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The map label for this gene is yjjL [H]

Identifier: 157369650

GI number: 157369650

Start: 1533023

End: 1534381

Strand: Reverse

Name: yjjL [H]

Synonym: Spro_1407

Alternate gene names: 157369650

Gene position: 1534381-1533023 (Counterclockwise)

Preceding gene: 157369651

Following gene: 157369647

Centisome position: 28.16

GC content: 55.48

Gene sequence:

>1359_bases
ATGGAAAGAAGTCATACGATTAATACCGGGAAGGAACAGGGTGAACCCTATTCCAATCACATAATTCCGATGCCGCCGGA
GGGAATACTGGTTCGTTCGGCCAGAATTAAAAAAATTCAAACCACGGCCATGTTGTTGTTATTTTTGGCAGCCATAATCA
ACTTTCTTGACCGCAGTTCGCTCTCGGTGGCGAACTCCACCATCCGGCAAGAAATGGGGCTGAGCGGTACCGAAATCGGC
TTGTTGCTGTCGGCATTCTCCCTGGCCTATGGCATCGCCCAGTTGCCCTGCGGCCTGCTGCTGGATCGTAAAGGTCCACG
CATCATGCTGGGGATCGGCATGTTTGTCTGGTCGGTATTCCAGACGCTGTCCGGCATGATCCACAACTTTACCCAATTTA
TCTGGGTACGTATCGGGCTGGGAATTGGCGAAGCCCCCATGAACCCGTGCGGCGTAAAGGTGATCAACGACTGGTTCAAT
ATCAAGGATCGCGGCATGCCGATGGGTATTTTTAATGCCGCTTCGACCATCGGGCTGGCGATCAGCCCACCGATCCTCAC
CGCCATGATGCTGGCCTTCGGTTGGCGCGGTATGTTTATCACCATCGGCGTATTGGGTATCGCACTGTCCATCGGCTGGT
ACATGCTGTACCGCAACCGACAGGACGTCAGCCTGAGCGCTCAGGAACAGGCCTATTTGAATGCCGGTAGCGTCAGCGCC
CGACCTGAACCAATGAACTTTCGCGAGTGGCGAGCGCTATTCAGGAACCGTACCATGTGGGGCATGATGATTGGCTTCAG
CGGCATTAACTACACCGCCTGGCTGTACCTGGCCTGGCTGCCGGGTTATCTGCAGACCACTTACCATCTGGATCTGAAAA
GCACCGGGCTGCTGAGTGCCATTCCGTTCCTGTTTGGTGCCGCCGGCATGTTGTCGAACGGCTTCGTCACCGACTTTTTG
GTACGTCGCGGCATGGCTCCGCTGAAAAGCCGCAAAATTTGCATCGTCGCCGGTATGCTGCTGTCCGCTTCCTTTACTGC
CGTGGTCGCTCAGGCCACCACCACCTACAGCGCGGTATTGTTGATCGGCATGGCGCTGTTTTGCATTCACTTTGCCGGTA
CCTCCTGCTGGGGCCTGATCCACGTGGCGGTGAATTCACGCATGACCGCTTCGGTCGGCAGCATTCAAAACTTCGCCAGC
TTTATCTTTGCCTCATTCGCGCCAGTGGTCACCGGTTGGATCCTGGATACCACCCACTCTTTCAGCCTGGCCCTTACCCT
CTGCTCCTGTTTTACCGTCATCGGCGCGCTGTCGTATATCTTCGTGGTTAAACACCCGATCGTTGACAGCGCCGCCTGA

Upstream 100 bases:

>100_bases
AGGCTTACTGCCGACCACCTGCTAATACCTTCATTAAGACACCACCCAGGGGAATACCCGGAATAATAAATATTATTAAT
GCGAAATTCTGGAGGATGAA

Downstream 100 bases:

>100_bases
CGCTCACCCAACAGAGGGCCGGCACTCAATTGAGGGTAAAGAAATCCAGCCCCAATGCGGCCTTCACCTGCCCCAGCGTT
TGCCGACTGACCTGGTCGGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MERSHTINTGKEQGEPYSNHIIPMPPEGILVRSARIKKIQTTAMLLLFLAAIINFLDRSSLSVANSTIRQEMGLSGTEIG
LLLSAFSLAYGIAQLPCGLLLDRKGPRIMLGIGMFVWSVFQTLSGMIHNFTQFIWVRIGLGIGEAPMNPCGVKVINDWFN
IKDRGMPMGIFNAASTIGLAISPPILTAMMLAFGWRGMFITIGVLGIALSIGWYMLYRNRQDVSLSAQEQAYLNAGSVSA
RPEPMNFREWRALFRNRTMWGMMIGFSGINYTAWLYLAWLPGYLQTTYHLDLKSTGLLSAIPFLFGAAGMLSNGFVTDFL
VRRGMAPLKSRKICIVAGMLLSASFTAVVAQATTTYSAVLLIGMALFCIHFAGTSCWGLIHVAVNSRMTASVGSIQNFAS
FIFASFAPVVTGWILDTTHSFSLALTLCSCFTVIGALSYIFVVKHPIVDSAA

Sequences:

>Translated_452_residues
MERSHTINTGKEQGEPYSNHIIPMPPEGILVRSARIKKIQTTAMLLLFLAAIINFLDRSSLSVANSTIRQEMGLSGTEIG
LLLSAFSLAYGIAQLPCGLLLDRKGPRIMLGIGMFVWSVFQTLSGMIHNFTQFIWVRIGLGIGEAPMNPCGVKVINDWFN
IKDRGMPMGIFNAASTIGLAISPPILTAMMLAFGWRGMFITIGVLGIALSIGWYMLYRNRQDVSLSAQEQAYLNAGSVSA
RPEPMNFREWRALFRNRTMWGMMIGFSGINYTAWLYLAWLPGYLQTTYHLDLKSTGLLSAIPFLFGAAGMLSNGFVTDFL
VRRGMAPLKSRKICIVAGMLLSASFTAVVAQATTTYSAVLLIGMALFCIHFAGTSCWGLIHVAVNSRMTASVGSIQNFAS
FIFASFAPVVTGWILDTTHSFSLALTLCSCFTVIGALSYIFVVKHPIVDSAA
>Mature_452_residues
MERSHTINTGKEQGEPYSNHIIPMPPEGILVRSARIKKIQTTAMLLLFLAAIINFLDRSSLSVANSTIRQEMGLSGTEIG
LLLSAFSLAYGIAQLPCGLLLDRKGPRIMLGIGMFVWSVFQTLSGMIHNFTQFIWVRIGLGIGEAPMNPCGVKVINDWFN
IKDRGMPMGIFNAASTIGLAISPPILTAMMLAFGWRGMFITIGVLGIALSIGWYMLYRNRQDVSLSAQEQAYLNAGSVSA
RPEPMNFREWRALFRNRTMWGMMIGFSGINYTAWLYLAWLPGYLQTTYHLDLKSTGLLSAIPFLFGAAGMLSNGFVTDFL
VRRGMAPLKSRKICIVAGMLLSASFTAVVAQATTTYSAVLLIGMALFCIHFAGTSCWGLIHVAVNSRMTASVGSIQNFAS
FIFASFAPVVTGWILDTTHSFSLALTLCSCFTVIGALSYIFVVKHPIVDSAA

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=405, Percent_Identity=20.9876543209877, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI9945322, Length=373, Percent_Identity=21.71581769437, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI6912666, Length=299, Percent_Identity=23.4113712374582, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI148743791, Length=353, Percent_Identity=24.3626062322946, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI9966811, Length=379, Percent_Identity=20.5804749340369, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI185136021, Length=458, Percent_Identity=24.0174672489083, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367379, Length=449, Percent_Identity=76.6146993318486, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1789515, Length=432, Percent_Identity=30.5555555555556, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI87082320, Length=428, Percent_Identity=29.9065420560748, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1789152, Length=421, Percent_Identity=28.5035629453682, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI2367193, Length=422, Percent_Identity=23.9336492890995, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI87082310, Length=406, Percent_Identity=23.3990147783251, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082071, Length=257, Percent_Identity=24.9027237354086, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17554148, Length=332, Percent_Identity=23.4939759036145, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533556, Length=410, Percent_Identity=22.4390243902439, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533554, Length=410, Percent_Identity=22.4390243902439, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141316, Length=443, Percent_Identity=21.4446952595937, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17566884, Length=183, Percent_Identity=28.4153005464481, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25141318, Length=385, Percent_Identity=21.5584415584416, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560030, Length=301, Percent_Identity=24.5847176079734, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554962, Length=332, Percent_Identity=22.5903614457831, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=363, Percent_Identity=21.4876033057851, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86561091, Length=378, Percent_Identity=20.8994708994709, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17535049, Length=452, Percent_Identity=22.1238938053097, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=250, Percent_Identity=22.8, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639764, Length=419, Percent_Identity=22.673031026253, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24641682, Length=414, Percent_Identity=24.3961352657005, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24583789, Length=262, Percent_Identity=24.8091603053435, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24654215, Length=364, Percent_Identity=25, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19922400, Length=371, Percent_Identity=24.5283018867925, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24648416, Length=390, Percent_Identity=22.5641025641026, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21356189, Length=390, Percent_Identity=22.5641025641026, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28573299, Length=401, Percent_Identity=23.4413965087282, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28573708, Length=385, Percent_Identity=23.3766233766234, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573707, Length=385, Percent_Identity=23.3766233766234, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864456, Length=357, Percent_Identity=22.1288515406162, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24654039, Length=357, Percent_Identity=22.1288515406162, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24584153, Length=321, Percent_Identity=23.3644859813084, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550364, Length=300, Percent_Identity=24.6666666666667, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24655271, Length=436, Percent_Identity=21.7889908256881, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20130135, Length=409, Percent_Identity=22.2493887530562, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24654037, Length=383, Percent_Identity=22.4543080939948, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24654041, Length=383, Percent_Identity=22.4543080939948, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45550460, Length=393, Percent_Identity=23.4096692111959, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130167, Length=303, Percent_Identity=21.1221122112211, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49358; Mature: 49358

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSHTINTGKEQGEPYSNHIIPMPPEGILVRSARIKKIQTTAMLLLFLAAIINFLDRSS
CCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSVANSTIRQEMGLSGTEIGLLLSAFSLAYGIAQLPCGLLLDRKGPRIMLGIGMFVWSVF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEHHHHHHHHHH
QTLSGMIHNFTQFIWVRIGLGIGEAPMNPCGVKVINDWFNIKDRGMPMGIFNAASTIGLA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCEE
ISPPILTAMMLAFGWRGMFITIGVLGIALSIGWYMLYRNRQDVSLSAQEQAYLNAGSVSA
ECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHCCCCCCC
RPEPMNFREWRALFRNRTMWGMMIGFSGINYTAWLYLAWLPGYLQTTYHLDLKSTGLLSA
CCCCCCHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHH
IPFLFGAAGMLSNGFVTDFLVRRGMAPLKSRKICIVAGMLLSASFTAVVAQATTTYSAVL
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
LIGMALFCIHFAGTSCWGLIHVAVNSRMTASVGSIQNFASFIFASFAPVVTGWILDTTHS
HHHHHHHHHHHCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
FSLALTLCSCFTVIGALSYIFVVKHPIVDSAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MERSHTINTGKEQGEPYSNHIIPMPPEGILVRSARIKKIQTTAMLLLFLAAIINFLDRSS
CCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSVANSTIRQEMGLSGTEIGLLLSAFSLAYGIAQLPCGLLLDRKGPRIMLGIGMFVWSVF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEHHHHHHHHHH
QTLSGMIHNFTQFIWVRIGLGIGEAPMNPCGVKVINDWFNIKDRGMPMGIFNAASTIGLA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCEE
ISPPILTAMMLAFGWRGMFITIGVLGIALSIGWYMLYRNRQDVSLSAQEQAYLNAGSVSA
ECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHCCCCCCC
RPEPMNFREWRALFRNRTMWGMMIGFSGINYTAWLYLAWLPGYLQTTYHLDLKSTGLLSA
CCCCCCHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHH
IPFLFGAAGMLSNGFVTDFLVRRGMAPLKSRKICIVAGMLLSASFTAVVAQATTTYSAVL
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
LIGMALFCIHFAGTSCWGLIHVAVNSRMTASVGSIQNFASFIFASFAPVVTGWILDTTHS
HHHHHHHHHHHCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
FSLALTLCSCFTVIGALSYIFVVKHPIVDSAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]