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The map label for this gene is hypC [C]

Identifier: 157370677

GI number: 157370677

Start: 2669899

End: 2670192

Strand: Direct

Name: hypC [C]

Synonym: Spro_2437

Alternate gene names: 157370677

Gene position: 2669899-2670192 (Clockwise)

Preceding gene: 157370676

Following gene: 157370678

Centisome position: 49.0

GC content: 60.54

Gene sequence:

>294_bases
ATGTGCATAGGCGTTCCAGGGCAGATCGTGGCGCTGGATGAAAAGCAGCCTCAGCATGCCTGGGCCGAAGTCTGTGGTGT
GCAGCGGGAAGTGAATATTGCGCTGGTGCGTCAGGAGGGTGAACCCAGAGAAGCGATGATCGGCTGCTGGGTGCTGATCC
ACGTCGGCTTCGCCATGAGTCGGCTCGACAGGCAGGAGGCCGAGGAGATGCTTTCGGCACTGCAGGCGATGGGGGAAGTG
GAGCAGGACGTGGCGCTGTTTTTGGCGGGGGAAGGCAACCATGCATTACGTTGA

Upstream 100 bases:

>100_bases
ACAATGCCCGCAAGGTGAACCCGACGATTGAGGTGATTACCCTCTCGGCGACCAGCGGTGAAGGTATGGATCAGTGGCTG
GCCTGGCTGGAGACACAGTT

Downstream 100 bases:

>100_bases
TGAGTTCCGCGATCCGAAGCGGGTAAAAACCCTGTTGCAGCATATTCGGCAGCGAGCCGCACAGTTGCCGTTTAGCGCTG
AGCGGTCGTTGCAAATTATG

Product: hydrogenase assembly chaperone HypC/HupF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MCIGVPGQIVALDEKQPQHAWAEVCGVQREVNIALVRQEGEPREAMIGCWVLIHVGFAMSRLDRQEAEEMLSALQAMGEV
EQDVALFLAGEGNHALR

Sequences:

>Translated_97_residues
MCIGVPGQIVALDEKQPQHAWAEVCGVQREVNIALVRQEGEPREAMIGCWVLIHVGFAMSRLDRQEAEEMLSALQAMGEV
EQDVALFLAGEGNHALR
>Mature_97_residues
MCIGVPGQIVALDEKQPQHAWAEVCGVQREVNIALVRQEGEPREAMIGCWVLIHVGFAMSRLDRQEAEEMLSALQAMGEV
EQDVALFLAGEGNHALR

Specific function: Is Required For The Formation Of All Three Hydrogenase Isoenzymes. May Bind To The Precursor Form Of The Large Subunit Of Dehydrogenases To Keep Them In A Conformation Accessible For Metal Incorporation. [C]

COG id: COG0298

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hupF/hypC family [H]

Homologues:

Organism=Escherichia coli, GI1789083, Length=94, Percent_Identity=51.063829787234, Blast_Score=87, Evalue=2e-19,
Organism=Escherichia coli, GI1789364, Length=77, Percent_Identity=55.8441558441558, Blast_Score=82, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019812
- InterPro:   IPR001109 [H]

Pfam domain/function: PF01455 HupF_HypC [H]

EC number: NA

Molecular weight: Translated: 10682; Mature: 10682

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS01097 HUPF_HYPC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCIGVPGQIVALDEKQPQHAWAEVCGVQREVNIALVRQEGEPREAMIGCWVLIHVGFAMS
CEECCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
RLDRQEAEEMLSALQAMGEVEQDVALFLAGEGNHALR
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MCIGVPGQIVALDEKQPQHAWAEVCGVQREVNIALVRQEGEPREAMIGCWVLIHVGFAMS
CEECCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
RLDRQEAEEMLSALQAMGEVEQDVALFLAGEGNHALR
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3308458 [H]