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The map label for this gene is hfq [H]

Identifier: 157163635

GI number: 157163635

Start: 4425024

End: 4425332

Strand: Direct

Name: hfq [H]

Synonym: EcHS_A4414

Alternate gene names: 157163635

Gene position: 4425024-4425332 (Clockwise)

Preceding gene: 157163634

Following gene: 157163636

Centisome position: 95.29

GC content: 48.54

Gene sequence:

>309_bases
ATGGCTAAGGGGCAATCTTTACAAGATCCGTTCCTGAACGCACTGCGTCGGGAACGTGTTCCAGTTTCTATTTATTTGGT
GAATGGTATTAAGCTGCAAGGGCAAATCGAGTCTTTTGATCAGTTCGTGATCCTGTTGAAAAACACGGTCAGCCAGATGG
TTTACAAGCACGCGATTTCTACTGTTGTCCCGTCTCGTCCGGTTTCTCATCACAGTAACAACGCCGGTGGCGGTACCAGC
AGTAACTACCATCATGGTAGCAGCGCGCAGAATACTTCCGCGCAACAGGACAGCGAAGAAACCGAATAA

Upstream 100 bases:

>100_bases
GCTATCGCAGGCTGAATGTGTACAATTGAGACGTATCGTGCGCAATTTTTTCAGAATCGAAAGGTTCAAAGTACAAATAA
GCATATAAGGAAAAGAGAGA

Downstream 100 bases:

>100_bases
GGTTTCGGGCTGTTTTTTTACACGGGGAGCCAGCGATCCTGCGTTCCCCGCTGATCTATTTAGAGGGTTATACGCTTGTT
TGACCGTTATGATGCTGGTG

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: HF-1; Host factor-I protein; HF-I [H]

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTS
SNYHHGSSAQNTSAQQDSEETE

Sequences:

>Translated_102_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTS
SNYHHGSSAQNTSAQQDSEETE
>Mature_101_residues
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSS
NYHHGSSAQNTSAQQDSEETE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=102, Percent_Identity=100, Blast_Score=210, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 11167; Mature: 11035

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA