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The map label for this gene is hflX [H]

Identifier: 157163636

GI number: 157163636

Start: 4425408

End: 4426688

Strand: Direct

Name: hflX [H]

Synonym: EcHS_A4415

Alternate gene names: 157163636

Gene position: 4425408-4426688 (Clockwise)

Preceding gene: 157163635

Following gene: 157163637

Centisome position: 95.3

GC content: 53.79

Gene sequence:

>1281_bases
TTGTTTGACCGTTATGATGCTGGTGAGCAGGCGGTACTGGTACACATCTATTTTACGCAAGACAAAGATATGGAAGACCT
CCAGGAGTTTGAATCTCTGGTCTCTTCCGCCGGTGTCGAAGCATTGCAGGTGATTACCGGTAGCCGTAAAGCGCCGCACC
CAAAGTATTTTGTAGGTGAAGGTAAAGCAGTTGAAATTGCGGAAGCTGTCAAAGCGACGGGTGCTTCGGTCGTTCTTTTT
GACCATGCCCTGAGCCCGGCGCAAGAGCGTAACCTGGAGCGTTTGTGCGAGTGTCGTGTTATCGACCGCACCGGCCTTAT
TTTAGATATTTTCGCCCAACGTGCGCGTACCCATGAGGGTAAGTTGCAGGTTGAGCTGGCGCAGCTGCGCCATCTGGCTA
CGCGCCTGGTGCGTGGCTGGACCCACCTTGAAAGACAGAAAGGCGGGATAGGTTTGCGTGGTCCGGGTGAAACCCAGCTC
GAAACCGACCGTCGTTTGTTGCGTAATCGCATCGTGCAGATACAGTCGCGCCTGGAAAGAGTTGAAAAGCAGCGTGAGCA
GGGGCGGCAATCGCGTATCAAAGCCGACGTTCCTACTGTTTCGCTGGTGGGATATACCAACGCCGGTAAATCTACCCTTT
TCAATCGCATCACCGAAGCGCGGGTCTACGCGGCAGACCAGTTGTTTGCCACCCTCGACCCGACGTTGCGGCGTATTGAC
GTTGCAGATGTCGGTGAAACCGTGTTGGCAGATACCGTAGGGTTTATTCGCCACCTGCCGCACGATCTGGTTGCAGCATT
TAAAGCCACGTTACAAGAGACGCGGCAAGCCACATTACTGCTGCACGTCATTGATGCGGCGGATGTGCGTGTACAAGAAA
ACATCGAAGCGGTGAATACGGTTCTTGAAGAGATCGACGCTCACGAGATCCCAACCCTGCTGGTGATGAACAAGATCGAT
ATGCTGGAAGATTTCGAACCGCGTATTGATCGGGACGAAGAGAACAAACCGATCCGTGTCTGGCTTTCCGCACAGACCGG
AGCGGGGATACCACAGCTTTTTCAGGCTTTGACGGAGCGGCTTTCCGGCGAGGTGGCGCAGCATACATTGCGTCTGCCAC
CGCAGGAAGGGCGTCTGAGAAGTCGTTTTTATCAGCTTCAGGCAATAGAAAAAGAGTGGATGGAGGAGGACGGCAGCGTA
AGTCTGCAAGTTCGTATGCCGATCGTTGACTGGCGTCGCCTCTGTAAACAAGAACCGGCGTTGATCGATTACCTGATCTA
A

Upstream 100 bases:

>100_bases
ACAGGACAGCGAAGAAACCGAATAAGGTTTCGGGCTGTTTTTTTACACGGGGAGCCAGCGATCCTGCGTTCCCCGCTGAT
CTATTTAGAGGGTTATACGC

Downstream 100 bases:

>100_bases
CGGCGTAGCGTCTGAAGCGTGGAGTCATATCCTCTGGCGTCGAAAGACAACAGGGATCACCGCATAACAAATATGGAGCA
CAAACATGGCGTGGAATCAG

Product: putative GTPase HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLF
DHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRID
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKID
MLEDFEPRIDRDEENKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV
SLQVRMPIVDWRRLCKQEPALIDYLI

Sequences:

>Translated_426_residues
MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLF
DHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRID
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKID
MLEDFEPRIDRDEENKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV
SLQVRMPIVDWRRLCKQEPALIDYLI
>Mature_426_residues
MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLF
DHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRID
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKID
MLEDFEPRIDRDEENKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV
SLQVRMPIVDWRRLCKQEPALIDYLI

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=286, Percent_Identity=31.1188811188811, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310133116, Length=280, Percent_Identity=30.3571428571429, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI310124269, Length=262, Percent_Identity=30.5343511450382, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI310124267, Length=262, Percent_Identity=30.5343511450382, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI310124171, Length=262, Percent_Identity=30.5343511450382, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI310124169, Length=262, Percent_Identity=30.5343511450382, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI1790615, Length=426, Percent_Identity=99.7652582159624, Blast_Score=862, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561038, Length=296, Percent_Identity=29.0540540540541, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24650079, Length=284, Percent_Identity=31.3380281690141, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48327; Mature: 48327

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQVITGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECC
GKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEG
CCEEHHHHHHHHCCCEEEEEECCCCCHHHHCHHHHHHHEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRNRIVQIQSRLER
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRID
HHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNT
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEHHHHCHHHHHHHHHHHH
VLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENKPIRVWLSAQTGAGIPQLFQALTER
HHHHHCHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
LSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSVSLQVRMPIVDWRRLCKQEPA
HCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCC
LIDYLI
HHHHCC
>Mature Secondary Structure
MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQVITGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECC
GKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEG
CCEEHHHHHHHHCCCEEEEEECCCCCHHHHCHHHHHHHEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRNRIVQIQSRLER
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRID
HHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
VADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNT
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEHHHHCHHHHHHHHHHHH
VLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENKPIRVWLSAQTGAGIPQLFQALTER
HHHHHCHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
LSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSVSLQVRMPIVDWRRLCKQEPA
HCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCC
LIDYLI
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]