Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 157962705

GI number: 157962705

Start: 3524389

End: 3525189

Strand: Direct

Name: map [H]

Synonym: Spea_2886

Alternate gene names: 157962705

Gene position: 3524389-3525189 (Clockwise)

Preceding gene: 157962687

Following gene: 157962706

Centisome position: 68.11

GC content: 43.82

Gene sequence:

>801_bases
ATGAGTATAGTAATTAAGACTGCTGAAGAGATTGAAAAGATGCGTGCCGCGGGTAAGCTGGCCGCTCAAGTGCTCGAGAT
GATCGCCCCGCACGTAAAAGCAGGCGTAACCACAAACGAGCTTAACGATATTTGTGCCAAATATACCGAAGAGCAGGACG
CGATTTCAGCTCCACTTGATTATCATGGTTTCCCGAAATCTATTTGTACTTCAATCAACAATGTGATCTGTCATGGTATT
CCAAGCGATCGTCCTCTCGTTGATGGCGATATCGTCAATATCGATATCACGGTAATCAAAGATGGTTACCACGGTGACAC
TTCAAAAATGTTCCTTATTGGCGATGTAAACCCAAAGAACGTCCGTCTTTGCCGCATCGCCCAAGAAGCACTTTACACCA
GCATTAAAAAAGTAAAGCCTGGCATGAAACTCGGTGAGATCGGTACCTTGATTGAAAAATTCATCAAGTCGAAGAAGACC
GGCCTTGAGAAGTACAGCATTGTTACCGATTACTGCGGCCATGGTATTGGTGCTGGCTTCCATGAAGAGCCACAAGTTAT
GCACTATAAAAATAATGACAAAACCGTACTTAAAGCTGGCATGTGTTTTACTATCGAGCCGATGATCAATGCCGGTCGTC
ACACTAGTGTTTTAGATAAGAAAGACAACTGGACGGTTACCACTTCTGACGGTAAAAATTCAGCTCAGTGGGAACACACG
CTTTTGGTCACTCAGACTGGCGTAGAAGTGTTAACCTTAAGAGAAGAAGAAAAAGAGCTACCAAGAGTGATTAACCACTA
A

Upstream 100 bases:

>100_bases
TTGAAAAAAAGCACAAATATTTACGTCGTTTTTTGGACAAAATCGTTATATCGAAACACGACTAATTTTAGACATTGAAA
GACATTAAGAGACATTAGAA

Downstream 100 bases:

>100_bases
TTTTCGTTACCTCTTTGTAGGCTAAGTTTAGAAAGGCGTGATGATTCACGCCTTTTTTGTATCTATATATCCTTTAAAAG
AGATTAATCTCCATGCAATT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKAGVTTNELNDICAKYTEEQDAISAPLDYHGFPKSICTSINNVICHGI
PSDRPLVDGDIVNIDITVIKDGYHGDTSKMFLIGDVNPKNVRLCRIAQEALYTSIKKVKPGMKLGEIGTLIEKFIKSKKT
GLEKYSIVTDYCGHGIGAGFHEEPQVMHYKNNDKTVLKAGMCFTIEPMINAGRHTSVLDKKDNWTVTTSDGKNSAQWEHT
LLVTQTGVEVLTLREEEKELPRVINH

Sequences:

>Translated_266_residues
MSIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKAGVTTNELNDICAKYTEEQDAISAPLDYHGFPKSICTSINNVICHGI
PSDRPLVDGDIVNIDITVIKDGYHGDTSKMFLIGDVNPKNVRLCRIAQEALYTSIKKVKPGMKLGEIGTLIEKFIKSKKT
GLEKYSIVTDYCGHGIGAGFHEEPQVMHYKNNDKTVLKAGMCFTIEPMINAGRHTSVLDKKDNWTVTTSDGKNSAQWEHT
LLVTQTGVEVLTLREEEKELPRVINH
>Mature_265_residues
SIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKAGVTTNELNDICAKYTEEQDAISAPLDYHGFPKSICTSINNVICHGIP
SDRPLVDGDIVNIDITVIKDGYHGDTSKMFLIGDVNPKNVRLCRIAQEALYTSIKKVKPGMKLGEIGTLIEKFIKSKKTG
LEKYSIVTDYCGHGIGAGFHEEPQVMHYKNNDKTVLKAGMCFTIEPMINAGRHTSVLDKKDNWTVTTSDGKNSAQWEHTL
LVTQTGVEVLTLREEEKELPRVINH

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=253, Percent_Identity=45.8498023715415, Blast_Score=222, Evalue=3e-58,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=40.4761904761905, Blast_Score=200, Evalue=1e-51,
Organism=Escherichia coli, GI1786364, Length=269, Percent_Identity=58.364312267658, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1788728, Length=256, Percent_Identity=25.78125, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71996291, Length=256, Percent_Identity=46.875, Blast_Score=217, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6323273, Length=258, Percent_Identity=44.1860465116279, Blast_Score=218, Evalue=1e-57,
Organism=Drosophila melanogaster, GI21355531, Length=258, Percent_Identity=45.3488372093023, Blast_Score=231, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=41.7670682730924, Blast_Score=211, Evalue=3e-55,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29433; Mature: 29302

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKAGVTTNELNDICAKYTEEQDAISAPLD
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHCCCCC
YHGFPKSICTSINNVICHGIPSDRPLVDGDIVNIDITVIKDGYHGDTSKMFLIGDVNPKN
CCCCCHHHHHHHHHHEEECCCCCCCEECCEEEEEEEEEEECCCCCCCCCEEEEECCCCCC
VRLCRIAQEALYTSIKKVKPGMKLGEIGTLIEKFIKSKKTGLEKYSIVTDYCGHGIGAGF
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
HEEPQVMHYKNNDKTVLKAGMCFTIEPMINAGRHTSVLDKKDNWTVTTSDGKNSAQWEHT
CCCCCEEEEECCCCEEEECCCEEEEEHHHCCCCCCCEEECCCCEEEEECCCCCCCCEEEE
LLVTQTGVEVLTLREEEKELPRVINH
EEEEECCCEEEEECHHHHHHHHHHCC
>Mature Secondary Structure 
SIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKAGVTTNELNDICAKYTEEQDAISAPLD
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHCCCCC
YHGFPKSICTSINNVICHGIPSDRPLVDGDIVNIDITVIKDGYHGDTSKMFLIGDVNPKN
CCCCCHHHHHHHHHHEEECCCCCCCEECCEEEEEEEEEEECCCCCCCCCEEEEECCCCCC
VRLCRIAQEALYTSIKKVKPGMKLGEIGTLIEKFIKSKKTGLEKYSIVTDYCGHGIGAGF
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
HEEPQVMHYKNNDKTVLKAGMCFTIEPMINAGRHTSVLDKKDNWTVTTSDGKNSAQWEHT
CCCCCEEEEECCCCEEEECCCEEEEEHHHCCCCCCCEEECCCCEEEEECCCCCCCCEEEE
LLVTQTGVEVLTLREEEKELPRVINH
EEEEECCCEEEEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]