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The map label for this gene is tusC

Identifier: 157372785

GI number: 157372785

Start: 5029384

End: 5029743

Strand: Reverse

Name: tusC

Synonym: Spro_4553

Alternate gene names: 157372785

Gene position: 5029743-5029384 (Counterclockwise)

Preceding gene: 157372786

Following gene: 157372784

Centisome position: 92.31

GC content: 55.56

Gene sequence:

>360_bases
ATGAAACGAGTTGCTTTTGTTTTTACCCAGGGACCTCACGGCAACGCCGGCGGCAGGGAAGGGCTGGATGCGTTACTGGC
CACCTCGGCGCTGAGCGAAGATCTGGGCGTGTTTTTTATCGGTGATGGCGTATTGCAGCTATTGCCGGGGCAGCAACCGG
AAAAAATTCTGGCTCGCAATTACATCGCCACCTTTGGTGTACTGCCATTGTATGACGTTGAACGCTGCTATCTGTGCCAG
GCATCCTTGCAGGAGCGCGGTCTGAGTCAGGTAACTGACTGGGTGCTGGATGCCGAGGTATTGGCACCGGACGCGCTGGG
CCAACTATTGGCCGGCTATGATGCGGTGATGACTTTTTAG

Upstream 100 bases:

>100_bases
CCGCGGCAAACCTCCAACCGGGTTTTATCCTCAGCGGGTTGGGCTCACTGGCCGAGGCTGCGCTGAGCAGTGACCGCCTG
GTGCAGTTCTGAGAGAATTT

Downstream 100 bases:

>100_bases
GAAATCCTGATGCTGTATACCCTTAGCCGTTCCCCCACTCAATGCGATTTGCCTGCACTGCTGCGCCTGACGGCAGCGGG
CGACGACCTGCTGCTGCTAC

Product: sulfur relay protein TusC

Products: NA

Alternate protein names: tRNA 2-thiouridine synthesizing protein C

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MKRVAFVFTQGPHGNAGGREGLDALLATSALSEDLGVFFIGDGVLQLLPGQQPEKILARNYIATFGVLPLYDVERCYLCQ
ASLQERGLSQVTDWVLDAEVLAPDALGQLLAGYDAVMTF

Sequences:

>Translated_119_residues
MKRVAFVFTQGPHGNAGGREGLDALLATSALSEDLGVFFIGDGVLQLLPGQQPEKILARNYIATFGVLPLYDVERCYLCQ
ASLQERGLSQVTDWVLDAEVLAPDALGQLLAGYDAVMTF
>Mature_119_residues
MKRVAFVFTQGPHGNAGGREGLDALLATSALSEDLGVFFIGDGVLQLLPGQQPEKILARNYIATFGVLPLYDVERCYLCQ
ASLQERGLSQVTDWVLDAEVLAPDALGQLLAGYDAVMTF

Specific function: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions

COG id: COG2923

COG function: function code P; Uncharacterized protein involved in the oxidation of intracellular sulfur

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dsrF/tusC family

Homologues:

Organism=Escherichia coli, GI1789742, Length=119, Percent_Identity=63.0252100840336, Blast_Score=159, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TUSC_SERP5 (A8GKK6)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480774.1
- ProteinModelPortal:   A8GKK6
- SMR:   A8GKK6
- STRING:   A8GKK6
- GeneID:   5604661
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4553
- eggNOG:   COG2923
- HOGENOM:   HBG496129
- OMA:   FKVLPLY
- ProtClustDB:   PRK00211
- BioCyc:   SPRO399741:SPRO_4553-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00389
- InterPro:   IPR003787
- InterPro:   IPR017462
- TIGRFAMs:   TIGR03010

Pfam domain/function: PF02635 DrsE

EC number: NA

Molecular weight: Translated: 12818; Mature: 12818

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVAFVFTQGPHGNAGGREGLDALLATSALSEDLGVFFIGDGVLQLLPGQQPEKILARN
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCHHHHHHHH
YIATFGVLPLYDVERCYLCQASLQERGLSQVTDWVLDAEVLAPDALGQLLAGYDAVMTF
HHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRVAFVFTQGPHGNAGGREGLDALLATSALSEDLGVFFIGDGVLQLLPGQQPEKILARN
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCHHHHHHHH
YIATFGVLPLYDVERCYLCQASLQERGLSQVTDWVLDAEVLAPDALGQLLAGYDAVMTF
HHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA