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The map label for this gene is yegE [C]

Identifier: 157962687

GI number: 157962687

Start: 3503187

End: 3504068

Strand: Direct

Name: yegE [C]

Synonym: Spea_2868

Alternate gene names: 157962687

Gene position: 3503187-3504068 (Clockwise)

Preceding gene: 157962684

Following gene: 157962705

Centisome position: 67.7

GC content: 41.72

Gene sequence:

>882_bases
ATGGAACTTGGCTTAGCAACAGAGTCCTTCCCTATCAAGTATCGCCAGCAGACTGAGATAGGAATGTCGACGTCGTTGGA
TATCGATCTTGTCAATATTATCCAACAACTGCATCAACACTTAGATCCAAGGACAGTGTTTGCCTGCTTTGGCCAGATAA
TGGGACAACATTTGCCGCTTTACGGTGTACGTCTGACTTATAAACAATATCAGTTTCATTGGGGTCAAACATACGGCTAT
GCCTTCGAGCAAAAACTGACCTTTTCCGACCAGCAAGTTACCATTAACTATAATCTAAAAGCTGCCTTAGTGCCGTCGCA
AACCTTGATGTTAAATCAGCTTAAAGACCTAGTGTTACAACCGCTTATTAACGCCATTCAATATCAAGAAATGTCACAGC
AAGCCATGTATGATGCGCTCACTAAGCTAGGTAATCGTCATTACTACCAACAATCTCTAAAAAAGGAGATTGCCCGAGCC
AAACGTAACCAAAGCAGCTTTTCTCTTATCGTCTTAGATTTAGACAATTTTAAACAACTTAATGACGATTTTGGGCATCA
ATTAGGTGACAGCGCCTTAGTTGAATTTGCCGACATGCTCAATGCCACGATAAGAGACACTGACCAAGCATTTAGAATTG
GTGGTGATGAGTTTACTTTGCTAGTACAAGCCGATGTTGATGAGGCTCGAGTTTTATGCAATCGCATCCTCGATGCACTT
CTCAATCATCACTACTTAGAAAAGTATCAAGTAAGCACCAGTATGGGGGTTACTCAATGGAAAGATAAAGATACTGAAAG
TAGCCTATATCAGCGCGCCGATAATGCCTTATATGAAGCAAAAGCGGCAGGTAGACAATGCTACCAAATTTGTGCCGCTT
AG

Upstream 100 bases:

>100_bases
CCCTACAAAGATAATACACCACAGTAAAGGCACGATTTTTGCTTACTTAGACAAGGTAAGTCATATTGACGCTGTAACAA
AACACTGGGAGAAAAAACCA

Downstream 100 bases:

>100_bases
AAGCAGTCAGATGAATGAAGAATTGTAGACAGGGCTAACTGCCCACTCAAGCGTGTCTAAGACTCAGATTGAGTCCCAAA
GCTTGGTTGCTCGCTAAATA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MELGLATESFPIKYRQQTEIGMSTSLDIDLVNIIQQLHQHLDPRTVFACFGQIMGQHLPLYGVRLTYKQYQFHWGQTYGY
AFEQKLTFSDQQVTINYNLKAALVPSQTLMLNQLKDLVLQPLINAIQYQEMSQQAMYDALTKLGNRHYYQQSLKKEIARA
KRNQSSFSLIVLDLDNFKQLNDDFGHQLGDSALVEFADMLNATIRDTDQAFRIGGDEFTLLVQADVDEARVLCNRILDAL
LNHHYLEKYQVSTSMGVTQWKDKDTESSLYQRADNALYEAKAAGRQCYQICAA

Sequences:

>Translated_293_residues
MELGLATESFPIKYRQQTEIGMSTSLDIDLVNIIQQLHQHLDPRTVFACFGQIMGQHLPLYGVRLTYKQYQFHWGQTYGY
AFEQKLTFSDQQVTINYNLKAALVPSQTLMLNQLKDLVLQPLINAIQYQEMSQQAMYDALTKLGNRHYYQQSLKKEIARA
KRNQSSFSLIVLDLDNFKQLNDDFGHQLGDSALVEFADMLNATIRDTDQAFRIGGDEFTLLVQADVDEARVLCNRILDAL
LNHHYLEKYQVSTSMGVTQWKDKDTESSLYQRADNALYEAKAAGRQCYQICAA
>Mature_293_residues
MELGLATESFPIKYRQQTEIGMSTSLDIDLVNIIQQLHQHLDPRTVFACFGQIMGQHLPLYGVRLTYKQYQFHWGQTYGY
AFEQKLTFSDQQVTINYNLKAALVPSQTLMLNQLKDLVLQPLINAIQYQEMSQQAMYDALTKLGNRHYYQQSLKKEIARA
KRNQSSFSLIVLDLDNFKQLNDDFGHQLGDSALVEFADMLNATIRDTDQAFRIGGDEFTLLVQADVDEARVLCNRILDAL
LNHHYLEKYQVSTSMGVTQWKDKDTESSLYQRADNALYEAKAAGRQCYQICAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=197, Percent_Identity=30.9644670050761, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=33.7209302325581, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787262, Length=157, Percent_Identity=34.3949044585987, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786584, Length=195, Percent_Identity=28.7179487179487, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=34.8387096774194, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082007, Length=160, Percent_Identity=37.5, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081881, Length=164, Percent_Identity=33.5365853658537, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787816, Length=153, Percent_Identity=32.0261437908497, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788085, Length=168, Percent_Identity=31.547619047619, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787056, Length=156, Percent_Identity=32.6923076923077, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=29.1139240506329, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787541, Length=162, Percent_Identity=32.0987654320988, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081977, Length=154, Percent_Identity=31.1688311688312, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 33633; Mature: 33633

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELGLATESFPIKYRQQTEIGMSTSLDIDLVNIIQQLHQHLDPRTVFACFGQIMGQHLPL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCE
YGVRLTYKQYQFHWGQTYGYAFEQKLTFSDQQVTINYNLKAALVPSQTLMLNQLKDLVLQ
EEEEEEHHHHHEECCCCCCHHHHHEEEECCCEEEEEECEEEEECCCHHHHHHHHHHHHHH
PLINAIQYQEMSQQAMYDALTKLGNRHYYQQSLKKEIARAKRNQSSFSLIVLDLDNFKQL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHH
NDDFGHQLGDSALVEFADMLNATIRDTDQAFRIGGDEFTLLVQADVDEARVLCNRILDAL
HHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHEECCCEEEEEEECCCHHHHHHHHHHHHHH
LNHHYLEKYQVSTSMGVTQWKDKDTESSLYQRADNALYEAKAAGRQCYQICAA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELGLATESFPIKYRQQTEIGMSTSLDIDLVNIIQQLHQHLDPRTVFACFGQIMGQHLPL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCE
YGVRLTYKQYQFHWGQTYGYAFEQKLTFSDQQVTINYNLKAALVPSQTLMLNQLKDLVLQ
EEEEEEHHHHHEECCCCCCHHHHHEEEECCCEEEEEECEEEEECCCHHHHHHHHHHHHHH
PLINAIQYQEMSQQAMYDALTKLGNRHYYQQSLKKEIARAKRNQSSFSLIVLDLDNFKQL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHH
NDDFGHQLGDSALVEFADMLNATIRDTDQAFRIGGDEFTLLVQADVDEARVLCNRILDAL
HHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHEECCCEEEEEEECCCHHHHHHHHHHHHHH
LNHHYLEKYQVSTSMGVTQWKDKDTESSLYQRADNALYEAKAAGRQCYQICAA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]