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The map label for this gene is dppA [H]

Identifier: 157371668

GI number: 157371668

Start: 3800716

End: 3802311

Strand: Reverse

Name: dppA [H]

Synonym: Spro_3431

Alternate gene names: 157371668

Gene position: 3802311-3800716 (Counterclockwise)

Preceding gene: 157371669

Following gene: 157371666

Centisome position: 69.78

GC content: 55.14

Gene sequence:

>1596_bases
ATGAATAAAAAAGCAATAACAATGACGTTGGGACTATTGGCTCTAACGGTGATGGGCGGCGCTCGCGCCAGCACGCTGGT
TTATTGTTCCGAAAGCTCGCCGGAAGGGTTTAATCCGCAGTTGTTTACCTCCGGCCCGACGGTAGATGCCAGTTCGGCGA
CGATTTACAACCGGCTGGTGGACTTTAAAGTCGGTACCGTCGAGCTGCAACGGAGCCTGGCGGAAAGCTGGCAGGTGAGC
GAAGACGGAAAGCAATACACTTTTCATCTGCGCAAAGGGGTGAAATTCCAGAGCAATAAATACTTTACCCCCACCCGCGA
CTTCAACGCCGACGACGTTATCTTCTCCTTTATGCGGCAAAAAGACGCCAACAACCCCTATCACAAGGTCTCCAACGGCG
CTTACACCAACTTTGAGTCGATGGAGTTTGGCACGCTGATCAACAACATTGTCAAAGTGGATGACAACACCGTGCGTTTT
GAGCTTTCGCGTGCCGAAGCGCCGTTTGTGGCCGATCTCGGCATGTATTTCGCCACCATTCTCTCTGCCGAATATGCCGA
TGCGATGCTGAAGGCCGGCACGCCACAGCGGGTGGATAACGATCCTGTCGGCACCGGGCCATTCCAACTGGTGCAGTATC
AGAAGGATGCGAAGATCCTCTACAAGGCGTTCGACCAGTATTGGGAGGGTAAACCGAAGATAGACCGGCTGGTGTTCTCG
ATCACCCCGGATGCGGCGGTTCGCTTTGCCAAACTGCAAAAGAATGAATGTCAGGTGATGCCGTTCCCCAACCCGGCGGA
TCTCAAGCGCATGCGCGAGGACAAAAATATCCAGGTGATGGAGAAATCCGGGTTAAACATCGGGTTCCTGGCGTTCAATA
CCCAGAAAAAACCGCTGGATAACCTCAAGGTGCGGCAGGCGCTGGCGCTGGCGGTGAACAAGCCGGCGATCCTCGAGGCG
GTATTCCACGGCGCAGGCCAGCCGGCGAAGAACCTGTTGCCACCAACCCAGTGGGGCAGCAATGACCAGATTGAGGACTA
TCCGTACTCCCCGGAAAAAGCCAAACGGTTGTTGCAGGAGGCCGGACTGGGGCAGGGGTTTGCCATCGATCTGTGGGCGA
TGCCGGTACAGCGGCCGTACAATCCGAACGCCAAACGCATGGCGGAGATGATCCAGGCCGACTGGGCGAAAATCGGCGTG
AAGGCCAAGATTGTTACCTTCGAGTGGGGCGAATATTTGCAGCGGATAAAAAATGGAGAGCATCAGGCCGCGTTGATGGG
CTGGACCACCGCCAACGGCGATCCGGATAACTTCTTCGGCCCGCTGTTTACCTGCGTTTCGGCCAACGGCGGTTCAAACT
CGGCCAAATGGTGTTATCCGCCGTTCGATAAGCTGATCCAGCAGGCGCGTGAAGAGAACGATCACGCCAAACGGGTGGCG
ATGTATCAGCAGGCGCAGGTGATGATGCATGACCAAATGCCGGCGATGATGATTGCCCACTCAACCATTTTTGAGCCGGT
ACGCAAGGAAGTGAAAGGCTACGAGATTGACCCGTTTGGCAAGCACATCTTCAAACAGGTTTCGCTGGAGAAATAA

Upstream 100 bases:

>100_bases
GCACTCCCCGTTTTTCATGCTCAGAATTTGTGCTTTACATCCCTAACTGCATGATTTATTGGTATCCCTCGAGTCTGTTT
TCTACTCTGGGGATGGCACA

Downstream 100 bases:

>100_bases
TTAAAAAGGGGCTGCATGGCAGCCCCCGTTTCATTACCGGTTTATCCCACGATTAGAAATGGGTATTCACGCTCATATAG
TAAGTCCGGCCCGGTTCGTT

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MNKKAITMTLGLLALTVMGGARASTLVYCSESSPEGFNPQLFTSGPTVDASSATIYNRLVDFKVGTVELQRSLAESWQVS
EDGKQYTFHLRKGVKFQSNKYFTPTRDFNADDVIFSFMRQKDANNPYHKVSNGAYTNFESMEFGTLINNIVKVDDNTVRF
ELSRAEAPFVADLGMYFATILSAEYADAMLKAGTPQRVDNDPVGTGPFQLVQYQKDAKILYKAFDQYWEGKPKIDRLVFS
ITPDAAVRFAKLQKNECQVMPFPNPADLKRMREDKNIQVMEKSGLNIGFLAFNTQKKPLDNLKVRQALALAVNKPAILEA
VFHGAGQPAKNLLPPTQWGSNDQIEDYPYSPEKAKRLLQEAGLGQGFAIDLWAMPVQRPYNPNAKRMAEMIQADWAKIGV
KAKIVTFEWGEYLQRIKNGEHQAALMGWTTANGDPDNFFGPLFTCVSANGGSNSAKWCYPPFDKLIQQAREENDHAKRVA
MYQQAQVMMHDQMPAMMIAHSTIFEPVRKEVKGYEIDPFGKHIFKQVSLEK

Sequences:

>Translated_531_residues
MNKKAITMTLGLLALTVMGGARASTLVYCSESSPEGFNPQLFTSGPTVDASSATIYNRLVDFKVGTVELQRSLAESWQVS
EDGKQYTFHLRKGVKFQSNKYFTPTRDFNADDVIFSFMRQKDANNPYHKVSNGAYTNFESMEFGTLINNIVKVDDNTVRF
ELSRAEAPFVADLGMYFATILSAEYADAMLKAGTPQRVDNDPVGTGPFQLVQYQKDAKILYKAFDQYWEGKPKIDRLVFS
ITPDAAVRFAKLQKNECQVMPFPNPADLKRMREDKNIQVMEKSGLNIGFLAFNTQKKPLDNLKVRQALALAVNKPAILEA
VFHGAGQPAKNLLPPTQWGSNDQIEDYPYSPEKAKRLLQEAGLGQGFAIDLWAMPVQRPYNPNAKRMAEMIQADWAKIGV
KAKIVTFEWGEYLQRIKNGEHQAALMGWTTANGDPDNFFGPLFTCVSANGGSNSAKWCYPPFDKLIQQAREENDHAKRVA
MYQQAQVMMHDQMPAMMIAHSTIFEPVRKEVKGYEIDPFGKHIFKQVSLEK
>Mature_531_residues
MNKKAITMTLGLLALTVMGGARASTLVYCSESSPEGFNPQLFTSGPTVDASSATIYNRLVDFKVGTVELQRSLAESWQVS
EDGKQYTFHLRKGVKFQSNKYFTPTRDFNADDVIFSFMRQKDANNPYHKVSNGAYTNFESMEFGTLINNIVKVDDNTVRF
ELSRAEAPFVADLGMYFATILSAEYADAMLKAGTPQRVDNDPVGTGPFQLVQYQKDAKILYKAFDQYWEGKPKIDRLVFS
ITPDAAVRFAKLQKNECQVMPFPNPADLKRMREDKNIQVMEKSGLNIGFLAFNTQKKPLDNLKVRQALALAVNKPAILEA
VFHGAGQPAKNLLPPTQWGSNDQIEDYPYSPEKAKRLLQEAGLGQGFAIDLWAMPVQRPYNPNAKRMAEMIQADWAKIGV
KAKIVTFEWGEYLQRIKNGEHQAALMGWTTANGDPDNFFGPLFTCVSANGGSNSAKWCYPPFDKLIQQAREENDHAKRVA
MYQQAQVMMHDQMPAMMIAHSTIFEPVRKEVKGYEIDPFGKHIFKQVSLEK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=525, Percent_Identity=68.7619047619048, Blast_Score=790, Evalue=0.0,
Organism=Escherichia coli, GI1787551, Length=510, Percent_Identity=36.4705882352941, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1787052, Length=478, Percent_Identity=29.7071129707113, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1787762, Length=544, Percent_Identity=23.5294117647059, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789887, Length=512, Percent_Identity=25.1953125, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1787495, Length=510, Percent_Identity=25.2941176470588, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789397, Length=509, Percent_Identity=23.5756385068762, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081878, Length=466, Percent_Identity=23.3905579399142, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59736; Mature: 59736

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKAITMTLGLLALTVMGGARASTLVYCSESSPEGFNPQLFTSGPTVDASSATIYNRLV
CCCCEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHHHH
DFKVGTVELQRSLAESWQVSEDGKQYTFHLRKGVKFQSNKYFTPTRDFNADDVIFSFMRQ
HCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHH
KDANNPYHKVSNGAYTNFESMEFGTLINNIVKVDDNTVRFELSRAEAPFVADLGMYFATI
HCCCCCHHHCCCCCCCCCCCCHHHHHHHHHEECCCCEEEEEECCCCCCHHHHHHHHHHHH
LSAEYADAMLKAGTPQRVDNDPVGTGPFQLVQYQKDAKILYKAFDQYWEGKPKIDRLVFS
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEE
ITPDAAVRFAKLQKNECQVMPFPNPADLKRMREDKNIQVMEKSGLNIGFLAFNTQKKPLD
ECCHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCH
NLKVRQALALAVNKPAILEAVFHGAGQPAKNLLPPTQWGSNDQIEDYPYSPEKAKRLLQE
HHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AGLGQGFAIDLWAMPVQRPYNPNAKRMAEMIQADWAKIGVKAKIVTFEWGEYLQRIKNGE
CCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCC
HQAALMGWTTANGDPDNFFGPLFTCVSANGGSNSAKWCYPPFDKLIQQAREENDHAKRVA
CCEEEEEEECCCCCCCCHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHH
MYQQAQVMMHDQMPAMMIAHSTIFEPVRKEVKGYEIDPFGKHIFKQVSLEK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKKAITMTLGLLALTVMGGARASTLVYCSESSPEGFNPQLFTSGPTVDASSATIYNRLV
CCCCEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHHHH
DFKVGTVELQRSLAESWQVSEDGKQYTFHLRKGVKFQSNKYFTPTRDFNADDVIFSFMRQ
HCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHH
KDANNPYHKVSNGAYTNFESMEFGTLINNIVKVDDNTVRFELSRAEAPFVADLGMYFATI
HCCCCCHHHCCCCCCCCCCCCHHHHHHHHHEECCCCEEEEEECCCCCCHHHHHHHHHHHH
LSAEYADAMLKAGTPQRVDNDPVGTGPFQLVQYQKDAKILYKAFDQYWEGKPKIDRLVFS
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEE
ITPDAAVRFAKLQKNECQVMPFPNPADLKRMREDKNIQVMEKSGLNIGFLAFNTQKKPLD
ECCHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCH
NLKVRQALALAVNKPAILEAVFHGAGQPAKNLLPPTQWGSNDQIEDYPYSPEKAKRLLQE
HHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AGLGQGFAIDLWAMPVQRPYNPNAKRMAEMIQADWAKIGVKAKIVTFEWGEYLQRIKNGE
CCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCC
HQAALMGWTTANGDPDNFFGPLFTCVSANGGSNSAKWCYPPFDKLIQQAREENDHAKRVA
CCEEEEEEECCCCCCCCHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHH
MYQQAQVMMHDQMPAMMIAHSTIFEPVRKEVKGYEIDPFGKHIFKQVSLEK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]