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The map label for this gene is qor [H]

Identifier: 158423623

GI number: 158423623

Start: 2304946

End: 2305920

Strand: Direct

Name: qor [H]

Synonym: AZC_1999

Alternate gene names: 158423623

Gene position: 2304946-2305920 (Clockwise)

Preceding gene: 158423621

Following gene: 158423624

Centisome position: 42.92

GC content: 65.54

Gene sequence:

>975_bases
ATGGTCGGGGCGATCCGAATTCATCACACGGGCGGGCCGGAGGTGATGAAGTTCGAGCAGGTGGACCTGCCGCCGCCCGG
TCCCGGTGAGGTGCGCGTTCGCCACACCGCCATCGGCCTCAATTACATCGACACCTATTTCCGCTCCGGCCTCTACAAGG
CGCCGGCGCTGCCCTTCACCCCCGGCAATGAGGGGGCGGGCGAGGTCGAGGCGGTGGGTCCGCACGTCGAGGGTTTCCAC
GCCGGGGACCGCGTCGCTTATGCAACGTCGCTCGGCTCCTATGCGGAAGCGCGCAACGTGCCCGCCAACGTTCTCGTGCA
TGTGCCCGCCGCCATCGACGACCGCACCGCCGCGGCCATGATGCTGAAGGGTATGACGGCGCAATATCTGGTGAAGCACA
CCCATGCGGTGAAGCCGGGGGATGTCATCCTCGTGCAGGCGGCGGCCGGCGGCGTCGGACTGCTGCTCTGCCAGTGGGCC
CATGCGCTGGGTGCCACCGTGATCGGCACCGTCGGATCGAAGGCGAAGGCGGAACTCGCCCTCGCCAATGGCGCGGACCA
TGTAATCCTCTACAAGGACGAGGATTTCGTGCACCGGGTGAAGGAGATCACCTCCGGCAAGATGTGCGATGTGGTCTATG
ATGGCGTGGGGCAGGCGACCTATCCCGCCTCGCTCGACTGCCTGAAGCCCTTCGGCTTGTGGGTGAGCTTCGGCAACGCC
TCGGGCGCGATCAACAATTTCGACCTGCTGAGCCTGTCCCAGAAGGGCTCGCTCTATGCCACGCGGCCGACCCTCTTCAC
CCACACCAGCACCCGCGAGAAGCTCGTGGCGACGGCCAACGATCTCTTCGAGGCGGTCCTGACCGGCGCGCTCAAGATTC
CGGTGCATCAGACCTATGCGCTGAAGGATGCCGCCAAGGCCCACAAGGACCTCGAAAGCCGCGCCACCACGGGGTCAACA
CTTCTTCTACCCTGA

Upstream 100 bases:

>100_bases
TCGTCTCAGCACGCCGCCTGTGCACAGGGCTTTGGCAGGCGCCTTGCCCGGAACTTCAACGCCCCTATGATCGCGGGCGT
TTCAAGCGCGGGAGGCGGAA

Downstream 100 bases:

>100_bases
TCGCAGGTGGTGCGAGGCATTCGCAAAAAAGTCATCTGCGACTTGCGCCAAGGTGGCGCCTGCATGATATGAGCCGGGCT
TGACTAATCACGGCGGCCCG

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MVGAIRIHHTGGPEVMKFEQVDLPPPGPGEVRVRHTAIGLNYIDTYFRSGLYKAPALPFTPGNEGAGEVEAVGPHVEGFH
AGDRVAYATSLGSYAEARNVPANVLVHVPAAIDDRTAAAMMLKGMTAQYLVKHTHAVKPGDVILVQAAAGGVGLLLCQWA
HALGATVIGTVGSKAKAELALANGADHVILYKDEDFVHRVKEITSGKMCDVVYDGVGQATYPASLDCLKPFGLWVSFGNA
SGAINNFDLLSLSQKGSLYATRPTLFTHTSTREKLVATANDLFEAVLTGALKIPVHQTYALKDAAKAHKDLESRATTGST
LLLP

Sequences:

>Translated_324_residues
MVGAIRIHHTGGPEVMKFEQVDLPPPGPGEVRVRHTAIGLNYIDTYFRSGLYKAPALPFTPGNEGAGEVEAVGPHVEGFH
AGDRVAYATSLGSYAEARNVPANVLVHVPAAIDDRTAAAMMLKGMTAQYLVKHTHAVKPGDVILVQAAAGGVGLLLCQWA
HALGATVIGTVGSKAKAELALANGADHVILYKDEDFVHRVKEITSGKMCDVVYDGVGQATYPASLDCLKPFGLWVSFGNA
SGAINNFDLLSLSQKGSLYATRPTLFTHTSTREKLVATANDLFEAVLTGALKIPVHQTYALKDAAKAHKDLESRATTGST
LLLP
>Mature_324_residues
MVGAIRIHHTGGPEVMKFEQVDLPPPGPGEVRVRHTAIGLNYIDTYFRSGLYKAPALPFTPGNEGAGEVEAVGPHVEGFH
AGDRVAYATSLGSYAEARNVPANVLVHVPAAIDDRTAAAMMLKGMTAQYLVKHTHAVKPGDVILVQAAAGGVGLLLCQWA
HALGATVIGTVGSKAKAELALANGADHVILYKDEDFVHRVKEITSGKMCDVVYDGVGQATYPASLDCLKPFGLWVSFGNA
SGAINNFDLLSLSQKGSLYATRPTLFTHTSTREKLVATANDLFEAVLTGALKIPVHQTYALKDAAKAHKDLESRATTGST
LLLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=31.1926605504587, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=31.1926605504587, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=29.9694189602446, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=31.7307692307692, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=29.0909090909091, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=29.0909090909091, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI24308257, Length=240, Percent_Identity=30.8333333333333, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI28557745, Length=223, Percent_Identity=34.0807174887892, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI197927207, Length=190, Percent_Identity=28.9473684210526, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI67078404, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI47519420, Length=250, Percent_Identity=30.4, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI67078406, Length=141, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=51.3761467889908, Blast_Score=319, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17507255, Length=306, Percent_Identity=28.7581699346405, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319520, Length=322, Percent_Identity=34.7826086956522, Blast_Score=182, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6319621, Length=354, Percent_Identity=25.9887005649718, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=305, Percent_Identity=25.9016393442623, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=306, Percent_Identity=26.797385620915, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34246; Mature: 34246

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGAIRIHHTGGPEVMKFEQVDLPPPGPGEVRVRHTAIGLNYIDTYFRSGLYKAPALPFT
CCCEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEEEECHHHHHHHHHCCCCCCCCCCCC
PGNEGAGEVEAVGPHVEGFHAGDRVAYATSLGSYAEARNVPANVLVHVPAAIDDRTAAAM
CCCCCCCCEEEECCCCCCCCCCCCEEEEHHHCCHHHHCCCCCEEEEECCCCCCCHHHHHH
MLKGMTAQYLVKHTHAVKPGDVILVQAAAGGVGLLLCQWAHALGATVIGTVGSKAKAELA
HHHCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCHHEEECCCCCCEEEEE
LANGADHVILYKDEDFVHRVKEITSGKMCDVVYDGVGQATYPASLDCLKPFGLWVSFGNA
EECCCCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCC
SGAINNFDLLSLSQKGSLYATRPTLFTHTSTREKLVATANDLFEAVLTGALKIPVHQTYA
CCCCCCEEEEEECCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHCEEECCCCHHHH
LKDAAKAHKDLESRATTGSTLLLP
HHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MVGAIRIHHTGGPEVMKFEQVDLPPPGPGEVRVRHTAIGLNYIDTYFRSGLYKAPALPFT
CCCEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEEEECHHHHHHHHHCCCCCCCCCCCC
PGNEGAGEVEAVGPHVEGFHAGDRVAYATSLGSYAEARNVPANVLVHVPAAIDDRTAAAM
CCCCCCCCEEEECCCCCCCCCCCCEEEEHHHCCHHHHCCCCCEEEEECCCCCCCHHHHHH
MLKGMTAQYLVKHTHAVKPGDVILVQAAAGGVGLLLCQWAHALGATVIGTVGSKAKAELA
HHHCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCHHEEECCCCCCEEEEE
LANGADHVILYKDEDFVHRVKEITSGKMCDVVYDGVGQATYPASLDCLKPFGLWVSFGNA
EECCCCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCC
SGAINNFDLLSLSQKGSLYATRPTLFTHTSTREKLVATANDLFEAVLTGALKIPVHQTYA
CCCCCCEEEEEECCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHCEEECCCCHHHH
LKDAAKAHKDLESRATTGSTLLLP
HHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]