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The map label for this gene is ppiB [H]

Identifier: 15888985

GI number: 15888985

Start: 1667025

End: 1667534

Strand: Reverse

Name: ppiB [H]

Synonym: Atu1679

Alternate gene names: 15888985

Gene position: 1667534-1667025 (Counterclockwise)

Preceding gene: 15888986

Following gene: 159184871

Centisome position: 58.68

GC content: 59.22

Gene sequence:

>510_bases
ATGACCGAGATCAAGGATCCGGAAAACACCATCATCATGGAAACGACGACCGGTAAGGTCGTGATCCAGCTGCTTCCGGA
AGTTGCGCCGGGCCACGTTGCCCGCATTAAGGAATTGGTATCGGAAGGCGCTTATGACGGCGTCGTGTTCCACCGCGTCA
TCGAAGACTTCATGGCCCAGACGGGCGACGTGAAGTTCGGCAAGAAGGGTTCTGAGAGCTTCAACCCGGCCCGCGCCGGC
ATGGGCGGCTCCGAGAAGGAAGACCTGAAGGCGGAATTCTCCGCCATTCCGCACGTTCGCGGCACCTGCTCCATGGCCCG
TTCGCAGAGCCCGAACTCCGCCAACTCGCAGTTCTTCATCTGCTTCACGGATTCCCCGTGGCTGAACAAGCAGTACACGG
TCTGGGGCCAGGTCATCGAAGGCATGGAAGCCATCGACAAGATCAAGCGCGGCGAGCCGGTGAAGGATCCCGATTCGATC
GTTTCCATCAAGCTTGCTTCTGCGGCTTGA

Upstream 100 bases:

>100_bases
CGGCGGCAACGGCGAAGTTTCCAACCCCGACCGGATGATCAAGGTCACCGTCGGCAAGAAGTAAGGTAGGGCAATAGAGC
CCGAAAAGAGGAGAATAACC

Downstream 100 bases:

>100_bases
GAATAGCGTATAACGTATTTACCCGCTCCGCAGGAAACTGCGGGGCGTTTCACATTGGTGACAAGGGTGCCAACCTCTCA
GGCGTCATCCTCGGGCTTGT

Product: peptidyl prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MTEIKDPENTIIMETTTGKVVIQLLPEVAPGHVARIKELVSEGAYDGVVFHRVIEDFMAQTGDVKFGKKGSESFNPARAG
MGGSEKEDLKAEFSAIPHVRGTCSMARSQSPNSANSQFFICFTDSPWLNKQYTVWGQVIEGMEAIDKIKRGEPVKDPDSI
VSIKLASAA

Sequences:

>Translated_169_residues
MTEIKDPENTIIMETTTGKVVIQLLPEVAPGHVARIKELVSEGAYDGVVFHRVIEDFMAQTGDVKFGKKGSESFNPARAG
MGGSEKEDLKAEFSAIPHVRGTCSMARSQSPNSANSQFFICFTDSPWLNKQYTVWGQVIEGMEAIDKIKRGEPVKDPDSI
VSIKLASAA
>Mature_168_residues
TEIKDPENTIIMETTTGKVVIQLLPEVAPGHVARIKELVSEGAYDGVVFHRVIEDFMAQTGDVKFGKKGSESFNPARAGM
GGSEKEDLKAEFSAIPHVRGTCSMARSQSPNSANSQFFICFTDSPWLNKQYTVWGQVIEGMEAIDKIKRGEPVKDPDSIV
SIKLASAA

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI19557636, Length=158, Percent_Identity=33.5443037974684, Blast_Score=87, Evalue=5e-18,
Organism=Homo sapiens, GI24308049, Length=147, Percent_Identity=37.4149659863946, Blast_Score=81, Evalue=4e-16,
Organism=Homo sapiens, GI7706339, Length=146, Percent_Identity=30.1369863013699, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI5031987, Length=137, Percent_Identity=35.036496350365, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI22547215, Length=136, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI22547212, Length=136, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI7657473, Length=136, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI4505991, Length=148, Percent_Identity=33.7837837837838, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786736, Length=148, Percent_Identity=34.4594594594595, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1789763, Length=150, Percent_Identity=30.6666666666667, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71980594, Length=142, Percent_Identity=37.3239436619718, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71980590, Length=142, Percent_Identity=37.3239436619718, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17539496, Length=147, Percent_Identity=31.9727891156463, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17506311, Length=145, Percent_Identity=33.1034482758621, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565860, Length=164, Percent_Identity=31.0975609756098, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17539498, Length=153, Percent_Identity=32.0261437908497, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17552780, Length=137, Percent_Identity=36.4963503649635, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559074, Length=156, Percent_Identity=29.4871794871795, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32563659, Length=142, Percent_Identity=32.3943661971831, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17506307, Length=143, Percent_Identity=32.8671328671329, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17566266, Length=144, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322492, Length=175, Percent_Identity=29.7142857142857, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320359, Length=137, Percent_Identity=33.5766423357664, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323562, Length=143, Percent_Identity=32.1678321678322, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17986117, Length=183, Percent_Identity=31.1475409836066, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19922912, Length=166, Percent_Identity=35.5421686746988, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17647301, Length=136, Percent_Identity=33.8235294117647, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24652460, Length=145, Percent_Identity=31.7241379310345, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45549139, Length=138, Percent_Identity=31.8840579710145, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 18420; Mature: 18289

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIKDPENTIIMETTTGKVVIQLLPEVAPGHVARIKELVSEGAYDGVVFHRVIEDFMAQ
CCCCCCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TGDVKFGKKGSESFNPARAGMGGSEKEDLKAEFSAIPHVRGTCSMARSQSPNSANSQFFI
CCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEE
CFTDSPWLNKQYTVWGQVIEGMEAIDKIKRGEPVKDPDSIVSIKLASAA
EECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
TEIKDPENTIIMETTTGKVVIQLLPEVAPGHVARIKELVSEGAYDGVVFHRVIEDFMAQ
CCCCCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TGDVKFGKKGSESFNPARAGMGGSEKEDLKAEFSAIPHVRGTCSMARSQSPNSANSQFFI
CCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEE
CFTDSPWLNKQYTVWGQVIEGMEAIDKIKRGEPVKDPDSIVSIKLASAA
EECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA