: coaD

Synonym: Atu1681

Alternate gene names: 15888987

Gene position: 1668664-1668170 (Counterclockwise)

Preceding gene: 15888998

Following gene: 15888986

Centisome position: 58.72

GC content: 60.4

Gene sequence:

>495_bases
ATGACGATTGCCTTTTATCCAGGATCATTCGATCCGATGACCAACGGACATCTGGATGTGCTTATCCAGGCGCTGAACGT
GGCGTCGAAAGTCATCGTCGCCGTTGGCATCCATCCCGGAAAAGCACCGCTGTTCAGCTTCGACGAGCGGGCGGCACTGA
TAAGCCGGGCGCTTTCCGAAACCCTGCCGGGCGAGGCGGCACGCGTGGAAGTCGTGTCCTTCGACAATCTGGTTGTCGAT
GCCGCCCGCCAGCATGGCGCGCATCTTTTGCTGCGCGGCCTTCGCGATGGCACCGATCTCGATTATGAAATGCAGATGGC
CGGCATGAACCGCCAGATGGCGCCTGATATTCAGACCGTGTTCCTGCCCGCCGGCACCTCGTCGCGACCCATTACAGCCA
CATTGGTCCGGCAGATCGCCGCCATGGGCGGCAATGTCGATGCCTTCGTGCCGAAAGCCGTGCTTGAAGCCCTCAACGCC
AAGCTGAAGCGCTGA

Upstream 100 bases:

>100_bases
TGGCGCGTGGTTATAAAGTCTTGCGCCGCGTGGCTCTCCATGACAAAAGGCGGGCACATGAATATCCAGCATCGAAGCGC
GCCCACCATCTGAGAGCGAT

Downstream 100 bases:

>100_bases
CTTCAGCCTTACATTCTGGAGCCAATCCGATGAAACTCGTTCGATTTGCCTTTGCCGGCGCCCTGTTTGCCGGCGCGCTT
GCCGCCAGCACTTTTGCTTC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTIAFYPGSFDPMTNGHLDVLIQALNVASKVIVAVGIHPGKAPLFSFDERAALISRALSETLPGEAARVEVVSFDNLVVD
AARQHGAHLLLRGLRDGTDLDYEMQMAGMNRQMAPDIQTVFLPAGTSSRPITATLVRQIAAMGGNVDAFVPKAVLEALNA
KLKR

Sequences:

>Translated_164_residues
MTIAFYPGSFDPMTNGHLDVLIQALNVASKVIVAVGIHPGKAPLFSFDERAALISRALSETLPGEAARVEVVSFDNLVVD
AARQHGAHLLLRGLRDGTDLDYEMQMAGMNRQMAPDIQTVFLPAGTSSRPITATLVRQIAAMGGNVDAFVPKAVLEALNA
KLKR
>Mature_163_residues
TIAFYPGSFDPMTNGHLDVLIQALNVASKVIVAVGIHPGKAPLFSFDERAALISRALSETLPGEAARVEVVSFDNLVVDA
ARQHGAHLLLRGLRDGTDLDYEMQMAGMNRQMAPDIQTVFLPAGTSSRPITATLVRQIAAMGGNVDAFVPKAVLEALNAK
LKR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=41.5094339622642, Blast_Score=134, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_AGRT5 (Q8UES4)

Other databases:

- EMBL:   AE007869
- PIR:   AC2783
- PIR:   D97562
- RefSeq:   NP_354668.1
- ProteinModelPortal:   Q8UES4
- SMR:   Q8UES4
- STRING:   Q8UES4
- GeneID:   1133719
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1681
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   ATUM176299-1:ATU1681-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17552; Mature: 17420

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAFYPGSFDPMTNGHLDVLIQALNVASKVIVAVGIHPGKAPLFSFDERAALISRALSE
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
TLPGEAARVEVVSFDNLVVDAARQHGAHLLLRGLRDGTDLDYEMQMAGMNRQMAPDIQTV
HCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEE
FLPAGTSSRPITATLVRQIAAMGGNVDAFVPKAVLEALNAKLKR
EEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIAFYPGSFDPMTNGHLDVLIQALNVASKVIVAVGIHPGKAPLFSFDERAALISRALSE
EEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
TLPGEAARVEVVSFDNLVVDAARQHGAHLLLRGLRDGTDLDYEMQMAGMNRQMAPDIQTV
HCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEE
FLPAGTSSRPITATLVRQIAAMGGNVDAFVPKAVLEALNAKLKR
EEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194