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The map label for this gene is rlmM

Identifier: 157372038

GI number: 157372038

Start: 4203571

End: 4204674

Strand: Reverse

Name: rlmM

Synonym: Spro_3803

Alternate gene names: 157372038

Gene position: 4204674-4203571 (Counterclockwise)

Preceding gene: 157372039

Following gene: 157372034

Centisome position: 77.17

GC content: 55.07

Gene sequence:

>1104_bases
ATGAATAGACTTGCGTTGTATTGCCGTCAAGGCTTTGAAAAAGAGTGTGCGGCAGAAATTACCGCCAAGGCTGCCGAACT
GGAAGTGTTCGGTTTTGCCAGAGTAAAGGATAACAGCGGCTACGTGCTGTTCGAGTGCTACCAGCCGGATGACGCCGATC
GCCTGGCGAAGGAAATCCCGTTCCGGGAGCTGATTTTTGCCCGTCAGATATTGGTGGTTGGCGAGTTGCTGCGCGATTTA
CCACCGGAAGATCGGGTTTCTCCGATTGTCGGCATGCTGATTGGCGTGGTCGATCGTGGTGGTGAGCTGCGAGTGGAAGT
GCCGGATACCAACGAAAGCAAAGAACTGTTGAAGTTCTGCCGCAAGCTGACGGTGCCGTTGCGTACTGCGATGCGTGAGC
AGAAGGTGTTGATGGCGCGTGAGAATAAGACCCGTCCAGTGGTGCATGTGTTCTTTATCGCTCCGGGGTGTTGCTATGTG
GGTTACTCCTTCAGCAACAACAATTCACCGTTCTATATGGGCATTCCGCGTCTCAAGTTCCCATCCGATGCACCGAGCCG
TTCTACCCTGAAACTGGAAGAAGCGTTCCACGTGTTCATTCCTGCCGACGAGTGGGATGAACGTTTGGCCAGCGGCATGC
ACGCGGTCGATCTGGGCGCCTGTCCGGGTGGCTGGACCTATCAACTGGTGCAACGCAGCATGATGGTGCACGCGGTGGAC
AATGGCCCAATGGCACCGAGCCTGATGGATACCGGGCAGGTGACGCATCATCGTGCCGACGGTTTCAGATATGAGCCTTC
CAGCAGCAAGATTTACTGGCTGGTGTGCGATATGGTGGAAAAACCGGCGAAGGTGACCAGCCTGATGATCCAGTGGCTGG
TGAAAGGCTGGTGTCGTGAGGCGATCTTCAACCTGAAATTGCCGATGAAAAAACGTTACGAAGAGGTTTCGCAGAATCTG
CTGGCCATCAAGGAAGCGTTGGATACGGCGGGTATCAGTTCAGAAATTCATGCCAAGCAGCTGTATCACGATCGTGAAGA
AGTCACCGTGCACGTCCGTCGTATGTGGTCGGCCGTGGCAGGCCGCCGCGACGAGCGCGATTAA

Upstream 100 bases:

>100_bases
TTCTGGGTTTATATCACGCCGATTGGCGGCGTGTGTTTCCTGATCGGTTGGGTATTGATGTTGATTGGCGCTTTGCGTCT
GAGGAAAAAGGCCGAGCGCC

Downstream 100 bases:

>100_bases
ATGACAGGGCGCTGTCTTCAGCGCCAGTGATTAAACCGGTAACCGCAGTTGCTGCAGGTTGCCGGTTAATGCCAGATCGG
TTCGCAAGGTAGCGACTCTT

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNRLALYCRQGFEKECAAEITAKAAELEVFGFARVKDNSGYVLFECYQPDDADRLAKEIPFRELIFARQILVVGELLRDL
PPEDRVSPIVGMLIGVVDRGGELRVEVPDTNESKELLKFCRKLTVPLRTAMREQKVLMARENKTRPVVHVFFIAPGCCYV
GYSFSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWDERLASGMHAVDLGACPGGWTYQLVQRSMMVHAVD
NGPMAPSLMDTGQVTHHRADGFRYEPSSSKIYWLVCDMVEKPAKVTSLMIQWLVKGWCREAIFNLKLPMKKRYEEVSQNL
LAIKEALDTAGISSEIHAKQLYHDREEVTVHVRRMWSAVAGRRDERD

Sequences:

>Translated_367_residues
MNRLALYCRQGFEKECAAEITAKAAELEVFGFARVKDNSGYVLFECYQPDDADRLAKEIPFRELIFARQILVVGELLRDL
PPEDRVSPIVGMLIGVVDRGGELRVEVPDTNESKELLKFCRKLTVPLRTAMREQKVLMARENKTRPVVHVFFIAPGCCYV
GYSFSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWDERLASGMHAVDLGACPGGWTYQLVQRSMMVHAVD
NGPMAPSLMDTGQVTHHRADGFRYEPSSSKIYWLVCDMVEKPAKVTSLMIQWLVKGWCREAIFNLKLPMKKRYEEVSQNL
LAIKEALDTAGISSEIHAKQLYHDREEVTVHVRRMWSAVAGRRDERD
>Mature_367_residues
MNRLALYCRQGFEKECAAEITAKAAELEVFGFARVKDNSGYVLFECYQPDDADRLAKEIPFRELIFARQILVVGELLRDL
PPEDRVSPIVGMLIGVVDRGGELRVEVPDTNESKELLKFCRKLTVPLRTAMREQKVLMARENKTRPVVHVFFIAPGCCYV
GYSFSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWDERLASGMHAVDLGACPGGWTYQLVQRSMMVHAVD
NGPMAPSLMDTGQVTHHRADGFRYEPSSSKIYWLVCDMVEKPAKVTSLMIQWLVKGWCREAIFNLKLPMKKRYEEVSQNL
LAIKEALDTAGISSEIHAKQLYHDREEVTVHVRRMWSAVAGRRDERD

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily

Homologues:

Organism=Escherichia coli, GI1789171, Length=366, Percent_Identity=76.5027322404372, Blast_Score=603, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMM_SERP5 (A8GIF9)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480027.1
- ProteinModelPortal:   A8GIF9
- SMR:   A8GIF9
- STRING:   A8GIF9
- GeneID:   5606968
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3803
- eggNOG:   COG2933
- HOGENOM:   HBG681972
- OMA:   LYCRPGF
- ProtClustDB:   PRK11760
- BioCyc:   SPRO399741:SPRO_3803-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01551
- InterPro:   IPR011224
- InterPro:   IPR002877
- PIRSF:   PIRSF028774

Pfam domain/function: PF01728 FtsJ

EC number: NA

Molecular weight: Translated: 41807; Mature: 41807

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLALYCRQGFEKECAAEITAKAAELEVFGFARVKDNSGYVLFECYQPDDADRLAKEIP
CCCCHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHCC
FRELIFARQILVVGELLRDLPPEDRVSPIVGMLIGVVDRGGELRVEVPDTNESKELLKFC
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
RKLTVPLRTAMREQKVLMARENKTRPVVHVFFIAPGCCYVGYSFSNNNSPFYMGIPRLKF
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCCCCEEECCCCCCC
PSDAPSRSTLKLEEAFHVFIPADEWDERLASGMHAVDLGACPGGWTYQLVQRSMMVHAVD
CCCCCCCCEEEEECCEEEEECCCHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHEEEEC
NGPMAPSLMDTGQVTHHRADGFRYEPSSSKIYWLVCDMVEKPAKVTSLMIQWLVKGWCRE
CCCCCCCHHCCCCCHHCCCCCEEECCCCCEEEEEEECHHHCHHHHHHHHHHHHHHHHHHH
AIFNLKLPMKKRYEEVSQNLLAIKEALDTAGISSEIHAKQLYHDREEVTVHVRRMWSAVA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
GRRDERD
CCCCCCC
>Mature Secondary Structure
MNRLALYCRQGFEKECAAEITAKAAELEVFGFARVKDNSGYVLFECYQPDDADRLAKEIP
CCCCHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHCC
FRELIFARQILVVGELLRDLPPEDRVSPIVGMLIGVVDRGGELRVEVPDTNESKELLKFC
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
RKLTVPLRTAMREQKVLMARENKTRPVVHVFFIAPGCCYVGYSFSNNNSPFYMGIPRLKF
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCCCCEEECCCCCCC
PSDAPSRSTLKLEEAFHVFIPADEWDERLASGMHAVDLGACPGGWTYQLVQRSMMVHAVD
CCCCCCCCEEEEECCEEEEECCCHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHEEEEC
NGPMAPSLMDTGQVTHHRADGFRYEPSSSKIYWLVCDMVEKPAKVTSLMIQWLVKGWCRE
CCCCCCCHHCCCCCHHCCCCCEEECCCCCEEEEEEECHHHCHHHHHHHHHHHHHHHHHHH
AIFNLKLPMKKRYEEVSQNLLAIKEALDTAGISSEIHAKQLYHDREEVTVHVRRMWSAVA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
GRRDERD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA