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The map label for this gene is cysS [H]

Identifier: 157962505

GI number: 157962505

Start: 3271676

End: 3273055

Strand: Reverse

Name: cysS [H]

Synonym: Spea_2684

Alternate gene names: 157962505

Gene position: 3273055-3271676 (Counterclockwise)

Preceding gene: 157962508

Following gene: 157962503

Centisome position: 63.25

GC content: 45.58

Gene sequence:

>1380_bases
ATGTTGAAGCTTTACAATAGTCTGACCCGCCAAAAAGAGCAGTTTGTGCCACTACAACCAGGAAAGGTTGGCATGTATGT
GTGTGGGGTGACCATCTATGATTTATGTCATATTGGCCACGGACGTACATTTGTATCTTTTGACATGATTGTTAGATACC
TAAGATACAGCGGTTACGATGTTAATTTTCAGCGCAATATTACTGACGTCGATGACAAAATCATTAAGCGTGCAAATGAA
AACAAGGAAAGTTGTGATTCATTAACAGAGCGTTTGATCGCCGAGATGCACCGTGATTTTGATGCGCTGAATATGGCGCG
TCCAGACAATGAACCTCGTGCGACGCTGCACATGCCTGAAATCATCGAGATGGTTGAAAAACTTATCGAACGTGAACATG
CCTACGTGGCTTCTAATGGCGATGTGCTATTTAGCGTATCGTCATTCCCTGAGTATGGCCGTTTATCTGGCCAGAACCTT
GAGCAGCTGCAAGCGGGCGCACGCGTAGAAGTTGAAGATGCAAAGCGCGATCCGATGGACTTTGTGCTTTGGAAGATGTC
AAAGCCTGGCGAGCCGACATGGGAATCGCCATGGGGACCGGGTCGCCCTGGTTGGCACATCGAATGTTCTGCAATGAACA
GCAAGCATTTAGGTAATCACTTCGATATTCATGGCGGTGGCTCTGATCTACAGTTCCCACATCATGAAAATGAAATCGCT
CAGTCATGCTGCGCTCACGATACGCCGTATGTTAACTACTGGATGCATACAGGCATGGTGATGGTTGATAAAGAAAAGAT
GTCAAAGTCTTTGAATAACTTCTTCACTATCCGGGACGTGTTAGGTCACTATGATGCGACGACTGTGCGTTACTTCTTAT
TATCTGGTCATTATCGTAGTCAGCTTAATTACTCAGAAGATAATCTTAAGCAGGCTAAATCTGGACTTGAACGTATTTAC
ACAGCGCTTAAAGATCTAGATTTAACCGTTGAAGCTGCGCCAGCTGAAGAGTTTGTGGCTAAGTTTAAGTCAGCGATGGA
TGACGACTTTAATACGCCTGAAGCATACTCAGTGTTGTTTGATATGGTGCGTGAGATCAACCGCCTGAAAGCAACCGATA
TGGCCAAAGCCTCAGCCTTAGGTGTTGCCCTAAAACAACTTGCAGATGTGTTAGGCATTTTAGGTCAAGACGTCGATACC
TTCTTCAAAGGTGAAGGTAATGACGACGAAGTCGCAGAAATTGAAGCGCTAATCGTTGAGCGTAACCGCGCCCGAGCCGA
AAAAGACTGGCCTGCCGCTGATGTTGCACGTGATGGCTTAAATGCTTTAGGTGTGATTTTAGAAGATGGTCCAGAAGGCA
CCACTTGGCGTAAGAAGTAA

Upstream 100 bases:

>100_bases
TTTTGCGAACTTTGAACGCGAAAACAGCTTGGAACAGCGACTTTTGCAGTGGTAAACTGGAAAACACATTTTTACAGATA
GCCGTTGAAGAGAATAATCA

Downstream 100 bases:

>100_bases
TTCTTAACGAGTGATTGTTCGGATGTAAAACATAAAAAAGCCTGCTAATTGCAGGCTTTTCTTTTTTGAGTAACTAGGTC
TGGAACACTTATGCTACACC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLKLYNSLTRQKEQFVPLQPGKVGMYVCGVTIYDLCHIGHGRTFVSFDMIVRYLRYSGYDVNFQRNITDVDDKIIKRANE
NKESCDSLTERLIAEMHRDFDALNMARPDNEPRATLHMPEIIEMVEKLIEREHAYVASNGDVLFSVSSFPEYGRLSGQNL
EQLQAGARVEVEDAKRDPMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGNHFDIHGGGSDLQFPHHENEIA
QSCCAHDTPYVNYWMHTGMVMVDKEKMSKSLNNFFTIRDVLGHYDATTVRYFLLSGHYRSQLNYSEDNLKQAKSGLERIY
TALKDLDLTVEAAPAEEFVAKFKSAMDDDFNTPEAYSVLFDMVREINRLKATDMAKASALGVALKQLADVLGILGQDVDT
FFKGEGNDDEVAEIEALIVERNRARAEKDWPAADVARDGLNALGVILEDGPEGTTWRKK

Sequences:

>Translated_459_residues
MLKLYNSLTRQKEQFVPLQPGKVGMYVCGVTIYDLCHIGHGRTFVSFDMIVRYLRYSGYDVNFQRNITDVDDKIIKRANE
NKESCDSLTERLIAEMHRDFDALNMARPDNEPRATLHMPEIIEMVEKLIEREHAYVASNGDVLFSVSSFPEYGRLSGQNL
EQLQAGARVEVEDAKRDPMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGNHFDIHGGGSDLQFPHHENEIA
QSCCAHDTPYVNYWMHTGMVMVDKEKMSKSLNNFFTIRDVLGHYDATTVRYFLLSGHYRSQLNYSEDNLKQAKSGLERIY
TALKDLDLTVEAAPAEEFVAKFKSAMDDDFNTPEAYSVLFDMVREINRLKATDMAKASALGVALKQLADVLGILGQDVDT
FFKGEGNDDEVAEIEALIVERNRARAEKDWPAADVARDGLNALGVILEDGPEGTTWRKK
>Mature_459_residues
MLKLYNSLTRQKEQFVPLQPGKVGMYVCGVTIYDLCHIGHGRTFVSFDMIVRYLRYSGYDVNFQRNITDVDDKIIKRANE
NKESCDSLTERLIAEMHRDFDALNMARPDNEPRATLHMPEIIEMVEKLIEREHAYVASNGDVLFSVSSFPEYGRLSGQNL
EQLQAGARVEVEDAKRDPMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGNHFDIHGGGSDLQFPHHENEIA
QSCCAHDTPYVNYWMHTGMVMVDKEKMSKSLNNFFTIRDVLGHYDATTVRYFLLSGHYRSQLNYSEDNLKQAKSGLERIY
TALKDLDLTVEAAPAEEFVAKFKSAMDDDFNTPEAYSVLFDMVREINRLKATDMAKASALGVALKQLADVLGILGQDVDT
FFKGEGNDDEVAEIEALIVERNRARAEKDWPAADVARDGLNALGVILEDGPEGTTWRKK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=505, Percent_Identity=34.8514851485148, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI10835051, Length=250, Percent_Identity=41.6, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI21269877, Length=250, Percent_Identity=41.6, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI303304987, Length=250, Percent_Identity=41.6, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI62240992, Length=250, Percent_Identity=41.6, Blast_Score=194, Evalue=2e-49,
Organism=Escherichia coli, GI1786737, Length=461, Percent_Identity=70.0650759219089, Blast_Score=674, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509797, Length=246, Percent_Identity=40.650406504065, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17509795, Length=246, Percent_Identity=40.650406504065, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324082, Length=330, Percent_Identity=35.1515151515151, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19922218, Length=501, Percent_Identity=35.5289421157685, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI19922364, Length=249, Percent_Identity=41.7670682730924, Blast_Score=185, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 52034; Mature: 52034

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLYNSLTRQKEQFVPLQPGKVGMYVCGVTIYDLCHIGHGRTFVSFDMIVRYLRYSGYD
CCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
VNFQRNITDVDDKIIKRANENKESCDSLTERLIAEMHRDFDALNMARPDNEPRATLHMPE
CEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCEEECHHH
IIEMVEKLIEREHAYVASNGDVLFSVSSFPEYGRLSGQNLEQLQAGARVEVEDAKRDPMD
HHHHHHHHHHHHHCEEECCCCEEEEECCCCCCCCCCCCCHHHHHCCCCEEECCCCCCCHH
FVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGNHFDIHGGGSDLQFPHHENEIA
HEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHH
QSCCAHDTPYVNYWMHTGMVMVDKEKMSKSLNNFFTIRDVLGHYDATTVRYFLLSGHYRS
HHHHCCCCCCCHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
QLNYSEDNLKQAKSGLERIYTALKDLDLTVEAAPAEEFVAKFKSAMDDDFNTPEAYSVLF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHH
DMVREINRLKATDMAKASALGVALKQLADVLGILGQDVDTFFKGEGNDDEVAEIEALIVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHH
RNRARAEKDWPAADVARDGLNALGVILEDGPEGTTWRKK
HHHHCCCCCCCHHHHHHCCHHHEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLKLYNSLTRQKEQFVPLQPGKVGMYVCGVTIYDLCHIGHGRTFVSFDMIVRYLRYSGYD
CCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
VNFQRNITDVDDKIIKRANENKESCDSLTERLIAEMHRDFDALNMARPDNEPRATLHMPE
CEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCEEECHHH
IIEMVEKLIEREHAYVASNGDVLFSVSSFPEYGRLSGQNLEQLQAGARVEVEDAKRDPMD
HHHHHHHHHHHHHCEEECCCCEEEEECCCCCCCCCCCCCHHHHHCCCCEEECCCCCCCHH
FVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGNHFDIHGGGSDLQFPHHENEIA
HEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHH
QSCCAHDTPYVNYWMHTGMVMVDKEKMSKSLNNFFTIRDVLGHYDATTVRYFLLSGHYRS
HHHHCCCCCCCHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
QLNYSEDNLKQAKSGLERIYTALKDLDLTVEAAPAEEFVAKFKSAMDDDFNTPEAYSVLF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHH
DMVREINRLKATDMAKASALGVALKQLADVLGILGQDVDTFFKGEGNDDEVAEIEALIVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHH
RNRARAEKDWPAADVARDGLNALGVILEDGPEGTTWRKK
HHHHCCCCCCCHHHHHHCCHHHEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA