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The map label for this gene is citC [H]

Identifier: 157371410

GI number: 157371410

Start: 3489024

End: 3490097

Strand: Reverse

Name: citC [H]

Synonym: Spro_3171

Alternate gene names: 157371410

Gene position: 3490097-3489024 (Counterclockwise)

Preceding gene: 157371416

Following gene: 157371409

Centisome position: 64.05

GC content: 54.66

Gene sequence:

>1074_bases
ATGTTGGGCGATGCCATATTTGACCGAGTGAAAAGATCAGATCATAAAAATATTACGCAGATTAATGCCTTCCTGCGGAG
TAACGATCTGAATATTGATACGACGGTTGAAATATTTATTACCGTTACGCAAAACGATAAGTTGGTCGCCTGCGGCGGCA
TAGCAGACAATATTATCAAGTGCGTCGCTATCAGCCCACAAATGCGTGGCGAAGGCTTGGCACTGCGGCTGGCGACCGAA
CTGGTGAATCTGGCGTATGAACGCCACCACACCCAGCTATTTATCTATACCAAAATCCAAAATGAACCGCTGTTCCGCCA
GTGTGGTTTTTATCCGATAGCCCAGGTACCGGGCATCGTGGTGCTGATGGAAAACAGCCCGTGTCGCCTGAAGCGCTATG
CCGCCCAACTGGCGGGTCAGCGGCAGCCGGGCAAGCGCATTGGCAGCATTGTGATGAATGCCAACCCCTTTACCCGTGGT
CACCAATATCTGGTGCGCCAGGCGGCCGAAAAGTGCGACTGGCTGCACCTGTTTTTGGTCAAGGAAAACACCTCGCGCTT
CAGCTATGAAGACCGGCGGCGACTGGTGCTGGCAGGCACGGCAGACATTGCCAACCTGACAGTGCATGAAGGCTCGCAAT
ACGTCATTTCCCGCGCCACTTTCCCTTGTTACTTCATTAAAGATCAGGGCATTGCCGACGACTGCTACACCGAGATCGAT
CTGAAGATCTTTCGTCAGTATCTGGCACCCGCGCTGGGTATCACCCACCGTTTTGTCGGCAATGAGCCGTTCTGCGCGGT
CACCGCGAAGTACAACCGCGATATGCGTTATTGGCTGGAAACCCCGGCGTTATCCAGCCCGCCAATCGCGCTGGTAGAAA
TTGAGCGTTTGCAATATCAGGGCACGGCAATCTCCGCCTCCTGGGTGCGCAAACTGTTGGCCGCGGGTGATTTTCACGCC
GCCGCGCCGCTGGTGCCACCGGACACCCTGTATTACCTGCAAGATTTGCAAACGCAGCGCCGGGCCAAACCGGCGGCCAC
CCCCTTTGAATCCGCACAATCAGGTGAAAGATGA

Upstream 100 bases:

>100_bases
ATATTTATGGTTTTTAAGGTTTTAATTCCCCGTCGGAATGTTAATTGATGTTCGTTTTCTGTTTTATTTGTTATTTATTA
GTTAACCCAGAGAGTGTGAT

Downstream 100 bases:

>100_bases
AAATTATCCGAGAAGCAATGGCCGGCACGCTGGAATCCAGCGATGTCATGGTGCGCATCGCCCCCGCCGAGGGGCCGGAA
CACGACCTGCTGATCGCCAG

Product: citrate lyase ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLGDAIFDRVKRSDHKNITQINAFLRSNDLNIDTTVEIFITVTQNDKLVACGGIADNIIKCVAISPQMRGEGLALRLATE
LVNLAYERHHTQLFIYTKIQNEPLFRQCGFYPIAQVPGIVVLMENSPCRLKRYAAQLAGQRQPGKRIGSIVMNANPFTRG
HQYLVRQAAEKCDWLHLFLVKENTSRFSYEDRRRLVLAGTADIANLTVHEGSQYVISRATFPCYFIKDQGIADDCYTEID
LKIFRQYLAPALGITHRFVGNEPFCAVTAKYNRDMRYWLETPALSSPPIALVEIERLQYQGTAISASWVRKLLAAGDFHA
AAPLVPPDTLYYLQDLQTQRRAKPAATPFESAQSGER

Sequences:

>Translated_357_residues
MLGDAIFDRVKRSDHKNITQINAFLRSNDLNIDTTVEIFITVTQNDKLVACGGIADNIIKCVAISPQMRGEGLALRLATE
LVNLAYERHHTQLFIYTKIQNEPLFRQCGFYPIAQVPGIVVLMENSPCRLKRYAAQLAGQRQPGKRIGSIVMNANPFTRG
HQYLVRQAAEKCDWLHLFLVKENTSRFSYEDRRRLVLAGTADIANLTVHEGSQYVISRATFPCYFIKDQGIADDCYTEID
LKIFRQYLAPALGITHRFVGNEPFCAVTAKYNRDMRYWLETPALSSPPIALVEIERLQYQGTAISASWVRKLLAAGDFHA
AAPLVPPDTLYYLQDLQTQRRAKPAATPFESAQSGER
>Mature_357_residues
MLGDAIFDRVKRSDHKNITQINAFLRSNDLNIDTTVEIFITVTQNDKLVACGGIADNIIKCVAISPQMRGEGLALRLATE
LVNLAYERHHTQLFIYTKIQNEPLFRQCGFYPIAQVPGIVVLMENSPCRLKRYAAQLAGQRQPGKRIGSIVMNANPFTRG
HQYLVRQAAEKCDWLHLFLVKENTSRFSYEDRRRLVLAGTADIANLTVHEGSQYVISRATFPCYFIKDQGIADDCYTEID
LKIFRQYLAPALGITHRFVGNEPFCAVTAKYNRDMRYWLETPALSSPPIALVEIERLQYQGTAISASWVRKLLAAGDFHA
AAPLVPPDTLYYLQDLQTQRRAKPAATPFESAQSGER

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=346, Percent_Identity=69.6531791907514, Blast_Score=511, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 40302; Mature: 40302

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGDAIFDRVKRSDHKNITQINAFLRSNDLNIDTTVEIFITVTQNDKLVACGGIADNIIK
CCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCEEEECCCHHHHEE
CVAISPQMRGEGLALRLATELVNLAYERHHTQLFIYTKIQNEPLFRQCGFYPIAQVPGIV
EEEECCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHCCCCCHHHCCEEE
VLMENSPCRLKRYAAQLAGQRQPGKRIGSIVMNANPFTRGHQYLVRQAAEKCDWLHLFLV
EEECCCCHHHHHHHHHHCCCCCCCHHHCEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEE
KENTSRFSYEDRRRLVLAGTADIANLTVHEGSQYVISRATFPCYFIKDQGIADDCYTEID
ECCCCCCCCCCCCEEEEEECCCEEEEEEECCCEEEEEECCCCEEEEECCCCCCHHHHHHH
LKIFRQYLAPALGITHRFVGNEPFCAVTAKYNRDMRYWLETPALSSPPIALVEIERLQYQ
HHHHHHHHHHHHCCHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEEEHEEC
GTAISASWVRKLLAAGDFHAAAPLVPPDTLYYLQDLQTQRRAKPAATPFESAQSGER
CCEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLGDAIFDRVKRSDHKNITQINAFLRSNDLNIDTTVEIFITVTQNDKLVACGGIADNIIK
CCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCEEEECCCHHHHEE
CVAISPQMRGEGLALRLATELVNLAYERHHTQLFIYTKIQNEPLFRQCGFYPIAQVPGIV
EEEECCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHCCCCCHHHCCEEE
VLMENSPCRLKRYAAQLAGQRQPGKRIGSIVMNANPFTRGHQYLVRQAAEKCDWLHLFLV
EEECCCCHHHHHHHHHHCCCCCCCHHHCEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEE
KENTSRFSYEDRRRLVLAGTADIANLTVHEGSQYVISRATFPCYFIKDQGIADDCYTEID
ECCCCCCCCCCCCEEEEEECCCEEEEEEECCCEEEEEECCCCEEEEECCCCCCHHHHHHH
LKIFRQYLAPALGITHRFVGNEPFCAVTAKYNRDMRYWLETPALSSPPIALVEIERLQYQ
HHHHHHHHHHHHCCHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEEEHEEC
GTAISASWVRKLLAAGDFHAAAPLVPPDTLYYLQDLQTQRRAKPAATPFESAQSGER
CCEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]