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The map label for this gene is mgsA

Identifier: 15887539

GI number: 15887539

Start: 187787

End: 188170

Strand: Reverse

Name: mgsA

Synonym: Atu0185

Alternate gene names: 15887539

Gene position: 188170-187787 (Counterclockwise)

Preceding gene: 15887540

Following gene: 159184201

Centisome position: 6.62

GC content: 60.16

Gene sequence:

>384_bases
ATGGAAGGGCAACGCTGTATCGCGCTCATCGCTCACGACGAGAAAAAGGACGATATGGCGGATTTCGCCCGTCACCATCA
GAAGGTGCTTGCCAGTTTCAGGATCGTCGCCACCGGCACCACCGGCGGGCGTGTGCAGGAAGCCTGCCCGGGGCTTGAGG
TCATCCGCCTCAAAAGCGGTCCTCTTGGCGGCGACCAGCAGATCGGCGCGATGATCGCCACTGGCGAAGTGGACATGCTG
ATCTTCTTTACCGATCCGCTGACTGCCATGCCGCATGATGTCGATGTGAAGGCGCTGACGCGTCTTGCCACGGTCTACGA
CATTCCCATGGCGCTCAACCGCGCCACCGCAGAAAACCTCATCGACTTCAATTCCGCCGACTGA

Upstream 100 bases:

>100_bases
AAACAGAAATGAGGCATTGAACAGCTTCCCTTTTCAAATGGCGGCAAGCTGTTATAGAAGGCTTCAAATCGATTTAATTC
TTTGAGGACAGGCTGGGACC

Downstream 100 bases:

>100_bases
CCCGAACCCACCACAATGGAACAGGCAATGCCGAAGACGTCCGATACCGAATATCTGTCCTTTCCGATCCTTCTTGGCGA
CATCGGCGGCACCAATGCCC

Product: methylglyoxal synthase

Products: NA

Alternate protein names: MGS

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MEGQRCIALIAHDEKKDDMADFARHHQKVLASFRIVATGTTGGRVQEACPGLEVIRLKSGPLGGDQQIGAMIATGEVDML
IFFTDPLTAMPHDVDVKALTRLATVYDIPMALNRATAENLIDFNSAD

Sequences:

>Translated_127_residues
MEGQRCIALIAHDEKKDDMADFARHHQKVLASFRIVATGTTGGRVQEACPGLEVIRLKSGPLGGDQQIGAMIATGEVDML
IFFTDPLTAMPHDVDVKALTRLATVYDIPMALNRATAENLIDFNSAD
>Mature_127_residues
MEGQRCIALIAHDEKKDDMADFARHHQKVLASFRIVATGTTGGRVQEACPGLEVIRLKSGPLGGDQQIGAMIATGEVDML
IFFTDPLTAMPHDVDVKALTRLATVYDIPMALNRATAENLIDFNSAD

Specific function: Unknown

COG id: COG1803

COG function: function code G; Methylglyoxal synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methylglyoxal synthase family

Homologues:

Organism=Escherichia coli, GI87081809, Length=129, Percent_Identity=49.6124031007752, Blast_Score=125, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MGSA_AGRT5 (Q8UIV6)

Other databases:

- EMBL:   AE007869
- PIR:   AC2599
- PIR:   D97381
- RefSeq:   NP_353220.1
- ProteinModelPortal:   Q8UIV6
- SMR:   Q8UIV6
- STRING:   Q8UIV6
- GeneID:   1132223
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0185
- eggNOG:   COG1803
- HOGENOM:   HBG298005
- OMA:   EPQPHDP
- PhylomeDB:   Q8UIV6
- ProtClustDB:   PRK05234
- BioCyc:   ATUM176299-1:ATU0185-MONOMER
- HAMAP:   MF_00549
- InterPro:   IPR004363
- InterPro:   IPR018148
- InterPro:   IPR011607
- Gene3D:   G3DSA:3.40.50.1380
- PIRSF:   PIRSF006614
- SMART:   SM00851
- TIGRFAMs:   TIGR00160

Pfam domain/function: PF02142 MGS; SSF52335 MGS-like_dom

EC number: =4.2.3.3

Molecular weight: Translated: 13753; Mature: 13753

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01335 METHYLGLYOXAL_SYNTH

Important sites: ACT_SITE 65-65

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGQRCIALIAHDEKKDDMADFARHHQKVLASFRIVATGTTGGRVQEACPGLEVIRLKSG
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHCCCCEEEEEECC
PLGGDQQIGAMIATGEVDMLIFFTDPLTAMPHDVDVKALTRLATVYDIPMALNRATAENL
CCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IDFNSAD
CCCCCCC
>Mature Secondary Structure
MEGQRCIALIAHDEKKDDMADFARHHQKVLASFRIVATGTTGGRVQEACPGLEVIRLKSG
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHCCCCEEEEEECC
PLGGDQQIGAMIATGEVDMLIFFTDPLTAMPHDVDVKALTRLATVYDIPMALNRATAENL
CCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IDFNSAD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194