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The map label for this gene is acpS

Identifier: 15888375

GI number: 15888375

Start: 1026081

End: 1026485

Strand: Direct

Name: acpS

Synonym: Atu1033

Alternate gene names: 15888375

Gene position: 1026081-1026485 (Clockwise)

Preceding gene: 15888374

Following gene: 15888376

Centisome position: 36.11

GC content: 59.01

Gene sequence:

>405_bases
ATGATCATTGGATTGGGCAGCGACCTGATCGACATCCGCCGCGTCGAAAAGTCGATCGAGCGTTTCGGCGAACGTTTCAC
GCATCGCTGTTTCACCGATATAGAGCGCGCCAAATCCGATGGCCGTAAAAACCGCGCCGCGTCTTACGCCAAGCGTTTCG
CCGCCAAGGAAGCCTGTTCCAAGGCGCTTGGAACGGGGCTTGCGAACGGCGTTTTCTGGAAGGATATGGGCGTCGTTAAT
CTGCCGGGCGGCAAACCGACCATGATCCTCACCAACGGGGCAGGGGCGAGGCTGGCGGCCATGCTGCCCGCCGGTCACCG
CGCCAATATCCATCTGACGATCACGGACGACTTTCCCTATGCTCAGGCATTTGTGATCATCGAGGCGCTTCCCGTGAATG
GGTAA

Upstream 100 bases:

>100_bases
ATATCGCCGTCTACGGCCTCATCAGCGGCTTCCAGCGGCGCAAGATGGAAAATCTCGCCCACCGCGCCGCCAATAAGAAT
GCTTCTCTGGAGATGTTGAA

Downstream 100 bases:

>100_bases
GGCGCGCTGCCGCCGTAAAGGCGCTCTATTTGCAGAGGTGTCACAGAAGCGCTTCCCTTCGGGCTGGAAAGGTTCTAGAG
AAGTCGCAGAAATATGAAAG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MIIGLGSDLIDIRRVEKSIERFGERFTHRCFTDIERAKSDGRKNRAASYAKRFAAKEACSKALGTGLANGVFWKDMGVVN
LPGGKPTMILTNGAGARLAAMLPAGHRANIHLTITDDFPYAQAFVIIEALPVNG

Sequences:

>Translated_134_residues
MIIGLGSDLIDIRRVEKSIERFGERFTHRCFTDIERAKSDGRKNRAASYAKRFAAKEACSKALGTGLANGVFWKDMGVVN
LPGGKPTMILTNGAGARLAAMLPAGHRANIHLTITDDFPYAQAFVIIEALPVNG
>Mature_134_residues
MIIGLGSDLIDIRRVEKSIERFGERFTHRCFTDIERAKSDGRKNRAASYAKRFAAKEACSKALGTGLANGVFWKDMGVVN
LPGGKPTMILTNGAGARLAAMLPAGHRANIHLTITDDFPYAQAFVIIEALPVNG

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=41.40625, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_AGRT5 (Q8UGK4)

Other databases:

- EMBL:   AE007869
- PIR:   AH2703
- PIR:   H97485
- RefSeq:   NP_354056.1
- ProteinModelPortal:   Q8UGK4
- SMR:   Q8UGK4
- STRING:   Q8UGK4
- GeneID:   1133071
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1033
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q8UGK4
- ProtClustDB:   PRK00070
- BioCyc:   ATUM176299-1:ATU1033-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14518; Mature: 14518

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGLGSDLIDIRRVEKSIERFGERFTHRCFTDIERAKSDGRKNRAASYAKRFAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KALGTGLANGVFWKDMGVVNLPGGKPTMILTNGAGARLAAMLPAGHRANIHLTITDDFPY
HHHHCCCCCCEEECCCCEEECCCCCCEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCC
AQAFVIIEALPVNG
HHEEEEEEEECCCC
>Mature Secondary Structure
MIIGLGSDLIDIRRVEKSIERFGERFTHRCFTDIERAKSDGRKNRAASYAKRFAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KALGTGLANGVFWKDMGVVNLPGGKPTMILTNGAGARLAAMLPAGHRANIHLTITDDFPY
HHHHCCCCCCEEECCCCEEECCCCCCEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCC
AQAFVIIEALPVNG
HHEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194