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The map label for this gene is 158423978

Identifier: 158423978

GI number: 158423978

Start: 2680293

End: 2681912

Strand: Reverse

Name: 158423978

Synonym: AZC_2354

Alternate gene names: NA

Gene position: 2681912-2680293 (Counterclockwise)

Preceding gene: 158423979

Following gene: 158423977

Centisome position: 49.94

GC content: 67.22

Gene sequence:

>1620_bases
ATGAGCGAAATCGACGACATCCGTATGCAGGTGATGTGGAATCGCCTGATCTCGGTGGTGGAAGAGCAGGCGATGACCCT
GCTGCGCACGGCCTTCTCGACCTCGGTGCGCGAGGCGGGCGACCTGTCCGCCGGAGTGTTCGACCCGATGGGCCGCATGC
TGGCGCAGGCGGTCACCGGAACACCGGGCCATGTGAACACCATGGCCGAGGCGGTGGGGAACTTCATGGCGGAGATCCCC
CGCGCCGAGATGTACGAGGGCGACACCTATGTCACCAACGACCCGTGGAAGGGCACCGGGCATCTGCACGACATCACCAT
GGTGTCCCCATCCTTCCTCGACGGGGAGCTGGTCGGCTTCTTCGCCTGCACCGCCCATGTGGTGGATGTTGGCGGGCGTG
GTTTCGGGGCGGACGGCAAGTCCGTCTATGAGGAAGGCATCCAGATCCCGATCATGAAGTTCGCCGAGCGCGGCACGGTG
AACCGGGACCTCGTCCGCATCCTGCGCCAGAATGTGCGTGAGCCCAATCAGGTGGTCGGCGATTTCTATTCGCTCGCAGC
GTGTAACGACGTGGGCCATCGTCGCCTCGTGGAGATGATGCGCGAAGTGGGCCTCGCCAGCCTCGATCCGCTGGCGGATT
TCATCTTCACGCGCACCAGCAGCGCCATGGCCGAACGCATCCGCGCCCTGCCCAAGGGCTCTTGGTCCAACACCATGGTC
ACTGATGGCTATGATGAGGCGATCCCGCTTGCCGCTTGCGTCACCATTCGGGACGAGAGCGTGCATGTGGACTTCACCGG
CAGCGCGCCGGTGAGCCGATGGGGCATCAACGTGCCCATCAGCTACACCAAGGCCTATGCCTCCTATGCGCTGAAGTGCG
TGGTGGCCCCGGACATTCCGAACAACTGGGCCTCGCTCGGCTTCTTCACCGTGTCCTCGCCGGTGAACATCCTCAATGCG
GAGCGTCCGGCGCCCGTGAGCTTGCGCCATGTGCTCGGCCACCTCGTGCCGGATCTGGTGCTCGGCGCCGTCGCGGATGC
CCTGCCGGGGCAGGTGCTCGCGGAAGGCGCGGCCTCGCTGTGGAACATCCATCTCTCGCTGCGGCCGGTGGCGGGCGGGG
CCGGCCGCCGCGCGGAAGTGCTGATGTTCAACTCGGGGGGCATGGGCGCGCGCCCCGGGCTCGACGGGCTCTCGGCCACG
GCCTTCCCCTCGGGCGTCCACACCATGCCCATCGAGGCCACGGAACAGACCGGCCCGGTGGTGATCTGGCGCAAGGAACT
GCGGCCCGATTCCGGCGGCGACGGCACCTATCGGGGCGGCCTTGGCCAGATCATCGAGATCGCCGCCGCCGAGGGGCATG
AGTTCGATTTCTCGGCCATGTTCGATCGCATCACCTATCCCGCCCGAGGCCGCGCCGGGGGAGGGCAGGGCGCGCCTGGC
GGCGTCCGCCTTGACGACGGCACGAAGATGCGCGGCAAGGGCTGGCAGCATGTGCCAGCGGGCCGCCGGCTCATTCTCAC
CCTGCCGGGTGGCGGCGGCTACGGGCCGCCCGAGGGACGTTCGGATGCGGCGCGGCATGACGATGCCATCAAGGGGTATG
TGACGGAAAGCGAGCACTGA

Upstream 100 bases:

>100_bases
TGATCGTGGAGCGGGAGACCGCCACGGTCATCACCTCTCTCTTCGATGCCGTGCTGCAGAGCGACGGCTCCATCCTCCTC
GTCCGCAAGGGCCGCCACTG

Downstream 100 bases:

>100_bases
ACGGGAGCCCGCCCGGCTTAAGGCGTTCTGTCCGGTCGGCTCTCGCCTCACCGGGAGGCCTGAGACGCGCCCCTGCACGG
AGGCGGGGGCACCTTCCCGT

Product: hydantoinase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MSEIDDIRMQVMWNRLISVVEEQAMTLLRTAFSTSVREAGDLSAGVFDPMGRMLAQAVTGTPGHVNTMAEAVGNFMAEIP
RAEMYEGDTYVTNDPWKGTGHLHDITMVSPSFLDGELVGFFACTAHVVDVGGRGFGADGKSVYEEGIQIPIMKFAERGTV
NRDLVRILRQNVREPNQVVGDFYSLAACNDVGHRRLVEMMREVGLASLDPLADFIFTRTSSAMAERIRALPKGSWSNTMV
TDGYDEAIPLAACVTIRDESVHVDFTGSAPVSRWGINVPISYTKAYASYALKCVVAPDIPNNWASLGFFTVSSPVNILNA
ERPAPVSLRHVLGHLVPDLVLGAVADALPGQVLAEGAASLWNIHLSLRPVAGGAGRRAEVLMFNSGGMGARPGLDGLSAT
AFPSGVHTMPIEATEQTGPVVIWRKELRPDSGGDGTYRGGLGQIIEIAAAEGHEFDFSAMFDRITYPARGRAGGGQGAPG
GVRLDDGTKMRGKGWQHVPAGRRLILTLPGGGGYGPPEGRSDAARHDDAIKGYVTESEH

Sequences:

>Translated_539_residues
MSEIDDIRMQVMWNRLISVVEEQAMTLLRTAFSTSVREAGDLSAGVFDPMGRMLAQAVTGTPGHVNTMAEAVGNFMAEIP
RAEMYEGDTYVTNDPWKGTGHLHDITMVSPSFLDGELVGFFACTAHVVDVGGRGFGADGKSVYEEGIQIPIMKFAERGTV
NRDLVRILRQNVREPNQVVGDFYSLAACNDVGHRRLVEMMREVGLASLDPLADFIFTRTSSAMAERIRALPKGSWSNTMV
TDGYDEAIPLAACVTIRDESVHVDFTGSAPVSRWGINVPISYTKAYASYALKCVVAPDIPNNWASLGFFTVSSPVNILNA
ERPAPVSLRHVLGHLVPDLVLGAVADALPGQVLAEGAASLWNIHLSLRPVAGGAGRRAEVLMFNSGGMGARPGLDGLSAT
AFPSGVHTMPIEATEQTGPVVIWRKELRPDSGGDGTYRGGLGQIIEIAAAEGHEFDFSAMFDRITYPARGRAGGGQGAPG
GVRLDDGTKMRGKGWQHVPAGRRLILTLPGGGGYGPPEGRSDAARHDDAIKGYVTESEH
>Mature_538_residues
SEIDDIRMQVMWNRLISVVEEQAMTLLRTAFSTSVREAGDLSAGVFDPMGRMLAQAVTGTPGHVNTMAEAVGNFMAEIPR
AEMYEGDTYVTNDPWKGTGHLHDITMVSPSFLDGELVGFFACTAHVVDVGGRGFGADGKSVYEEGIQIPIMKFAERGTVN
RDLVRILRQNVREPNQVVGDFYSLAACNDVGHRRLVEMMREVGLASLDPLADFIFTRTSSAMAERIRALPKGSWSNTMVT
DGYDEAIPLAACVTIRDESVHVDFTGSAPVSRWGINVPISYTKAYASYALKCVVAPDIPNNWASLGFFTVSSPVNILNAE
RPAPVSLRHVLGHLVPDLVLGAVADALPGQVLAEGAASLWNIHLSLRPVAGGAGRRAEVLMFNSGGMGARPGLDGLSATA
FPSGVHTMPIEATEQTGPVVIWRKELRPDSGGDGTYRGGLGQIIEIAAAEGHEFDFSAMFDRITYPARGRAGGGQGAPGG
VRLDDGTKMRGKGWQHVPAGRRLILTLPGGGGYGPPEGRSDAARHDDAIKGYVTESEH

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=547, Percent_Identity=28.8848263254113, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI133901900, Length=553, Percent_Identity=26.0397830018083, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI133901902, Length=542, Percent_Identity=25.4612546125461, Blast_Score=111, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6322634, Length=553, Percent_Identity=25.6781193490054, Blast_Score=136, Evalue=8e-33,
Organism=Drosophila melanogaster, GI45550492, Length=566, Percent_Identity=27.3851590106007, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: NA

Molecular weight: Translated: 57660; Mature: 57529

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIDDIRMQVMWNRLISVVEEQAMTLLRTAFSTSVREAGDLSAGVFDPMGRMLAQAVTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
TPGHVNTMAEAVGNFMAEIPRAEMYEGDTYVTNDPWKGTGHLHDITMVSPSFLDGELVGF
CCCHHHHHHHHHHHHHHHCCCCHHCCCCEEEECCCCCCCCCEEEEEEECCCCCCCHHHHH
FACTAHVVDVGGRGFGADGKSVYEEGIQIPIMKFAERGTVNRDLVRILRQNVREPNQVVG
HHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHH
DFYSLAACNDVGHRRLVEMMREVGLASLDPLADFIFTRTSSAMAERIRALPKGSWSNTMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEE
TDGYDEAIPLAACVTIRDESVHVDFTGSAPVSRWGINVPISYTKAYASYALKCVVAPDIP
ECCCCCCCCEEEEEEEECCEEEEEECCCCCHHHCCCCCCHHHHHHHHHHEEEEEECCCCC
NNWASLGFFTVSSPVNILNAERPAPVSLRHVLGHLVPDLVLGAVADALPGQVLAEGAASL
CCCHHEEEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEE
WNIHLSLRPVAGGAGRRAEVLMFNSGGMGARPGLDGLSATAFPSGVHTMPIEATEQTGPV
EEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCE
VIWRKELRPDSGGDGTYRGGLGQIIEIAAAEGHEFDFSAMFDRITYPARGRAGGGQGAPG
EEEHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
GVRLDDGTKMRGKGWQHVPAGRRLILTLPGGGGYGPPEGRSDAARHDDAIKGYVTESEH
CEEECCCCEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCHHCCCEECCCC
>Mature Secondary Structure 
SEIDDIRMQVMWNRLISVVEEQAMTLLRTAFSTSVREAGDLSAGVFDPMGRMLAQAVTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
TPGHVNTMAEAVGNFMAEIPRAEMYEGDTYVTNDPWKGTGHLHDITMVSPSFLDGELVGF
CCCHHHHHHHHHHHHHHHCCCCHHCCCCEEEECCCCCCCCCEEEEEEECCCCCCCHHHHH
FACTAHVVDVGGRGFGADGKSVYEEGIQIPIMKFAERGTVNRDLVRILRQNVREPNQVVG
HHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHH
DFYSLAACNDVGHRRLVEMMREVGLASLDPLADFIFTRTSSAMAERIRALPKGSWSNTMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEE
TDGYDEAIPLAACVTIRDESVHVDFTGSAPVSRWGINVPISYTKAYASYALKCVVAPDIP
ECCCCCCCCEEEEEEEECCEEEEEECCCCCHHHCCCCCCHHHHHHHHHHEEEEEECCCCC
NNWASLGFFTVSSPVNILNAERPAPVSLRHVLGHLVPDLVLGAVADALPGQVLAEGAASL
CCCHHEEEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEE
WNIHLSLRPVAGGAGRRAEVLMFNSGGMGARPGLDGLSATAFPSGVHTMPIEATEQTGPV
EEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCE
VIWRKELRPDSGGDGTYRGGLGQIIEIAAAEGHEFDFSAMFDRITYPARGRAGGGQGAPG
EEEHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
GVRLDDGTKMRGKGWQHVPAGRRLILTLPGGGGYGPPEGRSDAARHDDAIKGYVTESEH
CEEECCCCEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]