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The map label for this gene is dhaL [H]

Identifier: 157372504

GI number: 157372504

Start: 4736468

End: 4737100

Strand: Reverse

Name: dhaL [H]

Synonym: Spro_4271

Alternate gene names: 157372504

Gene position: 4737100-4736468 (Counterclockwise)

Preceding gene: 157372505

Following gene: 157372503

Centisome position: 86.94

GC content: 60.35

Gene sequence:

>633_bases
ATGGCGTTAACCAAACAACAAGTGGTCGACTGGCTGATGCGCTGCGGCGAGGTATTTACTCAGCAGCGTGATTTTTTAAC
CCGGCTGGATACCGAGATCGGTGATTCCGACCACGGGCTGAACATGAACCGCGGCTTCAACAAGGTAGTGGAAAAACTGC
CTTCGGTGGCAGACAAAGACATCGGTTTTATCCTGAAGAACACCGGCATGACGCTGCTGTCCAGCGTCGGAGGAGCCAGC
GGCCCGCTGTTCGGCACCTTCTTCATCCGCGCTGCGCAGTCGACCAATGCCAAGCAGAGCCTGGATCTGGCGGAGCTGCA
TCAAATGATGCAGGAAGGCGTCGAAGGCGTGGTGATGCGCGGCAAGGCGGAGCCGGGTGATAAAACCATGTGTGACGTCT
GGTGGCCGGTGGTGGAAAGCCTGGGCCAGTCGGCCGAGCAGCAGCTAAGCGTGGCGGAGGCCTTGCAGCGCGCCAGTGAC
CGGGCGGAGCAGGCGGTTGAAAGCACCATCACCATGCAGGCACGCAAAGGGCGGGCCAGTTACCTGGGTGAGCGCAGCAT
CGGCCATCAGGATCCGGGTGCCACCTCGGTGATGCTGATGATGAAAACGTTGGCAGCGGTCGCCGGCCAATAG

Upstream 100 bases:

>100_bases
GGTCTCAATCACGCTGCTGAAAGTGGACGATGAACTGTTGTCCCTGTGGGATGCGCCGGTGAAAACGCCTGCGCTGCGTT
GGGGTTGCTGAGGAGGAATC

Downstream 100 bases:

>100_bases
CAGGAGGCGAGATGATCAATATCGTTGTAGTTTCACACAGCGCGCTGTTGGCGCGCGGGGTTGAAGAGCTGGCGTTGCAG
ATGATGCGTGGCGATGGCTG

Product: dihydroxyacetone kinase subunit L

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MALTKQQVVDWLMRCGEVFTQQRDFLTRLDTEIGDSDHGLNMNRGFNKVVEKLPSVADKDIGFILKNTGMTLLSSVGGAS
GPLFGTFFIRAAQSTNAKQSLDLAELHQMMQEGVEGVVMRGKAEPGDKTMCDVWWPVVESLGQSAEQQLSVAEALQRASD
RAEQAVESTITMQARKGRASYLGERSIGHQDPGATSVMLMMKTLAAVAGQ

Sequences:

>Translated_210_residues
MALTKQQVVDWLMRCGEVFTQQRDFLTRLDTEIGDSDHGLNMNRGFNKVVEKLPSVADKDIGFILKNTGMTLLSSVGGAS
GPLFGTFFIRAAQSTNAKQSLDLAELHQMMQEGVEGVVMRGKAEPGDKTMCDVWWPVVESLGQSAEQQLSVAEALQRASD
RAEQAVESTITMQARKGRASYLGERSIGHQDPGATSVMLMMKTLAAVAGQ
>Mature_209_residues
ALTKQQVVDWLMRCGEVFTQQRDFLTRLDTEIGDSDHGLNMNRGFNKVVEKLPSVADKDIGFILKNTGMTLLSSVGGASG
PLFGTFFIRAAQSTNAKQSLDLAELHQMMQEGVEGVVMRGKAEPGDKTMCDVWWPVVESLGQSAEQQLSVAEALQRASDR
AEQAVESTITMQARKGRASYLGERSIGHQDPGATSVMLMMKTLAAVAGQ

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sens

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=196, Percent_Identity=33.6734693877551, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1787449, Length=208, Percent_Identity=75, Blast_Score=318, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6323570, Length=203, Percent_Identity=23.1527093596059, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 22825; Mature: 22694

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTKQQVVDWLMRCGEVFTQQRDFLTRLDTEIGDSDHGLNMNRGFNKVVEKLPSVADKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCH
IGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQSTNAKQSLDLAELHQMMQEGVEGVVMR
HHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHEECC
GKAEPGDKTMCDVWWPVVESLGQSAEQQLSVAEALQRASDRAEQAVESTITMQARKGRAS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
YLGERSIGHQDPGATSVMLMMKTLAAVAGQ
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALTKQQVVDWLMRCGEVFTQQRDFLTRLDTEIGDSDHGLNMNRGFNKVVEKLPSVADKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCH
IGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQSTNAKQSLDLAELHQMMQEGVEGVVMR
HHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHEECC
GKAEPGDKTMCDVWWPVVESLGQSAEQQLSVAEALQRASDRAEQAVESTITMQARKGRAS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
YLGERSIGHQDPGATSVMLMMKTLAAVAGQ
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]