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The map label for this gene is qorA [H]

Identifier: 157372683

GI number: 157372683

Start: 4923750

End: 4924739

Strand: Direct

Name: qorA [H]

Synonym: Spro_4450

Alternate gene names: 157372683

Gene position: 4923750-4924739 (Clockwise)

Preceding gene: 157372680

Following gene: 157372684

Centisome position: 90.36

GC content: 58.79

Gene sequence:

>990_bases
ATGGCAAAGCGCATTCAATTCTCCGCCACCGGCGGCCCGGAAGTCTTGCAATATGTTGATTTTACCCCCGTAGATCCGGC
AGCCGGTGAGGTGCAGATCGAGAACAAGGCGATCGGTATCAACTATATCGACACCTACGTGCGCAGCGGTCTGTATCCGC
CCGCCAAACTACCGAGCGGATTGGGTACCGAGGCGGCCGGGGTGGTGATCAAGGTCGGTGCCGGTGTCAGCGTGCTAAAA
CCGGGTGACCGGGTGGTGTATGCCCAGTCGACGCTTGGAGCCTACAGCGAAGTGCATAACGTTTCGCAGGAAAAAGTGGC
ATTGCTGCCGCATAACCTGAGTTTTGAGCAGGGCGCGGCCTCCTTCCTGAAAGGGCTGACGGTGCATTATTTGCTGCGCC
AAACCCATGAGGTGCAACCGGGTGAAGTGTTCCTGTTCCATGCCGCCGCAGGGGGCGTTGGGCTGATTGCCTGCCAGTGG
GCGAAAGCGCTCGGGGCAAAACTGATCGGCAGCGTCGGCTCCGACGAAAAAGCCGAGCTGGCGAAGCACGCAGGCGCATG
GGCAACCATCAATTACCATAAGGAAGATATCGCCCAGCGCGTGGCTGAGCTGACACAGGGTGAGAAAGTCGGCGTCGTTT
ACGACTCGGTAGGCCAAAGTACCTGGCAGGCCTCACTTAACAGCCTGAAACGCCGTGGGCTAATGGTGAGCTTCGGCAAT
GCGTCCGGCCCGGTCACCGGCGTCGATCTGGCGTTGCTGAACCAAAAAGGCTCGCTGTACGTCACCCGCCCTTCGCTTAA
CGGCTACATTACCACCCGTGCTGAACTGCAGTATGCCAGCAATGAGCTGTTTTCCTTGATCGGCAGCGGGGCTATCAAAG
TCGACGTGAAGGAAGAGCAAAAGTTTGCGTTGGCCGATGCACAGCGCGCCCATCAGGTGCTGGAAAGCCGCAACACCAGC
GGTTCAAGCTTGCTGATCCCCGGTCGCTGA

Upstream 100 bases:

>100_bases
GCATAACAGATGCAAAAAGTATCAAGCCACCCCAGGGCAAACTGGATCGCCGATGCTAAAACGCGTAGGGTGAAATCAGA
CCCCCACTCGAGGTAATGAA

Downstream 100 bases:

>100_bases
GATGAGTACCCTTACAAACACAAGGTAATACAAAGCACTGTATCGCATCGAAAAATCATTACTAAAGGAATATGATCTTC
TGGTAATTCATATTGATCAA

Product: NADPH-dependent quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAKRIQFSATGGPEVLQYVDFTPVDPAAGEVQIENKAIGINYIDTYVRSGLYPPAKLPSGLGTEAAGVVIKVGAGVSVLK
PGDRVVYAQSTLGAYSEVHNVSQEKVALLPHNLSFEQGAASFLKGLTVHYLLRQTHEVQPGEVFLFHAAAGGVGLIACQW
AKALGAKLIGSVGSDEKAELAKHAGAWATINYHKEDIAQRVAELTQGEKVGVVYDSVGQSTWQASLNSLKRRGLMVSFGN
ASGPVTGVDLALLNQKGSLYVTRPSLNGYITTRAELQYASNELFSLIGSGAIKVDVKEEQKFALADAQRAHQVLESRNTS
GSSLLIPGR

Sequences:

>Translated_329_residues
MAKRIQFSATGGPEVLQYVDFTPVDPAAGEVQIENKAIGINYIDTYVRSGLYPPAKLPSGLGTEAAGVVIKVGAGVSVLK
PGDRVVYAQSTLGAYSEVHNVSQEKVALLPHNLSFEQGAASFLKGLTVHYLLRQTHEVQPGEVFLFHAAAGGVGLIACQW
AKALGAKLIGSVGSDEKAELAKHAGAWATINYHKEDIAQRVAELTQGEKVGVVYDSVGQSTWQASLNSLKRRGLMVSFGN
ASGPVTGVDLALLNQKGSLYVTRPSLNGYITTRAELQYASNELFSLIGSGAIKVDVKEEQKFALADAQRAHQVLESRNTS
GSSLLIPGR
>Mature_328_residues
AKRIQFSATGGPEVLQYVDFTPVDPAAGEVQIENKAIGINYIDTYVRSGLYPPAKLPSGLGTEAAGVVIKVGAGVSVLKP
GDRVVYAQSTLGAYSEVHNVSQEKVALLPHNLSFEQGAASFLKGLTVHYLLRQTHEVQPGEVFLFHAAAGGVGLIACQWA
KALGAKLIGSVGSDEKAELAKHAGAWATINYHKEDIAQRVAELTQGEKVGVVYDSVGQSTWQASLNSLKRRGLMVSFGNA
SGPVTGVDLALLNQKGSLYVTRPSLNGYITTRAELQYASNELFSLIGSGAIKVDVKEEQKFALADAQRAHQVLESRNTSG
SSLLIPGR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=242, Percent_Identity=30.9917355371901, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI13236495, Length=242, Percent_Identity=30.9917355371901, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=34.9753694581281, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI18379349, Length=323, Percent_Identity=31.2693498452012, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=29.0909090909091, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=29.0909090909091, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI28557745, Length=290, Percent_Identity=27.9310344827586, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI24308257, Length=225, Percent_Identity=30.6666666666667, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI67078404, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=72.4770642201835, Blast_Score=492, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17507255, Length=233, Percent_Identity=30.0429184549356, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17536829, Length=257, Percent_Identity=30.3501945525292, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=330, Percent_Identity=40, Blast_Score=202, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6324486, Length=312, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=266, Percent_Identity=28.9473684210526, Blast_Score=82, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=325, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=253, Percent_Identity=26.8774703557312, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550423, Length=303, Percent_Identity=24.4224422442244, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34917; Mature: 34786

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRIQFSATGGPEVLQYVDFTPVDPAAGEVQIENKAIGINYIDTYVRSGLYPPAKLPSG
CCCEEEEECCCCHHHHHCCCCCCCCCCCCEEEECCEEEEHHHHHHHHHCCCCCCHHCCCC
LGTEAAGVVIKVGAGVSVLKPGDRVVYAQSTLGAYSEVHNVSQEKVALLPHNLSFEQGAA
CCCCCCCEEEEECCCEEEECCCCEEEEECHHHHHHHHHHCCCCHHEEECCCCCCHHHHHH
SFLKGLTVHYLLRQTHEVQPGEVFLFHAAAGGVGLIACQWAKALGAKLIGSVGSDEKAEL
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
AKHAGAWATINYHKEDIAQRVAELTQGEKVGVVYDSVGQSTWQASLNSLKRRGLMVSFGN
HHHCCCEEEEEECHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEECC
ASGPVTGVDLALLNQKGSLYVTRPSLNGYITTRAELQYASNELFSLIGSGAIKVDVKEEQ
CCCCCCEEEEEEECCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEECCCC
KFALADAQRAHQVLESRNTSGSSLLIPGR
HHHHHHHHHHHHHHHHCCCCCCEEEECCC
>Mature Secondary Structure 
AKRIQFSATGGPEVLQYVDFTPVDPAAGEVQIENKAIGINYIDTYVRSGLYPPAKLPSG
CCEEEEECCCCHHHHHCCCCCCCCCCCCEEEECCEEEEHHHHHHHHHCCCCCCHHCCCC
LGTEAAGVVIKVGAGVSVLKPGDRVVYAQSTLGAYSEVHNVSQEKVALLPHNLSFEQGAA
CCCCCCCEEEEECCCEEEECCCCEEEEECHHHHHHHHHHCCCCHHEEECCCCCCHHHHHH
SFLKGLTVHYLLRQTHEVQPGEVFLFHAAAGGVGLIACQWAKALGAKLIGSVGSDEKAEL
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
AKHAGAWATINYHKEDIAQRVAELTQGEKVGVVYDSVGQSTWQASLNSLKRRGLMVSFGN
HHHCCCEEEEEECHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEECC
ASGPVTGVDLALLNQKGSLYVTRPSLNGYITTRAELQYASNELFSLIGSGAIKVDVKEEQ
CCCCCCEEEEEEECCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEECCCC
KFALADAQRAHQVLESRNTSGSSLLIPGR
HHHHHHHHHHHHHHHHCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]