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The map label for this gene is mntH [H]

Identifier: 157371652

GI number: 157371652

Start: 3776547

End: 3777779

Strand: Reverse

Name: mntH [H]

Synonym: Spro_3415

Alternate gene names: 157371652

Gene position: 3777779-3776547 (Counterclockwise)

Preceding gene: 157371654

Following gene: 157371649

Centisome position: 69.33

GC content: 55.15

Gene sequence:

>1233_bases
ATGCTGAACAGTCGCGTGGTTGAGACCACCCCGCGCTCATCCAGGAAGATCAAACTTTCCCTGATGGGCCCCGCATTTAT
CGCGGCTATCGGCTACATTGACCCCGGTAATTTCGCCACCAATATTCAGTCCGGTGCCTCTTTTGGTTATACCCTGCTGT
GGGTGGTGGTGTGGGCCAATGTGATGGCGATGTTGATCCAACTGTTGTCTGCCAAACTGGGCATTGCCACGGGTAAAAAC
CTGGCGGAGCATATTCGCGATCGTTTCCCGCGTCCGGCGGTGTGGGCTTATTGGGTTCAGGCAGAAATTATTGCGATGGC
CACAGATCTGGCCGAATTTATCGGCGCGGCTATAGGTTTCAAACTGCTGTTGGGCGTGACTTTGCTGGAGGGAGCGATCC
TGACCGGCATCGCGACTTTCCTGATCCTGATGTTGCAACAACGTGGGCAAAAATCTTTGGAATGGGTGATTGGCAGCCTG
CTGCTGTTTGTCGCTTTGGCTTATATGGTGGAACTGGTGTTTTCCCAACCGCAGTTAGGCCCGCTGTTAACAGGCATGGC
GCTGCCGGATTTGCCGAACGGTGATGCGGTGTTTCTGGCCGCCGGGGTGCTTGGTGCCACCATTATGCCGCACGTGATTT
ATCTGCATTCGTCGTTAACTCAGGCAGCAGGGGAAAACTCAAAGGCCGACAGGTATGCTGCCACCAAGGTCGATGTGGCC
ATTGCCATGACCATTGCCGGGTTTGTTAACCTGGCGATGATGGCTACCGCCGCCGCGGCCTTTCACTTTAATGGTCACAG
CGGTATTACCGATCTTGACCAGGCCTATCTAACGCTGCAGCCCTTGTTGGGGCAGGCGGCGGCCACGATCTTCGGGCTGA
GCCTGGTAGCCGCTGGGTTATCTTCTACCGTGGTGGGCACGCTGGCGGGGCAGGTGGTGATGCAGGGATTTGTGCGTTTT
TACATTCCGCTGTGGGTGCGTCGTGTGGTCACCATGCTGCCATCGTTTATCGTCATTATGTTGGGGATGGACGCCACACG
CATTTTGGTACTGAGCCAGGTATTGCTGAGTTTCGGTATTGCACTGGCATTGGTGCCGTTGCTGTCGTTCACCGGGAATC
GTGAGTTGATGGGTGAGATGGTGAATAGCCGCACCATACAGACGATAGGTAAGTTGATCGTGGTGGTAGTGGTGGGGTTG
AACGGTTATCTGCTGGTCAGTAGCCTGCTGTGA

Upstream 100 bases:

>100_bases
ATCTATTGCAGAGATAAGTATTACCGCCATAAATGCACTTGATAATTATTATCATTTACATAAGATAACCCCAGGCTTAT
TAGAAGTAAGGGTTCAGAAC

Downstream 100 bases:

>100_bases
GCGCCTATTAAATGAAAGGCCGGCAGTGCCTAATGCCGGTCAGCTAAGCAAAATTCTGAATAATAATGTACGACTTTGCT
AAAGCGATAGTCCCCCTCTC

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLNSRVVETTPRSSRKIKLSLMGPAFIAAIGYIDPGNFATNIQSGASFGYTLLWVVVWANVMAMLIQLLSAKLGIATGKN
LAEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGFKLLLGVTLLEGAILTGIATFLILMLQQRGQKSLEWVIGSL
LLFVALAYMVELVFSQPQLGPLLTGMALPDLPNGDAVFLAAGVLGATIMPHVIYLHSSLTQAAGENSKADRYAATKVDVA
IAMTIAGFVNLAMMATAAAAFHFNGHSGITDLDQAYLTLQPLLGQAAATIFGLSLVAAGLSSTVVGTLAGQVVMQGFVRF
YIPLWVRRVVTMLPSFIVIMLGMDATRILVLSQVLLSFGIALALVPLLSFTGNRELMGEMVNSRTIQTIGKLIVVVVVGL
NGYLLVSSLL

Sequences:

>Translated_410_residues
MLNSRVVETTPRSSRKIKLSLMGPAFIAAIGYIDPGNFATNIQSGASFGYTLLWVVVWANVMAMLIQLLSAKLGIATGKN
LAEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGFKLLLGVTLLEGAILTGIATFLILMLQQRGQKSLEWVIGSL
LLFVALAYMVELVFSQPQLGPLLTGMALPDLPNGDAVFLAAGVLGATIMPHVIYLHSSLTQAAGENSKADRYAATKVDVA
IAMTIAGFVNLAMMATAAAAFHFNGHSGITDLDQAYLTLQPLLGQAAATIFGLSLVAAGLSSTVVGTLAGQVVMQGFVRF
YIPLWVRRVVTMLPSFIVIMLGMDATRILVLSQVLLSFGIALALVPLLSFTGNRELMGEMVNSRTIQTIGKLIVVVVVGL
NGYLLVSSLL
>Mature_410_residues
MLNSRVVETTPRSSRKIKLSLMGPAFIAAIGYIDPGNFATNIQSGASFGYTLLWVVVWANVMAMLIQLLSAKLGIATGKN
LAEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGFKLLLGVTLLEGAILTGIATFLILMLQQRGQKSLEWVIGSL
LLFVALAYMVELVFSQPQLGPLLTGMALPDLPNGDAVFLAAGVLGATIMPHVIYLHSSLTQAAGENSKADRYAATKVDVA
IAMTIAGFVNLAMMATAAAAFHFNGHSGITDLDQAYLTLQPLLGQAAATIFGLSLVAAGLSSTVVGTLAGQVVMQGFVRF
YIPLWVRRVVTMLPSFIVIMLGMDATRILVLSQVLLSFGIALALVPLLSFTGNRELMGEMVNSRTIQTIGKLIVVVVVGL
NGYLLVSSLL

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=445, Percent_Identity=34.1573033707865, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI295293167, Length=438, Percent_Identity=31.0502283105023, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI295293171, Length=438, Percent_Identity=31.0502283105023, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI295293169, Length=438, Percent_Identity=31.0502283105023, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI295293178, Length=438, Percent_Identity=31.0502283105023, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI295293175, Length=438, Percent_Identity=31.0502283105023, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI295293173, Length=438, Percent_Identity=31.0502283105023, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI10835169, Length=438, Percent_Identity=31.0502283105023, Blast_Score=165, Evalue=9e-41,
Organism=Escherichia coli, GI1788736, Length=410, Percent_Identity=77.8048780487805, Blast_Score=618, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI193210616, Length=436, Percent_Identity=29.8165137614679, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17569473, Length=397, Percent_Identity=30.7304785894207, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71999499, Length=452, Percent_Identity=28.9823008849558, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71993856, Length=212, Percent_Identity=37.7358490566038, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323062, Length=391, Percent_Identity=32.9923273657289, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6324450, Length=415, Percent_Identity=28.6746987951807, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6321841, Length=412, Percent_Identity=29.126213592233, Blast_Score=152, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24648607, Length=437, Percent_Identity=32.4942791762014, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI281362176, Length=437, Percent_Identity=32.4942791762014, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24648609, Length=437, Percent_Identity=32.4942791762014, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI45553443, Length=413, Percent_Identity=32.6876513317191, Blast_Score=211, Evalue=7e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 43696; Mature: 43696

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSRVVETTPRSSRKIKLSLMGPAFIAAIGYIDPGNFATNIQSGASFGYTLLWVVVWAN
CCCCCEECCCCCCCCEEEEEEECHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHHHHHH
VMAMLIQLLSAKLGIATGKNLAEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLLGVTLLEGAILTGIATFLILMLQQRGQKSLEWVIGSLLLFVALAYMVELVFSQPQLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLLTGMALPDLPNGDAVFLAAGVLGATIMPHVIYLHSSLTQAAGENSKADRYAATKVDVA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IAMTIAGFVNLAMMATAAAAFHFNGHSGITDLDQAYLTLQPLLGQAAATIFGLSLVAAGL
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSTVVGTLAGQVVMQGFVRFYIPLWVRRVVTMLPSFIVIMLGMDATRILVLSQVLLSFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALALVPLLSFTGNRELMGEMVNSRTIQTIGKLIVVVVVGLNGYLLVSSLL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MLNSRVVETTPRSSRKIKLSLMGPAFIAAIGYIDPGNFATNIQSGASFGYTLLWVVVWAN
CCCCCEECCCCCCCCEEEEEEECHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHHHHHH
VMAMLIQLLSAKLGIATGKNLAEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLLGVTLLEGAILTGIATFLILMLQQRGQKSLEWVIGSLLLFVALAYMVELVFSQPQLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLLTGMALPDLPNGDAVFLAAGVLGATIMPHVIYLHSSLTQAAGENSKADRYAATKVDVA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IAMTIAGFVNLAMMATAAAAFHFNGHSGITDLDQAYLTLQPLLGQAAATIFGLSLVAAGL
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSTVVGTLAGQVVMQGFVRFYIPLWVRRVVTMLPSFIVIMLGMDATRILVLSQVLLSFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALALVPLLSFTGNRELMGEMVNSRTIQTIGKLIVVVVVGLNGYLLVSSLL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA