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The map label for this gene is yjcD

Identifier: 157163534

GI number: 157163534

Start: 4310244

End: 4311593

Strand: Direct

Name: yjcD

Synonym: EcHS_A4307

Alternate gene names: 157163534

Gene position: 4310244-4311593 (Clockwise)

Preceding gene: 157163532

Following gene: 157163535

Centisome position: 92.82

GC content: 56.0

Gene sequence:

>1350_bases
ATGTCTACGCCATCAGCGCGTACCGGCGGTTCACTCGACGCCTGGTTTAAAATTTCACAACGTGGAAGCACTGTCCGTCA
GGAAGTGGTTGCCGGGTTAACAACGTTTCTGGCGATGGTCTACTCGGTCATCGTCGTTCCAGGTATGTTGGGTAAAGCAG
GCTTCCCGCCTGCGGCAGTTTTCGTTGCAACCTGTCTGGTTGCCGGACTCGGTTCTATCGTGATGGGTCTGTGGGCTAAT
CTGCCGTTGGCGATTGGTTGCGCCATCTCCCTGACGGCGTTTACCGCATTCAGCCTGGTGCTGGGGCAACATATTAGCGT
ACCTGTCGCGCTGGGTGCCGTGTTCCTGATGGGTGTGCTGTTTACGGTAATTTCTGCCACGGGTATCCGTAGCTGGATTT
TGCGCAACTTGCCTCACGGTGTGGCGCACGGCACGGGGATCGGTATCGGTCTGTTCCTGCTGCTCATTGCCGCTAATGGT
GTCGGTCTGGTGATTAAAAACCCGCTTGATGGTCTGCCCGTTGCGCTGGGTGATTTCGCGACCTTCCCGGTGATTATGTC
ACTGGTAGGTCTGGCGGTGATCATCGGCCTGGAAAAACTGAAAGTCCCTGGTGGCATTCTGCTGACCATTATCGGTATCT
CAATTGTCGGTTTGATCTTCGATCCTAACGTCCATTTCTCCGGCGTTTTCGCCATGCCTTCATTGAGCGATGAAAACGGC
AATTCACTGATTGGCAGCCTGGACATTATGGGCGCGCTGAATCCTGTAGTCCTGCCAAGCGTTCTGGCGCTGGTGATGAC
GGCAGTATTTGATGCCACCGGAACTATCCGTGCCGTCGCCGGCCAGGCGAACCTGCTGGATAAAGATGGGCAGATCATCG
ACGGTGGGAAAGCACTGACCACTGACTCCATGAGCAGCGTTTTCTCTGGCCTGGTGGGTGCTGCTCCGGCAGCGGTATAC
ATCGAGTCTGCGGCGGGTACGGCGGCGGGCGGTAAAACCGGTTTGACGGCTATCACCGTTGGCGTGCTGTTCCTGCTGAT
TCTGTTCCTCTCTCCGCTCTCTTACCTCGTTCCGGGGTATGCAACGGCTCCGGCGCTGATGTACGTTGGCCTGCTGATGC
TGAGCAACGTGGCGAAAATCGACTTTGCTGATTTTGTTGATGCGATGGCGGGTCTGGTTACGGCGGTATTCATCGTGCTG
ACCTGTAACATCGTAACAGGCATCATGATCGGCTTCGCGACTCTGGTGATTGGTCGTCTGGTTTCCGGCGAATGGCGCAA
GTTGAACATCGGTACGGTCGTTATCGCCGTGGCGCTGGTGACCTTCTATGCGGGTGGCTGGGCTATCTAA

Upstream 100 bases:

>100_bases
AAATTGTCGCAAACCTGGAGCAGGAAGATAACGTTTCGCTGGCAGGGGATTGTCCGCCACGCATCTTGACGAAAATTAAA
CTCTCAGGGGATGTTTTCTT

Downstream 100 bases:

>100_bases
TCTTTCATCGGATTCTGAAAACGGGTGGCAATGGCTGCCCGTTTTTATTTTCTCCGCACATTGTGTGAGCTTTTGCGATA
TTCTGAAAAAATGAGAATTC

Product: sulfate permease family inorganic anion transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWAN
LPLAIGCAISLTAFTAFSLVLGQHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
VGLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGLIFDPNVHFSGVFAMPSLSDENG
NSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVY
IESAAGTAAGGKTGLTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGLVTAVFIVL
TCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI

Sequences:

>Translated_449_residues
MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWAN
LPLAIGCAISLTAFTAFSLVLGQHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
VGLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGLIFDPNVHFSGVFAMPSLSDENG
NSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVY
IESAAGTAAGGKTGLTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGLVTAVFIVL
TCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI
>Mature_448_residues
STPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANL
PLAIGCAISLTAFTAFSLVLGQHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANGV
GLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGLIFDPNVHFSGVFAMPSLSDENGN
SLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYI
ESAAGTAAGGKTGLTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGLVTAVFIVLT
CNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily

Homologues:

Organism=Escherichia coli, GI1790499, Length=449, Percent_Identity=100, Blast_Score=861, Evalue=0.0,
Organism=Escherichia coli, GI48994909, Length=450, Percent_Identity=82.4444444444444, Blast_Score=708, Evalue=0.0,
Organism=Escherichia coli, GI87082309, Length=431, Percent_Identity=40.6032482598608, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1790150, Length=431, Percent_Identity=35.4988399071926, Blast_Score=253, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YJCD_ECO57 (P0AF53)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B86100
- PIR:   F91259
- RefSeq:   NP_290697.1
- RefSeq:   NP_313073.1
- ProteinModelPortal:   P0AF53
- EnsemblBacteria:   EBESCT00000028527
- EnsemblBacteria:   EBESCT00000058979
- GeneID:   914291
- GeneID:   960060
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5663
- KEGG:   ecs:ECs5046
- GeneTree:   EBGT00050000009705
- HOGENOM:   HBG750189
- OMA:   ENGEANA
- ProtClustDB:   CLSK870037
- BioCyc:   ECOL83334:ECS5046-MONOMER
- InterPro:   IPR006043
- PANTHER:   PTHR11119

Pfam domain/function: PF00860 Xan_ur_permease

EC number: NA

Molecular weight: Translated: 45712; Mature: 45581

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x188284b4)-; HASH(0x19287738)-; HASH(0x404f84e8)-; HASH(0x40519c8c)-; HASH(0x18fcd090)-; HASH(0x18c89308)-; HASH(0x4051c410)-; HASH(0x18e5b5dc)-; HASH(0x4050eff4)-; HASH(0x4050e760)-; HASH(0x18cb33a8)-; HASH(0x1906ce08)-; HASH(0x1888396c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCEEEEHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure 
STPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVIVVPGMLGKAGFPPAAV
CCCCCCCCCCHHHHEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
FVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLGQHISVPVALGAVFLMGVL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANGVGLVIKNPLDGLPVALGDFA
HHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHH
TFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGLIFDPNVHFSGVFAMPSLSDENG
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
NSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDGQIIDGGKALT
CCEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCCCCCCCEECCCCEEC
TDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTGLTAITVGVLFLLILFLSPLSYLVPGY
HHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
ATAPALMYVGLLMLSNVAKIDFADFVDAMAGLVTAVFIVLTCNIVTGIMIGFATLVIGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSGEWRKLNIGTVVIAVALVTFYAGGWAI
HCCCCEEEEHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796