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The map label for this gene is fes [H]

Identifier: 157371666

GI number: 157371666

Start: 3796665

End: 3798035

Strand: Reverse

Name: fes [H]

Synonym: Spro_3429

Alternate gene names: 157371666

Gene position: 3798035-3796665 (Counterclockwise)

Preceding gene: 157371668

Following gene: 157371665

Centisome position: 69.7

GC content: 60.32

Gene sequence:

>1371_bases
TTGAAAACAAAATCCGAGTCAGAAAGCAGCAGATTATTATCGAGCAAGCACGCAGGGCGCCATGGATGGTGGCTGACTAT
CGCCAAACGCGGCACGCCGCTGGTGGAACTGCAGGGGGATGGGCGAGGGAAGGTCACATTTTTATGGCGCGATCCGCAGG
GATGTGAACTCACTTCAGCCTATCAACGCGTCTGGATCCACATCAATTGCCTGACCGACCACCACCAGTCGTCGCCGCCG
CAGAGCCTGCAACGGCTGGAAGGGACCGACGTCTGGTACTGGCAAACCGAACTGAGCGCCGACTGGCGTGGCAGCTACTG
CTTTATCCCCTGTATGGACGACCGACCGCTGGAACACAGTGGCGACGATGCACACGCCAATATGCATTCGATTCGTCACT
GGTGGCATCAGGTGTTTGCCGGTGCCACTCAGGATCTGCTGAATCCCCATCGTTCATGGACCGGTGTTGGCGGCAACGTG
CTGTCCGGGCTGCATATGCCGGAAGCCCCAGCACAAGCGGCCTGGCAGGATTTCGATCGGTACGCCGTGGCCAGTGGACG
CTGTACGCCAGCGCCACCGGCCAGACTACAGCGTCACAGTTGGCACAGCGAGCGGTTGGGTAATACCCGCGACGTCTGGG
TTTACACCACCGGCGACAGCAACCCGGCGCAGCGACCGCTGGCGGTATTGCTGGACGGCCAGTTCTGGTCGAGCAACATG
CCGGTCTGGGATCCGCTGATGCAGTTGACCCGTGAAGGCCAATTGCCGGAAGCGGTTTATCTGCTGATCGACATTATCAG
TCTCAAGCACCGCAGCCAGGAGCTGGCCTGCAATGAAGATTTCTGGCTGGCGGTGCAAGAAGAACTGCTGCCGCAGGTGG
CCGAATGGGCACCTCACAGCCGTGATCCTGCCACGACGTTGGTATGCGGCCAGAGTTTTGGCGGCCTGTCGTCGCTGTAT
GCCGGGTTGCACTGGCCACAGTGCTTCGGTGGAGTGATCAGCCAGTCCGGTTCATTCTGGTGGCCGCGCCGCGATATGTA
TCAGCGTGAAACAATACCGGCCGATGCCGGCTGGCTGCTGCATCAGGTAGAGCAGGGCGTCGGTCAGGGTAAATTGAAGG
TATTTATGGAAGCCGGCGTGCACGAAAAAGTGGCGCACCGGGTGAATGACCGAATGGCAGAGTTGCTGCGTGACGCCGGG
CATCGGGTGCAATACCGGACGGTGGCGGGCGGCCATGACTATCTGTGCTGGCGTGGCGGCCTGATCGACGGGCTGCAGGC
GCTGTGGTCGGATAGCCTTCCTGCCTCTGCGGCCAAACTCACCTTCACCGTCCAGGGAGTCCGTGATGGAAACTCAGAAC
CCGTTCGATGA

Upstream 100 bases:

>100_bases
ATTATCAATAGTATTCGGTTTACCGTTTTCTTGGGCAGCGCCTCGTGCCGCGAATTTACCGGCTTTCCTGAAGCTGCCAG
CTAAATAGTGAATAGGCGTT

Downstream 100 bases:

>100_bases
CGAACAACAAATTTGCCTGATTGTGTGCAATGACCAACTGCAGTACAGCCTGTGGCCCGAATTTAGCGCAGTACCGGCGG
GGTGGACGCCGGTATTCGGC

Product: enterobactin/ferric enterobactin esterase

Products: Fe [C]

Alternate protein names: Ferric enterobactin esterase [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MKTKSESESSRLLSSKHAGRHGWWLTIAKRGTPLVELQGDGRGKVTFLWRDPQGCELTSAYQRVWIHINCLTDHHQSSPP
QSLQRLEGTDVWYWQTELSADWRGSYCFIPCMDDRPLEHSGDDAHANMHSIRHWWHQVFAGATQDLLNPHRSWTGVGGNV
LSGLHMPEAPAQAAWQDFDRYAVASGRCTPAPPARLQRHSWHSERLGNTRDVWVYTTGDSNPAQRPLAVLLDGQFWSSNM
PVWDPLMQLTREGQLPEAVYLLIDIISLKHRSQELACNEDFWLAVQEELLPQVAEWAPHSRDPATTLVCGQSFGGLSSLY
AGLHWPQCFGGVISQSGSFWWPRRDMYQRETIPADAGWLLHQVEQGVGQGKLKVFMEAGVHEKVAHRVNDRMAELLRDAG
HRVQYRTVAGGHDYLCWRGGLIDGLQALWSDSLPASAAKLTFTVQGVRDGNSEPVR

Sequences:

>Translated_456_residues
MKTKSESESSRLLSSKHAGRHGWWLTIAKRGTPLVELQGDGRGKVTFLWRDPQGCELTSAYQRVWIHINCLTDHHQSSPP
QSLQRLEGTDVWYWQTELSADWRGSYCFIPCMDDRPLEHSGDDAHANMHSIRHWWHQVFAGATQDLLNPHRSWTGVGGNV
LSGLHMPEAPAQAAWQDFDRYAVASGRCTPAPPARLQRHSWHSERLGNTRDVWVYTTGDSNPAQRPLAVLLDGQFWSSNM
PVWDPLMQLTREGQLPEAVYLLIDIISLKHRSQELACNEDFWLAVQEELLPQVAEWAPHSRDPATTLVCGQSFGGLSSLY
AGLHWPQCFGGVISQSGSFWWPRRDMYQRETIPADAGWLLHQVEQGVGQGKLKVFMEAGVHEKVAHRVNDRMAELLRDAG
HRVQYRTVAGGHDYLCWRGGLIDGLQALWSDSLPASAAKLTFTVQGVRDGNSEPVR
>Mature_456_residues
MKTKSESESSRLLSSKHAGRHGWWLTIAKRGTPLVELQGDGRGKVTFLWRDPQGCELTSAYQRVWIHINCLTDHHQSSPP
QSLQRLEGTDVWYWQTELSADWRGSYCFIPCMDDRPLEHSGDDAHANMHSIRHWWHQVFAGATQDLLNPHRSWTGVGGNV
LSGLHMPEAPAQAAWQDFDRYAVASGRCTPAPPARLQRHSWHSERLGNTRDVWVYTTGDSNPAQRPLAVLLDGQFWSSNM
PVWDPLMQLTREGQLPEAVYLLIDIISLKHRSQELACNEDFWLAVQEELLPQVAEWAPHSRDPATTLVCGQSFGGLSSLY
AGLHWPQCFGGVISQSGSFWWPRRDMYQRETIPADAGWLLHQVEQGVGQGKLKVFMEAGVHEKVAHRVNDRMAELLRDAG
HRVQYRTVAGGHDYLCWRGGLIDGLQALWSDSLPASAAKLTFTVQGVRDGNSEPVR

Specific function: Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use [H]

COG id: COG2382

COG function: function code P; Enterochelin esterase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fes family [H]

Homologues:

Organism=Escherichia coli, GI1786799, Length=387, Percent_Identity=48.578811369509, Blast_Score=349, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021764
- InterPro:   IPR000801
- InterPro:   IPR014756 [H]

Pfam domain/function: PF11806 DUF3327; PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 51428; Mature: 51428

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKSESESSRLLSSKHAGRHGWWLTIAKRGTPLVELQGDGRGKVTFLWRDPQGCELTSA
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCHHHH
YQRVWIHINCLTDHHQSSPPQSLQRLEGTDVWYWQTELSADWRGSYCFIPCMDDRPLEHS
CEEEEEEEEEEECCCCCCCHHHHHHCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCC
GDDAHANMHSIRHWWHQVFAGATQDLLNPHRSWTGVGGNVLSGLHMPEAPAQAAWQDFDR
CCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
YAVASGRCTPAPPARLQRHSWHSERLGNTRDVWVYTTGDSNPAQRPLAVLLDGQFWSSNM
HHHCCCCCCCCCHHHHHHCCCHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCC
PVWDPLMQLTREGQLPEAVYLLIDIISLKHRSQELACNEDFWLAVQEELLPQVAEWAPHS
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEHHHHHHHHHHHCCCC
RDPATTLVCGQSFGGLSSLYAGLHWPQCFGGVISQSGSFWWPRRDMYQRETIPADAGWLL
CCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHH
HQVEQGVGQGKLKVFMEAGVHEKVAHRVNDRMAELLRDAGHRVQYRTVAGGHDYLCWRGG
HHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECC
LIDGLQALWSDSLPASAAKLTFTVQGVRDGNSEPVR
HHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MKTKSESESSRLLSSKHAGRHGWWLTIAKRGTPLVELQGDGRGKVTFLWRDPQGCELTSA
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCHHHH
YQRVWIHINCLTDHHQSSPPQSLQRLEGTDVWYWQTELSADWRGSYCFIPCMDDRPLEHS
CEEEEEEEEEEECCCCCCCHHHHHHCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCC
GDDAHANMHSIRHWWHQVFAGATQDLLNPHRSWTGVGGNVLSGLHMPEAPAQAAWQDFDR
CCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
YAVASGRCTPAPPARLQRHSWHSERLGNTRDVWVYTTGDSNPAQRPLAVLLDGQFWSSNM
HHHCCCCCCCCCHHHHHHCCCHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCC
PVWDPLMQLTREGQLPEAVYLLIDIISLKHRSQELACNEDFWLAVQEELLPQVAEWAPHS
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEHHHHHHHHHHHCCCC
RDPATTLVCGQSFGGLSSLYAGLHWPQCFGGVISQSGSFWWPRRDMYQRETIPADAGWLL
CCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHH
HQVEQGVGQGKLKVFMEAGVHEKVAHRVNDRMAELLRDAGHRVQYRTVAGGHDYLCWRGG
HHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECC
LIDGLQALWSDSLPASAAKLTFTVQGVRDGNSEPVR
HHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrienterobactin [C]

Specific reaction: ferrienterobactin = Fe [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA