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The map label for this gene is yyaJ [H]

Identifier: 157371430

GI number: 157371430

Start: 3515876

End: 3517294

Strand: Reverse

Name: yyaJ [H]

Synonym: Spro_3193

Alternate gene names: 157371430

Gene position: 3517294-3515876 (Counterclockwise)

Preceding gene: 157371431

Following gene: 157371428

Centisome position: 64.55

GC content: 55.32

Gene sequence:

>1419_bases
GTGAGTGATGTTTTGGTTGCAGGAAGCGATGCGGTGGCCCAGTCACCGATCCATGAACAGGATTTGTCAGCAAGAATTGA
TGCGTTGCCGACCTCGGCCGGCCTGTGGAAGTTTATCGCTTTGCTGGCGTTGGGCGGTTTTTTTGAGCTTTATGACCTGT
TCCAGACCGGCTATATCAGCACCGGTTTAATTGCCGAGGGGATATTCCATACCGGCGCGCAAGGCGTGTTCGGCGTCTCC
GACCAGGCGGCTTTTGCCTCCGCCACCTTCCTTGGCCTGTTTATCGGCGCCAGCCTGCTCAGCCCCTACGCCGACCGCTT
TGGCCGCCGCACCACCTTTATGTTTGCGCTGGCCTGGTACGGCGTGTTTTCGCTGTGCCTGGCCTTTCAGCATCAGGCAG
AGTGGGTGATCTTCCTGCGTTTTTTGGTGGGAGTCGGATTGGGGATTGAACTGGTCACCATAGATACCTATCTGACCGAG
TGGGTGCCTGCGCATCTGCGTACCCGGGCCTTTGCCTTTTCGTTTTTCATTCAATTTCTGTCGGTGCCAACGGTCGCGTT
GATGTCGTGGTGGCTGGTACCACAGACCATTTTGGGTCTGAGCGGCTGGCGTTATGTGGTGATCGCCGGTGCCGTGGCTT
CGCTGGTGATTTGGCTGGTGCGTAAAGGCTTGCCGGAGTCCCCGCGTTGGCTGGCGCAGCAGCGACGTTACCCGGAGGTC
AGGCAGGTAATGCTAGCGATGGAGCGTCGTTGCGGTGTTACCCAGGTGACGGAATTCCCGTTGCGTGATGCCGAATCAGC
AAGTGAAACGCCCGCGCAGGGAAGCTTTAAAGATATCTGGTCGCCGCGTTATCGGGGGCGAACCCTGATGCTGGTGGTGA
TGAATTTCTTCCAGGCGATTGGTTTCTTCGGTTTTGGCAACTGGCTGCCGGCCTTACTGGCCGGAAAGGGCGCTTCAATC
ACCCACAGTCTGCTGTACGCCTTCTTTATTACCCTGGCTTACCCGCTGGGATCATTGCTGTGCAGTCGCTATGCCGACAA
GATGGAAAACAAATGGCAGATTGTTCTTTCCTGCCTGGTGACGGTGATTTTCGGCTCACTGTTTGCCATGCAGAATAATC
CCCTGTGGCTGATTCTGTGCGGGTTCTTCATTACCTGGTCCAATGCCTGGCTGACCTACAGTTACCACTCCTACCAGTCA
GAAGTGTTCCCGACTTATATCCGTGCCCGTGCGGTCGGATTCTGTTATTCGTTCAGCCGATTGTCGACGGTATTCAGCAG
CCTGATTATTGGCATGATCCTGCAATACGGCGGTTCGGTAGGGGTGATTGCGTTTATCGTTGCCAGCATGCTGATTGTGA
TGGTGGTGATCGGGGTGTTTGGTCCAAAAACTCGCGGTATCGATCTGGAAAATATCTGA

Upstream 100 bases:

>100_bases
TATGCTTAATTACCTTTCATAGCCTGCTAATTAAATATTTAACTCCGACGCCGAGCCTATAGCATAGAAAAATAATAATT
ATGTTATGGCGAGGTTAATG

Downstream 100 bases:

>100_bases
CCGAGCCACCCGGCGTTGCGCATTGAGACAACGCCGGGATCTTCATGCTGTTATTACTTAGGCCAGATCAAAACGATCGA
GGTTCATCACCTTATTCCAG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSDVLVAGSDAVAQSPIHEQDLSARIDALPTSAGLWKFIALLALGGFFELYDLFQTGYISTGLIAEGIFHTGAQGVFGVS
DQAAFASATFLGLFIGASLLSPYADRFGRRTTFMFALAWYGVFSLCLAFQHQAEWVIFLRFLVGVGLGIELVTIDTYLTE
WVPAHLRTRAFAFSFFIQFLSVPTVALMSWWLVPQTILGLSGWRYVVIAGAVASLVIWLVRKGLPESPRWLAQQRRYPEV
RQVMLAMERRCGVTQVTEFPLRDAESASETPAQGSFKDIWSPRYRGRTLMLVVMNFFQAIGFFGFGNWLPALLAGKGASI
THSLLYAFFITLAYPLGSLLCSRYADKMENKWQIVLSCLVTVIFGSLFAMQNNPLWLILCGFFITWSNAWLTYSYHSYQS
EVFPTYIRARAVGFCYSFSRLSTVFSSLIIGMILQYGGSVGVIAFIVASMLIVMVVIGVFGPKTRGIDLENI

Sequences:

>Translated_472_residues
MSDVLVAGSDAVAQSPIHEQDLSARIDALPTSAGLWKFIALLALGGFFELYDLFQTGYISTGLIAEGIFHTGAQGVFGVS
DQAAFASATFLGLFIGASLLSPYADRFGRRTTFMFALAWYGVFSLCLAFQHQAEWVIFLRFLVGVGLGIELVTIDTYLTE
WVPAHLRTRAFAFSFFIQFLSVPTVALMSWWLVPQTILGLSGWRYVVIAGAVASLVIWLVRKGLPESPRWLAQQRRYPEV
RQVMLAMERRCGVTQVTEFPLRDAESASETPAQGSFKDIWSPRYRGRTLMLVVMNFFQAIGFFGFGNWLPALLAGKGASI
THSLLYAFFITLAYPLGSLLCSRYADKMENKWQIVLSCLVTVIFGSLFAMQNNPLWLILCGFFITWSNAWLTYSYHSYQS
EVFPTYIRARAVGFCYSFSRLSTVFSSLIIGMILQYGGSVGVIAFIVASMLIVMVVIGVFGPKTRGIDLENI
>Mature_471_residues
SDVLVAGSDAVAQSPIHEQDLSARIDALPTSAGLWKFIALLALGGFFELYDLFQTGYISTGLIAEGIFHTGAQGVFGVSD
QAAFASATFLGLFIGASLLSPYADRFGRRTTFMFALAWYGVFSLCLAFQHQAEWVIFLRFLVGVGLGIELVTIDTYLTEW
VPAHLRTRAFAFSFFIQFLSVPTVALMSWWLVPQTILGLSGWRYVVIAGAVASLVIWLVRKGLPESPRWLAQQRRYPEVR
QVMLAMERRCGVTQVTEFPLRDAESASETPAQGSFKDIWSPRYRGRTLMLVVMNFFQAIGFFGFGNWLPALLAGKGASIT
HSLLYAFFITLAYPLGSLLCSRYADKMENKWQIVLSCLVTVIFGSLFAMQNNPLWLILCGFFITWSNAWLTYSYHSYQSE
VFPTYIRARAVGFCYSFSRLSTVFSSLIIGMILQYGGSVGVIAFIVASMLIVMVVIGVFGPKTRGIDLENI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI166064021, Length=384, Percent_Identity=24.21875, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI166197673, Length=362, Percent_Identity=25.9668508287293, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4506999, Length=399, Percent_Identity=22.8070175438596, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI24308167, Length=418, Percent_Identity=23.444976076555, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI216548223, Length=271, Percent_Identity=24.3542435424354, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI203098995, Length=215, Percent_Identity=29.3023255813954, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI7662270, Length=357, Percent_Identity=21.5686274509804, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788074, Length=401, Percent_Identity=27.930174563591, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788068, Length=463, Percent_Identity=24.1900647948164, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1786229, Length=403, Percent_Identity=25.8064516129032, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87082159, Length=386, Percent_Identity=26.9430051813472, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87082404, Length=395, Percent_Identity=23.0379746835443, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320595, Length=145, Percent_Identity=26.2068965517241, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52492; Mature: 52361

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVLVAGSDAVAQSPIHEQDLSARIDALPTSAGLWKFIALLALGGFFELYDLFQTGYIS
CCCCEECCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TGLIAEGIFHTGAQGVFGVSDQAAFASATFLGLFIGASLLSPYADRFGRRTTFMFALAWY
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVFSLCLAFQHQAEWVIFLRFLVGVGLGIELVTIDTYLTEWVPAHLRTRAFAFSFFIQFL
HHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVPTVALMSWWLVPQTILGLSGWRYVVIAGAVASLVIWLVRKGLPESPRWLAQQRRYPEV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHH
RQVMLAMERRCGVTQVTEFPLRDAESASETPAQGSFKDIWSPRYRGRTLMLVVMNFFQAI
HHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHH
GFFGFGNWLPALLAGKGASITHSLLYAFFITLAYPLGSLLCSRYADKMENKWQIVLSCLV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
TVIFGSLFAMQNNPLWLILCGFFITWSNAWLTYSYHSYQSEVFPTYIRARAVGFCYSFSR
HHHHHHHHHHCCCCEEEEHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LSTVFSSLIIGMILQYGGSVGVIAFIVASMLIVMVVIGVFGPKTRGIDLENI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SDVLVAGSDAVAQSPIHEQDLSARIDALPTSAGLWKFIALLALGGFFELYDLFQTGYIS
CCCEECCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH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HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]