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The map label for this gene is idnK [H]

Identifier: 157163743

GI number: 157163743

Start: 4530752

End: 4531315

Strand: Direct

Name: idnK [H]

Synonym: EcHS_A4524

Alternate gene names: 157163743

Gene position: 4530752-4531315 (Clockwise)

Preceding gene: 157163737

Following gene: 157163745

Centisome position: 97.57

GC content: 43.62

Gene sequence:

>564_bases
ATGGCGGGTGAAAGCTTTATTTTGATGGGCGTTTCAGGGAGTGGTAAAACATTAATTGGTAGCAAGGTTGCCGCGTTATT
ATCTGCTAAATTTATTGATGGTGACGATCTTCATCCAGCCAAAAATATAGATAAAATGTCGCAGGGTATTCCATTATCTG
ATGAAGATCGACTTCCCTGGCTGGAACGCTTAAATGATGCTTCATACAGTCTTTATAAAAAGAATGAAACAGGATTTATT
GTCTGTTCATCATTAAAAAAACATTATCGTGATATTTTACGCAAGGGTAGCCCCCATGTTCATTTCCTCTGGTTAGATGG
CGACTATGAAACTATCCTCGCGCGAATGCAGCGTCGGGCTGGGCATTTTATGCCGGTAGCGTTACTAAAAAGTCAGTTTG
AGGCGCTGGAGCGTCCACAAGCAGATGAACAGGATATTGTGCGCATTGATATCAACCATGATATTGCCAATGTCACCGAA
CAATGTCGGCAGGCTGTGCTGGCGATACGACAAAACAGAATATGTGCGAAAGAGGGCAGCGCCTCAGATCAGCGCTGCGA
ATGA

Upstream 100 bases:

>100_bases
ATGTGCCTTGTAATTCTTATCAGCAGAAATAAAAAAACGTGAAATTATTATGCCACCAGGCGTAGTATCGCAGCAGGTAA
GATGATTCAGGAGATTTTAA

Downstream 100 bases:

>100_bases
TTTTCAAAAATCGGCTTTCAACACCACGCGGTAACGCGCCTTACCGTCGCGCACATGCTGGATGGCGTCGTTAATTTTCG
ACATCGGGAACAGTTCGGTT

Product: D-gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase 1 [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFI
VCSSLKKHYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTE
QCRQAVLAIRQNRICAKEGSASDQRCE

Sequences:

>Translated_187_residues
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFI
VCSSLKKHYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTE
QCRQAVLAIRQNRICAKEGSASDQRCE
>Mature_186_residues
AGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIV
CSSLKKHYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQ
CRQAVLAIRQNRICAKEGSASDQRCE

Specific function: Gluconate utilization system GNT-II. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=172, Percent_Identity=39.5348837209302, Blast_Score=130, Evalue=7e-31,
Organism=Escherichia coli, GI1790719, Length=187, Percent_Identity=99.4652406417112, Blast_Score=387, Evalue=1e-109,
Organism=Escherichia coli, GI87082265, Length=161, Percent_Identity=47.8260869565217, Blast_Score=180, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI25146487, Length=156, Percent_Identity=39.7435897435897, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6320454, Length=158, Percent_Identity=37.3417721518987, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 21013; Mature: 20882

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPW
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCH
LERLNDASYSLYKKNETGFIVCSSLKKHYRDILRKGSPHVHFLWLDGDYETILARMQRRA
HHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
GHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQCRQAVLAIRQNRICAKEGS
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
ASDQRCE
CCCCCCC
>Mature Secondary Structure 
AGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPW
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCH
LERLNDASYSLYKKNETGFIVCSSLKKHYRDILRKGSPHVHFLWLDGDYETILARMQRRA
HHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
GHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQCRQAVLAIRQNRICAKEGS
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
ASDQRCE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]