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The map label for this gene is yrbG [H]

Identifier: 157963424

GI number: 157963424

Start: 4402573

End: 4403532

Strand: Direct

Name: yrbG [H]

Synonym: Spea_3610

Alternate gene names: 157963424

Gene position: 4402573-4403532 (Clockwise)

Preceding gene: 157963413

Following gene: 157963425

Centisome position: 85.08

GC content: 46.25

Gene sequence:

>960_bases
ATGTTATTTAATATTTTTATGTTAGTGGCAGGCTTAGGGGCTCTCGTTTGGAGCGCTGATAAGTTTGTTTACGGTGCAGC
CGCTTTTGCTCGTAACCTTGGCTTACCACCCATGTTAATCGGTTTAACGATTGTCGCCATGGGTAGCTCTGCTCCCGAGA
TGTTTGTTGCGGCCACAGCATCCCTCGAAGGCATGACCGATACCGCAATCGGCAATGTGCTGGGCTCTAACATAGCAAAC
ATCACATTAATCTTAGGTATTACAGCCTTACTCGGAGCGATTTCTGTCAGTTCACAGACGCTGAAACGTGAAATTCCAAT
GATGCTGGTAGCCACCGTAATTGTGGGTTACTTCCTACATGATGGTTTCTTAACGCGTATCGAAGGTGTCAGCTTATTAG
TGATGTTCATTGGCTTAATGGGCTATCTGATTTGGCACGGACTTCATAGTAAAAACCGTGACGCTTTAGCCGTAGATGCC
GAAAATGAGATCCCTGCCGATGTGCCTACAGCTAAAGCGGTTTTATGGCTTGTAGTCGGCATGGTATTGTTACCATTATC
GGCAGATTGGATGGTCCAAGGCGCAGTAGGGATAGCAAAGGCGTATCACCTATCGGATCTAGTGATCGGCCTAACTATTA
TTGCCGTGGGTACCAGCTTACCAGAGCTTGCCGCTTGTGTTGCCGGAGTCTTAAAAAAAGAAGACGACCTTGCGATTGGT
AACATAGTTGGTTCAAACTTATTCAATATTTTAGCGGTACTTGCGATACCTGGCATCATAGCGCCAGGCGCTGTCGATGC
GGCGGCGAGTACTCGAGACTTTTATATGGTGCTTGCCACGAGCAGTGCACTGGCAATACTTATCTTATTATCAGGCCGTG
CTAGACAGTTAAAACCCTGGCATGGCGTAGTATTACTTATTACATTTATCGCATACCAAGCACTACTTTTCCTATCTTAG

Upstream 100 bases:

>100_bases
ACAGGGGCACAACCAAATCGATACTATCTCGCCTCAATACTTTCATTTTTCTTCAATTACAGCGAAAATAGCCCGCTATA
CCCAAAAATACTAAGAATCG

Downstream 100 bases:

>100_bases
CTGTGGGTGCGGTACGTTAAGCAGAAATTTAAAGAGAGACCAAGAAATGGTAGATGAGAATCAACTACGCCAATGGGGTA
CAAAAGTTATCGATATCGAG

Product: CaCA family Na(+)/Ca(+) antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MLFNIFMLVAGLGALVWSADKFVYGAAAFARNLGLPPMLIGLTIVAMGSSAPEMFVAATASLEGMTDTAIGNVLGSNIAN
ITLILGITALLGAISVSSQTLKREIPMMLVATVIVGYFLHDGFLTRIEGVSLLVMFIGLMGYLIWHGLHSKNRDALAVDA
ENEIPADVPTAKAVLWLVVGMVLLPLSADWMVQGAVGIAKAYHLSDLVIGLTIIAVGTSLPELAACVAGVLKKEDDLAIG
NIVGSNLFNILAVLAIPGIIAPGAVDAAASTRDFYMVLATSSALAILILLSGRARQLKPWHGVVLLITFIAYQALLFLS

Sequences:

>Translated_319_residues
MLFNIFMLVAGLGALVWSADKFVYGAAAFARNLGLPPMLIGLTIVAMGSSAPEMFVAATASLEGMTDTAIGNVLGSNIAN
ITLILGITALLGAISVSSQTLKREIPMMLVATVIVGYFLHDGFLTRIEGVSLLVMFIGLMGYLIWHGLHSKNRDALAVDA
ENEIPADVPTAKAVLWLVVGMVLLPLSADWMVQGAVGIAKAYHLSDLVIGLTIIAVGTSLPELAACVAGVLKKEDDLAIG
NIVGSNLFNILAVLAIPGIIAPGAVDAAASTRDFYMVLATSSALAILILLSGRARQLKPWHGVVLLITFIAYQALLFLS
>Mature_319_residues
MLFNIFMLVAGLGALVWSADKFVYGAAAFARNLGLPPMLIGLTIVAMGSSAPEMFVAATASLEGMTDTAIGNVLGSNIAN
ITLILGITALLGAISVSSQTLKREIPMMLVATVIVGYFLHDGFLTRIEGVSLLVMFIGLMGYLIWHGLHSKNRDALAVDA
ENEIPADVPTAKAVLWLVVGMVLLPLSADWMVQGAVGIAKAYHLSDLVIGLTIIAVGTSLPELAACVAGVLKKEDDLAIG
NIVGSNLFNILAVLAIPGIIAPGAVDAAASTRDFYMVLATSSALAILILLSGRARQLKPWHGVVLLITFIAYQALLFLS

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI300797299, Length=163, Percent_Identity=33.1288343558282, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI29788987, Length=163, Percent_Identity=33.1288343558282, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI300797277, Length=163, Percent_Identity=33.1288343558282, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789587, Length=305, Percent_Identity=40, Blast_Score=201, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 33381; Mature: 33381

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFNIFMLVAGLGALVWSADKFVYGAAAFARNLGLPPMLIGLTIVAMGSSAPEMFVAATA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHEEEHH
SLEGMTDTAIGNVLGSNIANITLILGITALLGAISVSSQTLKREIPMMLVATVIVGYFLH
HCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGFLTRIEGVSLLVMFIGLMGYLIWHGLHSKNRDALAVDAENEIPADVPTAKAVLWLVVG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
MVLLPLSADWMVQGAVGIAKAYHLSDLVIGLTIIAVGTSLPELAACVAGVLKKEDDLAIG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHH
NIVGSNLFNILAVLAIPGIIAPGAVDAAASTRDFYMVLATSSALAILILLSGRARQLKPW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCH
HGVVLLITFIAYQALLFLS
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFNIFMLVAGLGALVWSADKFVYGAAAFARNLGLPPMLIGLTIVAMGSSAPEMFVAATA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHEEEHH
SLEGMTDTAIGNVLGSNIANITLILGITALLGAISVSSQTLKREIPMMLVATVIVGYFLH
HCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGFLTRIEGVSLLVMFIGLMGYLIWHGLHSKNRDALAVDAENEIPADVPTAKAVLWLVVG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
MVLLPLSADWMVQGAVGIAKAYHLSDLVIGLTIIAVGTSLPELAACVAGVLKKEDDLAIG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHH
NIVGSNLFNILAVLAIPGIIAPGAVDAAASTRDFYMVLATSSALAILILLSGRARQLKPW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCH
HGVVLLITFIAYQALLFLS
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]