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The map label for this gene is hypE [H]

Identifier: 157370679

GI number: 157370679

Start: 2671303

End: 2672316

Strand: Direct

Name: hypE [H]

Synonym: Spro_2439

Alternate gene names: 157370679

Gene position: 2671303-2672316 (Clockwise)

Preceding gene: 157370678

Following gene: 157370680

Centisome position: 49.03

GC content: 60.26

Gene sequence:

>1014_bases
ATGAATAACGTGATTACTATGGCGCACGGCAGCGGCGGCAGCGCGATGCAGCAACTGCTGGATGAGATTTTCTTGCCGGC
CTTTGCCAATCCGCTGCTGGATCAACGTGAAGATCAGGCCCGGTTGGATTTGGCCGAATTAACGCAGCAGGGCGATCGGC
TGGCGTTTACTACCGACAGCTACGTGATTGATCCGATTTTCTTCCCGGGCGGTGATATTGGCAAACTGGCGGTCTGCGGG
ACGGCTAACGATCTGGCGGTCAGCGGCGCGTTACCGCGCTATCTTTCCTGCGGGTTTATCCTCGAAGAAGGTTTGCCGCT
GGTTGATTTACAACGGCTGGTGGCTTCGATGGCGGCCACTGCGCAGCAGGCCGGTATCCGCATTGTGACCGGGGATACCA
AGGTGGTGCAGCGCGGCGCGGCCGACAAAGTGTTTATCAACACCGCCGGTATTGGGGTGATCCCGCCGGACCTGGATTGG
GCAGCGCAAAATATTCGCGTCGGTGACGCGGTGATTGTCAGCGGTACGCTCGGCGATCACGGGGCGACGATCCTCAACCT
GCGGGAAAAGCTGGGCATGTCGCTGGATGTGATCAGCGATTGCGCGGTGTTGGCTCCGTTAATCACGCCATTACGTGGCA
TTAACGGCGTGCGAGCCATGCGCGATGCTACCCGTGGTGGAGTGAACGCCATCCTGCATGAGTTTGCTCGTGCGGCGGGC
GCGGGGATTGAAGTTGAAGAGAACCTGTTACCGATAGCGCCGGCAGTGCGAGGGATTTGCGAGTTGCTGGGGCTGGATGC
CATCAACTTTGCCAACGAGGGCAAGCTGGTGGTGGTGGCCGCGCCGGAAGCCGAACAGGCGGTACTGGCTGCGTTACAGG
CGCATCCGCTGGGCAAGGCCGCGGCATTGATTGGCCGGGTGACTGCCGGACGACAAGTGAGGCTGCAGGGCGCTTATGGC
ATCAGCCGCCTGCTGGATTTGCCGCATGCCGAACCTTTGCCGCGCATTTGTTGA

Upstream 100 bases:

>100_bases
ACTGTACACCGCAAAATGCTTTTGGCGCGTTGATGGTGTCTTCGGAAGGTGCCTGCGCCGCCTGGTACCAATACCGTCGT
GAAACAGAGGAAACCCCGGC

Downstream 100 bases:

>100_bases
TCCTGTCGGGGGAGAACCTTGTCGCCCAGCGTTACACTTTGTGACGTGACTCACTAAAATCATCATCGCGACTCAGGCAA
GTGATAAACAATGTCGAATG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNNVITMAHGSGGSAMQQLLDEIFLPAFANPLLDQREDQARLDLAELTQQGDRLAFTTDSYVIDPIFFPGGDIGKLAVCG
TANDLAVSGALPRYLSCGFILEEGLPLVDLQRLVASMAATAQQAGIRIVTGDTKVVQRGAADKVFINTAGIGVIPPDLDW
AAQNIRVGDAVIVSGTLGDHGATILNLREKLGMSLDVISDCAVLAPLITPLRGINGVRAMRDATRGGVNAILHEFARAAG
AGIEVEENLLPIAPAVRGICELLGLDAINFANEGKLVVVAAPEAEQAVLAALQAHPLGKAAALIGRVTAGRQVRLQGAYG
ISRLLDLPHAEPLPRIC

Sequences:

>Translated_337_residues
MNNVITMAHGSGGSAMQQLLDEIFLPAFANPLLDQREDQARLDLAELTQQGDRLAFTTDSYVIDPIFFPGGDIGKLAVCG
TANDLAVSGALPRYLSCGFILEEGLPLVDLQRLVASMAATAQQAGIRIVTGDTKVVQRGAADKVFINTAGIGVIPPDLDW
AAQNIRVGDAVIVSGTLGDHGATILNLREKLGMSLDVISDCAVLAPLITPLRGINGVRAMRDATRGGVNAILHEFARAAG
AGIEVEENLLPIAPAVRGICELLGLDAINFANEGKLVVVAAPEAEQAVLAALQAHPLGKAAALIGRVTAGRQVRLQGAYG
ISRLLDLPHAEPLPRIC
>Mature_337_residues
MNNVITMAHGSGGSAMQQLLDEIFLPAFANPLLDQREDQARLDLAELTQQGDRLAFTTDSYVIDPIFFPGGDIGKLAVCG
TANDLAVSGALPRYLSCGFILEEGLPLVDLQRLVASMAATAQQAGIRIVTGDTKVVQRGAADKVFINTAGIGVIPPDLDW
AAQNIRVGDAVIVSGTLGDHGATILNLREKLGMSLDVISDCAVLAPLITPLRGINGVRAMRDATRGGVNAILHEFARAAG
AGIEVEENLLPIAPAVRGICELLGLDAINFANEGKLVVVAAPEAEQAVLAALQAHPLGKAAALIGRVTAGRQVRLQGAYG
ISRLLDLPHAEPLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=70.0296735905044, Blast_Score=487, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35234; Mature: 35234

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNVITMAHGSGGSAMQQLLDEIFLPAFANPLLDQREDQARLDLAELTQQGDRLAFTTDS
CCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCHHHHHCCCCEEEEEECC
YVIDPIFFPGGDIGKLAVCGTANDLAVSGALPRYLSCGFILEEGLPLVDLQRLVASMAAT
EEEEEEECCCCCCCCEEEECCCCCCEECCCCHHHHHCCHHHHCCCCHHHHHHHHHHHHHH
AQQAGIRIVTGDTKVVQRGAADKVFINTAGIGVIPPDLDWAAQNIRVGDAVIVSGTLGDH
HHHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCEEECCEEEEECCCCCC
GATILNLREKLGMSLDVISDCAVLAPLITPLRGINGVRAMRDATRGGVNAILHEFARAAG
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHC
AGIEVEENLLPIAPAVRGICELLGLDAINFANEGKLVVVAAPEAEQAVLAALQAHPLGKA
CCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHH
AALIGRVTAGRQVRLQGAYGISRLLDLPHAEPLPRIC
HHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNNVITMAHGSGGSAMQQLLDEIFLPAFANPLLDQREDQARLDLAELTQQGDRLAFTTDS
CCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCHHHHHCCCCEEEEEECC
YVIDPIFFPGGDIGKLAVCGTANDLAVSGALPRYLSCGFILEEGLPLVDLQRLVASMAAT
EEEEEEECCCCCCCCEEEECCCCCCEECCCCHHHHHCCHHHHCCCCHHHHHHHHHHHHHH
AQQAGIRIVTGDTKVVQRGAADKVFINTAGIGVIPPDLDWAAQNIRVGDAVIVSGTLGDH
HHHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCEEECCEEEEECCCCCC
GATILNLREKLGMSLDVISDCAVLAPLITPLRGINGVRAMRDATRGGVNAILHEFARAAG
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHC
AGIEVEENLLPIAPAVRGICELLGLDAINFANEGKLVVVAAPEAEQAVLAALQAHPLGKA
CCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHH
AALIGRVTAGRQVRLQGAYGISRLLDLPHAEPLPRIC
HHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]