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The map label for this gene is eprH [H]

Identifier: 157162314

GI number: 157162314

Start: 3017221

End: 3018402

Strand: Reverse

Name: eprH [H]

Synonym: EcHS_A3011

Alternate gene names: 157162314

Gene position: 3018402-3017221 (Counterclockwise)

Preceding gene: 157162317

Following gene: 157162313

Centisome position: 65.0

GC content: 33.08

Gene sequence:

>1182_bases
ATGGAAAATAATGATAAATTCTTATCACAAGACTTATTGGAATCTTATGCCATTCGTTTGTTGAGCGGACCATTGAATGG
ATGCGAGTATGAAATACTTAATGGGCGTCTACTTGTTATCATTGGTAATGATGTTTCGTTAGGAAGAAGTGATGCTTTTT
CTGAGTTACCAGAAAACACAATAGTCGTTCCTTATGGCGAGCTTACAGGTAGTTTTGAGATAATAATTACTACCGACCCT
GATATAGTAGTAACAATCAGAGAATTAACAGCACAAGAACCTGAAGATAGAACGTTAACATTCAATCAGCAAGTAGAAGT
TTTAGGTCTCAAATTTGCTGTAAAAGAAAAAAATGAAGTTTGGCAGTATTCATTGCCAGGCATTATTGAAAATAACATTA
TTTCTACAAAACAACATTTCTTTAGCAGTAAGCTGTTTAAGTATGTAATGCTTTTTTTTCTTTTTGCTATCATTTTCTTT
GCTTTTTATATTGTTAATGCCAGTAATGATCCGCAGCTGAGACATATCGATAAAATTCTTGTAAACAAAAACAGGAATTA
TGAAATTTTATATGGTAGAGATCATGTTATCTATATCAATACCAATAGTTTGGATGAAGCAGTCTGGGTCAAACAAGCAC
TGGAAAAAAATCAACCTGGAAAGCCAGTACGGGTGATAAATCCTGATGATGAATCGATACGAATTTTTTCATGGCTTGCT
GATAATTTCCCTGATTTACAATATTTTAAACTTCAGCTATTAGATGCCAGTAATCCCAGACTGACCGTGAGTAAGCAACG
GAATGCTATCACACAGCAACTAATCGACAATCTTATTAAAGGGTTACTACAAACTATGCCATATGCCAGCAATATAAGTA
TTGCGGTATTAGATGATAATGTATTGGAAAGTCAGGCTATTGAAACATTGTCAGCGATAGGTCTTTCTTATGAAAAATAT
AAAACAGCTAACAATGTGTATTTCAATATCATTGGTACGTTAAGTGACAGTGAATTAAATAAAATTAATAACTATGTTGA
CGAATATTATAAACAATGGGGTAAACAATATGTAAGATTTAATGTGAATTTGAAAAATCAGGACACAAATAATAGTTCAT
TTAGCTACGGAGATAACCGATTCGAGAAGTCTCAAGGTAGCAACTGGACGTTTCAGGAATAA

Upstream 100 bases:

>100_bases
TTATAATTTTTTATTCTGTATCATCATATTTTGGTCATGAAATTTCCGTCTTGTTACACTACTCTAAACTAGAGCTTATG
GAATTAGCGGGGGGGTATTC

Downstream 100 bases:

>100_bases
TTGAGGAGGACTTATAGCAGATTGGAATGGTTATATTATGGATATCAGCAAACAATTTGATCAGGGCGTTGATGATCTGA
ACCAGCAAGTTGAAAAAGCG

Product: type III secretion apparatus protein EprH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MENNDKFLSQDLLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENTIVVPYGELTGSFEIIITTDP
DIVVTIRELTAQEPEDRTLTFNQQVEVLGLKFAVKEKNEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFF
AFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNSLDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
DNFPDLQYFKLQLLDASNPRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGLSYEKY
KTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE

Sequences:

>Translated_393_residues
MENNDKFLSQDLLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENTIVVPYGELTGSFEIIITTDP
DIVVTIRELTAQEPEDRTLTFNQQVEVLGLKFAVKEKNEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFF
AFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNSLDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
DNFPDLQYFKLQLLDASNPRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGLSYEKY
KTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE
>Mature_393_residues
MENNDKFLSQDLLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENTIVVPYGELTGSFEIIITTDP
DIVVTIRELTAQEPEDRTLTFNQQVEVLGLKFAVKEKNEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFF
AFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNSLDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
DNFPDLQYFKLQLLDASNPRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGLSYEKY
KTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE

Specific function: Required for invasion of epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013387
- InterPro:   IPR019029 [H]

Pfam domain/function: PF09480 PrgH [H]

EC number: NA

Molecular weight: Translated: 45211; Mature: 45211

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNDKFLSQDLLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCCCCHHHHHCCCCC
IVVPYGELTGSFEIIITTDPDIVVTIRELTAQEPEDRTLTFNQQVEVLGLKFAVKEKNEV
EEEEECCCCCCEEEEEECCCCEEEEEEHHHCCCCCCCEEEECCCEEEEEEEEEEECCCCE
WQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFFAFYIVNASNDPQLRHIDKIL
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
VNKNRNYEILYGRDHVIYINTNSLDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
HCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEHH
DNFPDLQYFKLQLLDASNPRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDN
CCCCCCEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
VLESQAIETLSAIGLSYEKYKTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRF
HHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEE
NVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MENNDKFLSQDLLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCCCCHHHHHCCCCC
IVVPYGELTGSFEIIITTDPDIVVTIRELTAQEPEDRTLTFNQQVEVLGLKFAVKEKNEV
EEEEECCCCCCEEEEEECCCCEEEEEEHHHCCCCCCCEEEECCCEEEEEEEEEEECCCCE
WQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFFAFYIVNASNDPQLRHIDKIL
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
VNKNRNYEILYGRDHVIYINTNSLDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
HCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEHH
DNFPDLQYFKLQLLDASNPRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDN
CCCCCCEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
VLESQAIETLSAIGLSYEKYKTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRF
HHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEE
NVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]