Click here to switch to the map view.

The map label for this gene is pheC [H]

Identifier: 157372680

GI number: 157372680

Start: 4920241

End: 4921008

Strand: Direct

Name: pheC [H]

Synonym: Spro_4447

Alternate gene names: 157372680

Gene position: 4920241-4921008 (Clockwise)

Preceding gene: 157372674

Following gene: 157372683

Centisome position: 90.3

GC content: 54.04

Gene sequence:

>768_bases
ATGAAAAAATTATTACCTCTCGCACTGCTGGTTGCCGCCGGGAGCGCCAGCGCTCAATCGCACCTGGATAAGGTGATCCA
GCAGGGCACACTGGAAGTGTGCACCACCGGCGATTACAAGCCTTATACCTTCCTGAAAGAAGACGGCAGCTATGAAGGCA
TTGATATCGATATGGCGGAATCGCTGGCCAAAAGCCTGGGCGCCAAAGTGAAATGGGTAAAAACCAGTTGGAAAACCCTG
ACGCCGGACTTCGTCGCCGGTAAATGCGACATCGCCATGGGCGGCATCTCCGTCACGCTGCAGCGTCAAAGGCAGGTATT
TTTCGCCGACATGCTGGATACCGACGGCAAGATCCCATTGGTACGCTGCACCGACGTGAAGAAATACCGCACCATCGACC
AGATCAACAAACCGTCGGTGCGTCTGTTGGAGCCGGCGGGCGGTACCAACGAAGCCTTCGTGCACGCCTATCTGCCCAAG
GCCAAACTGACGCTGACCCATGATAACGTGGGGATTTTCCAGCAGTTGGTCGACAAGAAAGCCGATGTCATGATCACCGA
CGCCTCCGAGGCGCTGTATCAGCAAAAACGTTTTCCGAAACTGTGCGCGGTGAATCCCAAAAAACCGATGCAGTACGGCG
AGAAGGCCTACATGCTGCCGCGTGATGATTTAAGCTGGAAATTGTATGTGGATCAGTGGCTGCACCTGTCCAAAGCGACC
GGCGAGTATCAGAGCATTATCGATCAATGGCTGGCGGTAAAGAAATAA

Upstream 100 bases:

>100_bases
TCCAGCTGCTAATGGCATAAAAAGTGGGTAACTCGCGCAAGTCAGCGACAATTAACGCCTAAAGAGCGCATAAAACCACG
AATGTATAAAAAGGACGCCG

Downstream 100 bases:

>100_bases
CGCGTTATTGATTGGGGCCGGCAGGCGCTGGCCCCTCACAGGCTATTCGCCGATGTATTCCATCGACACGCGCTGCGTTA
GTTTGGTAATCAGTTCATAA

Product: arogenate dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKKLLPLALLVAAGSASAQSHLDKVIQQGTLEVCTTGDYKPYTFLKEDGSYEGIDIDMAESLAKSLGAKVKWVKTSWKTL
TPDFVAGKCDIAMGGISVTLQRQRQVFFADMLDTDGKIPLVRCTDVKKYRTIDQINKPSVRLLEPAGGTNEAFVHAYLPK
AKLTLTHDNVGIFQQLVDKKADVMITDASEALYQQKRFPKLCAVNPKKPMQYGEKAYMLPRDDLSWKLYVDQWLHLSKAT
GEYQSIIDQWLAVKK

Sequences:

>Translated_255_residues
MKKLLPLALLVAAGSASAQSHLDKVIQQGTLEVCTTGDYKPYTFLKEDGSYEGIDIDMAESLAKSLGAKVKWVKTSWKTL
TPDFVAGKCDIAMGGISVTLQRQRQVFFADMLDTDGKIPLVRCTDVKKYRTIDQINKPSVRLLEPAGGTNEAFVHAYLPK
AKLTLTHDNVGIFQQLVDKKADVMITDASEALYQQKRFPKLCAVNPKKPMQYGEKAYMLPRDDLSWKLYVDQWLHLSKAT
GEYQSIIDQWLAVKK
>Mature_255_residues
MKKLLPLALLVAAGSASAQSHLDKVIQQGTLEVCTTGDYKPYTFLKEDGSYEGIDIDMAESLAKSLGAKVKWVKTSWKTL
TPDFVAGKCDIAMGGISVTLQRQRQVFFADMLDTDGKIPLVRCTDVKKYRTIDQINKPSVRLLEPAGGTNEAFVHAYLPK
AKLTLTHDNVGIFQQLVDKKADVMITDASEALYQQKRFPKLCAVNPKKPMQYGEKAYMLPRDDLSWKLYVDQWLHLSKAT
GEYQSIIDQWLAVKK

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788649, Length=156, Percent_Identity=28.8461538461538, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 28563; Mature: 28563

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLPLALLVAAGSASAQSHLDKVIQQGTLEVCTTGDYKPYTFLKEDGSYEGIDIDMAE
CCCHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCEEHHHHH
SLAKSLGAKVKWVKTSWKTLTPDFVAGKCDIAMGGISVTLQRQRQVFFADMLDTDGKIPL
HHHHHHCCEEEEEECCCCCCCCCHHCCCCEEEECCEEEEEEHHHHHHHHHHHCCCCCEEE
VRCTDVKKYRTIDQINKPSVRLLEPAGGTNEAFVHAYLPKAKLTLTHDNVGIFQQLVDKK
EEECCCHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHHCCC
ADVMITDASEALYQQKRFPKLCAVNPKKPMQYGEKAYMLPRDDLSWKLYVDQWLHLSKAT
CCEEEECHHHHHHHHHCCCCEECCCCCCCHHCCCEEEECCCCCCCEEEEEHHHHHHHHCC
GEYQSIIDQWLAVKK
CHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKLLPLALLVAAGSASAQSHLDKVIQQGTLEVCTTGDYKPYTFLKEDGSYEGIDIDMAE
CCCHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCEEHHHHH
SLAKSLGAKVKWVKTSWKTLTPDFVAGKCDIAMGGISVTLQRQRQVFFADMLDTDGKIPL
HHHHHHCCEEEEEECCCCCCCCCHHCCCCEEEECCEEEEEEHHHHHHHHHHHCCCCCEEE
VRCTDVKKYRTIDQINKPSVRLLEPAGGTNEAFVHAYLPKAKLTLTHDNVGIFQQLVDKK
EEECCCHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHHCCC
ADVMITDASEALYQQKRFPKLCAVNPKKPMQYGEKAYMLPRDDLSWKLYVDQWLHLSKAT
CCEEEECHHHHHHHHHCCCCEECCCCCCCHHCCCEEEECCCCCCCEEEEEHHHHHHHHCC
GEYQSIIDQWLAVKK
CHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]