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The map label for this gene is lptG

Identifier: 157163737

GI number: 157163737

Start: 4523477

End: 4524559

Strand: Direct

Name: lptG

Synonym: EcHS_A4518

Alternate gene names: 157163737

Gene position: 4523477-4524559 (Clockwise)

Preceding gene: 157163736

Following gene: 157163743

Centisome position: 97.41

GC content: 54.11

Gene sequence:

>1083_bases
ATGCAACCTTTTGGCGTACTTGACCGCTATATCGGTAAAACTATTTTCACCACCATCATGATGACGCTGTTCATGCTGGT
GTCGCTGTCGGGCATTATCAAGTTTGTCGATCAGCTGAAAAAAGCCGGGCAGGGGAGTTACGACGCGTTAGGCGCAGGAA
TGTATACCTTGCTGAGCGTGCCGAAAGATGTGCAAATCTTCTTCCCGATGGCAGCTCTGCTTGGGGCGTTGCTTGGTCTT
GGGATGCTGGCGCAGCGCAGCGAACTGGTGGTGATGCAGGCTTCTGGTTTCACCCGTATGCAGGTTGCGCTGTCGGTGAT
GAAAACCGCCATTCCGCTAGTCTTGCTGACGATGGCGATTGGTGAATGGGTCGCGCCGCAGGGCGAGCAGATGGCGCGTA
ACTACCGTGCGCAGGCGATGTACGGCGGCTCGTTGCTCTCTACCCAGCAAGGCTTATGGGCGAAAGATGGCAACAACTTC
GTCTACATTGAGCGGGTTAAAGGTGACGAAGAGTTAGGTGGCATCAGCATTTATGCCTTTAACGAAAATCGTCGTCTGCA
ATCCGTACGCTATGCCGCTACTGCGAAGTTTGACCCGGAACATAAAGTCTGGCGTCTGTCGCAGGTTGATGAATCTGATC
TGACCAATCCGAAACAGATCACCGGTTCGCAGACGGTGAGCGGCACCTGGAAAACCAACCTCACGCCAGACAAACTGGGC
GTGGTGGCGCTGGACCCGGATGCACTCTCAATCAGCGGTTTGCACAACTACGTGAAGTATCTGAAGTCGAGCGGTCAGGA
CGCTGGACGTTATCAGCTCAACATGTGGAGCAAAATCTTCCAGCCGCTATCCGTGGCGGTGATGATGCTGATGGCGCTGT
CGTTCATCTTTGGCCCACTGCGTAGCGTACCGATGGGCGTGCGTGTGGTCACCGGTATCAGCTTCGGTTTTGTCTTCTAC
GTACTGGACCAGATCTTCGGCCCGTTGACGTTGGTTTATGGCATCCCGCCGATCATCGGCGCACTGTTGCCAAGCGCCAG
CTTCTTCTTAATCAGCCTGTGGCTGTTAATGAGAAAATCGTAA

Upstream 100 bases:

>100_bases
TTAACCTGATTTATCTGGCTTTGGCGATTGTTCTCAACCTTTGGGACACCGTGCCGGTCCGCCGCCTGCGCGCCAGTTTT
TCGCGTAAAGGAGCGGTGTG

Downstream 100 bases:

>100_bases
TCTAATGAACGCATAAAGGGAGCGAAAGCTCCCTTTCACATTGTTGATAAAGTCAAATACGAGTTCGATCGGTCCTCTCG
CCCCTTTGGGGAGAGGGTTA

Product: putative permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGL
GMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLG
VVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFY
VLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS

Sequences:

>Translated_360_residues
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGL
GMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLG
VVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFY
VLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>Mature_360_residues
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGL
GMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLG
VVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFY
VLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS

Specific function: Part of the ABC transporter complex lptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane

COG id: COG0795

COG function: function code R; Predicted permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptF/lptG family

Homologues:

Organism=Escherichia coli, GI87082400, Length=360, Percent_Identity=100, Blast_Score=727, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPTG_ECOL6 (P0ADC7)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_757211.1
- ProteinModelPortal:   P0ADC7
- EnsemblBacteria:   EBESCT00000044236
- GeneID:   1037318
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c5363
- GeneTree:   EBGT00050000011697
- HOGENOM:   HBG701346
- OMA:   LGQWGAP
- ProtClustDB:   PRK15071
- GO:   GO:0006810
- InterPro:   IPR005495

Pfam domain/function: PF03739 YjgP_YjgQ

EC number: NA

Molecular weight: Translated: 39619; Mature: 39619

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x198ad334)-; HASH(0x40552b24)-; HASH(0x198d4580)-; HASH(0x18e6a760)-; HASH(0x1986b338)-; HASH(0x195d4d84)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
PKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAF
HHHCCCCHHHHHHHHHHHHHCCCCHHHCCCCCEEECCCCEEEEEEECCCCCCCCEEEEEE
NENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLG
CCCCHHHHHHHHHCCCCCCCHHHEEECCCCCCCCCCCHHCCCCCEECCCEECCCCCCCCE
VVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPL
EEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
PKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAF
HHHCCCCHHHHHHHHHHHHHCCCCHHHCCCCCEEECCCCEEEEEEECCCCCCCCEEEEEE
NENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLG
CCCCHHHHHHHHHCCCCCCCHHHEEECCCCCCCCCCCHHCCCCCEECCCEECCCCCCCCE
VVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPL
EEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157