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The map label for this gene is pqqL [C]

Identifier: 158423864

GI number: 158423864

Start: 2559255

End: 2560535

Strand: Direct

Name: pqqL [C]

Synonym: AZC_2240

Alternate gene names: 158423864

Gene position: 2559255-2560535 (Clockwise)

Preceding gene: 158423863

Following gene: 158423865

Centisome position: 47.66

GC content: 68.62

Gene sequence:

>1281_bases
ATGAGCGCGACAGAGACCGGCGTTAAGACGACGACCCTGCCGAACGGCATCACGGTCGTCTCAGATGCCATGCCTCACCT
CGGCACGGCCTCGCTCGGCATCTGGGTGGGGGCCGGCGCGCGCGACGAGGGCGAGCAGGAACACGGCATCTCGCACCTTC
TGGAACACATGGCCTTCAAGGGCACGCGCCGCCGCTCGGCTCGCCGCATCGCGGAGGAGATCGAGCAGGTGGGCGGCGAC
ATCAATGCCGCCACCTCCGTCGAGCAGACGTCCTACAATGTGCGGGTGCTGGGCGAGGACGTGGGCCTCGGCATGGACAT
CCTGTCGGACATCCTCACCGAGCCCGCTTTCGCGCCCGAGGAACTGGCGCGCGAGAAGAACGTGATCGTGCAGGAAATCG
GCGCGGTCATGGACACGCCGGACGATCTCGTGTTCGACCTGTTCCAGGAGCGCGCCTTTCCGGGGCAGGCGGTGGGCCGC
TCCATCCTCGGCACGCCGGACACGGTGCGCAGCTTCGATCCCGCGGGCCTCGGCGCCTATCTGGGCCGCACCTATCGCGG
GCCGCGCATGGTGGTCTCCGCCGCCGGCGCCGTGAACCACGACCAGCTTGTGGCCGAGGCTGCCGAGCGGCTCGGCACCA
TCGCCGGCGAGACCAAGCCTGAGGCTGCGCCCGCGCTTTATGCCGGCGGCAGCATCCTCACCCCGCGCGACCTTGAGCAG
GTGCACGTGGTGCTGGGCCTTGAGGGGCGCTCCTACAAGCATCCGCAGTATCATGCGGCGCAGGTACTCTCGAACATCCT
CGGCGGCGGCATGTCCTCGCGCCTGTTTCAGGATGTGCGGGAGGAGCGGGGCCTCTGCTATTCCATCTATTCCTTCCACT
GGTCCTATGCGGACACCGGCATCTTCGCCATCTATGCCGGCACCGATGAAGGCGATGTGGGCGAGCTGACCAATGTGGTC
ATCGACCAACTGGAAGCGGCGGGTGAGACCATCACGGAAACGGAGCTCGCCCGCGCCAAGGCGCAGATGAAGGTGGGCCT
TCTCGCCGCGCTGGAAAGTTCAGGCGCCCGCGCCGACCAGCTCGCCCGGCAGTTGCTGGCCTTCAACCGCATCATTCCGG
TGGAGGAGATCGTCGCCAAGGTGGAGGCCGTCACCGTGGACGCGGTGCGGCAGGCCGCGCGCGATCTCGTGGCCGGCGGT
CGGCCGACGCTGGCCGCCATCGGTCCGGGCAAGGGGCTCGATCCGGCAGCGCGCGCGGTGGAGCGCCTGGCCGGCGCCTG
A

Upstream 100 bases:

>100_bases
TGTTCAACCGCAAGGAGCGCCTGAGCGTGCTGCCGAACGATCTCGACGCCATCGAGGCCTTCATCTCGGCGCGGGCGCGG
ATCGTCTCGGGAGCCGCCGC

Downstream 100 bases:

>100_bases
TCGGGTTTCTCCTGATTTGAGGTGCGGCGCAAACAGGTTCTAGAATGAGACTGCCGTGCGCCCCCGGGAGCACGGCAGGG
GTTATTGCCGTCATGTGGCT

Product: mitochondrial processing peptidase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSATETGVKTTTLPNGITVVSDAMPHLGTASLGIWVGAGARDEGEQEHGISHLLEHMAFKGTRRRSARRIAEEIEQVGGD
INAATSVEQTSYNVRVLGEDVGLGMDILSDILTEPAFAPEELAREKNVIVQEIGAVMDTPDDLVFDLFQERAFPGQAVGR
SILGTPDTVRSFDPAGLGAYLGRTYRGPRMVVSAAGAVNHDQLVAEAAERLGTIAGETKPEAAPALYAGGSILTPRDLEQ
VHVVLGLEGRSYKHPQYHAAQVLSNILGGGMSSRLFQDVREERGLCYSIYSFHWSYADTGIFAIYAGTDEGDVGELTNVV
IDQLEAAGETITETELARAKAQMKVGLLAALESSGARADQLARQLLAFNRIIPVEEIVAKVEAVTVDAVRQAARDLVAGG
RPTLAAIGPGKGLDPAARAVERLAGA

Sequences:

>Translated_426_residues
MSATETGVKTTTLPNGITVVSDAMPHLGTASLGIWVGAGARDEGEQEHGISHLLEHMAFKGTRRRSARRIAEEIEQVGGD
INAATSVEQTSYNVRVLGEDVGLGMDILSDILTEPAFAPEELAREKNVIVQEIGAVMDTPDDLVFDLFQERAFPGQAVGR
SILGTPDTVRSFDPAGLGAYLGRTYRGPRMVVSAAGAVNHDQLVAEAAERLGTIAGETKPEAAPALYAGGSILTPRDLEQ
VHVVLGLEGRSYKHPQYHAAQVLSNILGGGMSSRLFQDVREERGLCYSIYSFHWSYADTGIFAIYAGTDEGDVGELTNVV
IDQLEAAGETITETELARAKAQMKVGLLAALESSGARADQLARQLLAFNRIIPVEEIVAKVEAVTVDAVRQAARDLVAGG
RPTLAAIGPGKGLDPAARAVERLAGA
>Mature_425_residues
SATETGVKTTTLPNGITVVSDAMPHLGTASLGIWVGAGARDEGEQEHGISHLLEHMAFKGTRRRSARRIAEEIEQVGGDI
NAATSVEQTSYNVRVLGEDVGLGMDILSDILTEPAFAPEELAREKNVIVQEIGAVMDTPDDLVFDLFQERAFPGQAVGRS
ILGTPDTVRSFDPAGLGAYLGRTYRGPRMVVSAAGAVNHDQLVAEAAERLGTIAGETKPEAAPALYAGGSILTPRDLEQV
HVVLGLEGRSYKHPQYHAAQVLSNILGGGMSSRLFQDVREERGLCYSIYSFHWSYADTGIFAIYAGTDEGDVGELTNVVI
DQLEAAGETITETELARAKAQMKVGLLAALESSGARADQLARQLLAFNRIIPVEEIVAKVEAVTVDAVRQAARDLVAGGR
PTLAAIGPGKGLDPAARAVERLAGA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=419, Percent_Identity=33.890214797136, Blast_Score=252, Evalue=5e-67,
Organism=Homo sapiens, GI46593007, Length=415, Percent_Identity=29.6385542168675, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI24308013, Length=433, Percent_Identity=28.175519630485, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI50592988, Length=412, Percent_Identity=24.2718446601942, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71999683, Length=410, Percent_Identity=31.7073170731707, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17553678, Length=420, Percent_Identity=27.3809523809524, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17510601, Length=444, Percent_Identity=25.4504504504505, Blast_Score=124, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6323192, Length=427, Percent_Identity=32.7868852459016, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6321813, Length=429, Percent_Identity=28.4382284382284, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6319426, Length=424, Percent_Identity=24.2924528301887, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357875, Length=416, Percent_Identity=33.1730769230769, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24646943, Length=416, Percent_Identity=33.1730769230769, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI19921772, Length=457, Percent_Identity=23.6323851203501, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24665395, Length=410, Percent_Identity=25.3658536585366, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 45133; Mature: 45002

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATETGVKTTTLPNGITVVSDAMPHLGTASLGIWVGAGARDEGEQEHGISHLLEHMAFK
CCCCCCCCEEEECCCCCEEHHHCCCCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHC
GTRRRSARRIAEEIEQVGGDINAATSVEQTSYNVRVLGEDVGLGMDILSDILTEPAFAPE
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCHH
ELAREKNVIVQEIGAVMDTPDDLVFDLFQERAFPGQAVGRSILGTPDTVRSFDPAGLGAY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCHHHCCCCHHHHCCCCCCHHHH
LGRTYRGPRMVVSAAGAVNHDQLVAEAAERLGTIAGETKPEAAPALYAGGSILTPRDLEQ
HHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCHHH
VHVVLGLEGRSYKHPQYHAAQVLSNILGGGMSSRLFQDVREERGLCYSIYSFHWSYADTG
EEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHHHCCCCC
IFAIYAGTDEGDVGELTNVVIDQLEAAGETITETELARAKAQMKVGLLAALESSGARADQ
EEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LARQLLAFNRIIPVEEIVAKVEAVTVDAVRQAARDLVAGGRPTLAAIGPGKGLDPAARAV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHH
ERLAGA
HHHHCC
>Mature Secondary Structure 
SATETGVKTTTLPNGITVVSDAMPHLGTASLGIWVGAGARDEGEQEHGISHLLEHMAFK
CCCCCCCEEEECCCCCEEHHHCCCCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHC
GTRRRSARRIAEEIEQVGGDINAATSVEQTSYNVRVLGEDVGLGMDILSDILTEPAFAPE
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCHH
ELAREKNVIVQEIGAVMDTPDDLVFDLFQERAFPGQAVGRSILGTPDTVRSFDPAGLGAY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCHHHCCCCHHHHCCCCCCHHHH
LGRTYRGPRMVVSAAGAVNHDQLVAEAAERLGTIAGETKPEAAPALYAGGSILTPRDLEQ
HHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCHHH
VHVVLGLEGRSYKHPQYHAAQVLSNILGGGMSSRLFQDVREERGLCYSIYSFHWSYADTG
EEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHHHCCCCC
IFAIYAGTDEGDVGELTNVVIDQLEAAGETITETELARAKAQMKVGLLAALESSGARADQ
EEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LARQLLAFNRIIPVEEIVAKVEAVTVDAVRQAARDLVAGGRPTLAAIGPGKGLDPAARAV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHH
ERLAGA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA