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The map label for this gene is eprI [H]

Identifier: 157162313

GI number: 157162313

Start: 3016968

End: 3017183

Strand: Reverse

Name: eprI [H]

Synonym: EcHS_A3010

Alternate gene names: 157162313

Gene position: 3017183-3016968 (Counterclockwise)

Preceding gene: 157162314

Following gene: 157162312

Centisome position: 64.98

GC content: 38.89

Gene sequence:

>216_bases
ATGGATATCAGCAAACAATTTGATCAGGGCGTTGATGATCTGAACCAGCAAGTTGAAAAAGCGTTGGAGGTTTTAGCAAC
CAATCCCTCCGACCCGAAATTTCTTGCCGAATATCAAAGTGCATTAGCTGAGTATACATTATATCGAAATGCGCAATCTA
ACGTTGTAAAAGCGTATAAAGATCTTGATTCAGCAATCATACAAAACTTCCGCTAA

Upstream 100 bases:

>100_bases
TTTAGCTACGGAGATAACCGATTCGAGAAGTCTCAAGGTAGCAACTGGACGTTTCAGGAATAATTGAGGAGGACTTATAG
CAGATTGGAATGGTTATATT

Downstream 100 bases:

>100_bases
ACTGGATAAGGATTTTATTATGTCAGTAAGCAATATGCCACCTATTGATAGAGCTGAGCAATCAACTGCTCATGAAATAC
AGCAAGCGAAAGTGATTGAT

Product: type III secretion apparatus needle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 71; Mature: 71

Protein sequence:

>71_residues
MDISKQFDQGVDDLNQQVEKALEVLATNPSDPKFLAEYQSALAEYTLYRNAQSNVVKAYKDLDSAIIQNFR

Sequences:

>Translated_71_residues
MDISKQFDQGVDDLNQQVEKALEVLATNPSDPKFLAEYQSALAEYTLYRNAQSNVVKAYKDLDSAIIQNFR
>Mature_71_residues
MDISKQFDQGVDDLNQQVEKALEVLATNPSDPKFLAEYQSALAEYTLYRNAQSNVVKAYKDLDSAIIQNFR

Specific function: Required for invasion of epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mxiH/prgI/yscF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021123
- InterPro:   IPR011841 [H]

Pfam domain/function: PF09392 MxiH [H]

EC number: NA

Molecular weight: Translated: 8071; Mature: 8071

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISKQFDQGVDDLNQQVEKALEVLATNPSDPKFLAEYQSALAEYTLYRNAQSNVVKAYK
CCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLDSAIIQNFR
HHHHHHHHCCC
>Mature Secondary Structure
MDISKQFDQGVDDLNQQVEKALEVLATNPSDPKFLAEYQSALAEYTLYRNAQSNVVKAYK
CCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLDSAIIQNFR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]