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The map label for this gene is tmcA [H]

Identifier: 157371742

GI number: 157371742

Start: 3879907

End: 3881919

Strand: Reverse

Name: tmcA [H]

Synonym: Spro_3505

Alternate gene names: 157371742

Gene position: 3881919-3879907 (Counterclockwise)

Preceding gene: 157371743

Following gene: 157371741

Centisome position: 71.24

GC content: 62.89

Gene sequence:

>2013_bases
ATGTTACAGGCAATGCAACAACTTATGCAGCAGCAGGGCATCAGACGCCTGCTGGTGCTCAGTGGCGAGCCGCAATGGTG
TCGCCAGCAAGCGCACCGGCTGGCGACAACCCTGCCGGGTGACTGGCCGTGGGTGGGGGAAAACCCGCCCAGCGGCATGC
AGTCGCTGGCCAGTGGTGCGGTACGGACATTGCTGGGGCAGGAACGATTACATGCCGTGTATGACGCGACCGATGGTTTG
GATGTTGAAGCGCTGGCCGCGCTGGCCGGTACGCTGCGAGCCGGCAGTTGGTTGTTGCTGTTAACCCCACCCTGGCAGTC
CTGGCACCAACAGCCGGATAGCGACAGCCTGCGCTGGAGCGATTGCCCACAGCCGATCACTACCCCAAACTTCATTCACC
ATCTGCAGCAACACTTGGCGGCGGACAGCGAAGTCACGCTCTGGCGACAGGATGAGCCGCTGACGTTGGCACCTTTGCCG
GTCCGCCCGCAGTGGCAAGCGCCGAATGGCCAACCGACTTTCGAGCAGCAAGCGTTGTTGACGCAATTACTCGGCGCCGA
GCCAGGCGTTTGGGTGCTGACCGCCGCCCGTGGGCGCGGCAAGTCAACGCTGGCGGGGATGCTGGTGGCCAACACGCCGC
TGACCTGCTGGCTCACCGGGCCCAGCCGAGCGGCTACCGAGGTTGCTGGTGAATGGGCACAGGGCCGTGCGCAATTCTGG
GCACCGGACGCGCTGCTGGCCCATTGTCGCGAACATGATGTCAGCGACGTGGGCTGGCTGTTGGTGGACGAGGCGGCGGC
GATCCCCGGCCCGTTATTACGGCAGTGGGTTAACCATTTCCCCCGCATTCTGCTGACGACCACGGTACAGGGCTATGAAG
GCACTGGCCGGGGTTTCTTGCTCAAGTTTTGCGCCGGGCTGCCTGAGTTTCAGCCGCTGGAGTTGCAGCAACCCATGCGT
TGGGCGCCGGGTGATGCGCTGGAGCGTGTCATCGATAACGCGCTGCTGTTCAACGAACTCCCGCCGTGGCAGGCAACGGA
TCGCCCCGTCAGTATCACTGGAGCTGAACAAAGGGCGCTGTGTGCCGATCCTCAACGCTTAGTGCGTTTTTACGCCCTGT
TGAGCAGCGCCCATTACCGGACTTCACCGCTCGATTTACGGCGGTTGATGGATGCACCGGGTATGCATTTTGGCCTGGCG
CAGGTTGAGGATGAGGTCGTCGGCGCGTTGTGGCTGGTAGAAGAAGGCGGCCTGAGTGCCGAACTGGCGCACGAAGTCTG
GGCCGGCAGGCGGCGACCACGTGGCAATCTGGTGGCCCAATCGTTGGCGGCGCACGGTGGCCAGTGGTGGGCACCGACGC
TGCGTTCAAGACGCATTACCCGCATTGCGGTATTACCCGCTATGCGTCAGCAGGGCATCGCCCGCAGGCTGATCGAGCAG
CAGCGTCAGCAGGCACAAGGGTTGGATTATCTTTCGGTCAGCTTTGGTTACACCGAGCCGCTGTGGCGCTTTTGGCAGTC
CTGTGGCTTTGAGCTGGCGCGTATTGGCAGCAAGATCGAAGCCAGCAGCGGCTGCTACAGCGTCATGGCCATTCTGCCCT
TGAGCGAGCAGGGTGAGGCGCTGCGTCATGCGGCACACAAGCATCTGGCGCGTGATTGGCGCTGGTTGCAGCCGCGCATC
GATCTGCAACTGGAAGTCACCGGTGACGACGGCGACACCAGGCTGGGCGAGGACGACTGGCGTGAACTGGCCGGATTCGC
CTTCGCCCATCGGCCGCTGGAGGCCAGCCTGGGGGCGTTACAGCGTTTATTGTTAGCCAGCGCTTTGCCGCTGCCCGCAC
TGCGGCTGCATCTGCAACAGCAAACGACATCGGCAGGTTGCGTGGAGCTACTTGGTTTCAGCGGCCAGAAAGCCTTGCTG
CGTCGCTGGCGACAAGAGACGGGAATGGCGCTTGAACAGCTCGATGCGCAGCATTGCCTGCGCTGGCACGACTGGTCGCA
GTCATTGCAATAA

Upstream 100 bases:

>100_bases
TGATTTTCCTGGGTTTTTAGTTTGTGAATACTGACATTCCAACTTTCCGTTGGGGGAGTCAGCGGTCTGGGCACTTTTTT
AGCTCTGGGTCTGGATACTG

Downstream 100 bases:

>100_bases
ATTGAAGATGTTGCTCAATAAAACCCGATTTTCCTGAATTCTCAGCGGCGTATAGTAGCTGGCAGGAACCGGGGCATCTG
GCGCCGGGCAGAATTTGATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MLQAMQQLMQQQGIRRLLVLSGEPQWCRQQAHRLATTLPGDWPWVGENPPSGMQSLASGAVRTLLGQERLHAVYDATDGL
DVEALAALAGTLRAGSWLLLLTPPWQSWHQQPDSDSLRWSDCPQPITTPNFIHHLQQHLAADSEVTLWRQDEPLTLAPLP
VRPQWQAPNGQPTFEQQALLTQLLGAEPGVWVLTAARGRGKSTLAGMLVANTPLTCWLTGPSRAATEVAGEWAQGRAQFW
APDALLAHCREHDVSDVGWLLVDEAAAIPGPLLRQWVNHFPRILLTTTVQGYEGTGRGFLLKFCAGLPEFQPLELQQPMR
WAPGDALERVIDNALLFNELPPWQATDRPVSITGAEQRALCADPQRLVRFYALLSSAHYRTSPLDLRRLMDAPGMHFGLA
QVEDEVVGALWLVEEGGLSAELAHEVWAGRRRPRGNLVAQSLAAHGGQWWAPTLRSRRITRIAVLPAMRQQGIARRLIEQ
QRQQAQGLDYLSVSFGYTEPLWRFWQSCGFELARIGSKIEASSGCYSVMAILPLSEQGEALRHAAHKHLARDWRWLQPRI
DLQLEVTGDDGDTRLGEDDWRELAGFAFAHRPLEASLGALQRLLLASALPLPALRLHLQQQTTSAGCVELLGFSGQKALL
RRWRQETGMALEQLDAQHCLRWHDWSQSLQ

Sequences:

>Translated_670_residues
MLQAMQQLMQQQGIRRLLVLSGEPQWCRQQAHRLATTLPGDWPWVGENPPSGMQSLASGAVRTLLGQERLHAVYDATDGL
DVEALAALAGTLRAGSWLLLLTPPWQSWHQQPDSDSLRWSDCPQPITTPNFIHHLQQHLAADSEVTLWRQDEPLTLAPLP
VRPQWQAPNGQPTFEQQALLTQLLGAEPGVWVLTAARGRGKSTLAGMLVANTPLTCWLTGPSRAATEVAGEWAQGRAQFW
APDALLAHCREHDVSDVGWLLVDEAAAIPGPLLRQWVNHFPRILLTTTVQGYEGTGRGFLLKFCAGLPEFQPLELQQPMR
WAPGDALERVIDNALLFNELPPWQATDRPVSITGAEQRALCADPQRLVRFYALLSSAHYRTSPLDLRRLMDAPGMHFGLA
QVEDEVVGALWLVEEGGLSAELAHEVWAGRRRPRGNLVAQSLAAHGGQWWAPTLRSRRITRIAVLPAMRQQGIARRLIEQ
QRQQAQGLDYLSVSFGYTEPLWRFWQSCGFELARIGSKIEASSGCYSVMAILPLSEQGEALRHAAHKHLARDWRWLQPRI
DLQLEVTGDDGDTRLGEDDWRELAGFAFAHRPLEASLGALQRLLLASALPLPALRLHLQQQTTSAGCVELLGFSGQKALL
RRWRQETGMALEQLDAQHCLRWHDWSQSLQ
>Mature_670_residues
MLQAMQQLMQQQGIRRLLVLSGEPQWCRQQAHRLATTLPGDWPWVGENPPSGMQSLASGAVRTLLGQERLHAVYDATDGL
DVEALAALAGTLRAGSWLLLLTPPWQSWHQQPDSDSLRWSDCPQPITTPNFIHHLQQHLAADSEVTLWRQDEPLTLAPLP
VRPQWQAPNGQPTFEQQALLTQLLGAEPGVWVLTAARGRGKSTLAGMLVANTPLTCWLTGPSRAATEVAGEWAQGRAQFW
APDALLAHCREHDVSDVGWLLVDEAAAIPGPLLRQWVNHFPRILLTTTVQGYEGTGRGFLLKFCAGLPEFQPLELQQPMR
WAPGDALERVIDNALLFNELPPWQATDRPVSITGAEQRALCADPQRLVRFYALLSSAHYRTSPLDLRRLMDAPGMHFGLA
QVEDEVVGALWLVEEGGLSAELAHEVWAGRRRPRGNLVAQSLAAHGGQWWAPTLRSRRITRIAVLPAMRQQGIARRLIEQ
QRQQAQGLDYLSVSFGYTEPLWRFWQSCGFELARIGSKIEASSGCYSVMAILPLSEQGEALRHAAHKHLARDWRWLQPRI
DLQLEVTGDDGDTRLGEDDWRELAGFAFAHRPLEASLGALQRLLLASALPLPALRLHLQQQTTSAGCVELLGFSGQKALL
RRWRQETGMALEQLDAQHCLRWHDWSQSLQ

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788818, Length=663, Percent_Identity=53.2428355957768, Blast_Score=647, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17507621, Length=447, Percent_Identity=23.489932885906, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640662, Length=388, Percent_Identity=25.5154639175258, Blast_Score=96, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 74782; Mature: 74782

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQAMQQLMQQQGIRRLLVLSGEPQWCRQQAHRLATTLPGDWPWVGENPPSGMQSLASGA
CHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
VRTLLGQERLHAVYDATDGLDVEALAALAGTLRAGSWLLLLTPPWQSWHQQPDSDSLRWS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCCCC
DCPQPITTPNFIHHLQQHLAADSEVTLWRQDEPLTLAPLPVRPQWQAPNGQPTFEQQALL
CCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCHHHHHHH
TQLLGAEPGVWVLTAARGRGKSTLAGMLVANTPLTCWLTGPSRAATEVAGEWAQGRAQFW
HHHHCCCCCEEEEEECCCCCCHHHHHHEEECCCEEEEECCCCHHHHHHHHHHHCCCHHHC
APDALLAHCREHDVSDVGWLLVDEAAAIPGPLLRQWVNHFPRILLTTTVQGYEGTGRGFL
CCHHHHHHHHHCCCCHHHHHEECCHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHH
LKFCAGLPEFQPLELQQPMRWAPGDALERVIDNALLFNELPPWQATDRPVSITGAEQRAL
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCH
CADPQRLVRFYALLSSAHYRTSPLDLRRLMDAPGMHFGLAQVEDEVVGALWLVEEGGLSA
HCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEECCCCCH
ELAHEVWAGRRRPRGNLVAQSLAAHGGQWWAPTLRSRRITRIAVLPAMRQQGIARRLIEQ
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QRQQAQGLDYLSVSFGYTEPLWRFWQSCGFELARIGSKIEASSGCYSVMAILPLSEQGEA
HHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHCCCHHCCCCCCEEEHEEECCCCCCHH
LRHAAHKHLARDWRWLQPRIDLQLEVTGDDGDTRLGEDDWRELAGFAFAHRPLEASLGAL
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
QRLLLASALPLPALRLHLQQQTTSAGCVELLGFSGQKALLRRWRQETGMALEQLDAQHCL
HHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
RWHDWSQSLQ
HHHHHHHCCC
>Mature Secondary Structure
MLQAMQQLMQQQGIRRLLVLSGEPQWCRQQAHRLATTLPGDWPWVGENPPSGMQSLASGA
CHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
VRTLLGQERLHAVYDATDGLDVEALAALAGTLRAGSWLLLLTPPWQSWHQQPDSDSLRWS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCCCC
DCPQPITTPNFIHHLQQHLAADSEVTLWRQDEPLTLAPLPVRPQWQAPNGQPTFEQQALL
CCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCHHHHHHH
TQLLGAEPGVWVLTAARGRGKSTLAGMLVANTPLTCWLTGPSRAATEVAGEWAQGRAQFW
HHHHCCCCCEEEEEECCCCCCHHHHHHEEECCCEEEEECCCCHHHHHHHHHHHCCCHHHC
APDALLAHCREHDVSDVGWLLVDEAAAIPGPLLRQWVNHFPRILLTTTVQGYEGTGRGFL
CCHHHHHHHHHCCCCHHHHHEECCHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHH
LKFCAGLPEFQPLELQQPMRWAPGDALERVIDNALLFNELPPWQATDRPVSITGAEQRAL
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCH
CADPQRLVRFYALLSSAHYRTSPLDLRRLMDAPGMHFGLAQVEDEVVGALWLVEEGGLSA
HCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEECCCCCH
ELAHEVWAGRRRPRGNLVAQSLAAHGGQWWAPTLRSRRITRIAVLPAMRQQGIARRLIEQ
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QRQQAQGLDYLSVSFGYTEPLWRFWQSCGFELARIGSKIEASSGCYSVMAILPLSEQGEA
HHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHCCCHHCCCCCCEEEHEEECCCCCCHH
LRHAAHKHLARDWRWLQPRIDLQLEVTGDDGDTRLGEDDWRELAGFAFAHRPLEASLGAL
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
QRLLLASALPLPALRLHLQQQTTSAGCVELLGFSGQKALLRRWRQETGMALEQLDAQHCL
HHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
RWHDWSQSLQ
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA