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The map label for this gene is 158423740

Identifier: 158423740

GI number: 158423740

Start: 2432876

End: 2434588

Strand: Direct

Name: 158423740

Synonym: AZC_2116

Alternate gene names: NA

Gene position: 2432876-2434588 (Clockwise)

Preceding gene: 158423739

Following gene: 158423741

Centisome position: 45.31

GC content: 67.89

Gene sequence:

>1713_bases
ATGACCGCCATCGACCCCGTCACACTCGCCGTCCTGAAGGGGCGGCTGGAGCAGATCGCCGACGAGATGGATGCGACGCT
CTACCGCTCCGCTTTCAATCCCATCATCGCCGAGGCCCGTGACGCCTGCCACGGCCTCTATCATGCGGAAACCGGCGACA
CGCTGGTGCAGGGCACCAAGGGCCTGCCGATCTTCGTGGGCGCGATGGCCTTCGCGGTGCGGGCGGTGATCGAGAAGGTG
GCGCGCGACGGCGACCTCCAGCCGGGCGACAGCTTCCTGTTCAACGACCCCTATGCGGGCGGCACGCATCTGAACGATTT
CCGCCTCGTGCGGCCGATCTTCCGGGGCGGCAAGCTCTATTGCTGGCTGGCCTCCGTGGGCCACTGGCTGGACATCGGCG
GCAATGTCCCCGGCGGCTTCAACGCGCGGGCGACGGAGAGCTTCCAGGAAGGCGTGCGCATTCCGCCCGTGAAGCTGTTC
AAGGCCGGCGTGCTCAATCACGACATCATCGAGATACTCTCGGCCAATTCCCGCGTGCCGGTCTCCAACTATGGCGACCT
CAACGGCCAATTGAACGCGCTCGATCTCGGTGAGCGGCGGCTGGCGGAACTGCTCGACGCCTATGGCGAGAACATCGTGG
CGCAGGCCTTCGATGCCTTCTCCGACCGCGCCGAGGCCATGATGCGCGCCGCCATCCGCGCCCTGCCGGACGGCATCTAT
TCGTTCGAGGATTATCTCGACAATGACGGCATCACGCCGGACCGCCTGACCATCGCCCTCGACCTGACGGTGGACGGCGA
AAAGATGACGCTCGATTTCTCGCGCTCCTCCGCCCCCTGCGCAGGGCCGCTCAACATCGCCTATTCCACGGCGGCGGCCT
GCTGCTATGTGGCGCTGAAGCACGTCTTCACCGACGTTCCGGCCAATGCCGGGTGCCTCAGGCCCATCACCTTCGTCATC
CCCGAGACGACGCTGCTGGGTGTGAAGCCGCCCAAGCCCGTGGGCGGCTATACGGAGACGATCCTGCGCGTCATCGGCGT
CGTCTTCGGCGCGCTGGCCAAGGCTGACCCCGCCCGCGCCACGGCCGCGCCCTTCGGGACCATCAACGCCCTCTCGCTCG
CCGGCCACCGGCCGGATGGATCGCGCTGGGTGATGTTCTCCTTCTTCGGCGGCGGCCTCGGCGGCAATCCGGAGAGCGAT
GGCCTCAGCCACGCCAACAACCCCATTTCCATGGCCACCATTCCGCCGGCCGAGATTTTGGAAGCCGCCTATCCCGTGCT
GTTCACCCAGTGGGCGCTGCGGCCGGATTCCGCTGGCGCTGGCGCCCATCGCGGCGGCCTCGGCGCGGTCTATGAGATCG
AGCCGCTCACCGATGCGGATGTGTTTCTGCTCGGCGAGCGCGGCATCTATCCCCCCTTCGGGGTGGCTGGCGGCACGCCC
GCCGCGCTGAACGTCTTCTCGTGGGAGACCGAGGATGGCGAGCGCTCGCCCCCGCTCGCCTCCAAGGTGACGGACGTGAA
GGTGCGCGCCGGCCAGCGCGTGCGCCTGGAAACCCCCGGCGGTGGCGGCTACGGCGACCCCAAGGACCGCAAGCGCGAGG
ATGTGGAGCGCGATGTCCGGCAGGGCCTCGTGAGCGTTGAAGCCGCCCGCACCCTCTATGGCGTCGAGATCACGCCGGAC
ACCACCATTCCGGCGCAGGGAGCAGCCGCATGA

Upstream 100 bases:

>100_bases
ACGGCCTCATCGGCACCGCCGACCTGCTGGCCCAAGGGCGTGAGTATGATGTCTTCGGCGCGGCTCTGGCCGATGCGCCG
CTCACCAGGAAAGCCGCGCG

Downstream 100 bases:

>100_bases
ACGCCCATACCGCAACCCCTGAGGCCAAGCCCGCGCCGGTGGTCGGCGTGGATGTGGGCGGCACCTTCACCGACCTCTTC
TTCTTCGATGCCGCCGCCGG

Product: hydantoin utilization protein B

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MTAIDPVTLAVLKGRLEQIADEMDATLYRSAFNPIIAEARDACHGLYHAETGDTLVQGTKGLPIFVGAMAFAVRAVIEKV
ARDGDLQPGDSFLFNDPYAGGTHLNDFRLVRPIFRGGKLYCWLASVGHWLDIGGNVPGGFNARATESFQEGVRIPPVKLF
KAGVLNHDIIEILSANSRVPVSNYGDLNGQLNALDLGERRLAELLDAYGENIVAQAFDAFSDRAEAMMRAAIRALPDGIY
SFEDYLDNDGITPDRLTIALDLTVDGEKMTLDFSRSSAPCAGPLNIAYSTAAACCYVALKHVFTDVPANAGCLRPITFVI
PETTLLGVKPPKPVGGYTETILRVIGVVFGALAKADPARATAAPFGTINALSLAGHRPDGSRWVMFSFFGGGLGGNPESD
GLSHANNPISMATIPPAEILEAAYPVLFTQWALRPDSAGAGAHRGGLGAVYEIEPLTDADVFLLGERGIYPPFGVAGGTP
AALNVFSWETEDGERSPPLASKVTDVKVRAGQRVRLETPGGGGYGDPKDRKREDVERDVRQGLVSVEAARTLYGVEITPD
TTIPAQGAAA

Sequences:

>Translated_570_residues
MTAIDPVTLAVLKGRLEQIADEMDATLYRSAFNPIIAEARDACHGLYHAETGDTLVQGTKGLPIFVGAMAFAVRAVIEKV
ARDGDLQPGDSFLFNDPYAGGTHLNDFRLVRPIFRGGKLYCWLASVGHWLDIGGNVPGGFNARATESFQEGVRIPPVKLF
KAGVLNHDIIEILSANSRVPVSNYGDLNGQLNALDLGERRLAELLDAYGENIVAQAFDAFSDRAEAMMRAAIRALPDGIY
SFEDYLDNDGITPDRLTIALDLTVDGEKMTLDFSRSSAPCAGPLNIAYSTAAACCYVALKHVFTDVPANAGCLRPITFVI
PETTLLGVKPPKPVGGYTETILRVIGVVFGALAKADPARATAAPFGTINALSLAGHRPDGSRWVMFSFFGGGLGGNPESD
GLSHANNPISMATIPPAEILEAAYPVLFTQWALRPDSAGAGAHRGGLGAVYEIEPLTDADVFLLGERGIYPPFGVAGGTP
AALNVFSWETEDGERSPPLASKVTDVKVRAGQRVRLETPGGGGYGDPKDRKREDVERDVRQGLVSVEAARTLYGVEITPD
TTIPAQGAAA
>Mature_569_residues
TAIDPVTLAVLKGRLEQIADEMDATLYRSAFNPIIAEARDACHGLYHAETGDTLVQGTKGLPIFVGAMAFAVRAVIEKVA
RDGDLQPGDSFLFNDPYAGGTHLNDFRLVRPIFRGGKLYCWLASVGHWLDIGGNVPGGFNARATESFQEGVRIPPVKLFK
AGVLNHDIIEILSANSRVPVSNYGDLNGQLNALDLGERRLAELLDAYGENIVAQAFDAFSDRAEAMMRAAIRALPDGIYS
FEDYLDNDGITPDRLTIALDLTVDGEKMTLDFSRSSAPCAGPLNIAYSTAAACCYVALKHVFTDVPANAGCLRPITFVIP
ETTLLGVKPPKPVGGYTETILRVIGVVFGALAKADPARATAAPFGTINALSLAGHRPDGSRWVMFSFFGGGLGGNPESDG
LSHANNPISMATIPPAEILEAAYPVLFTQWALRPDSAGAGAHRGGLGAVYEIEPLTDADVFLLGERGIYPPFGVAGGTPA
ALNVFSWETEDGERSPPLASKVTDVKVRAGQRVRLETPGGGGYGDPKDRKREDVERDVRQGLVSVEAARTLYGVEITPDT
TIPAQGAAA

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=548, Percent_Identity=33.2116788321168, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI133901900, Length=556, Percent_Identity=30.7553956834532, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI133901902, Length=520, Percent_Identity=30.3846153846154, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6322634, Length=551, Percent_Identity=25.9528130671506, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI45550492, Length=575, Percent_Identity=29.5652173913043, Blast_Score=176, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 60567; Mature: 60436

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIDPVTLAVLKGRLEQIADEMDATLYRSAFNPIIAEARDACHGLYHAETGDTLVQGTK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCHHHCCCC
GLPIFVGAMAFAVRAVIEKVARDGDLQPGDSFLFNDPYAGGTHLNDFRLVRPIFRGGKLY
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEE
CWLASVGHWLDIGGNVPGGFNARATESFQEGVRIPPVKLFKAGVLNHDIIEILSANSRVP
EECCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHCCCCCCC
VSNYGDLNGQLNALDLGERRLAELLDAYGENIVAQAFDAFSDRAEAMMRAAIRALPDGIY
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SFEDYLDNDGITPDRLTIALDLTVDGEKMTLDFSRSSAPCAGPLNIAYSTAAACCYVALK
HHHHHHCCCCCCCCEEEEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
HVFTDVPANAGCLRPITFVIPETTLLGVKPPKPVGGYTETILRVIGVVFGALAKADPARA
HHHHCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
TAAPFGTINALSLAGHRPDGSRWVMFSFFGGGLGGNPESDGLSHANNPISMATIPPAEIL
CCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHH
EAAYPVLFTQWALRPDSAGAGAHRGGLGAVYEIEPLTDADVFLLGERGIYPPFGVAGGTP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCC
AALNVFSWETEDGERSPPLASKVTDVKVRAGQRVRLETPGGGGYGDPKDRKREDVERDVR
CEEEEEEECCCCCCCCCCHHHHCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
QGLVSVEAARTLYGVEITPDTTIPAQGAAA
HHHHHHHHHHHEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TAIDPVTLAVLKGRLEQIADEMDATLYRSAFNPIIAEARDACHGLYHAETGDTLVQGTK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCHHHCCCC
GLPIFVGAMAFAVRAVIEKVARDGDLQPGDSFLFNDPYAGGTHLNDFRLVRPIFRGGKLY
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEE
CWLASVGHWLDIGGNVPGGFNARATESFQEGVRIPPVKLFKAGVLNHDIIEILSANSRVP
EECCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHCCCCCCC
VSNYGDLNGQLNALDLGERRLAELLDAYGENIVAQAFDAFSDRAEAMMRAAIRALPDGIY
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SFEDYLDNDGITPDRLTIALDLTVDGEKMTLDFSRSSAPCAGPLNIAYSTAAACCYVALK
HHHHHHCCCCCCCCEEEEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
HVFTDVPANAGCLRPITFVIPETTLLGVKPPKPVGGYTETILRVIGVVFGALAKADPARA
HHHHCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
TAAPFGTINALSLAGHRPDGSRWVMFSFFGGGLGGNPESDGLSHANNPISMATIPPAEIL
CCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHH
EAAYPVLFTQWALRPDSAGAGAHRGGLGAVYEIEPLTDADVFLLGERGIYPPFGVAGGTP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCC
AALNVFSWETEDGERSPPLASKVTDVKVRAGQRVRLETPGGGGYGDPKDRKREDVERDVR
CEEEEEEECCCCCCCCCCHHHHCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
QGLVSVEAARTLYGVEITPDTTIPAQGAAA
HHHHHHHHHHHEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]