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The map label for this gene is siaT [H]

Identifier: 157372935

GI number: 157372935

Start: 5198056

End: 5199333

Strand: Reverse

Name: siaT [H]

Synonym: Spro_4703

Alternate gene names: 157372935

Gene position: 5199333-5198056 (Counterclockwise)

Preceding gene: 157372936

Following gene: 157372934

Centisome position: 95.42

GC content: 54.15

Gene sequence:

>1278_bases
ATGACGGTAGCGATCTCCTGCATTATTTTACTGCTGGGTTTTATCAGCAAATTACCGATATTTATCAGTGTGATCCTGGC
GGTATTGAGTTGGTTTTTCCTCGCGGGCGATCCCTCGCCGCTCATTGCAGCACAAAGGATCGTCGGAGCCAGTGAGAACA
CCACGCTGCTTGCGATCCCCTTCTTTATCTTACTGGGCAATTTGTTGAATTACACCGGTATTACCCGAAGAATGCTGACG
CTGGCGGAATTACTGACGCGCAAATTCTACGGCGGACTGGCGCAGGCCAATGTGCTACTCAGTACCTTGATGGGCGGCCT
TTCGGCCTCCAGTTTGGCGGACTGCGCCATGCTGTGCAAAATGCTGGTGCCGGAAATGACGCGCAAAGGCTACAGCAAGG
CCTTCGCTACGGTGGTGACGGCGGCGGGGTCGTTGATCACGCCAATCATCCCGCCGGGTATTGCCCTGATTATTTACGGC
TATGTGGCGGATGTGTCGATCGGCAAAATGTTTCTGGCGGGTATCGTGCCGGGAATATTGTGCTGTGCGGCGCTGATGCT
GACTATTCGCCATCTTTCCCGGCGGCGCAATTACCAGGCCAGTAATACCGATGCACCGAACTGTCGCGAGCTTGGGCAAG
CGCTGTGGCAGGCGATGCCGGCGCTTGTTCTGGTGCTGGTGATTATCGGCGGGATCCGCATCGGTGCTTTCACACCGACC
GAAGCGGGGGCGATTGCGGTGGTATTTGCCATTGGCATCGGCCTGTTTTTCACCCGTGAAATGAAGGTGGCCGATATCGG
TGAGGCCCTGTTGGATACGGCCGCTTCTACGGCGGGTATTATGCTCATTATCATGGCCTGCTCAGCATTCGCCTGGATAT
TGAGTTGGGAACGAACCGCCCAGACGGTCGCGGAGATGATTACGTCACTGTCGGATAACCCACTGTTGTTCCTGTTGGCG
CTCAACCTGTTTTTACTGGTCCTGGGGATGTTTATTGAAGGTAATGCGGCAATTATCGTGTTGGTACCGCTGCTGATGCC
AACGGTGAAGGCTCTGGGGATCGATCCGATCCAATTTGGCATTCTGATCATTCTTAACCTGGCGATTGGCAGCCTGACAC
CGCCGATGGGCACCATTATGTTTATTGCCAATTCGATTACCGGTACCCAGGTTTCTGCCTTTATCAAAGAGGTCTGGCCG
CTGTTACTGGCATTGCTGACGGTATTGCTGTTGGTGACGCTGGTACCGGCGATTTCGACCTTTTTACCTGGGCTATAG

Upstream 100 bases:

>100_bases
ACCGCTGGATCGATATGGCGATCCCGGTGGGGTCATTGCTGATGGTGCTGCAATTGGTCGTCAACCTATGTTACCGCGAC
AAACGCATGGGAGAATCATC

Downstream 100 bases:

>100_bases
CTTTGTAAACAGTGGGAGAATACTATTTCAGAAATACCACTTATGAGATCCGTTATGAGTCGGCTGCTGTTGGATCGGGA
AAAACCCGTCAAGATGCAAA

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTVAISCIILLLGFISKLPIFISVILAVLSWFFLAGDPSPLIAAQRIVGASENTTLLAIPFFILLGNLLNYTGITRRMLT
LAELLTRKFYGGLAQANVLLSTLMGGLSASSLADCAMLCKMLVPEMTRKGYSKAFATVVTAAGSLITPIIPPGIALIIYG
YVADVSIGKMFLAGIVPGILCCAALMLTIRHLSRRRNYQASNTDAPNCRELGQALWQAMPALVLVLVIIGGIRIGAFTPT
EAGAIAVVFAIGIGLFFTREMKVADIGEALLDTAASTAGIMLIIMACSAFAWILSWERTAQTVAEMITSLSDNPLLFLLA
LNLFLLVLGMFIEGNAAIIVLVPLLMPTVKALGIDPIQFGILIILNLAIGSLTPPMGTIMFIANSITGTQVSAFIKEVWP
LLLALLTVLLLVTLVPAISTFLPGL

Sequences:

>Translated_425_residues
MTVAISCIILLLGFISKLPIFISVILAVLSWFFLAGDPSPLIAAQRIVGASENTTLLAIPFFILLGNLLNYTGITRRMLT
LAELLTRKFYGGLAQANVLLSTLMGGLSASSLADCAMLCKMLVPEMTRKGYSKAFATVVTAAGSLITPIIPPGIALIIYG
YVADVSIGKMFLAGIVPGILCCAALMLTIRHLSRRRNYQASNTDAPNCRELGQALWQAMPALVLVLVIIGGIRIGAFTPT
EAGAIAVVFAIGIGLFFTREMKVADIGEALLDTAASTAGIMLIIMACSAFAWILSWERTAQTVAEMITSLSDNPLLFLLA
LNLFLLVLGMFIEGNAAIIVLVPLLMPTVKALGIDPIQFGILIILNLAIGSLTPPMGTIMFIANSITGTQVSAFIKEVWP
LLLALLTVLLLVTLVPAISTFLPGL
>Mature_424_residues
TVAISCIILLLGFISKLPIFISVILAVLSWFFLAGDPSPLIAAQRIVGASENTTLLAIPFFILLGNLLNYTGITRRMLTL
AELLTRKFYGGLAQANVLLSTLMGGLSASSLADCAMLCKMLVPEMTRKGYSKAFATVVTAAGSLITPIIPPGIALIIYGY
VADVSIGKMFLAGIVPGILCCAALMLTIRHLSRRRNYQASNTDAPNCRELGQALWQAMPALVLVLVIIGGIRIGAFTPTE
AGAIAVVFAIGIGLFFTREMKVADIGEALLDTAASTAGIMLIIMACSAFAWILSWERTAQTVAEMITSLSDNPLLFLLAL
NLFLLVLGMFIEGNAAIIVLVPLLMPTVKALGIDPIQFGILIILNLAIGSLTPPMGTIMFIANSITGTQVSAFIKEVWPL
LLALLTVLLLVTLVPAISTFLPGL

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=359, Percent_Identity=35.0974930362117, Blast_Score=193, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45067; Mature: 44936

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAISCIILLLGFISKLPIFISVILAVLSWFFLAGDPSPLIAAQRIVGASENTTLLAIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEHHHH
FFILLGNLLNYTGITRRMLTLAELLTRKFYGGLAQANVLLSTLMGGLSASSLADCAMLCK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MLVPEMTRKGYSKAFATVVTAAGSLITPIIPPGIALIIYGYVADVSIGKMFLAGIVPGIL
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CCAALMLTIRHLSRRRNYQASNTDAPNCRELGQALWQAMPALVLVLVIIGGIRIGAFTPT
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EAGAIAVVFAIGIGLFFTREMKVADIGEALLDTAASTAGIMLIIMACSAFAWILSWERTA
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTVAEMITSLSDNPLLFLLALNLFLLVLGMFIEGNAAIIVLVPLLMPTVKALGIDPIQFG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHH
ILIILNLAIGSLTPPMGTIMFIANSITGTQVSAFIKEVWPLLLALLTVLLLVTLVPAIST
HHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLPGL
HCCCC
>Mature Secondary Structure 
TVAISCIILLLGFISKLPIFISVILAVLSWFFLAGDPSPLIAAQRIVGASENTTLLAIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEHHHH
FFILLGNLLNYTGITRRMLTLAELLTRKFYGGLAQANVLLSTLMGGLSASSLADCAMLCK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MLVPEMTRKGYSKAFATVVTAAGSLITPIIPPGIALIIYGYVADVSIGKMFLAGIVPGIL
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CCAALMLTIRHLSRRRNYQASNTDAPNCRELGQALWQAMPALVLVLVIIGGIRIGAFTPT
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EAGAIAVVFAIGIGLFFTREMKVADIGEALLDTAASTAGIMLIIMACSAFAWILSWERTA
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTVAEMITSLSDNPLLFLLALNLFLLVLGMFIEGNAAIIVLVPLLMPTVKALGIDPIQFG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHH
ILIILNLAIGSLTPPMGTIMFIANSITGTQVSAFIKEVWPLLLALLTVLLLVTLVPAIST
HHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLPGL
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]