Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 157962242

GI number: 157962242

Start: 2958596

End: 2960590

Strand: Direct

Name: recD [H]

Synonym: Spea_2421

Alternate gene names: 157962242

Gene position: 2958596-2960590 (Clockwise)

Preceding gene: 157962241

Following gene: 157962243

Centisome position: 57.18

GC content: 48.02

Gene sequence:

>1995_bases
ATGATCACCACCACTAAGCCGATTAACGATTTACTCAAAGAGTGGCAAGAGCAGCGGCTTCTCACCTCGCTCGACCGGCA
CTTTGCCCTGCAATTAGCCCAGCTTCATCAAGAAACTGCGCCGTTATTCACGCTTATTTGTTCCTTAGTGAGTCAGTATC
TCTCAAGCCAGCATACCTGTCTGCCGCTAAAACAGATTGATACCAGCAATCCATTTAAAGAGCAGATCAGCCAATGCCAA
ATCAATATCAACATTGATGAGCTTGAACAAACGTTGTTGCAGTTTGACGCCATTGGCACTGCCGATGACGCCGAGCTTAA
ACCTTTGATAATCGATAAAGGTAACCTGTATCTTCAGCGTTATTTTAGCTACGAGACGCAGGTTGCCGAACATCTGAATC
GACTCTCTTTTGCGCCAGTTGACTCTAGTCTTAATGATGACACTGAACTGGCGAGCGCCAGTGAACTATTAAATCAGTTA
TTTCCAGCCAATGAGCAGCAATATGACTGGCAAAAGATCGCCACCGCCACTGCTATGACAAAAAAGCTAGCCGTTATTAC
AGGCGGCCCTGGTACGGGTAAAACCACAACCGTTACTAAGCTGCTGTATTTATTATGCTCAAGGCAGGAGATGACGATTA
GGCTAGTCGCCCCAACGGGTAAGGCTGCGGCGCGCCTTAGTGAGTCGATTAAAGCGTCAAAGCTTAGACTTGCCAGTGAG
ATGAGCCAAATTGGCACTGCAGATCTCGAAAAAAACATCGCTAAAATCCCAGAAGAAGCGGCCACCCTACACCGCTTACT
TGGGGTGATCCCAAATTCACACCAATTTAGGCATCATAAAGACAACCCACTCAGGCTGGATCTGTTAGTGATAGATGAAG
CCTCCATGGTTGATTTACCTATGATGCACAAGGTGCTATCGGCTCTGCCTGAGCATGCTAAATTAATTCTACTTGGCGAC
CAAGATCAGCTCGCCTCAGTTGAAGCGGGCGCGGTGCTTGCCGATATCTGTGCTGGTTTAAAACAAGTTAATAAGAAAAC
AAAGCAGAGTCGCTGGCAGATGCATTACTCACCAGCGCAAGTTGAGCTACTGAGCCAGTTAACCAGCACCTCCTTAGCGG
AGTTTGCCAGCGCAAATCCAAAAATCGGTGATAGCTTATGCATGCTGATGCACAGCCACCGCTTTCAGGGGGATGCCGGT
ATTGGTCAATTGGCAACGGCGGTCAATCACTCTAACTTACCTCGTATCGCCGAGGTTTGGCAGACAGGCTATCAAGAATT
ATGCTGGATAGAACATGCTATCGCTAATACTGCCCACGGCAGCAGTTCGCAAGTAAATAGCTCATCAGCTAATAAAGGGC
TTGAAGCGCTACTTGTTCAGACCATTGAGCAATATGGCGTGTACCTAGCGGCCATCTCACAAGGGGACGTCGATGCAGAC
AAGATCATCGACAGCTTTAATCAATACCGTATTTTATGTGCCATGCGCGCCGGAGAATATGGCGTCGAGGGAATAAACCA
GAGTGTCACTACAGCACTAGCCGCTAAGGGACTCATCCATCCGGAGCAAGAGTTTTATGCTGGCCGCCCTATCATCATTC
AGAGCAATGATTACAACCTAGGCTTATTTAACGGTGATATCGGCTTGATTTTACCCGATAGCAGTAGCCAAACAGGTCGT
TTAATGGCGCACTTTATTCAGGCCGACGGCAGCTTACTTAAGGTGCTACCAGCGCGATTACCGAGCCATGAGACCTGTTA
TGCCATGACTGTACATAAGAGCCAAGGTAGTGAGTTTAACCATGTATCCTTGGTGCTACCGATAAAACCAAGTATCGCAC
AGCAACAGCTCTTAACTAAAGAGTTAGTCTATACCGCCATCACTCGCGCAAAGCATCACTTTACCTGCCTTGGCAGCCAG
AGAGTGTTTGAGCAAGCCAGTCGCTGTCTAACCCAGCGAGCCTCGGGCTTGGCGCAACGTTTATGGCGCGATTAA

Upstream 100 bases:

>100_bases
AGCCGCCTAAGTTACTAATTGAGAAGCTCGATGCCTTATTCGGGAACCAGATGACAGCACAAAGTATTGAACAGTCAAAT
AACGCTCAAGTGGAGGTCAA

Downstream 100 bases:

>100_bases
CTTTTTGAGGTTTGTCTAGCTAAGCTTTCACTTTTAGTGGCTTAACAGTTGAGCAGTGTTGTTAAGTTCAAGTTGTTAAG
CTCTAGTTGCTAAGTTCAAG

Product: exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MITTTKPINDLLKEWQEQRLLTSLDRHFALQLAQLHQETAPLFTLICSLVSQYLSSQHTCLPLKQIDTSNPFKEQISQCQ
ININIDELEQTLLQFDAIGTADDAELKPLIIDKGNLYLQRYFSYETQVAEHLNRLSFAPVDSSLNDDTELASASELLNQL
FPANEQQYDWQKIATATAMTKKLAVITGGPGTGKTTTVTKLLYLLCSRQEMTIRLVAPTGKAAARLSESIKASKLRLASE
MSQIGTADLEKNIAKIPEEAATLHRLLGVIPNSHQFRHHKDNPLRLDLLVIDEASMVDLPMMHKVLSALPEHAKLILLGD
QDQLASVEAGAVLADICAGLKQVNKKTKQSRWQMHYSPAQVELLSQLTSTSLAEFASANPKIGDSLCMLMHSHRFQGDAG
IGQLATAVNHSNLPRIAEVWQTGYQELCWIEHAIANTAHGSSSQVNSSSANKGLEALLVQTIEQYGVYLAAISQGDVDAD
KIIDSFNQYRILCAMRAGEYGVEGINQSVTTALAAKGLIHPEQEFYAGRPIIIQSNDYNLGLFNGDIGLILPDSSSQTGR
LMAHFIQADGSLLKVLPARLPSHETCYAMTVHKSQGSEFNHVSLVLPIKPSIAQQQLLTKELVYTAITRAKHHFTCLGSQ
RVFEQASRCLTQRASGLAQRLWRD

Sequences:

>Translated_664_residues
MITTTKPINDLLKEWQEQRLLTSLDRHFALQLAQLHQETAPLFTLICSLVSQYLSSQHTCLPLKQIDTSNPFKEQISQCQ
ININIDELEQTLLQFDAIGTADDAELKPLIIDKGNLYLQRYFSYETQVAEHLNRLSFAPVDSSLNDDTELASASELLNQL
FPANEQQYDWQKIATATAMTKKLAVITGGPGTGKTTTVTKLLYLLCSRQEMTIRLVAPTGKAAARLSESIKASKLRLASE
MSQIGTADLEKNIAKIPEEAATLHRLLGVIPNSHQFRHHKDNPLRLDLLVIDEASMVDLPMMHKVLSALPEHAKLILLGD
QDQLASVEAGAVLADICAGLKQVNKKTKQSRWQMHYSPAQVELLSQLTSTSLAEFASANPKIGDSLCMLMHSHRFQGDAG
IGQLATAVNHSNLPRIAEVWQTGYQELCWIEHAIANTAHGSSSQVNSSSANKGLEALLVQTIEQYGVYLAAISQGDVDAD
KIIDSFNQYRILCAMRAGEYGVEGINQSVTTALAAKGLIHPEQEFYAGRPIIIQSNDYNLGLFNGDIGLILPDSSSQTGR
LMAHFIQADGSLLKVLPARLPSHETCYAMTVHKSQGSEFNHVSLVLPIKPSIAQQQLLTKELVYTAITRAKHHFTCLGSQ
RVFEQASRCLTQRASGLAQRLWRD
>Mature_664_residues
MITTTKPINDLLKEWQEQRLLTSLDRHFALQLAQLHQETAPLFTLICSLVSQYLSSQHTCLPLKQIDTSNPFKEQISQCQ
ININIDELEQTLLQFDAIGTADDAELKPLIIDKGNLYLQRYFSYETQVAEHLNRLSFAPVDSSLNDDTELASASELLNQL
FPANEQQYDWQKIATATAMTKKLAVITGGPGTGKTTTVTKLLYLLCSRQEMTIRLVAPTGKAAARLSESIKASKLRLASE
MSQIGTADLEKNIAKIPEEAATLHRLLGVIPNSHQFRHHKDNPLRLDLLVIDEASMVDLPMMHKVLSALPEHAKLILLGD
QDQLASVEAGAVLADICAGLKQVNKKTKQSRWQMHYSPAQVELLSQLTSTSLAEFASANPKIGDSLCMLMHSHRFQGDAG
IGQLATAVNHSNLPRIAEVWQTGYQELCWIEHAIANTAHGSSSQVNSSSANKGLEALLVQTIEQYGVYLAAISQGDVDAD
KIIDSFNQYRILCAMRAGEYGVEGINQSVTTALAAKGLIHPEQEFYAGRPIIIQSNDYNLGLFNGDIGLILPDSSSQTGR
LMAHFIQADGSLLKVLPARLPSHETCYAMTVHKSQGSEFNHVSLVLPIKPSIAQQQLLTKELVYTAITRAKHHFTCLGSQ
RVFEQASRCLTQRASGLAQRLWRD

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=655, Percent_Identity=40.4580152671756, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 73292; Mature: 73292

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTTKPINDLLKEWQEQRLLTSLDRHFALQLAQLHQETAPLFTLICSLVSQYLSSQHTC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LPLKQIDTSNPFKEQISQCQININIDELEQTLLQFDAIGTADDAELKPLIIDKGNLYLQR
CCHHHCCCCCHHHHHHHHEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEHH
YFSYETQVAEHLNRLSFAPVDSSLNDDTELASASELLNQLFPANEQQYDWQKIATATAMT
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KKLAVITGGPGTGKTTTVTKLLYLLCSRQEMTIRLVAPTGKAAARLSESIKASKLRLASE
HEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
MSQIGTADLEKNIAKIPEEAATLHRLLGVIPNSHQFRHHKDNPLRLDLLVIDEASMVDLP
HHHHCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHH
MMHKVLSALPEHAKLILLGDQDQLASVEAGAVLADICAGLKQVNKKTKQSRWQMHYSPAQ
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHH
VELLSQLTSTSLAEFASANPKIGDSLCMLMHSHRFQGDAGIGQLATAVNHSNLPRIAEVW
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHH
QTGYQELCWIEHAIANTAHGSSSQVNSSSANKGLEALLVQTIEQYGVYLAAISQGDVDAD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
KIIDSFNQYRILCAMRAGEYGVEGINQSVTTALAAKGLIHPEQEFYAGRPIIIQSNDYNL
HHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCEEEECCCCEE
GLFNGDIGLILPDSSSQTGRLMAHFIQADGSLLKVLPARLPSHETCYAMTVHKSQGSEFN
EEEECCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
HVSLVLPIKPSIAQQQLLTKELVYTAITRAKHHFTCLGSQRVFEQASRCLTQRASGLAQR
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHH
LWRD
HCCC
>Mature Secondary Structure
MITTTKPINDLLKEWQEQRLLTSLDRHFALQLAQLHQETAPLFTLICSLVSQYLSSQHTC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LPLKQIDTSNPFKEQISQCQININIDELEQTLLQFDAIGTADDAELKPLIIDKGNLYLQR
CCHHHCCCCCHHHHHHHHEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEHH
YFSYETQVAEHLNRLSFAPVDSSLNDDTELASASELLNQLFPANEQQYDWQKIATATAMT
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KKLAVITGGPGTGKTTTVTKLLYLLCSRQEMTIRLVAPTGKAAARLSESIKASKLRLASE
HEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
MSQIGTADLEKNIAKIPEEAATLHRLLGVIPNSHQFRHHKDNPLRLDLLVIDEASMVDLP
HHHHCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHH
MMHKVLSALPEHAKLILLGDQDQLASVEAGAVLADICAGLKQVNKKTKQSRWQMHYSPAQ
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHH
VELLSQLTSTSLAEFASANPKIGDSLCMLMHSHRFQGDAGIGQLATAVNHSNLPRIAEVW
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHH
QTGYQELCWIEHAIANTAHGSSSQVNSSSANKGLEALLVQTIEQYGVYLAAISQGDVDAD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
KIIDSFNQYRILCAMRAGEYGVEGINQSVTTALAAKGLIHPEQEFYAGRPIIIQSNDYNL
HHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCEEEECCCCEE
GLFNGDIGLILPDSSSQTGRLMAHFIQADGSLLKVLPARLPSHETCYAMTVHKSQGSEFN
EEEECCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
HVSLVLPIKPSIAQQQLLTKELVYTAITRAKHHFTCLGSQRVFEQASRCLTQRASGLAQR
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHH
LWRD
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]