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The map label for this gene is hypD [H]

Identifier: 157370678

GI number: 157370678

Start: 2670179

End: 2671306

Strand: Direct

Name: hypD [H]

Synonym: Spro_2438

Alternate gene names: 157370678

Gene position: 2670179-2671306 (Clockwise)

Preceding gene: 157370677

Following gene: 157370679

Centisome position: 49.0

GC content: 58.33

Gene sequence:

>1128_bases
ATGCATTACGTTGATGAGTTCCGCGATCCGAAGCGGGTAAAAACCCTGTTGCAGCATATTCGGCAGCGAGCCGCACAGTT
GCCGTTTAGCGCTGAGCGGTCGTTGCAAATTATGGAAGTATGCGGTGGTCATACCCATGCCATTTTCCGCTTTGGCCTGG
ATAAACTGCTGCCGCCACAGATTGAATTTATTCATGGACCGGGCTGCCCGGTTTGTGTGTTGCCCATGGGGCGTATAGAT
GCCTGCTGTGAAATAGCCGCTCACCCGGAGGTGATTTTTTGCACCTTCGGCGACGCGTTGCGGGTACCGGGCAAACAAGG
CTCTTTACTGCAGGCCCGTGAGCGCGGCGCCGATGTGCGGGTGGTTTATTCGCCGTTGGATGCTCTGATGCTGGCGCGTC
AACACCCGCAGCGGCAGCTGGTGTTCTTTGCCCTGGGGTTTGAAACCACCATGCCGGTCACGGCGATCACCCTGCAGCAG
GCCCGGCTGGAAGGGTTGAATAACTTCAGCGTGTTTTGCCAGCACATCAGCCTGATCCCCACCTTGCGCAGCCTGTTGCA
ACAGCCGGATGTCCGCATCGACGGCTTTCTGGCGCCCGGCCACGTCAGTATGGTGATTGGTACCGCGCCGTATCACTTTA
TCAGTCGGCAATACCATAAACCGCTGGTGGTGACCGGCTTTGAACCGCTGGATATCCTGCAAGGGGTGATGATGCTGGTT
GAGCAGTTTGTGGGGCAGCAGAGCCAAACCGAGAACCAATACCGCCGGGTGGTACCTGAACAGGGCAATCTGCTGGCACA
GCAGGCGATGAGCGAAGTCTTTGTGCTGGGCGGCGGCAGCGAATGGCGCGGCCTTGGCACCATTGCTGATTCGGGTATTG
CCTTAACCCCGGCCTATAGCACCTTTGATGCGGAACGACGTTTCCGTCCGCAACACCGGCAGGTGGCTGACGATCCTCGT
GCCCGCTGTGGAGAGGTGCTGACCGGGCGTTGCAAACCGCGTGACTGCCCGCTGTTTGGTGGTGACTGTACACCGCAAAA
TGCTTTTGGCGCGTTGATGGTGTCTTCGGAAGGTGCCTGCGCCGCCTGGTACCAATACCGTCGTGAAACAGAGGAAACCC
CGGCATGA

Upstream 100 bases:

>100_bases
CGGCTCGACAGGCAGGAGGCCGAGGAGATGCTTTCGGCACTGCAGGCGATGGGGGAAGTGGAGCAGGACGTGGCGCTGTT
TTTGGCGGGGGAAGGCAACC

Downstream 100 bases:

>100_bases
ATAACGTGATTACTATGGCGCACGGCAGCGGCGGCAGCGCGATGCAGCAACTGCTGGATGAGATTTTCTTGCCGGCCTTT
GCCAATCCGCTGCTGGATCA

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MHYVDEFRDPKRVKTLLQHIRQRAAQLPFSAERSLQIMEVCGGHTHAIFRFGLDKLLPPQIEFIHGPGCPVCVLPMGRID
ACCEIAAHPEVIFCTFGDALRVPGKQGSLLQARERGADVRVVYSPLDALMLARQHPQRQLVFFALGFETTMPVTAITLQQ
ARLEGLNNFSVFCQHISLIPTLRSLLQQPDVRIDGFLAPGHVSMVIGTAPYHFISRQYHKPLVVTGFEPLDILQGVMMLV
EQFVGQQSQTENQYRRVVPEQGNLLAQQAMSEVFVLGGGSEWRGLGTIADSGIALTPAYSTFDAERRFRPQHRQVADDPR
ARCGEVLTGRCKPRDCPLFGGDCTPQNAFGALMVSSEGACAAWYQYRRETEETPA

Sequences:

>Translated_375_residues
MHYVDEFRDPKRVKTLLQHIRQRAAQLPFSAERSLQIMEVCGGHTHAIFRFGLDKLLPPQIEFIHGPGCPVCVLPMGRID
ACCEIAAHPEVIFCTFGDALRVPGKQGSLLQARERGADVRVVYSPLDALMLARQHPQRQLVFFALGFETTMPVTAITLQQ
ARLEGLNNFSVFCQHISLIPTLRSLLQQPDVRIDGFLAPGHVSMVIGTAPYHFISRQYHKPLVVTGFEPLDILQGVMMLV
EQFVGQQSQTENQYRRVVPEQGNLLAQQAMSEVFVLGGGSEWRGLGTIADSGIALTPAYSTFDAERRFRPQHRQVADDPR
ARCGEVLTGRCKPRDCPLFGGDCTPQNAFGALMVSSEGACAAWYQYRRETEETPA
>Mature_375_residues
MHYVDEFRDPKRVKTLLQHIRQRAAQLPFSAERSLQIMEVCGGHTHAIFRFGLDKLLPPQIEFIHGPGCPVCVLPMGRID
ACCEIAAHPEVIFCTFGDALRVPGKQGSLLQARERGADVRVVYSPLDALMLARQHPQRQLVFFALGFETTMPVTAITLQQ
ARLEGLNNFSVFCQHISLIPTLRSLLQQPDVRIDGFLAPGHVSMVIGTAPYHFISRQYHKPLVVTGFEPLDILQGVMMLV
EQFVGQQSQTENQYRRVVPEQGNLLAQQAMSEVFVLGGGSEWRGLGTIADSGIALTPAYSTFDAERRFRPQHRQVADDPR
ARCGEVLTGRCKPRDCPLFGGDCTPQNAFGALMVSSEGACAAWYQYRRETEETPA

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=373, Percent_Identity=71.0455764075067, Blast_Score=573, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41760; Mature: 41760

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYVDEFRDPKRVKTLLQHIRQRAAQLPFSAERSLQIMEVCGGHTHAIFRFGLDKLLPPQ
CCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCHHHHHHHHHHHHCCCC
IEFIHGPGCPVCVLPMGRIDACCEIAAHPEVIFCTFGDALRVPGKQGSLLQARERGADVR
EEEEECCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCEECCCCCCCHHHHHHCCCCEE
VVYSPLDALMLARQHPQRQLVFFALGFETTMPVTAITLQQARLEGLNNFSVFCQHISLIP
EEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
TLRSLLQQPDVRIDGFLAPGHVSMVIGTAPYHFISRQYHKPLVVTGFEPLDILQGVMMLV
HHHHHHHCCCCEEECEECCCCEEEEEECCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
EQFVGQQSQTENQYRRVVPEQGNLLAQQAMSEVFVLGGGSEWRGLGTIADSGIALTPAYS
HHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHEEEEECCCCCCCCEEECCCCEEEECCHH
TFDAERRFRPQHRQVADDPRARCGEVLTGRCKPRDCPLFGGDCTPQNAFGALMVSSEGAC
HCCHHHHCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCH
AAWYQYRRETEETPA
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MHYVDEFRDPKRVKTLLQHIRQRAAQLPFSAERSLQIMEVCGGHTHAIFRFGLDKLLPPQ
CCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCHHHHHHHHHHHHCCCC
IEFIHGPGCPVCVLPMGRIDACCEIAAHPEVIFCTFGDALRVPGKQGSLLQARERGADVR
EEEEECCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCEECCCCCCCHHHHHHCCCCEE
VVYSPLDALMLARQHPQRQLVFFALGFETTMPVTAITLQQARLEGLNNFSVFCQHISLIP
EEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
TLRSLLQQPDVRIDGFLAPGHVSMVIGTAPYHFISRQYHKPLVVTGFEPLDILQGVMMLV
HHHHHHHCCCCEEECEECCCCEEEEEECCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
EQFVGQQSQTENQYRRVVPEQGNLLAQQAMSEVFVLGGGSEWRGLGTIADSGIALTPAYS
HHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHEEEEECCCCCCCCEEECCCCEEEECCHH
TFDAERRFRPQHRQVADDPRARCGEVLTGRCKPRDCPLFGGDCTPQNAFGALMVSSEGAC
HCCHHHHCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCH
AAWYQYRRETEETPA
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]