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The map label for this gene is yuxL [H]

Identifier: 157963221

GI number: 157963221

Start: 4161475

End: 4163517

Strand: Direct

Name: yuxL [H]

Synonym: Spea_3407

Alternate gene names: 157963221

Gene position: 4161475-4163517 (Clockwise)

Preceding gene: 157963220

Following gene: 157963223

Centisome position: 80.42

GC content: 47.97

Gene sequence:

>2043_bases
GTGAAGAAAGCCGGGATCCTGCTATTGTGTCTGCTAATGCCGATGGCGACAGCATTTGCAGAACAAACCAAACCGCTTTC
GGTTGATGTGCTGTGGCAACTCAACCGTATAGGCAGTCCAATTATTTCACCGCAGGGCGACAAAATTATCGCTCCTGTTA
CCCAATATGATGTACCTGAAGATAAAGGCTCGACTCAACTTTGGTTATTTGATAAAGACGGCGATAGCCAGCAAGCACTA
ACAGCCAAAGGTATGCGCGCTAGCGAAGCCACCTTCTCACCAGATGGAAAAACGCTGGCGTTTATCAGCAAACGCGATGA
AGATGAAGCAGGCCAGGTTTACCTGCTACCGATGAACGGTCCAGGTGAAGCGCAAAAGCTTACTGATGTGCCAGGTGGCG
TATACGGCATGAAGTGGGTCGGTAAACATATCTACTTTATTAGCCGCATATTCCCGGGTAAGAACTGGGACGAGATGGCT
AAGCAGTTAAAAGCCGACAAAGACACTAAAGTCTCTGCTCACCAATGGACCGAACTGCCTTATTCAAGCTTTGACCACTG
GATTGATGAAGACCGTGAGGCCCATGTATTCCGTATCCCAGCTACAGGCGGCGAGATTGAAGCCATCACTCAGCCGCTGA
GCCAGCAGTTACCACGCTCATCACAAAGCGCCTCAAGCTATGATATTGCGCCAAATGAACAGTGGATTGCCTTTACCGCC
AATGGCTGGGACGCGGCAATGAAAACCCGCGAAGTTGATCCTAAGATTGATATCTTGTTAGCTAAAATTGGCAGCGGCAA
AGCAGAAAACTTAACTCCTGATAACGAAGCGCCAAATAGCAGCCCGCAGTTTAGCCCTAATGGTAAAACCTTGGCCTTTA
CTCAGCAGCTTATTCACGGTTTCTATGCCGATACAACACGCCTAGTATTGATGGATATGAAAAAGCGTCAACCAAAGGTG
ATTAACGACTCTTGGGATCGCTCTGTATCACGCTTTGGTTGGACCAAAGACAGCAAAGGTTTCTACGCCGCAATTGATGA
TGCTGCCACCAGCCGCATTTATCATATTAATGCTAAAAACGGTAAGGTAAAAGCCATTAGCAAAGACACTAACTTTGGTA
AGCCAGTGATGGCTAAAGACGGCACTATCGTGGCGACTAATGACAGCTTCTTATACCCTGCACGCCTTGTGACCATTAAC
CCACGTAACGGTAAAACCACCCGTCTAGATAGCTTTAACGACGATATCCTTGCTGATGTTGATATGGGCACTTATGAGTC
GGTAACCTACAAGGGCTATAACGATCAAGACATTCAGATGTGGGTCCACTACCCACCAGGATTTGATCGCAGCAAGAAGT
ATCCGCTGATGATGCTAATCCACGGTGGCCCACACAATGCAATCTCTGATGGTTTCCACTACCGCTGGAACGCGCAGACA
TTCGCTTCTTGGGGTTACGTCACTGCATGGCCAAACTTCCATGGTTCGAGCGGCTTTGGCCAAGAGTTTGCAGACAGCAT
CAACCCAGACTGGAAGAACAAGTCATTAGAAGACGTGCTTAAGGCGGCTGATTGGTTTGAGCAAAAAGAGTGGATTGACA
GTGAGCGTATGGTGGCTGGCGGCGCGAGCTATGGCGGCTACTTATCCTCAATTATTTTAGGTCAAGAACATCCATTTAAT
GCACTACTGATCCACGCTGCTGTGTATAACATGTACTCGCAAATGTCAGCTGACTTTGCCGTGCATAGCACGCGTTTTGG
TCATTACTGGGAGAAACCAGAGATCTACAAGTCGATCTCTCCACACTACTTTGCTGAGAACTTTAACACCCCAACTTTGG
TGATCCACGGTCAGTTAGATTACCGCGTCCCCGTCGGCCAAGGTTTTGAGCTATTCCGTACTCTGCAGAGCCGTGGTGTT
GAGTCTAAAATGATCTACTTCCCAGACGAGAATCACTGGATCATGAAGCCAAACAACTCTATCTATTGGTACAACCAAGT
AGAAGATTGGATGACCCGCTTTGCCGAGCCAGGCGGACGTTAA

Upstream 100 bases:

>100_bases
TCCTTTATTCAATGTTCATGGCTATACTGGCTCGCCTGCATTTTGCAGCGCTACAACTAATAAAAATAATCAAACAAATT
GCTCCTAAGGAGAACCACTC

Downstream 100 bases:

>100_bases
TCAAGCTTAGTTAAAGTCATTAAACTGCTTAAACTAAAAAGGCTGCCAATTGGCAGCCTTTGTTATTACAGCTAACACCT
AAGCCAATTTAGGACTCATA

Product: peptidase S9 prolyl oligopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MKKAGILLLCLLMPMATAFAEQTKPLSVDVLWQLNRIGSPIISPQGDKIIAPVTQYDVPEDKGSTQLWLFDKDGDSQQAL
TAKGMRASEATFSPDGKTLAFISKRDEDEAGQVYLLPMNGPGEAQKLTDVPGGVYGMKWVGKHIYFISRIFPGKNWDEMA
KQLKADKDTKVSAHQWTELPYSSFDHWIDEDREAHVFRIPATGGEIEAITQPLSQQLPRSSQSASSYDIAPNEQWIAFTA
NGWDAAMKTREVDPKIDILLAKIGSGKAENLTPDNEAPNSSPQFSPNGKTLAFTQQLIHGFYADTTRLVLMDMKKRQPKV
INDSWDRSVSRFGWTKDSKGFYAAIDDAATSRIYHINAKNGKVKAISKDTNFGKPVMAKDGTIVATNDSFLYPARLVTIN
PRNGKTTRLDSFNDDILADVDMGTYESVTYKGYNDQDIQMWVHYPPGFDRSKKYPLMMLIHGGPHNAISDGFHYRWNAQT
FASWGYVTAWPNFHGSSGFGQEFADSINPDWKNKSLEDVLKAADWFEQKEWIDSERMVAGGASYGGYLSSIILGQEHPFN
ALLIHAAVYNMYSQMSADFAVHSTRFGHYWEKPEIYKSISPHYFAENFNTPTLVIHGQLDYRVPVGQGFELFRTLQSRGV
ESKMIYFPDENHWIMKPNNSIYWYNQVEDWMTRFAEPGGR

Sequences:

>Translated_680_residues
MKKAGILLLCLLMPMATAFAEQTKPLSVDVLWQLNRIGSPIISPQGDKIIAPVTQYDVPEDKGSTQLWLFDKDGDSQQAL
TAKGMRASEATFSPDGKTLAFISKRDEDEAGQVYLLPMNGPGEAQKLTDVPGGVYGMKWVGKHIYFISRIFPGKNWDEMA
KQLKADKDTKVSAHQWTELPYSSFDHWIDEDREAHVFRIPATGGEIEAITQPLSQQLPRSSQSASSYDIAPNEQWIAFTA
NGWDAAMKTREVDPKIDILLAKIGSGKAENLTPDNEAPNSSPQFSPNGKTLAFTQQLIHGFYADTTRLVLMDMKKRQPKV
INDSWDRSVSRFGWTKDSKGFYAAIDDAATSRIYHINAKNGKVKAISKDTNFGKPVMAKDGTIVATNDSFLYPARLVTIN
PRNGKTTRLDSFNDDILADVDMGTYESVTYKGYNDQDIQMWVHYPPGFDRSKKYPLMMLIHGGPHNAISDGFHYRWNAQT
FASWGYVTAWPNFHGSSGFGQEFADSINPDWKNKSLEDVLKAADWFEQKEWIDSERMVAGGASYGGYLSSIILGQEHPFN
ALLIHAAVYNMYSQMSADFAVHSTRFGHYWEKPEIYKSISPHYFAENFNTPTLVIHGQLDYRVPVGQGFELFRTLQSRGV
ESKMIYFPDENHWIMKPNNSIYWYNQVEDWMTRFAEPGGR
>Mature_680_residues
MKKAGILLLCLLMPMATAFAEQTKPLSVDVLWQLNRIGSPIISPQGDKIIAPVTQYDVPEDKGSTQLWLFDKDGDSQQAL
TAKGMRASEATFSPDGKTLAFISKRDEDEAGQVYLLPMNGPGEAQKLTDVPGGVYGMKWVGKHIYFISRIFPGKNWDEMA
KQLKADKDTKVSAHQWTELPYSSFDHWIDEDREAHVFRIPATGGEIEAITQPLSQQLPRSSQSASSYDIAPNEQWIAFTA
NGWDAAMKTREVDPKIDILLAKIGSGKAENLTPDNEAPNSSPQFSPNGKTLAFTQQLIHGFYADTTRLVLMDMKKRQPKV
INDSWDRSVSRFGWTKDSKGFYAAIDDAATSRIYHINAKNGKVKAISKDTNFGKPVMAKDGTIVATNDSFLYPARLVTIN
PRNGKTTRLDSFNDDILADVDMGTYESVTYKGYNDQDIQMWVHYPPGFDRSKKYPLMMLIHGGPHNAISDGFHYRWNAQT
FASWGYVTAWPNFHGSSGFGQEFADSINPDWKNKSLEDVLKAADWFEQKEWIDSERMVAGGASYGGYLSSIILGQEHPFN
ALLIHAAVYNMYSQMSADFAVHSTRFGHYWEKPEIYKSISPHYFAENFNTPTLVIHGQLDYRVPVGQGFELFRTLQSRGV
ESKMIYFPDENHWIMKPNNSIYWYNQVEDWMTRFAEPGGR

Specific function: Unknown

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=428, Percent_Identity=24.2990654205607, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI18765694, Length=259, Percent_Identity=25.0965250965251, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI16933540, Length=223, Percent_Identity=28.2511210762332, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17552908, Length=205, Percent_Identity=27.8048780487805, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25149159, Length=234, Percent_Identity=26.0683760683761, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17508019, Length=232, Percent_Identity=25.8620689655172, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17508017, Length=232, Percent_Identity=25.8620689655172, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24582257, Length=230, Percent_Identity=26.0869565217391, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582032, Length=215, Percent_Identity=26.5116279069767, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 76742; Mature: 76742

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAGILLLCLLMPMATAFAEQTKPLSVDVLWQLNRIGSPIISPQGDKIIAPVTQYDVPE
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCCCCCEEEECHHHCCCCC
DKGSTQLWLFDKDGDSQQALTAKGMRASEATFSPDGKTLAFISKRDEDEAGQVYLLPMNG
CCCCEEEEEEECCCCCCHHHHHCCCCCCCCEECCCCCEEEEEECCCCCCCCEEEEEECCC
PGEAQKLTDVPGGVYGMKWVGKHIYFISRIFPGKNWDEMAKQLKADKDTKVSAHQWTELP
CCCCHHHHCCCCCCHHHHHHHHHHEEEEHHCCCCCHHHHHHHHCCCCCCCCCHHHHCCCC
YSSFDHWIDEDREAHVFRIPATGGEIEAITQPLSQQLPRSSQSASSYDIAPNEQWIAFTA
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEE
NGWDAAMKTREVDPKIDILLAKIGSGKAENLTPDNEAPNSSPQFSPNGKTLAFTQQLIHG
CCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHH
FYADTTRLVLMDMKKRQPKVINDSWDRSVSRFGWTKDSKGFYAAIDDAATSRIYHINAKN
HHCCCEEEEEEEHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCC
GKVKAISKDTNFGKPVMAKDGTIVATNDSFLYPARLVTINPRNGKTTRLDSFNDDILADV
CEEEEEECCCCCCCCEEECCCEEEEECCCEECCEEEEEEECCCCCEEECCCCCCCEEEEC
DMGTYESVTYKGYNDQDIQMWVHYPPGFDRSKKYPLMMLIHGGPHNAISDGFHYRWNAQT
CCCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCE
FASWGYVTAWPNFHGSSGFGQEFADSINPDWKNKSLEDVLKAADWFEQKEWIDSERMVAG
EECCCEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEC
GASYGGYLSSIILGQEHPFNALLIHAAVYNMYSQMSADFAVHSTRFGHYWEKPEIYKSIS
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHCC
PHYFAENFNTPTLVIHGQLDYRVPVGQGFELFRTLQSRGVESKMIYFPDENHWIMKPNNS
CCEECCCCCCCEEEEECCEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEECCCCC
IYWYNQVEDWMTRFAEPGGR
EEEECCHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKAGILLLCLLMPMATAFAEQTKPLSVDVLWQLNRIGSPIISPQGDKIIAPVTQYDVPE
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCCCCCEEEECHHHCCCCC
DKGSTQLWLFDKDGDSQQALTAKGMRASEATFSPDGKTLAFISKRDEDEAGQVYLLPMNG
CCCCEEEEEEECCCCCCHHHHHCCCCCCCCEECCCCCEEEEEECCCCCCCCEEEEEECCC
PGEAQKLTDVPGGVYGMKWVGKHIYFISRIFPGKNWDEMAKQLKADKDTKVSAHQWTELP
CCCCHHHHCCCCCCHHHHHHHHHHEEEEHHCCCCCHHHHHHHHCCCCCCCCCHHHHCCCC
YSSFDHWIDEDREAHVFRIPATGGEIEAITQPLSQQLPRSSQSASSYDIAPNEQWIAFTA
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEE
NGWDAAMKTREVDPKIDILLAKIGSGKAENLTPDNEAPNSSPQFSPNGKTLAFTQQLIHG
CCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHH
FYADTTRLVLMDMKKRQPKVINDSWDRSVSRFGWTKDSKGFYAAIDDAATSRIYHINAKN
HHCCCEEEEEEEHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCC
GKVKAISKDTNFGKPVMAKDGTIVATNDSFLYPARLVTINPRNGKTTRLDSFNDDILADV
CEEEEEECCCCCCCCEEECCCEEEEECCCEECCEEEEEEECCCCCEEECCCCCCCEEEEC
DMGTYESVTYKGYNDQDIQMWVHYPPGFDRSKKYPLMMLIHGGPHNAISDGFHYRWNAQT
CCCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCE
FASWGYVTAWPNFHGSSGFGQEFADSINPDWKNKSLEDVLKAADWFEQKEWIDSERMVAG
EECCCEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEC
GASYGGYLSSIILGQEHPFNALLIHAAVYNMYSQMSADFAVHSTRFGHYWEKPEIYKSIS
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHCC
PHYFAENFNTPTLVIHGQLDYRVPVGQGFELFRTLQSRGVESKMIYFPDENHWIMKPNNS
CCEECCCCCCCEEEEECCEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEECCCCC
IYWYNQVEDWMTRFAEPGGR
EEEECCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]