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The map label for this gene is era [H]

Identifier: 157960866

GI number: 157960866

Start: 1260785

End: 1261777

Strand: Direct

Name: era [H]

Synonym: Spea_1038

Alternate gene names: 157960866

Gene position: 1260785-1261777 (Clockwise)

Preceding gene: 157960865

Following gene: 157960867

Centisome position: 24.36

GC content: 45.52

Gene sequence:

>993_bases
ATGAGTGACAACAAAGATTTACCTGAAAGCCAAGAGCCAAGTTTAGACGAACTACTGGCTAATATGAACAATCCGTCGTC
AGCGGTTAAGTACGCGGTGACCTATTGCGGCATGGTGGCGATCGTTGGTCGCCCAAACGTGGGTAAGTCAACGCTTCTTA
ATAAGCTCTTAGGTCAGAAGATTAGTATTACCTCTAAGAAGCCGCAAACTACCCGTCATCGCATCATGGGTATTCATACT
GATGGTCCACGTCAGGTAGTGTTTATCGACACTCCTGGTCTTCATATGGAAGAGAAGCGTGCGATTAACCGTTTGATGAA
CCGCGCTGCGGCAAGTTCGTTAGCAGAAGTGGCATTAGTGGTATTTGTTGTTGACGGTATGAACTGGACGCCAGATGATG
AGATGGTTCTGCGTAAACTGCAGAGTCGTGATGATGGTCGTAAGACGATTCTAGCAATCAACAAAGTCGATAACATTAAA
GACAAAGAAGCGCTGTTCCCACACCTTGAAGAGTTATCGAAGAAGTTTCCTTTCGATGAGATTTTACCGATTTCAGCAAC
TCAAGGCACCAACGTTCAACGCATCCTAGATATGTCAGTCGCCTCTGTACCTGAGTCGCCACATTACTTCCCTGAAGATT
ACGTGACAGACCGTTCGCAGAAGTTTATGGCTTCTGAAATTGTTCGTGAAAAGCTGATGCGTTTCTTGGGTGACGAATTG
CCATACGATTGTACGGTAGAGATCGAACAGTTTAAGATGATGGAAAACGGCGTTTACCAGATCAACGCTTTGGTGCTTGT
TGAGCGCGAAACTCAAAAGCGTATGGTGATTGGTAATAAAGGCGAGCGCATCAAAAAAATCAGTTCTGCTGCACGCGTCG
ATATGGAAGTCTTGTTTGATAACAAGGTTTTCTTGGAGATGTGGGTTAAAGTTAAGTCAGGCTGGGCTGATGACGAACGC
GCACTGCGAAGCTTAGGTTATGGTGACGATTAG

Upstream 100 bases:

>100_bases
GTATTGTTGAAGACTTGAGCCAAGCCGTTGTCGGAGTAGCCAGTTCGCGCAGAAAAGCGGAACAGAGTGCTGCGGCTCAA
GTGTTGGAGTTAATTAAGAA

Downstream 100 bases:

>100_bases
TCGCCACTAGCTTGATAGCGAAACATGCCTCTTTTTAGTGATAAGAAGGGGCATTTTTATAGCCAGCATATTAATGAATC
ATCCCGTTTTCTTTTTACAA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSDNKDLPESQEPSLDELLANMNNPSSAVKYAVTYCGMVAIVGRPNVGKSTLLNKLLGQKISITSKKPQTTRHRIMGIHT
DGPRQVVFIDTPGLHMEEKRAINRLMNRAAASSLAEVALVVFVVDGMNWTPDDEMVLRKLQSRDDGRKTILAINKVDNIK
DKEALFPHLEELSKKFPFDEILPISATQGTNVQRILDMSVASVPESPHYFPEDYVTDRSQKFMASEIVREKLMRFLGDEL
PYDCTVEIEQFKMMENGVYQINALVLVERETQKRMVIGNKGERIKKISSAARVDMEVLFDNKVFLEMWVKVKSGWADDER
ALRSLGYGDD

Sequences:

>Translated_330_residues
MSDNKDLPESQEPSLDELLANMNNPSSAVKYAVTYCGMVAIVGRPNVGKSTLLNKLLGQKISITSKKPQTTRHRIMGIHT
DGPRQVVFIDTPGLHMEEKRAINRLMNRAAASSLAEVALVVFVVDGMNWTPDDEMVLRKLQSRDDGRKTILAINKVDNIK
DKEALFPHLEELSKKFPFDEILPISATQGTNVQRILDMSVASVPESPHYFPEDYVTDRSQKFMASEIVREKLMRFLGDEL
PYDCTVEIEQFKMMENGVYQINALVLVERETQKRMVIGNKGERIKKISSAARVDMEVLFDNKVFLEMWVKVKSGWADDER
ALRSLGYGDD
>Mature_329_residues
SDNKDLPESQEPSLDELLANMNNPSSAVKYAVTYCGMVAIVGRPNVGKSTLLNKLLGQKISITSKKPQTTRHRIMGIHTD
GPRQVVFIDTPGLHMEEKRAINRLMNRAAASSLAEVALVVFVVDGMNWTPDDEMVLRKLQSRDDGRKTILAINKVDNIKD
KEALFPHLEELSKKFPFDEILPISATQGTNVQRILDMSVASVPESPHYFPEDYVTDRSQKFMASEIVREKLMRFLGDELP
YDCTVEIEQFKMMENGVYQINALVLVERETQKRMVIGNKGERIKKISSAARVDMEVLFDNKVFLEMWVKVKSGWADDERA
LRSLGYGDD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=321, Percent_Identity=25.8566978193146, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1788919, Length=297, Percent_Identity=67.003367003367, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI87082120, Length=161, Percent_Identity=32.9192546583851, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646434, Length=305, Percent_Identity=26.5573770491803, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37369; Mature: 37237

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNKDLPESQEPSLDELLANMNNPSSAVKYAVTYCGMVAIVGRPNVGKSTLLNKLLGQK
CCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCE
ISITSKKPQTTRHRIMGIHTDGPRQVVFIDTPGLHMEEKRAINRLMNRAAASSLAEVALV
EEECCCCCCCCHHHEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VFVVDGMNWTPDDEMVLRKLQSRDDGRKTILAINKVDNIKDKEALFPHLEELSKKFPFDE
HHEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHH
ILPISATQGTNVQRILDMSVASVPESPHYFPEDYVTDRSQKFMASEIVREKLMRFLGDEL
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
PYDCTVEIEQFKMMENGVYQINALVLVERETQKRMVIGNKGERIKKISSAARVDMEVLFD
CCCEEEHHHHHHHHHCCCEEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCEEEEC
NKVFLEMWVKVKSGWADDERALRSLGYGDD
CHHHHHHHHHHHCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
SDNKDLPESQEPSLDELLANMNNPSSAVKYAVTYCGMVAIVGRPNVGKSTLLNKLLGQK
CCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCE
ISITSKKPQTTRHRIMGIHTDGPRQVVFIDTPGLHMEEKRAINRLMNRAAASSLAEVALV
EEECCCCCCCCHHHEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VFVVDGMNWTPDDEMVLRKLQSRDDGRKTILAINKVDNIKDKEALFPHLEELSKKFPFDE
HHEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHH
ILPISATQGTNVQRILDMSVASVPESPHYFPEDYVTDRSQKFMASEIVREKLMRFLGDEL
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
PYDCTVEIEQFKMMENGVYQINALVLVERETQKRMVIGNKGERIKKISSAARVDMEVLFD
CCCEEEHHHHHHHHHCCCEEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCEEEEC
NKVFLEMWVKVKSGWADDERALRSLGYGDD
CHHHHHHHHHHHCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]