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The map label for this gene is mlaB [H]

Identifier: 157372589

GI number: 157372589

Start: 4828215

End: 4828514

Strand: Reverse

Name: mlaB [H]

Synonym: Spro_4356

Alternate gene names: 157372589

Gene position: 4828514-4828215 (Counterclockwise)

Preceding gene: 157372590

Following gene: 157372588

Centisome position: 88.62

GC content: 53.67

Gene sequence:

>300_bases
ATGACCGCACTCAGCTTTGAATCGCAGCAGCAGACTCTGATCCTGCGCGGTGAACTGGATCGGGAAACTCTGTTGCCGCT
GTGGGAACAGCGGGAAACGTTGCTGGCGGATATAACTGTCCTCGACGTTACGCAATTGCAGCGTGTGGACTCTTCCGGGC
TGGCATTGCTGGTACATCTGCGTGAACAGCAGCGTCAGCACGGCGTGGAATTAAAAATTTCTGGTGCCAGCGATCGCCTG
AAAACCTTGATCACACTGTACAACCTGCAAGCAATAATGCCTGTCGATACCGCTGGTTAG

Upstream 100 bases:

>100_bases
ACGAGTGGGCATCTACCTTGCGTACCCAAGGGATTGACGGCCTGACCAAACAACTGCAGGCGGCGGCGCAGCGTCCAATC
ACGCTGGATCAGAAAAACTG

Downstream 100 bases:

>100_bases
CCCTACTTTCGGCTGGTTAAAGACGGTTTCGCCTCAGAAAGCCCCTGTTACACAGGGGCTTTTTCTTTAGTTTAAGAAAA
CGTCTGATTCCACTAAGATG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 99; Mature: 98

Protein sequence:

>99_residues
MTALSFESQQQTLILRGELDRETLLPLWEQRETLLADITVLDVTQLQRVDSSGLALLVHLREQQRQHGVELKISGASDRL
KTLITLYNLQAIMPVDTAG

Sequences:

>Translated_99_residues
MTALSFESQQQTLILRGELDRETLLPLWEQRETLLADITVLDVTQLQRVDSSGLALLVHLREQQRQHGVELKISGASDRL
KTLITLYNLQAIMPVDTAG
>Mature_98_residues
TALSFESQQQTLILRGELDRETLLPLWEQRETLLADITVLDVTQLQRVDSSGLALLVHLREQQRQHGVELKISGASDRLK
TLITLYNLQAIMPVDTAG

Specific function: Part of the ABC transporter complex mlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner memb

COG id: COG3113

COG function: function code R; Predicted NTP binding protein (contains STAS domain)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Escherichia coli, GI87082227, Length=93, Percent_Identity=44.0860215053763, Blast_Score=70, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 11153; Mature: 11022

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALSFESQQQTLILRGELDRETLLPLWEQRETLLADITVLDVTQLQRVDSSGLALLVHL
CCCCCCCCCCCEEEEECCCCCHHHCCCHHCCHHHHHHHHHCCHHHHHHCCCCCEEEEEEE
REQQRQHGVELKISGASDRLKTLITLYNLQAIMPVDTAG
HHHHHHCCCEEEECCCHHHHHHHHHHHCCEEEEEECCCC
>Mature Secondary Structure 
TALSFESQQQTLILRGELDRETLLPLWEQRETLLADITVLDVTQLQRVDSSGLALLVHL
CCCCCCCCCCEEEEECCCCCHHHCCCHHCCHHHHHHHHHCCHHHHHHCCCCCEEEEEEE
REQQRQHGVELKISGASDRLKTLITLYNLQAIMPVDTAG
HHHHHHCCCEEEECCCHHHHHHHHHHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]