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The map label for this gene is mlaC [H]

Identifier: 157372590

GI number: 157372590

Start: 4828514

End: 4829143

Strand: Reverse

Name: mlaC [H]

Synonym: Spro_4357

Alternate gene names: 157372590

Gene position: 4829143-4828514 (Counterclockwise)

Preceding gene: 157372591

Following gene: 157372589

Centisome position: 88.63

GC content: 55.08

Gene sequence:

>630_bases
ATGTTTAAACGTTTACTTATGGTTGCCCTGCTGGTGGTTGCGCCGCTGGCGAACGCGGTCGATCAAACCAATCCTTACAG
CCTGATGCAGGACGCGGCTCAAAAGACCTTTAACCGTCTGAAAACCGAGCAGCCGAAAATCAAGCAGGATCCCAACTACC
TGCGTTCCGTGGTGCATCAGGAGTTGATGCCTTTTGTACAGGTTAAATACGCCGGTGCACTGGTACTGGGCCGTTATTAC
AAAGAAGCGACCCCGGCGCAGCGTGAAGCTTACTTCACCGCATTCCAGGCCTACCTGGAACAGGCCTACGGCCAGGCGTT
GGCGATGTACCACGGCCAGACTTACCAGATTGAACCTGAAAAGCCGTTGGATAATGCTGATATCGTCGCCATCCGCGTGA
CCATCATTGACCAGGGCGGTCGCCCGCCGGTGCGTCTGGACTTCCAGTGGCGCAAAAACAGCAAGACCGGTTACTGGCAG
GCGTATGACATGATCGCCGAAGGCGTCAGTATGATTACCACCAAGCAAAACGAGTGGGCATCTACCTTGCGTACCCAAGG
GATTGACGGCCTGACCAAACAACTGCAGGCGGCGGCGCAGCGTCCAATCACGCTGGATCAGAAAAACTGA

Upstream 100 bases:

>100_bases
GCCAGGATAACGCAGATAAAGCGGGAGACGCGGCTGCCAGCCCGGCTGCCGGTACTGCGCCGCAACCTGCTGCCCCCATT
CATTAAGAGAGGAAGCCTGC

Downstream 100 bases:

>100_bases
TGACCGCACTCAGCTTTGAATCGCAGCAGCAGACTCTGATCCTGCGCGGTGAACTGGATCGGGAAACTCTGTTGCCGCTG
TGGGAACAGCGGGAAACGTT

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MFKRLLMVALLVVAPLANAVDQTNPYSLMQDAAQKTFNRLKTEQPKIKQDPNYLRSVVHQELMPFVQVKYAGALVLGRYY
KEATPAQREAYFTAFQAYLEQAYGQALAMYHGQTYQIEPEKPLDNADIVAIRVTIIDQGGRPPVRLDFQWRKNSKTGYWQ
AYDMIAEGVSMITTKQNEWASTLRTQGIDGLTKQLQAAAQRPITLDQKN

Sequences:

>Translated_209_residues
MFKRLLMVALLVVAPLANAVDQTNPYSLMQDAAQKTFNRLKTEQPKIKQDPNYLRSVVHQELMPFVQVKYAGALVLGRYY
KEATPAQREAYFTAFQAYLEQAYGQALAMYHGQTYQIEPEKPLDNADIVAIRVTIIDQGGRPPVRLDFQWRKNSKTGYWQ
AYDMIAEGVSMITTKQNEWASTLRTQGIDGLTKQLQAAAQRPITLDQKN
>Mature_209_residues
MFKRLLMVALLVVAPLANAVDQTNPYSLMQDAAQKTFNRLKTEQPKIKQDPNYLRSVVHQELMPFVQVKYAGALVLGRYY
KEATPAQREAYFTAFQAYLEQAYGQALAMYHGQTYQIEPEKPLDNADIVAIRVTIIDQGGRPPVRLDFQWRKNSKTGYWQ
AYDMIAEGVSMITTKQNEWASTLRTQGIDGLTKQLQAAAQRPITLDQKN

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=210, Percent_Identity=75.7142857142857, Blast_Score=333, Evalue=6e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23806; Mature: 23806

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRLLMVALLVVAPLANAVDQTNPYSLMQDAAQKTFNRLKTEQPKIKQDPNYLRSVVHQ
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ELMPFVQVKYAGALVLGRYYKEATPAQREAYFTAFQAYLEQAYGQALAMYHGQTYQIEPE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
KPLDNADIVAIRVTIIDQGGRPPVRLDFQWRKNSKTGYWQAYDMIAEGVSMITTKQNEWA
CCCCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHCCHHHHHCCCHHHH
STLRTQGIDGLTKQLQAAAQRPITLDQKN
HHHHHCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFKRLLMVALLVVAPLANAVDQTNPYSLMQDAAQKTFNRLKTEQPKIKQDPNYLRSVVHQ
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ELMPFVQVKYAGALVLGRYYKEATPAQREAYFTAFQAYLEQAYGQALAMYHGQTYQIEPE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
KPLDNADIVAIRVTIIDQGGRPPVRLDFQWRKNSKTGYWQAYDMIAEGVSMITTKQNEWA
CCCCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHCCHHHHHCCCHHHH
STLRTQGIDGLTKQLQAAAQRPITLDQKN
HHHHHCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]