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The map label for this gene is 158423741

Identifier: 158423741

GI number: 158423741

Start: 2434585

End: 2436666

Strand: Direct

Name: 158423741

Synonym: AZC_2117

Alternate gene names: NA

Gene position: 2434585-2436666 (Clockwise)

Preceding gene: 158423740

Following gene: 158423742

Centisome position: 45.34

GC content: 70.03

Gene sequence:

>2082_bases
ATGAACGCCCATACCGCAACCCCTGAGGCCAAGCCCGCGCCGGTGGTCGGCGTGGATGTGGGCGGCACCTTCACCGACCT
CTTCTTCTTCGATGCCGCCGCCGGCCGCTTCCGCACCGCCAAGGTGCCGTCCAATCGCGGCGACGAGGCCGTGGGCTTCC
TGGAAGGGCTGAAGACCTTCGGCCCGGTGGCCCAGCTCGGCTCCATCGTCCACGGCACCACGGTGGGCACCAATGCTCTT
CTGGAGCGCAAGGGCGCGCGCACGGCGCTCATCACCACGCGCGGCTTCCGCGATGTGCTGGAGATGCGCCGCCGCGACCG
CCTGCACACGTGGGGCCTATGGGGCGATTTCGTGCCCGTCATTCCCCGCGACATGCGCTTCGAGGTGAGCGAGCGCGTGC
TGGCGGACGGCTCCGTGCGCACGGCCCTCGATATCGAGGAAGTAAAGGCGGCCACCAAGGCGGCGTTGGCGCAGGGCGCG
GAGGCGATCGCCATCGTCTTCATCAATGCCTATGCCAATCCCGCACATGAGCTGGCGGCTCTGGAGGCGGTCCGGGCCCT
GTGGCCGAACGAGAACATCGCCTGCTCGGCGCAGATCCTGCCCGAGATCCGCGAGTTCGAGCGCACCTCCACCACGGCAC
TCAATGCCTATCTCCAGCCGGTGGTGGGCAGCTATCTGAAGAAGCTCGACGACGCGCTGGTGGGCGAGGGCTTCACGGGT
CGCTTCCACATCGTGCAGTCGAGCGGCGGCGTCATGTCCACCGTCACCGCCCGCAAGCTGCCGGTGCGCACCGCGCTCTC
CGGCCCTGCGGCGGGCGTCATCGCGGCGGCGGCCATTGCGGAAGCCGCGGGCTATCCGGATATCATCACTGGCGATCTCG
GGGGCACCTCGTTTGACGTGTCGCTGGTGGCCGGCGGCAAGACGGCGCTGGCGGCACAGACCACCATCGACTTCGGCCTC
GTCATCCGCACGCCGATGATCGAGATCACCACCATCGGCGCCGGCGGCGGCTCCATCGCTTATGTGGATGCCGGCGGCAT
GTTGCAGGTGGGGCCTGAGAGCGCCGGCTCCCGGCCCGGCCCGGTGGCCTATGGGCAGGGCAACACCCGCCCGACGCTCA
CCGATGCCAACATCGTGCTCGGCCGCATCAATGCGGAGCGGCCCATCGGCGGCAAGCTGGCGCGGCTCGACGTGGAGGCG
GCGAAGGCGGCCATTGACACTCATGTGGCCAAGCCCCTCGGCCTCGGCGTCATGGAAGCGGCGGAAGCCATCGTCCGCAT
CGCCGACGGGCGGATGGCGGGCGCCATCCGCCTCGTCTCCATCGAGCGCGGGCATGATCCGGCGACCTTCGCGGCCGTGC
CCTTCGGTGGCGGCGGTGCACTCCATGCGGGCGCGCTCATCAAGGATGTGGGCCTCAAGGCGGCGCTGGTGCCGCGCTAT
CCGGGCGTCACCTCGGCGCTGGGCTGTGTGATCGCCGACATCCGCCACGATCAGGTGCAGACGGTGAATCTCACCGTGGA
TGCCCTCGATCCCGTGGCGCTCGACGCCCGCATGGTGGAGGAAGCCGCCGCCGCCCGCGCGGTGGTGGAGGCCGCAGGCC
TTGCGGTGGAGCGCATCGACACCGTGTTCGAGCTGGACATGCACTATGTCGGCCAGACGCACACGGTCTCCGTGCCGCTG
CCCGTCGAGGTGGAGAACGGCACCACGGGCATCGACCGGGCGACCATCGCGACCGCTTTCGATGCCGCCTATCAGGCCTC
CTTCAGCCGCCTGCTGCCCGGCGTGCCGGCCAAGATCGTGAACCTGCGCACCGCCGCCATCGGCCGTCGTCCGCACTTCG
ATCTCAAGGCGTTGGCGCCGGAGGCCGGGGCGACGGTGGACGGCGCCAGGCGCGGTTCGCGGCCGGTCTGGTTCGCCGGA
GCCTGGCACGAGGCGCAGGTCTTCGCCCGTCTCGAACTGCCGGTGGGCGCGACCATTCCCGGTCCCGCCGTTCTGGAGCA
GCCCGACGCCACGACGCTGGTCGACCCCGATCTCGTCGCTCGCGTCGATGCGCTGGGCAACGTCATCGTGGAGCGCGCGT
GA

Upstream 100 bases:

>100_bases
GCGATGTCCGGCAGGGCCTCGTGAGCGTTGAAGCCGCCCGCACCCTCTATGGCGTCGAGATCACGCCGGACACCACCATT
CCGGCGCAGGGAGCAGCCGC

Downstream 100 bases:

>100_bases
TGCACGAAGCCATCCCGTTCTCACAGACGGCGCTGGTGCTCGTCGATCTCCAGAACGACTTCATCGACCCGAAGGGCGCC
TATGGAAGGGCGGGGCAGGG

Product: hydantoin utilization protein A

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MNAHTATPEAKPAPVVGVDVGGTFTDLFFFDAAAGRFRTAKVPSNRGDEAVGFLEGLKTFGPVAQLGSIVHGTTVGTNAL
LERKGARTALITTRGFRDVLEMRRRDRLHTWGLWGDFVPVIPRDMRFEVSERVLADGSVRTALDIEEVKAATKAALAQGA
EAIAIVFINAYANPAHELAALEAVRALWPNENIACSAQILPEIREFERTSTTALNAYLQPVVGSYLKKLDDALVGEGFTG
RFHIVQSSGGVMSTVTARKLPVRTALSGPAAGVIAAAAIAEAAGYPDIITGDLGGTSFDVSLVAGGKTALAAQTTIDFGL
VIRTPMIEITTIGAGGGSIAYVDAGGMLQVGPESAGSRPGPVAYGQGNTRPTLTDANIVLGRINAERPIGGKLARLDVEA
AKAAIDTHVAKPLGLGVMEAAEAIVRIADGRMAGAIRLVSIERGHDPATFAAVPFGGGGALHAGALIKDVGLKAALVPRY
PGVTSALGCVIADIRHDQVQTVNLTVDALDPVALDARMVEEAAAARAVVEAAGLAVERIDTVFELDMHYVGQTHTVSVPL
PVEVENGTTGIDRATIATAFDAAYQASFSRLLPGVPAKIVNLRTAAIGRRPHFDLKALAPEAGATVDGARRGSRPVWFAG
AWHEAQVFARLELPVGATIPGPAVLEQPDATTLVDPDLVARVDALGNVIVERA

Sequences:

>Translated_693_residues
MNAHTATPEAKPAPVVGVDVGGTFTDLFFFDAAAGRFRTAKVPSNRGDEAVGFLEGLKTFGPVAQLGSIVHGTTVGTNAL
LERKGARTALITTRGFRDVLEMRRRDRLHTWGLWGDFVPVIPRDMRFEVSERVLADGSVRTALDIEEVKAATKAALAQGA
EAIAIVFINAYANPAHELAALEAVRALWPNENIACSAQILPEIREFERTSTTALNAYLQPVVGSYLKKLDDALVGEGFTG
RFHIVQSSGGVMSTVTARKLPVRTALSGPAAGVIAAAAIAEAAGYPDIITGDLGGTSFDVSLVAGGKTALAAQTTIDFGL
VIRTPMIEITTIGAGGGSIAYVDAGGMLQVGPESAGSRPGPVAYGQGNTRPTLTDANIVLGRINAERPIGGKLARLDVEA
AKAAIDTHVAKPLGLGVMEAAEAIVRIADGRMAGAIRLVSIERGHDPATFAAVPFGGGGALHAGALIKDVGLKAALVPRY
PGVTSALGCVIADIRHDQVQTVNLTVDALDPVALDARMVEEAAAARAVVEAAGLAVERIDTVFELDMHYVGQTHTVSVPL
PVEVENGTTGIDRATIATAFDAAYQASFSRLLPGVPAKIVNLRTAAIGRRPHFDLKALAPEAGATVDGARRGSRPVWFAG
AWHEAQVFARLELPVGATIPGPAVLEQPDATTLVDPDLVARVDALGNVIVERA
>Mature_693_residues
MNAHTATPEAKPAPVVGVDVGGTFTDLFFFDAAAGRFRTAKVPSNRGDEAVGFLEGLKTFGPVAQLGSIVHGTTVGTNAL
LERKGARTALITTRGFRDVLEMRRRDRLHTWGLWGDFVPVIPRDMRFEVSERVLADGSVRTALDIEEVKAATKAALAQGA
EAIAIVFINAYANPAHELAALEAVRALWPNENIACSAQILPEIREFERTSTTALNAYLQPVVGSYLKKLDDALVGEGFTG
RFHIVQSSGGVMSTVTARKLPVRTALSGPAAGVIAAAAIAEAAGYPDIITGDLGGTSFDVSLVAGGKTALAAQTTIDFGL
VIRTPMIEITTIGAGGGSIAYVDAGGMLQVGPESAGSRPGPVAYGQGNTRPTLTDANIVLGRINAERPIGGKLARLDVEA
AKAAIDTHVAKPLGLGVMEAAEAIVRIADGRMAGAIRLVSIERGHDPATFAAVPFGGGGALHAGALIKDVGLKAALVPRY
PGVTSALGCVIADIRHDQVQTVNLTVDALDPVALDARMVEEAAAARAVVEAAGLAVERIDTVFELDMHYVGQTHTVSVPL
PVEVENGTTGIDRATIATAFDAAYQASFSRLLPGVPAKIVNLRTAAIGRRPHFDLKALAPEAGATVDGARRGSRPVWFAG
AWHEAQVFARLELPVGATIPGPAVLEQPDATTLVDPDLVARVDALGNVIVERA

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=732, Percent_Identity=29.5081967213115, Blast_Score=223, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI133901900, Length=712, Percent_Identity=25.561797752809, Blast_Score=179, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6322634, Length=751, Percent_Identity=25.965379494008, Blast_Score=194, Evalue=5e-50,
Organism=Drosophila melanogaster, GI45550492, Length=741, Percent_Identity=28.3400809716599, Blast_Score=205, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 72116; Mature: 72116

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAHTATPEAKPAPVVGVDVGGTFTDLFFFDAAAGRFRTAKVPSNRGDEAVGFLEGLKTF
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHH
GPVAQLGSIVHGTTVGTNALLERKGARTALITTRGFRDVLEMRRRDRLHTWGLWGDFVPV
CCHHHHCCHHCCCCCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEECCCCCCCCCC
IPRDMRFEVSERVLADGSVRTALDIEEVKAATKAALAQGAEAIAIVFINAYANPAHELAA
CCCCCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHH
LEAVRALWPNENIACSAQILPEIREFERTSTTALNAYLQPVVGSYLKKLDDALVGEGFTG
HHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RFHIVQSSGGVMSTVTARKLPVRTALSGPAAGVIAAAAIAEAAGYPDIITGDLGGTSFDV
EEEEEECCCCEEEEEHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEE
SLVAGGKTALAAQTTIDFGLVIRTPMIEITTIGAGGGSIAYVDAGGMLQVGPESAGSRPG
EEEECCCEEEEEEEEEEEEEEEECCEEEEEEEECCCCEEEEEECCCEEEECCCCCCCCCC
PVAYGQGNTRPTLTDANIVLGRINAERPIGGKLARLDVEAAKAAIDTHVAKPLGLGVMEA
CEEECCCCCCCEEECCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCHHCCHHHHH
AEAIVRIADGRMAGAIRLVSIERGHDPATFAAVPFGGGGALHAGALIKDVGLKAALVPRY
HHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCC
PGVTSALGCVIADIRHDQVQTVNLTVDALDPVALDARMVEEAAAARAVVEAAGLAVERID
CCHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVFELDMHYVGQTHTVSVPLPVEVENGTTGIDRATIATAFDAAYQASFSRLLPGVPAKIV
HHHHHHHHHCCCEEEEEECEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
NLRTAAIGRRPHFDLKALAPEAGATVDGARRGSRPVWFAGAWHEAQVFARLELPVGATIP
EEHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCC
GPAVLEQPDATTLVDPDLVARVDALGNVIVERA
CCHHCCCCCCCEEECHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNAHTATPEAKPAPVVGVDVGGTFTDLFFFDAAAGRFRTAKVPSNRGDEAVGFLEGLKTF
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHH
GPVAQLGSIVHGTTVGTNALLERKGARTALITTRGFRDVLEMRRRDRLHTWGLWGDFVPV
CCHHHHCCHHCCCCCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEECCCCCCCCCC
IPRDMRFEVSERVLADGSVRTALDIEEVKAATKAALAQGAEAIAIVFINAYANPAHELAA
CCCCCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHH
LEAVRALWPNENIACSAQILPEIREFERTSTTALNAYLQPVVGSYLKKLDDALVGEGFTG
HHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RFHIVQSSGGVMSTVTARKLPVRTALSGPAAGVIAAAAIAEAAGYPDIITGDLGGTSFDV
EEEEEECCCCEEEEEHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEE
SLVAGGKTALAAQTTIDFGLVIRTPMIEITTIGAGGGSIAYVDAGGMLQVGPESAGSRPG
EEEECCCEEEEEEEEEEEEEEEECCEEEEEEEECCCCEEEEEECCCEEEECCCCCCCCCC
PVAYGQGNTRPTLTDANIVLGRINAERPIGGKLARLDVEAAKAAIDTHVAKPLGLGVMEA
CEEECCCCCCCEEECCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCHHCCHHHHH
AEAIVRIADGRMAGAIRLVSIERGHDPATFAAVPFGGGGALHAGALIKDVGLKAALVPRY
HHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCC
PGVTSALGCVIADIRHDQVQTVNLTVDALDPVALDARMVEEAAAARAVVEAAGLAVERID
CCHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVFELDMHYVGQTHTVSVPLPVEVENGTTGIDRATIATAFDAAYQASFSRLLPGVPAKIV
HHHHHHHHHCCCEEEEEECEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
NLRTAAIGRRPHFDLKALAPEAGATVDGARRGSRPVWFAGAWHEAQVFARLELPVGATIP
EEHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCC
GPAVLEQPDATTLVDPDLVARVDALGNVIVERA
CCHHCCCCCCCEEECHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]