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The map label for this gene is cox15 [H]

Identifier: 15888573

GI number: 15888573

Start: 1231979

End: 1233097

Strand: Direct

Name: cox15 [H]

Synonym: Atu1242

Alternate gene names: 15888573

Gene position: 1231979-1233097 (Clockwise)

Preceding gene: 15888570

Following gene: 15888580

Centisome position: 43.36

GC content: 61.13

Gene sequence:

>1119_bases
ATGCGTTCGAACGGCATGACGATGGCAAATGGTTCTGTGGACATGGTGGTGGAGGCCGCCCTGCAGAAACAGGAAAAGGA
CCGCCGCCTGCTGCGCATCTGGCTGCGCGTCGTGCTTTTCACGCTGTTCTGTCTGGTCCTCGTCGGCGGCGCCACGCGGC
TCACCGAATCCGGCCTGTCGATCACGGAATGGAAGCCGATCCACGGCGCCATTCCGCCACTTTCCGTGGCTGAGTGGGAA
GAGGAATTCCAGCTCTACAAGCGCATTCCCCAATATCAGGAAATCAACAAGGGCATGTCGCTTGATGAGTTCAAGACGAT
TTTCTGGTGGGAATGGGCCCATCGCCTGCTCGCCCGCACCATTGGCCTCGTCTTCGCCCTGCCGCTTGCCTTCTTCTGGC
TCACCGGCCGGGTCGAAAAGCGCCTGCGCCTGCCGCTCGTCGGCCTTCTGGCGCTTGGCGGTTTTCAGGGCTTCGTCGGC
TGGTGGATGGTGTCATCAGGCCTCGTCAACCGCACGGATGTTTCGCAATATCGCCTCGCCACCCATTTGACGATCGCCTG
CCTCATCTTCGCGGGCTGCATGTGGATATTGCGAGGCCTGTCGCATCATTCGCCTGATGCGGCGGATGAGCGGACTGGCA
GGGGCTTTGCCGCGCTGCTGACGGTGCTCTGTCTGTTCCAGATCTATCTCGGCGCACTGGTGGCGGGGCTGAATGCCGGC
CTTTCCTATAATACCTGGCCGCTGATGGATGGTTCGCTGGTGCCGGGTGATCTCTTCCTGCAACAGCCCTGGTGGATAAA
CCTGTTCGAAAACCCGAAGACGGTGCAATTCGTCCATCGCCTGGGTGCCTACACGCTGTTTGCCGCCACGCTGTGGCATA
TGGTGTCGATGGCCCGCGCCTTGCCCGGCACGCCACATGCCCGCCGCGCGGTCCTGTTCTTTGTGCTCATCTCCGTTCAG
GCGGGGCTAGGCATCACCACGCTGCTGATGCATGTCGATATCCATGTGGCGCTCGCCCATCAGGGCATGGCACTGATCCT
GCTCGGCTTTTCGGTCGCCCATTGGCGCGGTTTCATCGGTGAATATCCGGCGCCCGTTGCTGTCGAAGTCAGGGACTGA

Upstream 100 bases:

>100_bases
GCGACTATAGCGCCGCGACCCCATGCCGCAAACCCTGAGGCCTTGTTTTGTAGTGCCGGTTGAGGCTAATCAACATGACT
GTATGAGGGAGACCTGAAAG

Downstream 100 bases:

>100_bases
CCCCGCTCAAAAATGTTTCAGGACTGCCTTGATGGTTGCCGCGACGGCGAGTTCGTTGTCGCGTTCTTCCGCATTGCCGT
CCTCTTCGTGCCACGTGGCC

Product: cytochrome oxidase assembly factor

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRSNGMTMANGSVDMVVEAALQKQEKDRRLLRIWLRVVLFTLFCLVLVGGATRLTESGLSITEWKPIHGAIPPLSVAEWE
EEFQLYKRIPQYQEINKGMSLDEFKTIFWWEWAHRLLARTIGLVFALPLAFFWLTGRVEKRLRLPLVGLLALGGFQGFVG
WWMVSSGLVNRTDVSQYRLATHLTIACLIFAGCMWILRGLSHHSPDAADERTGRGFAALLTVLCLFQIYLGALVAGLNAG
LSYNTWPLMDGSLVPGDLFLQQPWWINLFENPKTVQFVHRLGAYTLFAATLWHMVSMARALPGTPHARRAVLFFVLISVQ
AGLGITTLLMHVDIHVALAHQGMALILLGFSVAHWRGFIGEYPAPVAVEVRD

Sequences:

>Translated_372_residues
MRSNGMTMANGSVDMVVEAALQKQEKDRRLLRIWLRVVLFTLFCLVLVGGATRLTESGLSITEWKPIHGAIPPLSVAEWE
EEFQLYKRIPQYQEINKGMSLDEFKTIFWWEWAHRLLARTIGLVFALPLAFFWLTGRVEKRLRLPLVGLLALGGFQGFVG
WWMVSSGLVNRTDVSQYRLATHLTIACLIFAGCMWILRGLSHHSPDAADERTGRGFAALLTVLCLFQIYLGALVAGLNAG
LSYNTWPLMDGSLVPGDLFLQQPWWINLFENPKTVQFVHRLGAYTLFAATLWHMVSMARALPGTPHARRAVLFFVLISVQ
AGLGITTLLMHVDIHVALAHQGMALILLGFSVAHWRGFIGEYPAPVAVEVRD
>Mature_372_residues
MRSNGMTMANGSVDMVVEAALQKQEKDRRLLRIWLRVVLFTLFCLVLVGGATRLTESGLSITEWKPIHGAIPPLSVAEWE
EEFQLYKRIPQYQEINKGMSLDEFKTIFWWEWAHRLLARTIGLVFALPLAFFWLTGRVEKRLRLPLVGLLALGGFQGFVG
WWMVSSGLVNRTDVSQYRLATHLTIACLIFAGCMWILRGLSHHSPDAADERTGRGFAALLTVLCLFQIYLGALVAGLNAG
LSYNTWPLMDGSLVPGDLFLQQPWWINLFENPKTVQFVHRLGAYTLFAATLWHMVSMARALPGTPHARRAVLFFVLISVQ
AGLGITTLLMHVDIHVALAHQGMALILLGFSVAHWRGFIGEYPAPVAVEVRD

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [H]

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921985, Length=360, Percent_Identity=39.7222222222222, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI17921987, Length=310, Percent_Identity=39.3548387096774, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17536069, Length=345, Percent_Identity=38.8405797101449, Blast_Score=206, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320989, Length=369, Percent_Identity=39.0243902439024, Blast_Score=202, Evalue=6e-53,
Organism=Drosophila melanogaster, GI19922860, Length=360, Percent_Identity=37.2222222222222, Blast_Score=194, Evalue=9e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003780 [H]

Pfam domain/function: PF02628 COX15-CtaA [H]

EC number: NA

Molecular weight: Translated: 41737; Mature: 41737

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSNGMTMANGSVDMVVEAALQKQEKDRRLLRIWLRVVLFTLFCLVLVGGATRLTESGLS
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
ITEWKPIHGAIPPLSVAEWEEEFQLYKRIPQYQEINKGMSLDEFKTIFWWEWAHRLLART
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IGLVFALPLAFFWLTGRVEKRLRLPLVGLLALGGFQGFVGWWMVSSGLVNRTDVSQYRLA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHH
THLTIACLIFAGCMWILRGLSHHSPDAADERTGRGFAALLTVLCLFQIYLGALVAGLNAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LSYNTWPLMDGSLVPGDLFLQQPWWINLFENPKTVQFVHRLGAYTLFAATLWHMVSMARA
CCCCCCCCCCCCCCCCHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPGTPHARRAVLFFVLISVQAGLGITTLLMHVDIHVALAHQGMALILLGFSVAHWRGFIG
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHC
EYPAPVAVEVRD
CCCCCEEEEECC
>Mature Secondary Structure
MRSNGMTMANGSVDMVVEAALQKQEKDRRLLRIWLRVVLFTLFCLVLVGGATRLTESGLS
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
ITEWKPIHGAIPPLSVAEWEEEFQLYKRIPQYQEINKGMSLDEFKTIFWWEWAHRLLART
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IGLVFALPLAFFWLTGRVEKRLRLPLVGLLALGGFQGFVGWWMVSSGLVNRTDVSQYRLA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHH
THLTIACLIFAGCMWILRGLSHHSPDAADERTGRGFAALLTVLCLFQIYLGALVAGLNAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LSYNTWPLMDGSLVPGDLFLQQPWWINLFENPKTVQFVHRLGAYTLFAATLWHMVSMARA
CCCCCCCCCCCCCCCCHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPGTPHARRAVLFFVLISVQAGLGITTLLMHVDIHVALAHQGMALILLGFSVAHWRGFIG
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHC
EYPAPVAVEVRD
CCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743194; 11743193 [H]