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The map label for this gene is surA [H]

Identifier: 157960692

GI number: 157960692

Start: 1061938

End: 1063242

Strand: Reverse

Name: surA [H]

Synonym: Spea_0864

Alternate gene names: 157960692

Gene position: 1063242-1061938 (Counterclockwise)

Preceding gene: 157960693

Following gene: 157960691

Centisome position: 20.55

GC content: 44.52

Gene sequence:

>1305_bases
ATGAAACGCTGTAACCAATTGATTTTTGCACTTTTAACATTGGCGATGAGCCAGACGATTCAAGCTGCGCCAGAACCACT
TGACCGAGTCACAGTGCAGATAAATGAAGGGATCATTCTAGAGAGTGAAGTTGCTGGCATGGTTAAGACCATTAAGGCTA
ATGCTGCCAATGCTGGTCAGAAGTTACCATCTGATACCGCACTGCGCACTCAGGTTATTGAGCGTCTTATTTTGACCCGT
TTGCAGTTACAGATGGCAGATAGAATTGGTTTGCACATTGGTGACTTACAGTTAGATCAAACCATCGAAAATATTGCTAA
AGAGCAAAAAATTACGGTCGCGCAAATGAAAGCGCAAATTGAGAGTGAAGGTACAACATTCGCTCAATACCGTGAACAAC
TACGTGAAGAGATCACCCTTGGTGAGATCCAGCGCATCCAGGTTCAACGTCGTATTCAAGTATCACCACAAGAGATCAAT
AACCTAGTTAAGCTCATCAACGAGCAAGGACTGAAGGAGGTTGAGTTCCAGATTGGTCATATCCTGATTGACGTACCAAG
CGACGCCAATAGCCAACAGCTTGAAGCCGCGAGCAAAAGATCCGCGACAGTCATGAAACGCCTCAAAGATGGCGATGACT
TTAGAAGTATCGCAATTGCAGCATCTTCAGGTCCTAAGGCGCTTGAAGGCGGGATCTGGGACTACATGAATATCAACGAA
ATGCCGACTTTATTTGCTGAAGTTGTCGGAGATGCTAAAACCGGTGATATCATAGGACCAATTAAGAGTGCATCTGGTTT
CCATATCATCAAAGTTATGGACGCTCGCGGCCTACAGACTAAAGAAGTACAAGAGGTTAAATCTCGCCATATTTTACTTA
AGCCATCGCCGATTCTTTCAGAAGAACGTGCTAAGAGCATGATGGATAGATTCCTCGCTCAAGTTAAATCTGGCGAAGCC
AAGTTTGAAGACTTAGCCCGTCAATACTCTGAAGATCCTGGTTCTGCGGCTAAAGGCGGAGAATTAGGCTGGGCAGACCC
GAACATCTATGTACCCGCTTTTTCGCAAGAGCTGAATAGCCTAGAAGTTGGCGCGTACAGCGAGCCATTCCGTTCGACTC
ATGGCTGGCATATTGTTCAATTAGAAGAAAAACGTACAACCGACGCGACCGATAAATTTAATACGAATCGAGCTCATCAG
CTGATCTATCGTCGTAAATTTAATGAAGAGTTACAAAACTGGCTAGATGAAATGCGCGCTGAAGCATTTATCGATATATT
TGAGCCAGAAACGAATCGAGGTTAA

Upstream 100 bases:

>100_bases
ACCTAGCTAACGACATGCAGTCAAAGCAGGACTAAAGAATCATTAACCCGGTATGTAAATACCGTAAATGACACTCAATA
AATGCCAAGGATTTTAGTGG

Downstream 100 bases:

>100_bases
TACTATTGTCGACTAAACGCATAGCCATCACGCCGGGTGAACCGGCGGGTGTTGGCCCAGATTTAGTGATACAACTAGCT
CAGCAGGCTTGGCCTGCTGA

Product: SurA domain-containing protein

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKRCNQLIFALLTLAMSQTIQAAPEPLDRVTVQINEGIILESEVAGMVKTIKANAANAGQKLPSDTALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQTIENIAKEQKITVAQMKAQIESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEIN
NLVKLINEQGLKEVEFQIGHILIDVPSDANSQQLEAASKRSATVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
MPTLFAEVVGDAKTGDIIGPIKSASGFHIIKVMDARGLQTKEVQEVKSRHILLKPSPILSEERAKSMMDRFLAQVKSGEA
KFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFSQELNSLEVGAYSEPFRSTHGWHIVQLEEKRTTDATDKFNTNRAHQ
LIYRRKFNEELQNWLDEMRAEAFIDIFEPETNRG

Sequences:

>Translated_434_residues
MKRCNQLIFALLTLAMSQTIQAAPEPLDRVTVQINEGIILESEVAGMVKTIKANAANAGQKLPSDTALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQTIENIAKEQKITVAQMKAQIESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEIN
NLVKLINEQGLKEVEFQIGHILIDVPSDANSQQLEAASKRSATVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
MPTLFAEVVGDAKTGDIIGPIKSASGFHIIKVMDARGLQTKEVQEVKSRHILLKPSPILSEERAKSMMDRFLAQVKSGEA
KFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFSQELNSLEVGAYSEPFRSTHGWHIVQLEEKRTTDATDKFNTNRAHQ
LIYRRKFNEELQNWLDEMRAEAFIDIFEPETNRG
>Mature_434_residues
MKRCNQLIFALLTLAMSQTIQAAPEPLDRVTVQINEGIILESEVAGMVKTIKANAANAGQKLPSDTALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQTIENIAKEQKITVAQMKAQIESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEIN
NLVKLINEQGLKEVEFQIGHILIDVPSDANSQQLEAASKRSATVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
MPTLFAEVVGDAKTGDIIGPIKSASGFHIIKVMDARGLQTKEVQEVKSRHILLKPSPILSEERAKSMMDRFLAQVKSGEA
KFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFSQELNSLEVGAYSEPFRSTHGWHIVQLEEKRTTDATDKFNTNRAHQ
LIYRRKFNEELQNWLDEMRAEAFIDIFEPETNRG

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=419, Percent_Identity=41.7661097852029, Blast_Score=354, Evalue=8e-99,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48664; Mature: 48664

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRCNQLIFALLTLAMSQTIQAAPEPLDRVTVQINEGIILESEVAGMVKTIKANAANAGQ
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCEEEHHHHHHHHHHHHHCCCCCCC
KLPSDTALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQTIENIAKEQKITVAQMKAQI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEINNLVKLINEQGLKEVEFQIGH
HCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHEECE
ILIDVPSDANSQQLEAASKRSATVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCH
MPTLFAEVVGDAKTGDIIGPIKSASGFHIIKVMDARGLQTKEVQEVKSRHILLKPSPILS
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCEEEECCCCCCC
EERAKSMMDRFLAQVKSGEAKFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFSQELNS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCHHHHCCC
LEVGAYSEPFRSTHGWHIVQLEEKRTTDATDKFNTNRAHQLIYRRKFNEELQNWLDEMRA
EECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EAFIDIFEPETNRG
HHHHEEECCCCCCC
>Mature Secondary Structure
MKRCNQLIFALLTLAMSQTIQAAPEPLDRVTVQINEGIILESEVAGMVKTIKANAANAGQ
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCEEEHHHHHHHHHHHHHCCCCCCC
KLPSDTALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQTIENIAKEQKITVAQMKAQI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEINNLVKLINEQGLKEVEFQIGH
HCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHEECE
ILIDVPSDANSQQLEAASKRSATVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCH
MPTLFAEVVGDAKTGDIIGPIKSASGFHIIKVMDARGLQTKEVQEVKSRHILLKPSPILS
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCEEEECCCCCCC
EERAKSMMDRFLAQVKSGEAKFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFSQELNS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCHHHHCCC
LEVGAYSEPFRSTHGWHIVQLEEKRTTDATDKFNTNRAHQLIYRRKFNEELQNWLDEMRA
EECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EAFIDIFEPETNRG
HHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]