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The map label for this gene is glk

Identifier: 159184201

GI number: 159184201

Start: 186737

End: 187759

Strand: Reverse

Name: glk

Synonym: Atu0184

Alternate gene names: 159184201

Gene position: 187759-186737 (Counterclockwise)

Preceding gene: 15887539

Following gene: 159184200

Centisome position: 6.61

GC content: 61.39

Gene sequence:

>1023_bases
ATGCCGAAGACGTCCGATACCGAATATCTGTCCTTTCCGATCCTTCTTGGCGACATCGGCGGCACCAATGCCCGCTTTTC
CATCCTGATCGATTCCTTTGCTGAACCGGTGCACCTCACCACGGTGAAGACGGCGGAATATCCTGGTATCGATGACGCGA
TCCAGCAGGCGGTTCTGGACAAGACCTCTCTTCAGCCGGTCTCGACCATTCTTGCAATTGCCGGCCCGATCGAAGGCGAC
GAGATTCCGTTGACCAACTGCCACTGGGTCGTCAAGCCGAAGGACATGCTGGCCAAGCTCGGCCTGAAGGACGTCATCGT
CATCAACGACTTTGAGGCGCAGGCTCTGGCGATTGCGGCTCTTGACGACGACAACCGGGAGCCTATCGGCTCCGGTAAAA
AGGACATGCTGGCGTCGCGCGTCGTTCTTGGACCGGGCACGGGGCTTGGCGTCGCCGGGCTGGTCTATGCCCGCCATATG
TGGTTTCCGGTGCCTGGCGAAGGCGGGCATATCGATATCGGCCCGAGAAGCGCGCGCGACTATGTGGTTTTCCCCCATAT
CGAAACCATCGAGGGCCGCGTCGCCGGCGAACAGATCCTGTGCGGACGCGGGCTGGTCAATCTTTATCGGGCCATCTGCA
AAGCCGACGGCATCGAGCCTGTCTTTTCCGATCCGGCCGACATCACCTCGCAGGGGCTTTCGGGCCAGAACGCGCAGGCA
AAAGAAACGCTGTCGCTGTTCAGCACCTATCTCGGCCGCGTGGCGGGCGACCTTGCGCTGATCTTCATGGCCAAGGGCGG
CGTTTATCTGGCCGGCGGTATTTCGCAGAAGATCATCCCTGCGCTGAAGAGCCCGGAATTCCGGGCGGCGTTCGAAGACA
AGGCGCCGCACAGCGCTCTGATGCGGACCATTCCGACATTCGTCGTCACCCATCCTCAGGCGGCCCTTTCCGGCCTCGCC
ACCTATGCGAGAACGCCTGCCGATTTCGGTCTTGCGCTGGACGGGCGGCGCTGGAGGGCTTGA

Upstream 100 bases:

>100_bases
GGTCTACGACATTCCCATGGCGCTCAACCGCGCCACCGCAGAAAACCTCATCGACTTCAATTCCGCCGACTGACCCGAAC
CCACCACAATGGAACAGGCA

Downstream 100 bases:

>100_bases
TCGCTCTCCTCTCAAAGGGGGCTATCCTTCCTATGTGATGCTTGCGAAGCGGGCGGGCGATCTTTAACGTCGCTGCTGCA
AACATCAATCGACCGATACC

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MPKTSDTEYLSFPILLGDIGGTNARFSILIDSFAEPVHLTTVKTAEYPGIDDAIQQAVLDKTSLQPVSTILAIAGPIEGD
EIPLTNCHWVVKPKDMLAKLGLKDVIVINDFEAQALAIAALDDDNREPIGSGKKDMLASRVVLGPGTGLGVAGLVYARHM
WFPVPGEGGHIDIGPRSARDYVVFPHIETIEGRVAGEQILCGRGLVNLYRAICKADGIEPVFSDPADITSQGLSGQNAQA
KETLSLFSTYLGRVAGDLALIFMAKGGVYLAGGISQKIIPALKSPEFRAAFEDKAPHSALMRTIPTFVVTHPQAALSGLA
TYARTPADFGLALDGRRWRA

Sequences:

>Translated_340_residues
MPKTSDTEYLSFPILLGDIGGTNARFSILIDSFAEPVHLTTVKTAEYPGIDDAIQQAVLDKTSLQPVSTILAIAGPIEGD
EIPLTNCHWVVKPKDMLAKLGLKDVIVINDFEAQALAIAALDDDNREPIGSGKKDMLASRVVLGPGTGLGVAGLVYARHM
WFPVPGEGGHIDIGPRSARDYVVFPHIETIEGRVAGEQILCGRGLVNLYRAICKADGIEPVFSDPADITSQGLSGQNAQA
KETLSLFSTYLGRVAGDLALIFMAKGGVYLAGGISQKIIPALKSPEFRAAFEDKAPHSALMRTIPTFVVTHPQAALSGLA
TYARTPADFGLALDGRRWRA
>Mature_339_residues
PKTSDTEYLSFPILLGDIGGTNARFSILIDSFAEPVHLTTVKTAEYPGIDDAIQQAVLDKTSLQPVSTILAIAGPIEGDE
IPLTNCHWVVKPKDMLAKLGLKDVIVINDFEAQALAIAALDDDNREPIGSGKKDMLASRVVLGPGTGLGVAGLVYARHMW
FPVPGEGGHIDIGPRSARDYVVFPHIETIEGRVAGEQILCGRGLVNLYRAICKADGIEPVFSDPADITSQGLSGQNAQAK
ETLSLFSTYLGRVAGDLALIFMAKGGVYLAGGISQKIIPALKSPEFRAAFEDKAPHSALMRTIPTFVVTHPQAALSGLAT
YARTPADFGLALDGRRWRA

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family

Homologues:

Organism=Escherichia coli, GI1788732, Length=310, Percent_Identity=36.4516129032258, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLK_AGRT5 (Q8UIV7)

Other databases:

- EMBL:   AE007869
- PIR:   AB2599
- PIR:   C97381
- RefSeq:   NP_353219.2
- STRING:   Q8UIV7
- GeneID:   1132222
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0184
- eggNOG:   COG0837
- HOGENOM:   HBG644410
- OMA:   LGMTRLK
- PhylomeDB:   Q8UIV7
- ProtClustDB:   PRK00292
- BioCyc:   ATUM176299-1:ATU0184-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00524
- InterPro:   IPR003836
- TIGRFAMs:   TIGR00749

Pfam domain/function: PF02685 Glucokinase

EC number: =2.7.1.2

Molecular weight: Translated: 36244; Mature: 36113

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTSDTEYLSFPILLGDIGGTNARFSILIDSFAEPVHLTTVKTAEYPGIDDAIQQAVLD
CCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHH
KTSLQPVSTILAIAGPIEGDEIPLTNCHWVVKPKDMLAKLGLKDVIVINDFEAQALAIAA
HCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEEEECCCCCEEEEEE
LDDDNREPIGSGKKDMLASRVVLGPGTGLGVAGLVYARHMWFPVPGEGGHIDIGPRSARD
ECCCCCCCCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHEECCCCCCCEEECCCCCCCC
YVVFPHIETIEGRVAGEQILCGRGLVNLYRAICKADGIEPVFSDPADITSQGLSGQNAQA
EEEECCHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHH
KETLSLFSTYLGRVAGDLALIFMAKGGVYLAGGISQKIIPALKSPEFRAAFEDKAPHSAL
HHHHHHHHHHHHHHHHHEEEEEEECCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCHHHH
MRTIPTFVVTHPQAALSGLATYARTPADFGLALDGRRWRA
HHHHHHHEEECCHHHHHHHHHHHCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
PKTSDTEYLSFPILLGDIGGTNARFSILIDSFAEPVHLTTVKTAEYPGIDDAIQQAVLD
CCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHH
KTSLQPVSTILAIAGPIEGDEIPLTNCHWVVKPKDMLAKLGLKDVIVINDFEAQALAIAA
HCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEEEECCCCCEEEEEE
LDDDNREPIGSGKKDMLASRVVLGPGTGLGVAGLVYARHMWFPVPGEGGHIDIGPRSARD
ECCCCCCCCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHEECCCCCCCEEECCCCCCCC
YVVFPHIETIEGRVAGEQILCGRGLVNLYRAICKADGIEPVFSDPADITSQGLSGQNAQA
EEEECCHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHH
KETLSLFSTYLGRVAGDLALIFMAKGGVYLAGGISQKIIPALKSPEFRAAFEDKAPHSAL
HHHHHHHHHHHHHHHHHEEEEEEECCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCHHHH
MRTIPTFVVTHPQAALSGLATYARTPADFGLALDGRRWRA
HHHHHHHEEECCHHHHHHHHHHHCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194