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The map label for this gene is gntK [H]

Identifier: 157372882

GI number: 157372882

Start: 5137401

End: 5137928

Strand: Reverse

Name: gntK [H]

Synonym: Spro_4650

Alternate gene names: 157372882

Gene position: 5137928-5137401 (Counterclockwise)

Preceding gene: 157372883

Following gene: 157372880

Centisome position: 94.29

GC content: 55.87

Gene sequence:

>528_bases
ATGAGCAATCCACAGCACCACGTATTTATTTTGATGGGCGTTTCCGGCAGCGGAAAATCCGCCGTGGCCAACGCCGTTGC
CCATGAGGCCAATGCCGCCATGCTGGACGGCGACTACCTGCATCCGCGTGCCAACATCAATAAAATGGCCGCCGGGCACG
CGCTGGACGATAACGATCGTGCCCCGTGGCTGGCGGCGTTGAATGACGCGATTTTTGCCATGGAGCGCACCAACGATGTT
TCACTGCTGGTCTGTTCGGCGTTGAAAAAGAGCTATCGTGACCGTCTGCGCGAAGGTAACCGCAACCTGCATTTCATCTA
TCTGAAGGGTGACAAGGCGGTGATTGAAGAGCGCCTGAAGCAGCGTAAGGGCCATTTCTTCAAGCCGCAGATGTTGGTTT
CCCAATTCGCTACTTTAGAAGAGCCGAACGAGCAAGAACAAGACGTGCAGGCGATCGAGATTGACCAACCGCTGGACGGC
GTGGTGGCCGATACCCTGGCCTATATTCGTCGTGTTGCAGCCCAGTAA

Upstream 100 bases:

>100_bases
CTGAGGTTTCCGGCACCTTGGCGGTGTCGGAAACTATTTTGAGTTTGGGGCGCATTTGATGACGCTGCCAGCGTCATCTG
ATCCCATAAGGGCATGACAT

Downstream 100 bases:

>100_bases
GCCGGGCTGCCGCCACTTCTCGGCGCCGCACTGGCGCCAGTAGCTTCACTACAACTTCATGTAAGCTCTCACGCCGTCCA
GGAACATCTGGGTCGACAGC

Product: gluconate kinase 1

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSNPQHHVFILMGVSGSGKSAVANAVAHEANAAMLDGDYLHPRANINKMAAGHALDDNDRAPWLAALNDAIFAMERTNDV
SLLVCSALKKSYRDRLREGNRNLHFIYLKGDKAVIEERLKQRKGHFFKPQMLVSQFATLEEPNEQEQDVQAIEIDQPLDG
VVADTLAYIRRVAAQ

Sequences:

>Translated_175_residues
MSNPQHHVFILMGVSGSGKSAVANAVAHEANAAMLDGDYLHPRANINKMAAGHALDDNDRAPWLAALNDAIFAMERTNDV
SLLVCSALKKSYRDRLREGNRNLHFIYLKGDKAVIEERLKQRKGHFFKPQMLVSQFATLEEPNEQEQDVQAIEIDQPLDG
VVADTLAYIRRVAAQ
>Mature_174_residues
SNPQHHVFILMGVSGSGKSAVANAVAHEANAAMLDGDYLHPRANINKMAAGHALDDNDRAPWLAALNDAIFAMERTNDVS
LLVCSALKKSYRDRLREGNRNLHFIYLKGDKAVIEERLKQRKGHFFKPQMLVSQFATLEEPNEQEQDVQAIEIDQPLDGV
VADTLAYIRRVAAQ

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=180, Percent_Identity=36.6666666666667, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI87082265, Length=170, Percent_Identity=68.8235294117647, Blast_Score=249, Evalue=7e-68,
Organism=Escherichia coli, GI1790719, Length=154, Percent_Identity=47.4025974025974, Blast_Score=154, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25146487, Length=173, Percent_Identity=38.150289017341, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320454, Length=158, Percent_Identity=39.2405063291139, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 19478; Mature: 19347

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPQHHVFILMGVSGSGKSAVANAVAHEANAAMLDGDYLHPRANINKMAAGHALDDNDR
CCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHCCCCCCCCCC
APWLAALNDAIFAMERTNDVSLLVCSALKKSYRDRLREGNRNLHFIYLKGDKAVIEERLK
CCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHH
QRKGHFFKPQMLVSQFATLEEPNEQEQDVQAIEIDQPLDGVVADTLAYIRRVAAQ
HHCCCCCCHHHHHHHHHHCCCCCCCHHCCEEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNPQHHVFILMGVSGSGKSAVANAVAHEANAAMLDGDYLHPRANINKMAAGHALDDNDR
CCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHCCCCCCCCCC
APWLAALNDAIFAMERTNDVSLLVCSALKKSYRDRLREGNRNLHFIYLKGDKAVIEERLK
CCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHH
QRKGHFFKPQMLVSQFATLEEPNEQEQDVQAIEIDQPLDGVVADTLAYIRRVAAQ
HHCCCCCCHHHHHHHHHHCCCCCCCHHCCEEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]